Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Miriam  Amutuheire
ID: UNCST-2024-R001859
Home-based tourism businesses and destinaion sustainability in Kabale Municiplaity, Kabale District, Uganda.
REFNo: SS3399ES

i.To assess the effect of the home-based tourism business operations on destination sustainability in Kabale municipality, Kabale District, Uganda.    
ii. To determine the influence of home-based tourism businesses competitiveness on destination sustainability in Kabale municipality, Kabale District, Uganda.  
iii. To establish the influence of government policies, impart on home-based tourism businesses that affect destination sustainability in Kabale municipality, Kabale District, Uganda.  
Uganda 2025-01-31 7:38:46 2028-01-31 Social Science and Humanities Non-Clinical Trial Degree Award
Karugahe Wilber
ID: UNCST-2023-R005686
Effectiveness of Cognitive behaviour therapy for mental health problems among adult patients with type-II diabetes mellitus: a controlled study
REFNo: SS3413ES

a. To assess the effectiveness of CBT in treating mental health problems (psychological distress, depression, anxiety, quality of life, treatment adherence, hopelessness, pessimism) among adult patients with T2DM
b. To assess whether CBT affords a better control of glycaemia and the metabolic disturbances associated with T2DM.

Uganda 2025-01-31 7:37:29 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
Maternal immunization readiness network for the introduction of potential new maternal vaccines to prevent early childhood infectious diseases in Uganda
REFNo: HS5271ES

General objective:

To identify, characterize and support the platform, policy, and preparedness requirements for the introduction of potential new maternal vaccines to prevent infectious diseases in Uganda


Specific objectives:

1. To identify and implement approaches to assess health systems, facilities, and community readiness to introduce new maternal vaccines in Uganda
a. Identify and implement approaches to assess MI readiness for respiratory syncytial virus / Group B streptococcus vaccinations across the health system, including mapping key regulatory and financing requirements.
b. Map professional societies within the country and initiate country-based communities of practice for MI.
2. Generate and synthesize health economic evidence, in the Ugandan context, to support decision-making of respiratory syncytial virus / Group B streptococcus vaccination program adoption in low- and middle-income countries (LMICs).
3. Prospectively develop nationally tailored maternal vaccine demand strategies to support the uptake and sustained demand for existing and new maternal vaccines in Uganda.
4. Identify and effectively engage with diverse stakeholders, in a harmonized manner, to incorporate their views and expertise in the study’s outputs, to advance the maternal immunization readiness agenda in Uganda.

Uganda 2025-01-31 7:35:56 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Rukundo NSHAKIRA
ID: UNCST-2021-R012277
Improving School Management in a Low-Income Country: Experimental Evidence from Uganda
REFNo: SS3462ES

To evaluate the impact of the Inspect and Improve (I&I) program on student outcomes (learning, safeguarding, and inclusion) and school quality, focusing on both short-term and long-term effects.
Uganda 2025-01-31 7:32:19 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Moses Ochora
ID: UNCST-2021-R012659
RUNYA-PHIV: Rural Uganda Neurocognitive Youth Assessment with Perinatally acquired HIV
REFNo: HS5534ES

To explore the differences in NeuroScreen performance among adolescents aged 12-19 years with Perinatally acquired HIV in urban (Kampala) vs rural areas (Mbarara).,To adapt NeuroScreen to assess neurocognition among Runyankole-speaking adolescents aged 12-19 years with Perinatally Acquired HIV ,
Uganda 2025-01-31 7:31:16 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Samuel Kyobe
ID: UNCST-2019-R000108
DSpace – Ethical Implications of Pediatric EHR Use in Medical Research in Uganda and Botswana
REFNo: HS5301ES

1. Analyze the ELP issues raised by the use of pediatric EHR in medical research in Uganda and Botswana
2. Determine/analyze the implications of data linkage on participant consent and privacy
Uganda 2025-01-31 7:27:19 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Maleka
ID: UNCST-2024-R015301
Sex differences in alcohol consumption and its impact on vulnerability and susceptibility to develop dementia in rural Uganda.
REFNo: SS3477ES

1. To determine the patterns of alcohol consumption among men and women aged 60 years and above in Ibanda and Lira districts.
2. To assess the association between alcohol consumption and cognitive impairment among men and women in rural Uganda
3. To determine the socio-cultural factors that contribute to gender differences in the vulnerability to alcohol-related cognitive impairment in Ibanda and Lira districts.

Uganda 2025-01-31 7:24:38 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
john semuwemba
ID: UNCST-2022-R015225
Association between prenatal alcohol exposure and Cognitive and Behavioral impairments among primary school children aged 6 to 10 years in rural Rwampara and Lira districts.
REFNo: HS5331ES

General Objective.
To determine the prevalence of prenatal alcohol exposure and the association between prenatal alcohol exposure and cognitive and behavioral impairments among primary school children aged 6 to 10 years in rural Rwampara and Lira districts.
Specific Objectives.
1 To determine the prevalence of prenatal alcohol exposure in rural Rwampara and Lira districts.
2 To determine the prevalence of cognitive and behavioral impairments among primary school children aged 6 to 10 years in rural Rwampara and Lira districts.
3 To determine the association between prenatal alcohol exposure and cognitive and behavioral impairments among primary school children aged 6 to 10 years in rural Rwampara and Lira districts.

Uganda 2025-01-31 7:22:50 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Mukunya
ID: UNCST-2022-R010707
A phase III, randomized, open-label, clinical trial to evaluate the safety and efficacy of emollient therapy for very low birthweight infants (<1500g) in Uganda in promoting survival, health, growth and development compared to no emollient treatment
REFNo: HS5338ES

To evaluate the efficacy of emollient therapy with SSO – compared to standard care without use of emollients – among hospitalised very low birth weight (VLBW, <1500g) infants in Uganda on: the rate of in-hospital mortality, serious infections, hypothermia, growth, intraventricular haemorrhage, and skin condition; maternal depression and anxiety; maternal and neonatal interaction; infant growth and neurodevelopment at 12 month corrected age (chronological age reduced by the number of weeks born before 40 weeks of gestation); and infant mortality.
Uganda 2025-01-31 7:21:53 2028-01-31 Medical and Health Sciences Clinical Trial Non-degree Award
Adam Hewitt Smith
ID: UNCST-2019-R001658
Evidence based QUality Improvement for Prescribing Stewardship in ICU (EQUIPS-ICU): protocol for type III hybrid implementation-effectiveness study.
REFNo: HS5389ES

To evaluate the impact of a structured antimicrobial review on rates of antimicrobial density, redundancy and associated indicators of antimicrobial utilisation.,To determine whether a structured antimicrobial review can be implemented in LMIC ICUs,
UK 2025-01-31 7:20:18 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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