Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Stevens Bechange
ID: UNCST-2022-R009190
Livelihood and Employment Sustainability among Youth with Disabilities in Rural Uganda
REFNo: SS2038ES

This research documenting young people’s everyday livelihood experiences over an extended period will be exploratory, but several theoretical concepts (e.g., livelihood framework, quality of life, sense of economic empowerment) inform the research questions and variables or processes to be explored. Changes to individual circumstances or experiences will not be evaluated through use of a control group, but by longitudinal analysis based on retrospective techniques (e.g., work history and livelihood narrative) and prospective techniques over the 16-month study: (a) What socio-economic changes have been experienced by youth with disabilities since enrolment into the economic empowerment programme? • Has participation in the programme enabled the young men and women with disability to change or undertake paid work activities and livelihood strategies? • Has participation in the programme led to changes in the participant’s and family’s intra-household relationships and social networks? • Has participation in the programme enabled the participant to improve and invest in asset portfolios and their management? (b) What is the participant’s experience of peer research – either as the researched or the researcher? What factors in their daily lives influence their ability to engage in, co-create and co-deliver research with professional researchers? (c) How does participation in an economic empowerment programme affect young people’s outlook and strategies for the future in this setting? (d) To what extent is participation in an economic empowerment programme and improved employability prospects modifying stigma as it manifests in the participant’s social relationships? (e) From the above, how does participation in an economic empowerment programme affect the participant’s quality of life and sense of well-being?
Uganda 2023-10-10 15:30:38 2026-10-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Michael Kizito
ID:
Influence of social media and smart phone use on academic performance of university students
REFNo: SIR239ES

The main objective of this study is to investigate the influence of social media and smartphone usage on the academic performance of university students in Makerere University CoCIS.
Uganda 2023-10-10 15:29:12 2026-10-10 Engineering and Technology Non-Clinical Trial Non-degree Award
Anxious   Niwaha Jackson.
ID: UNCST-2023-R008010
Investigating the relationship between poor nutrition in early-life and markers of metabolic disorders in young people within the General Population Cohort in rural Uganda (The DEPROMACE study)
REFNo: HS2757ES

The overall aim of this study is to investigate children exposed to undernutrition (low-birth weight and stunting) for a reduction in pancreas and kidney function capacity by assessing their glucose changes following an oral glucose test and BP response to changes in dietary salt intake The primary study objectives are: 1. To identify children in the general population who have evidence of early childhood malnutrition.
2. To identify the social and cultural factors associated with early childhood nutrition within this population.
3. To compare the relative glucose area under the curve (AUC) comparing subjects who have history of low birth weight and undernutrition in early-life to those with normal birth weight, normal weight and height below 5 years.
4. To compare blood pressure changes following salt-challenge tests between subjects with history of low birth weight and undernutrition in early-life and those with normal birth weight, normal weight and height below 5 years.

Uganda 2023-10-10 15:21:49 2026-10-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hilbert Mendoza
ID:
Urban green spaces as a potential climate change adaptation strategy for climate-sensitive health outcomes: a case study of Kampala, Uganda RefNo:SPH-2023-389
REFNo: HS3041ES

In this study, generally, we will investigate the association between residential surrounding greenness and climate-sensitive health outcomes among adult urban residents of Kampala, Uganda. More specifically, we will assess the following: 1. The association between residential surrounding greenness and hypertension among urban residents of Kampala 2. The association between residential surrounding greenness and depressive disorder among urban residents of Kampala 3. The association between residential surrounding greenness and anxiety disorder among urban residents of Kampala 4. The mediating role of outdoor air pollution, physical activity, and outdoor temperature in the association between residential surrounding greenness and climate-sensitive health outcomes (hypertension, depressive and anxiety disorders).
Uganda 2023-10-04 22:28:33 2026-10-04 Medical and Health Sciences Non-Clinical Trial Degree Award
Finagnon  Fassinou Toyi Kevin
ID: UNCST-2023-R008387
IMPROVING THE CARBOHYDRATE QUALITY OF POLISHED MAIZE FLOUR USING HEAT-MOISTURE TREATMENT
REFNo: A338ES

