Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Fred Kigozi
ID: UNCST-2025-R021423
Postprandial effect of isocaloric challenge meals enriched with indigenous fruits and vegetables on glucose metabolism in individuals with type 2 diabetes in Wakiso District, Uganda.
REFNo: HS7347ES

General Objective To evaluate the postprandial effect of isocaloric challenge meals enriched with indigenous fruits and vegetables on glucose metabolism among people living with type 2 diabetes in Wakiso district, Uganda. Specific Objectives 1.To assess the acute postprandial effects of isocaloric challenge meals enriched with indigenous fruits and vegetables on incremental area under the curve (iAUC) blood glucose levels. 2.To assess the acute postprandial effects of isocaloric challenge meals enriched with indigenous fruits and vegetables on iAUC blood triglyceride levels.
Uganda 2026-04-20 10:47:24 2029-04-20 Medical and Health Sciences Clinical Trial Degree Award
Milton Ayoki
ID: UNCST-2026-R024563
From job displacement to economic resilience: Mapping the net impact of AI on formal and informal employment across three African economies
REFNo: SS5147ES

The overall objective of this study is to generate rigorous, gender-disaggregated, intersectional evidence on the net socio-economic impacts of AI on formal and informal employment in Uganda, Kenya, and South Africa, and translate this evidence into rights-based, African-led policy frameworks that ensure AI transitions are inclusive, safe, and aligned with sustainable development. Specific objectives (i) To measure the causal effect of firm-level AI adoption on net employment task recomposition, earnings volatility, and household poverty risk, disaggregated by gender, age, disability, geography, and formality status. Using a sequentially integrated design—linking 1,200 firms’ AI Intensity Index to 4,500 workers’ diary panel and administrative tax records—we will identify which demographic groups face displacement versus augmentation, and trace micro-to-macro transmission channels affecting social-protection demand. (ii) To identify, test, and refine policy levers—portable social protection benefits, mandatory algorithmic fairness audits, and gender-responsive re-skilling subsidies—that enhance economic resilience for vulnerable workers, particularly women, youth, and persons with disabilities. Through a participatory GEDI Lab (co-chaired with trade unions, women’s networks, and PWD advocates) with veto power over sampling, instruments, and recommendations, we will validate rights-based policy scenarios via a regulatory sandbox covering 20 digital-labour platforms. This ensures policies are not technocratic but reflect lived realities and African priorities, directly minimizing AI’s potential to exacerbate gender inequalities and human rights violations. (iii) To strengthen Africa’s AI-labour research ecosystem by mentoring eight African PhD students (?60% women, ?20% PWDs) through a triadic supervision model, and creating an open-source Continental Methodology Toolkit (AI Intensity Index calculator, AfroXLMR models, intersectional DiD estimators) for continent-wide replication. Outputs will be embedded in national AI strategies, ESG disclosure rules, and a COMESA Model Law on Algorithmic Labour Practices, ensuring sustainability beyond the project’s 36-month timeline and transforming global AI-labour debates from models that ignore Africa into African-led evidence that guides the continent’s digital future.
Uganda 2026-04-20 10:43:58 2029-04-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Emmanuel Wegoye
ID: UNCST-2024-R003214
Neurocognitive Outcomes and Changes in Brain and Cerebral Spinal Fluid (CSF) Volume after Treatment of Post-Infectious Hydrocephalus (PIH) in Ugandan Infants by Shunting versus Endoscopic Third Ventriculostomy/Choroid Plexus Cauterization (ETV/CPC)
REFNo: HS7254ES

We propose to: 1) Develop and empower CURE Children’s Hospital of Uganda as a unique hydrocephalus research center in the developing world 2) Test the hypothesis that ETV/CPC is superior to shunt-dependence in regard to treatment failure at 10 years; 3) Determine whether our initial finding of neurodevelopmental non-inferiority for ETV/CPC at 12 months is durable to the critical time of 10-years follow up; 4) Determine whether our initial finding of non-inferiority in brain growth for ETV/CPC at 12 months holds true at 10-years of follow up
Uganda 2026-04-15 22:23:51 2029-04-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Innocent Mwaka
ID: UNCST-2026-R023653
Action Research for the Gender for Development Uganda (G4DU) Programme
REFNo: SS4991ES

3. STUDY CONTEXT AND OBJECTIVES
Given the critical role of UNICEF in addressing gender imbalances in education, this multiyear action research aims at generating actionable evidence and fostering continuous learning for the enhancement of the G4DU Program’s financial support models and AEP. This iterative research will serve as a critical feedback loop, informing UNICEF's adaptive programming and policy advocacy efforts. The research will target students, headteachers, parents and district education departments. The study will be conducted over a period of 2-3 months annually , to allow for implementation of the intervention and observation of its effects. Being ongoing research, it will focus on the implementation phase of the programme from 2025-2028. The research will be conducted in four of the seven districts, namely: Yumbe, Adjumani, Lamwo, and Kitgum, focusing on selected schools and households .
Objectives of the action research:
1. To explore the effectiveness of newly developed and tested models of:
? Performance-based school grants for girls’ retention and completion of primary education.
? Cash transfer to households aiming at adolescent transitioning to and retention in secondary education.

2. To assess the effectiveness of the AEP model targeting out-of-school adolescents towards improving alternative access, accelerated pathways to primary education and transition into formal schools (primary and secondary schools).
3. To assess the relevance, efficiency, and sustainability of G4DU interventions in reducing barriers to education for vulnerable adolescent girls.
4. Determine the effect of school-level planning, local government capacity strengthening and community engagement, towards improving participation, retention and transition of girls.
5. Identify lessons learned from the implementation of financial support models and complementary activities and provide recommendations for programme adaptation and policy influencing.

The insights gained from these objectives will provide UNICEF and its partners with a robust evidence base to refine existing interventions, scale up successful approaches, and advocate for policies that institutionalise effective strategies for inclusive education in Uganda.

Uganda 2026-04-15 21:38:10 2029-04-15 Social Science and Humanities Non-Clinical Trial Non-degree Award
Michael Timuzigu Kamugisha
ID:
Employability among University Graduates in Uganda
REFNo: SS5079ES

To examine the relationship between entrepreneurial alertness and employability. To establish the relationship between lifelong learning and employability. To investigate the relationship between entrepreneurial alertness and career adaptability. To establish the relationship between lifelong learning and career adaptability. To examine the relationship between career adaptability and employability. To investigate the mediating role of career adaptability in the relationship between entrepreneurial alertness and employability. To examine the mediation role of career adaptability in the relationship between lifelong learning and employability.
Uganda 2026-04-14 16:50:46 2029-04-14 Social Science and Humanities Non-Clinical Trial Degree Award
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