Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ahmed Ddungu
ID: UNCST-2019-R000944
 THE ROLE OF TRANSFORMING GROWTH FACTOR BETA1 AS A PREDICTOR OF COPD IN A COHORT OF POST-TB HIV INFECTED PATIENTS IN UGANDA
REFNo: HS350ES

Primary objective:
• To assess for long term respiratory outcomes of TB in HIV infected adults by determining the burden of COPD and associated factors among members in the Study on Outcomes related to Tuberculosis and HIV drug concentrations’ (SOUTH) TB-HIV cohort at IDI at 0 and 24 months after enrolment in the TGFbeta study.
Secondary objectives
• To assess the association between serum TGFβ1 levels and burden of COPD amongst post-TB patients in the IDI ‘(SOUTH) TB-HIV cohort.
• To assess for an association between chest X-ray abnormalities at the end of TB treatment and COPD in post-TB HIV infected adults in the SOUTH study TB-HIV cohort at IDI.

 Uganda 2019-05-28 2022-05-28 Medical and Health Sciences Non-degree Award
Jackline Kampire
ID:
PHENOTYPIC AND GENETIC CHARACTERIZATION OF LOCAL PIG POPULATIONS IN SOUTH WESTERN AGRO-ECOLOGICAL ZONE (SWAEZ): THEIR DISTRIBUTION AND PORK QUALITY
REFNo: A44ES

1.To map the abundance and distribution of the local pig populations in SWAEZ.
2.To determine the phenotypic features of local pig breeds in SWAEZ.
3.To determine the genetic relationship between local pig populations and exotic breeds in SWAEZ.
4.To determine the pork quality of the local pig populations in SWAEZ.

 Uganda 2019-05-28 2022-05-28 Agricultural Sciences Degree Award
joseph  mwizerwa
ID:
Strengthening academic advancement for enrolled nurses: Developing a new program framework for enrolled nurses in Uganda.
REFNo: HS375ES

1.Explore experiences, aspirations and needs of ENs in Uganda with respect to advancing their nursing careers.
2.Identify the barriers and facilitators for academic advancement of ENs within Uganda.
3.Examine the suitability of Ugandan EN advancement programs in meeting EN education needs.
4.Critically examine international educational programs developed for ENs (or similar level nurses) career progression, to assess their applicability to the Ugandan context.
5.Develop a new academic advancement framework for ENs in Uganda and generate consensus for it.

 Uganda 2019-05-28 2022-05-28 Medical and Health Sciences Degree Award
Annabel  Morales-Smith
ID:
Assessing local attitudes towards tourism and conservation at Bwindi Impenetrable national park, Uganda
REFNo: SS302ES

This master’s research aims to investigate if park tourism can improve attitudes of residents involved in small-scale tourism enterprises towards protected area conservation, by delivering economic development; using Bwindi Impenetrable National Park (BINP) in Uganda as a case study.
The research objectives are:
• Measure expectations of residents involved in small-scale tourism enterprises based on their experiences of park tourism.
• Evaluating if recent interventions to enhance small-scale tourism enterprises have increased economic benefits from park tourism and if this has improved attitudes towards PA conservation.
• Assess the sustainability of these interventions.
The research hypothesis is: ‘Local attitudes towards protected area conservation improve when residents involved in small-scale tourism enterprises receive benefits from park tourism’.
And the research questions I will ask to test this hypothesis & achieve the aim of this project are:
• What expectations do residents involved in small-scale tourism enterprises have of park tourism?
• Do local attitudes towards protected area conservation improve when residents involved in small-scale tourism enterprises receive benefits from tourism?
• Do people feel they are sufficiently trained to continue without further interventions?

 UK 2019-05-21 2022-05-21 Social Science and Humanities Degree Award
Henry Kajumbula Mawerere
ID: UNCST-2019-R001531
 IDENTIFICATION OF VIRULENCE FACTORS, TRANSMISSION PATTERNS AND ANTIBIOTIC RESISTANCE MECHANISMS OF EAST AFRICAN Vibrio cholerae ISOLATES BY WHOLE GENOME SEQUENCING
REFNo: HS338ES

Aim: To obtain whole genome sequences (WGS) of Vibrio cholera O1 isolated in various parts of Uganda from 2014 to 2018 and use the data to determine the evolution, spread, antimicrobial resistance mechanisms and pathogenesis of the isolates

Specific objectives:
1. Determine patterns of spread of V.cholerae O1 in Uganda and within the East African region using WGS
2.Infer relatedness and evolution of strains of V.cholerae O1 isolated in Uganda and the East African region from WGS data
3.Identify any uniqueness in virulence genes or their expression among strains of V.cholerae isolated in Uganda and the East African region from WGS data
4.Identify genes of antimicrobial resistance and infer prevailing mechanisms of antimicrobial resistance among V. cholerae O1 isolated in Uganda

 Uganda 2019-05-14 2022-05-14 Medical and Health Sciences Non-degree Award
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