The main objective of the present study is to improve the resistance starch content of polished maize flour using heat moisture treatment. Specifically, this study intended (1)To characterize carbohydrate quality and internal factors affecting the starch digestibility of polished maize flour (2)To optimize the application condition of heat moisture treatment to improve the resistance starch content in polished maize flour (3)To investigate the effect of heat moisture treatment on aflatoxin detoxification of maize grain and functional proprieties of polished maize flour (4)To evaluate the effect of heat moisture treatment on in vivo glycemic response and sensory acceptability of polished maize dough.
Benin 2023-10-04 22:26:53 2026-10-04 Agricultural Sciences Non-Clinical Trial Degree Award
Mbogo David
ID: UNCST-2023-R007864
Optimization of Matooke Starch for application as a Novel Pharmaceutical excipient
REFNo: NS631ES

General objective: To determine the quality attributes of modified Matooke starch as a pharmaceutical excipient Specific objectives: i) To extract Matooke starch, through preparation, isolation and purification. ii) To modify Matooke starch, by annealing, extrusion and substitution. iii) To analyze Modified Matooke Starch for its physicochemical and functional properties as a novel pharmaceutical excipient.
Uganda 2023-10-04 22:04:44 2026-10-04 Natural Sciences Non-Clinical Trial Degree Award
willy waninga
ID:
THE INCORPORATION OF ICT AND GENDER IN THE TEACHING OF PHYSICS EDUCATION IN TEACHER TRAINING INSTITUTIONS IN EASTERN UGANDA
REFNo: SS1891ES

1. To investigate physics lectures’ ICT competence levels (Technological content knowledge) in TTIs in Eastern Uganda.
2. To find out ICT application or tools used by lecturers in teaching Physics Education in TTIs in Eastern Uganda.
3. To examine the different factors which impede the lecturer’s use of ICT in the teaching of physics Education in TTIs in Eastern Uganda.
4. To find out ICT competences possessed by physics student teachers by gender in TTIs in Eastern Uganda.
5. To compare the ability of students in using ICT to enhance their achievement in physics by gender in TTIs in Eastern Uganda.

Uganda 2023-10-04 21:56:08 2026-10-04 Social Science and Humanities Non-Clinical Trial Degree Award
Pius Lutaaya
ID:
AN EPIDEMIOLOGICAL SURVEILLANCE STUDY ON ANTI-MICROBIAL RESISTANCE TESTING FOR LEPROSY IN UGANDA
REFNo: HS3014ES

1. To identify the optimal laboratory diagnostic method for AMR for leprosy at NTRL Uganda
2. To estimate the burden of resistance among leprosy (new cases and relapses, treatment failures and patients who live in villages where PEP has been distributed

Uganda 2023-10-04 21:53:28 2026-10-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joshua Epuitai
ID: UNCST-2022-R009519
Assessment of Utilization of Clinical Simulation in Teaching and Learning among undergraduate students in Busitema University and Lira University
REFNo: HS3027ES

4. To determine utilization of simulation in the teaching among undergraduate students in Lira and Busitema University,3. To explore experiences of conducting simulation in an inter-professional health training among undergraduate students in Lira and Busitema University ,2. To investigate facilitators, and barriers to the use of simulation among faculty and clinical preceptors in Lira and Busitema University,1. To determine the experiences, perceptions, and acceptability regarding the use of simulation among undergraduate students in Lira and Busitema University,
Uganda 2023-10-04 13:55:20 2026-10-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Letizia Atim Maria
ID:
Comparison of patient profiles between health professionals and non-health professionals at Butabika national referral Hospital; a retrospective chart review.
REFNo: HS3062ES

1. To describe the sociodemographic profile of health professionals admitted to Butabika National Referral Hospital as compared to non-health professionals. 2.To describe the clinical profile of health professionals admitted to Butabika national referral hospital as compared to non-health professionals.
Uganda 2023-10-04 13:50:27 2026-10-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jimmy  Alemiga
ID: UNCST-2023-R007605
Intangible Resources and Competitive Advantage in Indigenous Family Owned Businesses in Uganda
REFNo: SS1945ES

