Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
The Integrated Management of Chronic Lung Illnesses in Uganda
REFNo: HS5728ES

Aim 1: To determine the prevalence of and factors associated with chronic respiratory illnesses e.g., asthma, chronic obstructive pulmonary disease among presumptive TB patients who test negative for TB on GeneXpert testing

Aim 2: (a) To determine the prevalence of, factors associated with post TB lung disease (PTLD) among patients who complete TB treatment (b) To determine the effect of post TB lung care on health related QoL among patients with PTLD

Aim 3: To determine barriers and facilitators for linkage to treatment for patients referred for chronic lung care

Aim 4: To document the cost per asthma/COPD case found during integrated community-based screening.
Uganda 2025-04-01 17:31:43 2028-04-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
george paasi
ID: UNCST-2020-R014619
THE CLINICAL SPECTRUM, GEOSPATIAL DISTRIBUTION AND GENETIC MODIFIERS OF SEVERE MALARIA AMONG CHILDREN WITH SICKLE CELL DISEASE IN EASTERN UGANDA.
REFNo: HS5714ES

i) To determine the effect of host RBC polymorphisms on the risk and severity of malaria.
ii) To determine the Geospatio-temporal distribution of the malaria-sickle cell disease syndemic in Uganda.
iii) To determine the clinical spectrum of severe malaria among children with SCA in eastern Uganda.

Uganda 2025-04-01 17:21:57 2028-04-01 Medical and Health Sciences Non-Clinical Trial Degree Award
ERICK SSEGUJJA
ID: UNCST-2021-R012964
Partnerships for Stronger Knowledge Systems in Africa (KNOSA): Lessons from Uganda
REFNo: HS5716ES

Specifically, the implementation research has the following objectives;
1. To characterise the nature and functioning of the different components of the current national knowledge system, ??with a focus on the health sector.
2. To explore constraints and challenges affecting the capacity of Uganda’s national knowledge systems.
3. To document and assess the current interventions to strengthen the national knowledge system?
4. To explore opportunities for strengthening the capacity of the national knowledge system to advance evidence-informed decision making in Uganda’s health sector.

Uganda 2025-03-25 11:14:05 2028-03-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Moses Galiwango
ID: UNCST-2024-R015239
INTEGRATED FEMALE SEXUALLY TRANSMITTED INFECTION TESTING FOR HIV EPIDEMIC CONTROL THROUGH PREP (IN-STEP)
REFNo: HS5715ES

a) To conduct an individually randomized effectiveness implementation trial of SRST plus cSTI testing to increase PrEP use among African women at high HIV risk.
b) To perform a mixed-methods, implementation science evaluation of female cSTI testing for improving PrEP use for HIV prevention.
c) To determine the most efficient, population-level female cSTI testing strategies to reduce HIV incidence in African settings.

Uganda 2025-03-25 11:13:20 2028-03-25 Medical and Health Sciences Clinical Trial Non-degree Award
Prudence Beinamaryo
ID: UNCST-2023-R007239
Developing a robust interdisciplinary-informed WASH framework for the prevention and elimination of the wicked public-health problem of schistosomiasis (WickedSchisto)
REFNo: HS5707ES

I. What are the true health, economic and societal impacts of schistosomiasis?
a) Characterise what quality of life means to individuals living in Schistosoma endemic areas in Cameroon and Uganda, and how this is affected by infections, WASH access, environmental, spatial, social and other determinants.
b) Measure the diverse impact of schistosomiasis on individual’s and household’s quality of life.
c) Quantify the economic costs associated with schistosomiasis to individuals and society.
d) Develop and validate a field-suitable morbidity marker for mapping and monitoring disease resolution.
II. What are the most cost-effective combinations of WASH and MDA interventions?
a) Test the hypothesis that MDA refusal, due to fear of side effects, is linked with latrine access.
b) Characterise relative contributions of existing WASH on reducing reinfection post MDA: risk to self.
c) Quantify environmental force-of-infection and the impact of ‘risk to self’ and ‘risk to
Uganda 2025-03-25 11:11:44 2028-03-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Riley Derby Nicholas
ID: UNCST-2025-R017680
Impacts of early social life on social and physical development in mountain gorillas
REFNo: NS946ES

Study social and physical change in immature mountain gorillas in Bwindi Impenetrable National Park, in collaboration with Bwindi Gorilla Project, through combining behavioral, hormonal, and non-invasive growth measures
USA 2025-03-25 11:02:11 2028-03-25 Natural Sciences Non-Clinical Trial Non-degree Award
Erika Sininärhi
ID: UNCST-2025-R017295
Physiological correlates of variation in personality traits in the banded mongoose Mungos mungo
REFNo: NS942ES

1) To determine the relationship between social rank, prenatal androgen exposure, and personality. 2) To investigate whether individual differences in facial thermal patterns are connected to personality, behaviour and stress reactivity.
Finland 2025-03-25 11:01:27 2028-03-25 Natural Sciences Non-Clinical Trial Degree Award
David Hayman T. S.
ID: UNCST-2023-R006403
One Health, multiple factors: an interdisciplinary investigation of emerging infectious disease
REFNo: NS924ES

Infectious diseases significantly impact global health, affecting both humans and animals. Zoonotic diseases, which are transmitted between animals and humans, pose particular risks in regions with high human-wildlife interaction. One such region is Uganda, specifically around Bwindi Impenetrable National Park (BINP), where communities live in close proximity to domestic and wild animals.

The objectives of this research are to:

Identify and quantify zoonotic pathogens in fecal samples from various animal species.

Assess pathogen prevalence across different species.

Analyze microbial community structures and antimicrobial resistance genes.
New Zealand 2025-03-25 11:00:19 2028-03-25 Natural Sciences Non-Clinical Trial Non-degree Award
Joan Mutyoba Nankya
ID: UNCST-2021-R010992
Using patient journey mapping approach to understand and improve post-abortion care within routine health care services
REFNo: HS4137ES


General objective

The general objective of this study is to use a journey mapping approach to understand client experiences as they navigate abortion services, and gaps in services, in order to improve PAC service delivery, client experiences and outcomes within the health care system.
Specific objectives

The specific objectives of the journey mapping approach include:

1. To document client experiences at different stages of post-abortion care-seeking.
2. To understand the current service provision processes for clients seeking post-abortion care services and identify gaps and unmet needs in these services.
3. To evaluate comprehensiveness of care and identify interventions to improve care.
4. To compare patient experiences with established standards of care

The specific objectives of the survey include:
1. To characterize the type and range of contraceptive and abortion-care services available for women who seek care at health facilities.
2. To determine whether women, including young women, receive comprehensive counseling on choices related to manual vacuum aspiration (MVA), medical abortion (MA) and contraception and which factors are related to receipt of such counselling.
3. To determine whether family planning and abortion services are provided with respect and compassion.

Uganda 2025-03-25 10:56:04 2028-03-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Karen Bailey M.
ID: UNCST-2024-R003544
Understanding invisible socio-environmental systems through pesticides across human-wildlife interactions
REFNo: SS3710ES

To model simulations of the interactions within the SES, illustrating the feedback mechanisms between pesticide use, environmental changes, and human-wildlife well-being,To quantify pesticide exposure and associated health outcomes in humans and wildlife, with a focus on spatial and temporal trends,To assess socio-economic and environmental factors influencing farmers\' decisions regarding pesticide use,To investigate the socio-environmental drivers and molecular-level impacts of pesticide use in a tropical forest-agricultural mosaic and develop strategies that balance agricultural productivity with biodiversity conservation among communities around the Kibale National Park ,
USA 2025-03-25 10:53:06 2028-03-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
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