Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
UBUMWE 2.0 Integrating Arts for Education and Psychosocial Support with Children & Youth affected by Displacement in Uganda
REFNo: SS3567ES

1. To document how the Ubumwe curriculum influenced the roles and responsibilities of the teachers;
2. To identify additional teacher professional development opportunities that teachers feel are needed to be successful in teaching the Arts;
3. To explore the ways in which the art curriculum impacted Learners’ academic and psychosocial development;
4. To assess overall feasibility, acceptability, strengths and limitations of the Ubumwe curriculum for teachers.

Uganda 2025-02-07 17:43:07 2028-02-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Benard Nsubuga
ID: UNCST-2024-R002324
Factors influencing the availability and use of Electronic Medical Records Systems in Public Health Facilities in Uganda: A landscape assessment
REFNo: HS5379ES

i. Assess the extent of EMR adoption in public health facilities.
ii. Identify the types of EMR systems currently in use.
iii. Evaluate the functionality and integration of existing EMR systems.
iv. Understand the challenges and barriers to effective implementation of EMR integration.
v. Identify the factors influencing the use and adoption of EMR systems in public health facilities.
vi. Provide recommendations for enhancing EMR adoption and utilization.

Uganda 2025-02-07 17:42:08 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Prossy Bibangambah Kyasimire
ID: UNCST-2024-R002215
Pericoronary Adipose Tissue, Inflammation, and Subclinical Coronary Artery Disease in People with HIV in Uganda
REFNo: HS5418ES

Aim 1: Perform CCTA -based segmentation of PCAT (1a) and compare the density between PWH and PWOH (1b) in Uganda.
Aim 2: Extract PCAT radiomics features (2a) and compare differences in PCAT radiomics signatures between PWH and PWOH (2b) in Uganda.
Aim 3: Determine whether the PCAT density (from Aim 1) or radiomics signatures (from Aim 2) improve the performance of cardiovascular risk prediction in Uganda.
Uganda 2025-02-07 17:38:35 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
Bone Health in Older Ugandan Women with and without HIV
REFNo: HS5455ES

To examine bone mineral density (BMD) and body composition in older (peri-menopausal and postmenopausal) African women who are living with HIV and taking antiretroviral therapy (ART) drugs compared to women representing similar age and background characteristics who are HIV-negative.
Uganda 2025-02-07 17:30:13 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jennifer Serwanga
ID: UNCST-2024-R002056
Universal Protocol for Standardizing emerging Assays and Advancing vaccine Immunogenicity Assessments for Emerging and Re-emerging viral Threats through UVRI’S Partnership with the coalition for Epidemic Preparedness Innovations (CEPI)’s Centralized Clinical Laboratory Network (CLN).
REFNo: HS5330ES

To standardize and accelerate the evaluation of vaccine candidates against CEPI priority diseases, including Ebola, Marburg, Lassa, Nipah, Rift Valley Fever, SARS-CoV-2, MPOX and unidentified emerging threats, by leveraging UVRI's infrastructure and expertise.

To contribute to accelerated global vaccine development and licensure by ensuring rapid, accurate, and consistent data generation, while enhancing regional outbreak preparedness through technology transfer and capacity building.
Uganda 2025-02-04 8:15:09 2028-02-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald  Bahati
ID: UNCST-2023-R007024
NAVIGATING MENTAL HEALTH IN SCHOOLS PROJECT: EDUCATORS’ MENTAL HEALTH LITERACY CONCERNING ANXIETY, DEPRESSION AND NON-SUICIDAL SELF INJURY
REFNo: HS5381ES

To ascertain the educators’ confidence in providing help to affected school aged adolescents in selected schools in southwestern Uganda.,3. To assess educators’ level of mental health literacy about non-suicidal self-injury among school aged adolescents in selected schools in southwestern Uganda.,2. To assess educators’ level of mental health literacy about depression among school aged adolescents in selected schools in southwestern Uganda,1. To assess educators’ level of mental health literacy about anxiety among school aged adolescents in selected schools in southwestern Uganda,To assess educator’s mental health literacy about anxiety, depression and non-suicidal self-injury and their confidence in providing help to affected school aged adolescents in selected schools in southwestern Uganda.,
Uganda 2025-01-31 8:00:54 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Shevin  Jacob Thomas
ID: UNCST-2022-R010715
The Sub-Saharan Africa ConsorTium for the Advancement of Innovative Research and Care in Sepsis (STAIRS) Cohort Study: A prospective multi-country network cohort of hospitalized sepsis patients
REFNo: HS5205ES