To explain how post 1st indigenous FOBs conceptualize the notion of competitive advantage Kampala City Council Authority.,To explore how post 1st indigenous FOBs in Kampala City Council Authority strategically position themselves to attain competitive advantage.,To analyze the influence of organizational culture on competitive advantage for post 1st indigenous FOBs in Kampala City Council Authority. ,To access the effect of human resource practices on competitive advantage for post 1st indigenous FOBs in in Kampala City Council Authority. ,To examine the influence of corporate reputation on competitive advantage for post 1st indigenous FOBs in Kampala City Council Authority. ,The purpose of this study is to examine the contribution of intangible resources and competitive advantage for post 1st generation indigenous FOBs in Kampala City Council Authority. The focus of the study is CA measured by cost leadership, differentiation, and focus strategy (Porter, 1980). The intent is to provide both theoretical and empirical evidence in the RBV stream that exists in as far as understanding the specific contribution of IRs in achieving CA. ,
Uganda 2023-10-04 13:48:55 2026-10-04 Social Science and Humanities Non-Clinical Trial Degree Award
Prudence Beinamaryo
ID: UNCST-2023-R007239
Efficacy of the combination ivermectin and albendazole vs albendazole alone in school-aged children infected with Trichuris trichiura: a randomized controlled trial
REFNo: HS3160ES

To evaluate the safety and tolerability of the ,To determine the CRs and ERRs of the study drugs (i.e. albendazole alone, albendazole-ivermectin) against Ascaris lumbricoides and hookworm in co-infected participants.,To determine the egg reduction rates (ERRs) of ivermectin/albendazole combination therapy compared to albendazole monotherapy against T. trichiura,To demonstrate that co-administered ivermectin (200 µg/kg) plus albendazole (400 mg) is superior to albendazole (400 mg) monotherapy in terms of CRs against T. trichiura infections assessed by Kato-Katz at 14-21 days post-treatment in individuals aged 6-12 years.,
Uganda 2023-10-04 13:42:09 2026-10-04 Medical and Health Sciences Clinical Trial Non-degree Award
Samuel Gonahasa
ID: UNCST-2023-R007310
Impact of long-lasting insecticidal nets (LLINs) treated with chlorfenapyr plus pyrethroid vs LLINs treated with piperonyl butoxide plus pyrethroid on malaria incidence in Uganda: a cluster-randomised trial
REFNo: HS3185ES


To evaluate the impact of chlorfenapyr-pyrethroid LLINs (PermaNet Dual), as compared to PBO-pyrethroid LLINs (PermaNet 3.0), on malaria incidence in Uganda. We will test the hypothesis that malaria incidence will be lower in intervention clusters (randomised to receive chlorfenapyr-pyrethroid LLINs) than in control clusters (randomised to receive PBO-pyrethroid LLINs).

Uganda 2023-10-04 13:38:57 2026-10-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Asmaa Emara Elsayed
ID:
Instructional Supervision and Students’ Grades at Completion; The Moderating Effect Of Academic Staff Job Satisfaction In Private And Public Universities, Kampala- Uganda UCUREC-2023-535
REFNo: SS1902ES

iv. To establish whether academic staff job satisfaction moderates the relationship between instructional supervision and students’ grades at completion in private and public universities in Kampala, Uganda.,iii. To assess the relationship between academic staff job satisfaction and students’ grades at completion in private and public universities, Kampala Uganda.,ii. To find out the relationship between instructional supervision and academic staff job satisfaction in private and public universities in Kampala, Uganda.,i. To determine the relationship between instructional supervision and students’ grades at completion in private and public universities in Kampala, Uganda,
Egypt 2023-10-03 19:09:00 2026-10-03 Social Science and Humanities Non-Clinical Trial Degree Award
David Henning Johannes
ID:
The economic impact of tax compliance interventions
REFNo: SS1699ES

This study focuses on three problems.

The first problem is documenting what costs companies incur when receiving different compliance actions. While anecdotal evidence suggests these could be substantial, there has, to the best of our knowledge, not been no systematic survey documenting the costs incurred by companies.

The second problem is estimating where to optimally target what compliance actions bearing in mind the costs to companies and spillover effects. This involves three steps, 1) estimate the impact of compliance actions on the targeted company, 2) estimate the spillover effects of these compliance actions on the targeted company’s’ trading partners, 3) conduct heterogeneity analyses to understand which groups of taxpayer experience the highest/lowest impact. Gaining a good understanding of this problem will help increase the benefit-cost ratio of enforcement interventions.

Finally, if we find that firms change their tax filings after receiving a compliance intervention, we will seek to understand what drives this change in behavior. Theoretically, the mechanism behind a firms’ response is unclear. Firms could respond because they update their beliefs about the likelihood of being caught for tax evasion, because they realize that being caught is costlier, or because the intervention imposes a financial burden on the company mechanically change the amount of taxes they pay.

