Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Helen Liebling Jane
ID:
Sexual and Gender-Based Violence and Torture Experiences of South Sudanese Refugees in Northern Uganda: Health and Justice Responses
REFNo: SS126ES

Specific objectives are to:(1) examine the experiences of South Sudanese refugees and impact of Sexual and Gender-Based Violence (SGBV) and torture on their lives (2) analyse reproductive and psychological health,and justice needs of refugees from their own and service providers’ perspectives and (3) evaluate responses to refugees by state justice, health services and key stakeholders.
UK 2018-02-13 2021-02-13 Social Science and Humanities Non-degree Award
Helen Byakwaga
ID: UNCST-2019-R001168
 Study of Newly Diagnosed Kaposi's Sarcoma
REFNo: HS157ES

1) Describe the clinical and laboratory characteristics of HIV-infected patients who develop KS. 2) Determine survival after KS occurrence in both ART-treated and ART-untreated HIV-infected patients.
Uganda 2018-02-13 2021-02-13 Medical and Health Sciences Non-degree Award
Stephen Kyakulumbye
ID:
A framework for developing citizen-centric e-government applications in developing contexts: The design-reality gap
REFNo: IS9ES

To document a feasible participatory design methodology for citizen e-government applications.
 Uganda 2018-02-13 2021-02-13 Social Science and Humanities Degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
 Steady-state pharmacokinetics of efavirenz (Sustiva/Stocrin) 400 mg once daily in the presence of rifampicin and isoniazid (Rifinah or the local generics)
REFNo: HS161ES

Primary Objective: To evaluate the steady-state pharmacokinetics of efavirenz (Sustiva/Stocrin) 400 mg once daily during co-administration with rifampicin and isoniazid (Rifinah or local generic) Secondary Objectives: 1. To assess the safety and tolerability of efavirenz (Sustiva/Stocrin) 400 mg once daily during co-administration with rifampicin and isoniazid (Rifinah or local generic) 2. To investigate the association between genetic polymorphisms in drug disposition genes and drug exposure.
Nigeria 2018-02-06 2021-02-06 Medical and Health Sciences Non-degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
 A PHARMACOKINETIC EVALUATION OF ETONOGESTREL IMPLANT IN HIV-INFECTED WOMEN ON DARUNAVIR VERSUS RIPILVIRINE-BASED ANTIRETROVIRAL THERAPY (DRIVE-I)
REFNo: HS145ES

Primary objective: To compare the PK of ENG (68 mg) contraceptive implant over 6 months in Ugandan HIV-infected women receiving DRV-based ART or RPV-based ART versus historical controls Secondary objectives: (1) To predict the disposition of ENG over the subsequent 2.5 years of intended use through PK modeling of ENG concentrations beyond 12 months of use in HIV-infected women using DRV- or RPV-based ART (2) To describe the PK exposure over 12 months of ENG contraceptive implant in Ugandan HIV-infected women receiving DRV-based ART or RPV-based ART (3) To describe the pharmacokinetics of DRV 12 hours post-dose (C12) and RPV 24 hours post-dose (C24) prior to and during 12 months of combined use with ENG. (4) To describe the safety and tolerability of combined use of DRV/RTV or RPV and ENG during 12 months of combined use. (5) To describe the relationship between ENG concentrations and participant specific covariates including body weight, albumin, sex-hormone binding globulin and pharmacogenetic factors.
Nigeria 2018-01-29 2021-01-29 Medical and Health Sciences Non-degree Award
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