1. Describe the cohort’s epidemiologic, sociodemographic, clinical and management characteristics and to identify risk factors for disease severity and outcomes. 2. Characterize etiologic (and antimicrobial resistance patterns when relevant) and host response profiles and to evaluate their potential associations with clinical presentation, disease severity and outcome. 3. Determine the performance characteristics of innovative sepsis diagnostic platforms for pathogen identification, host response profiling and risk stratification in comparison with diagnostic testing available for usual care (including blood culture and existing sepsis scores).
USA 2025-01-31 7:59:00 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sabiti Makara
ID: UNCST-2024-R003444
Crisis Emergencies, State Responses and ‘Windows’ of Corruption in Uganda
REFNo: SS3621ES

To implement bottom-up strategies for fighting corruption in emergency responses ,To examine the possibilities of grassroots actions and pressures that could have significant impacts on the fight against corruption,To establish the extent to which political considerations abate corruption with a focus on procurement and contracting during emergency crisis responses,To establish the gaps in regulatory frameworks that are opportunistically exploited by corrupt officials and their cronies to undermine anti-corruption efforts during emergency responses,Establish the actual costs of corruption and find out if the population is aware of its effects on public service delivery for the ordinary citizens,To examine the forms, practices, and patterns of corruption in emergency crisis responses in Uganda,Our main objective is to highlight and deepen our understanding of the extent which the risk of corruption intensifies during emergencies and to develop grassroots-based strategies to fight the vice.,
Uganda 2025-01-31 7:50:39 2028-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Vincent Ferrer Bukenya
ID: UNCST-2024-R004868
Examination of the relationships between refugee settlements and wood energy consumption: A case study of Bidibidi refugee settlement in northwest Uganda
REFNo: A527ES

This research will examine the relationships between refugee settlements and household access to sustainable wood energy. 1. To establish what forms the bulk of wood energy used by refugees and host communities in Bidibidi Refugee Settlement in North-Western Uganda. 2. To assess wood energy consumption patterns in refugee and host communities in relation to the right to energy in Bidibidi Refugee Settlement in North-Western Uganda. 3. To examine how the refugee response framework provides for household access to wood energy by refugees and host communities in Bidibidi Refugee Settlement in North-Western Uganda. 4. To determine the contribution of the refuge-host community relationships to households’ ability to sustainably access wood energy.
Uganda 2025-01-31 7:43:24 2028-01-31 Agricultural Sciences Non-Clinical Trial Degree Award
Ikuomola  Orire Emmanuel
ID: UNCST-2024-R003700
EFFECT OF DIFFERENT FRACTIONS OF BRASSICA OLERACEA (COLLARD GREENS) ETHANOL EXTRACT ON CIMETIDINE INDUCED REPRODUCTIVE TOXICITY IN MALE WISTAR RATS.
REFNo: HS5192ES

i. Identify and quantify the constituents of crude aqueous leaf extract and fractions of Uganda collard green plant using gas chromatography mass spectrometry (GCMS);
ii. Evaluate the impact of crude aqueous leaf extract and fractions of Uganda collard greens on the relative weights of the testes, epididymis and anterior pituitary gland compared to body weight in male Wistar rats with cimetidine-induced reproductive toxicity by [specific date] male Wistar rats;
iii. Assess the effects of crude aqueous leaf extract and fractions of Uganda collard greens on sperm parameters, including motility, morphology, viability, agglutination, and total sperm count in Wistar rats with cimetidine-induced reproductive toxicity;
iv. Analyze the effect of crude aqueous leaf extract and fractions of Uganda collard greens on serum levels of steroid androgens (LH, FSH, Testosterone and antioxidant enzyme activities (catalase, Malondialdehyde, superoxide dismutase) in male Wistar rats with cimetidine-induced reproductive toxicity in male Wistar rats;
v. Examine the histological changes in the testes, epididymis, and anterior pituitary gland in male Wistar rats with cimetidine-induced reproductive toxicity following treatment with crude aqueous leaf extract and fractions of Uganda collard greens in male Wistar rats.

Nigeria 2025-01-31 7:40:27 2028-01-31 Medical and Health Sciences Non-Clinical Trial Degree Award
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