Samson Okello
ID: UNCST-2019-R001580
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Epidemiology of Coronary Artery Disease among People with HIV in Rural sub-Saharan Africa
REFNo: HS267ES
Our over-arching goals are to demonstrate the extent to which coronary artery disease (CAD) burden may be greater among PLWH in rural Uganda, to discern which risk factors are responsible for this greater burden, and to propose a risk score and promising intervention targets to improve the health of this population.
Aim 1: Determine whether CAD is more prevalent and severe among PLWH than HIV-uninfected comparators in rural Uganda. We will complete coronary CT angiography in 600 participants and compare the prevalence and severity of CAD between PLWH and HIV uninfected comparators, before and after adjustment for traditional risk factors
Aim 2: Determine the extent to which the association between HIV infection and CAD is modified by sex and region. Within our cohort, we will test for effect modification by sex
Aim 3: Identify regional correlates of CAD, and develop a risk prediction score for the presence of CAD among PLWH in rural sub-Saharan Africa. We will collect data on traditional (e.g. age, smoking, diabetes), HIV-specific (e.g. macrophage activation, CD4 count, ART history), and region-specific factors (e.g. biomass exposure, K:T ratio, tuberculosis infection). In Aim 3a we will include traditional, HIV-specific and regional risk factors in models to identify correlates of CAD. In Aim 3b, we will propose a simplified risk score to identify PLWH with CAD.
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Uganda |
2019-01-29 |
2022-01-29 |
Medical and Health Sciences |
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Non-degree Award |
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Rachael MacLeod
ID:
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A prospective observational study of intraventricular haemorrhage (IVH) in a neonatal cohort in Uganda: The IVHU Study.
REFNo: HS299ES
Overall objective
To study the proportion of low birth weight (LBW) babies affected by IVH and to assess the severity of and risk factors for IVH and outcomes after IVH at Mbale Regional Referral Hospital in eastern Uganda over a 6-month period.
Specific objectives
In LBW neonates in a Ugandan population:
• Describe the proportion of babies affected by IVH.
• Describe the timing and severity of IVH.
• Describe the incidence of complications including ventriculomegaly and cerebellar involvement, as well as other pathologies such as periventricular white matter changes with and without cystic change (PVL).
• Determine the neonatal morbidities and neonatal mortality associated with IVH.
• Describe risk factors associated with IVH.
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UK |
2019-01-22 |
2022-01-22 |
Medical and Health Sciences |
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Non-degree Award |
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Timothy Wakabi Waiswa
ID:
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LINKAGE BETWEEN SCHISTOSOMA MANSONI INFECTION IN BABOONS AND HUMANS WITHIN FISHING VILLAGES OF KASESE AND RUBIRIZI DISTRICTS IN QUEEN ELIZABETH NATIONAL PARK
REFNo: HS293ES
i. establish prevalence of S. mansoni in baboons and humans living in the fishing villages and factors associated with the infection
ii. assess the knowledge and perception of people living in fishing villages in and around QENP on transmission of zoonotic Schistosomiasis
iii. determine the geospatial and genetic relationship between S. mansoni in baboons and humans in fishing villages in and around QENP
iv. assess feasibility of stakeholder-identified interventions for addressing Schistosomiasis within the fishing villages
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Uganda |
2019-01-22 |
2022-01-22 |
Medical and Health Sciences |
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Degree Award |
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Ivan Kimuli Ronald
ID: UNCST-2019-R000577
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Viral load monitoring among HIV infected patients at Mulago Hospital: Perceived barriers and facilitators
REFNo: HS261ES
1. To describe the viral load cascade at the HIV clinic of Mulago National referral hospital
2. To explore the barriers to and facilitators of viral load monitoring among HIV-infected adults at Mulago Hospital
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Uganda |
2019-01-15 |
2022-01-15 |
Medical and Health Sciences |
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Non-degree Award |
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Florence Brisset-Foucault
ID:
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Registering and Identifying People in Uganda A Historical Approach
REFNo: SS210ES
Today, norms and practices of biometric identification are objects of global fascination, curiosity, anxiety or scrutiny. Yet, in the case of Africa, identification documents have hardly been central to scholarship. In order to fill this important gap, this study proposes to focus on the history of official/administrative documents of identification in Uganda, as objects of governmentality (Foucault, 2004). A great variety of identification documentation will be included, as empirical objects of study: birth certificates, voters’ cards, introduction letters by Local councils, party-membership cards, as well as other forms of nominative documentation such as land certificates and drivers’ licenses. The idea is that the daily uses of these objects and the popular representations attached to them will inform us on the parameters of public action, ordinary social life, the imagination of identities and civic cultures. By better understanding Ugandans' previous experiences of identification, it is expected that this research will inform best practices in terms of the documentation and verification of identities, and of the implication of these processes on the State and on society.
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France |
2019-01-15 |
2022-01-15 |
Social Science and Humanities |
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Non-degree Award |
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