Germany 2023-10-02 16:24:09 2026-10-02 Social Science and Humanities Non-Clinical Trial Degree Award
Jennifer Moore Joy
ID:
'Good periods': Investigating how menstruation is constructed as a site of intervention
REFNo: SS1684ES

Investigate how menstruation is produced as a development concern at different sites by different stakeholders in the international development apparatus.

Examine how my interlocutors’ (NGO workers) conceptualize menstruation as a development problem and how they defend it.

Examine how the subjectivities/embodied experiences of beneficiaries of interventions relate to the framing of menstruation as a development concern

Determine what effects are produced by my interlocutors conceptualisations of the problem of menstruation.

Examine what my interlocutors leave unproblematic in their conception(s) of menstruation as a problem.

Examine whether assumptions/premises underpinning the conception(s) of menstruation as a development problem at the global level shared by my interlocutors.

Investigate how NGO workers themselves problematize menstruation, specifically in relation to the biomedical problematization of menstruation in the global development agenda and the subjectivities of beneficiaries.

Determine how NGO workers broker/translate between different problem representations of menstruation including that of the global development agenda and those experienced by beneficiaries.

Examine what other framings of menstruation are beneficiaries subject to and how these impact their embodied experiences of menstruation.
UK 2023-10-02 16:10:32 2026-10-02 Social Science and Humanities Non-Clinical Trial Degree Award
Deborah Natumanya
ID:
Smartphone Application for detecting Pesticide residues found in edible parts of tomatoes, cabbages, carrots and green pepper vegetables.
REFNo: SIR206ES

(i) To develop a mobile app that takes bio components of tomatoes, cabbage, carrots, and green pepper
vegetables in-form of infrared images and detects the presence of chemical residues.
(ii) To test the accuracy of the App in finding and determining the chemical residue amounts found present in
tomatoes, green pepper, carrots and cabbage vegetables.
Uganda 2023-10-02 16:06:18 2026-10-02 Engineering and Technology Non-Clinical Trial Non-degree Award
Thomas Atunyo
ID:
INCIDENCE, RISK FACTORS AND OUTCOMES OF POST-ANAESTHETIC COMPLICATIONS: A PROSPECTIVE COHORT STUDY IN MULAGO NATIONAL REFERRAL HOSPITAL POST-ANAESTHESIA CARE UNIT Ref No: Mak-SOMREC-2023-585
REFNo: HS3115ES

3. To determine the outcomes of post-anaesthetic complications in MNRH PACU,2. To describe the risk factors for post-anaesthetic complications in MNRH PACU,1. To determine the incidence of post-anaesthetic complications in MNRH PACU,To determine the incidence, risk factors and outcomes of post-anaesthetic complications in MNRH PACU.,
Uganda 2023-10-02 16:03:08 2026-10-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Racheal Angom
ID: UNCST-2023-R007485
UPTAKE AND INTEGRATION OF THE NCCN HARMONIZED GUIDELINES FOR SUB-SAHARAN AFRICA: A SURVEY
REFNo: HS3042ES

3. To determine UCI clinicians’ attitudes about cancer treatment guidelines in general and NCCN-HG for SSA in particular.,2. To determine the proportion of clinicians at the UCI who use NCCN-HG for SSA,1. To determine the proportion of clinicians at the UCI who know about the NCCN-HG for SSA,To determine what proportion of clinicians at the UCI knows about the NCCN Harmonized Guidelines for sub Saharan Africa (NCCN-HG for SSA) whether they use them, their attitudes about cancer treatment guidelines in general and NCCN-HG for SSA in particular.,
Uganda 2023-10-02 16:01:42 2026-10-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Mayito
ID:
THE ROLE OF LEPTOSPIROSIS AND RICKETTSIOSIS IN ACUTE UNDIFFERENTIATED FEVER PATIENTS IN UGANDA – LEPTO SPIRIT STUDY
REFNo: HS3002ES

Primary objectives
1. To determine the prevalence of leptospirosis and rickettsiosis among fever patients in Uganda
2. To describe the risk factors associated with leptospirosis and rickettsiosis in Uganda
Secondary objectives
1. To validate and apply point-of-care diagnostics of leptospirosis and rickettsiosis along with reference tests
2. To identify the Leptospira and Rickettsia species circulating among AUF patients by qPCR, DNA barcoding, or whole-genome sequencing
Tertiary objectives
1. To store specimens for future diagnostic evaluation for causative agents of AUF.

Uganda 2023-10-02 15:57:52 2026-10-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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