David Meya Bisagaya
ID: UNCST-2019-R000837
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High Dose AMBISOME on a Fluconazole Backbone for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: A Phase 3 Randomised Controlled Non-Inferiority Trial
REFNo: HS213ES
Primary Objective:
To determine whether short-course high-dose L-AmB is as effective as 7-day amphotericin B deoxycholate-based treatment courses (current standard of care) in averting all-cause mortality in HIV-associated CM patients in a phase-III clinical endpoint trial.
Secondary Objectives:
1. To determine the EFA in both treatment arms.
2. To examine the proportions of patients in each arm with clinical and laboratory-defined grade III/IV adverse events; median % change from baseline in laboratory defined parameters, by treatment arm.
3. To determine health service costs by treatment arm.
4. To determine all-cause mortality within the first 2 and 4 weeks.
5. To determine whether short-course high-dose L-AmB is superior to 7-day amphotericin B-based treatment courses (current standard of care) in averting all-cause mortality.
6. To determine rates of cryptococcal relapse / IRIS within the first 10 weeks by treatment arm.
7. To determine rates of disability at 10 weeks by treatment arm.
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Uganda |
2018-07-26 |
2021-07-26 |
Medical and Health Sciences |
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Non-degree Award |
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David Meya Bisagaya
ID: UNCST-2019-R000837
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Operational Research for Cryptococcal Antigen Screening (ORCAS) of HIV Patients: Evaluation of clinical and immunological predictors of outcomes.
REFNo: HS214ES
To identify incidence and risk factors for meningitis or death in asymptomatic CrAg+ persons before 6-months.
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Uganda |
2018-07-26 |
2021-07-26 |
Medical and Health Sciences |
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Non-degree Award |
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Josephine Kayaga Nsubuga-Mugoa Kayaga
ID:
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Successful Strategies for Using Knowledge Management in Small- and Medium-Sized Enterprises (SMEs)
REFNo: SS228ES
The purpose of the research study is to explore strategies that some SMEs managers use to effectively integrate Knowledge Management (KM) into their business practices; with the objective that the research study will enable me to make a contribution to positive social change as the findings from this study may be helpful in expanding opportunities for employees to learn new skills and knowledge. Another contribution to positive social change may be the expansion of employment opportunities because, as SMEs integrate KM into their business practices, SMEs may become more successful, leading to the expansion of employment opportunities.
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Uganda |
2018-07-26 |
2021-07-26 |
Social Science and Humanities |
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Degree Award |
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Julia Dickson-Gomez
ID: UNCST-2019-R000775
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The Social Context of Substance Use and HIV Risk in Kampala City, Uganda
REFNo: SS227ES
To conduct formative research to assess drug use in individuals living in Kampala and the associated contextual factors (drug use sites, sexual and drug networks) that may contribute to HIV injection and sexual risk behaviors.
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USA |
2018-07-26 |
2021-07-26 |
Social Science and Humanities |
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Non-degree Award |
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Nando Lewis
ID:
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Why do people flee their homes for UNHCR refugee assistance in Eastern Africa?
REFNo: SS212ES
This project aims to better understand South Sudanese refugee decision making before leaving their homes and in selecting their destination. I aim to go beyond the conflict causes displacement explanation, to investigate what levels of conflict and how other factors such as food insecurity influence the decision to flee ones home. I am also interested in better understanding why some South Sudanese travel to Uganda, whilst others travel to Kenya.
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UK |
2018-07-24 |
2021-07-24 |
Social Science and Humanities |
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Degree Award |
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