Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Elizabeth Babirye Katana
ID: UNCST-2022-R009762
Exploring stakeholders’ perceptions of the implementation of a door-to-door vaccination campaign for the novel oral polio vaccine (nOPV2) in Uganda: A qualitative case study
REFNo: HS3445ES

To provide recommendations for future implementation of nOPV2 mass campaigns,To explore the stakeholders’ perceptions towards views, concerns, and recommendations for the key attributes/elements in the door-to-door nOPV2 mass campaigns,To document the experiences of stakeholders during the implementation of the nOPV2 mass campaign conducted in January 2022,
Uganda 2023-11-13 12:49:31 2026-11-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Silver Baryakabona
ID: UNCST-2020-R014307
Evaluation of indigenous soil Bacillus subtilis strains against common cabbage diseases.
REFNo: A174ES

i.To assess the diversity of indigenous soil Bacillus subtilis strains in cabbage fields.
ii.To determine the effect of animal manures on B. subtilis population.
iii.To determine the effect of B. subtilis on incidence and severity of alternaria leaf spot and black rot diseases.
Uganda 2023-11-13 12:48:18 2026-11-13 Agricultural Sciences Non-Clinical Trial Degree Award
GODFREY LUYIMBAZI
ID:
Managing tacit knowledge in higher education institutions: A collaboration engineering approach
REFNo: SIR255ES

To evaluate/validate the designed collaboration engineering process-driven model that supports the retention and management of tacit knowledge in higher education institutions.,To design a collaboration engineering process-driven model that supports the retention and management of tacit knowledge in higher education institutions.,To determine and analyse the requirements for a collaboration engineering process-driven model that supports the retention and management of tacit knowledge in higher education institutions.,To develop a model that can be applied to support the retention and management of tacit knowledge in higher education institutions.,
Uganda 2023-11-13 12:33:38 2026-11-13 Engineering and Technology Non-Clinical Trial Degree Award
Raymond Tweheyo
ID: UNCST-2020-R014507
An investigation into the extent, the associated factors, and the experience of family physician burnout in low- and middle-income countries.
REFNo: HS2262ES

4.1 Aim
To investigate the prevalence of burnout, associated risk factors contributing to its development, associated protective factors and experiences of burnout in family physicians in LMICs.
4.2 Objectives
The aim of this research will be achieved through the following specific objectives:
1. To estimate the prevalence of burnout in family physicians in LMICs
2. To identify associated risk factors or protective factors in family physicians in LMICs
3. To explore the impact and experience of burnout in family physicians in LMICs

UK 2023-11-13 12:31:11 2026-11-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
Improving Practice in Ugandan Medical Retail Sector: a holistic approach to regulation
REFNo: HS3235ES

To work with partners at national, regional and local level to co-design a cluster randomised trial and process evaluation to test the effectiveness of a development governance approach to antibiotic prescribing in the medicine retail sector ,To identify the key elements of a developmental approach to governance and regulation in the Ugandan Medicine Retail Sector,To develop a holistic approach to regulating the Ugandan Medical Retail Sector creating collaborative forms of change among the actors and the communities in which they live as a means of better regulating the sector and improving antibiotic stewardship in Uganda. ,
Uganda 2023-11-13 12:26:41 2026-11-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kennedy Monari Bosire
ID:
REFUGEE EDUCATIONAL OUTCOMES: AN ASSESSMENT OF POLICY MAKER’S PERCEPTIONS ON UGANDA'S PROGRESSIVE EDUCATION APPROACH TO CONFLICT-AFFECTED CHILDREN
REFNo: SS1671ES

The key objectives of the study are to: 1. To identify the driving forces behind the development of Uganda's progressive educational approach and evaluate its impact on improving educational outcomes and meeting the educational needs of refugee children in secondary education. 2. To explore policymakers' perceptions of the inclusivity of Uganda's progressive education approach for refugee children in secondary education and their views on how this approach addresses the social inequality gap for this group of students. 3. To investigate policymakers' perceptions of the appropriateness of the framework for secondary education enrolment of refugee children and the strategies employed to address the challenges related to enrolment, retention, and completion of secondary education for this group of students in Uganda. 4. To examine policymakers' perceptions of the policy challenges hindering the effective achievement of the progressive education approach for conflict-affected children in Uganda and the implications of these challenges on the educational outcomes of this group of students
Kenya 2023-11-13 12:24:28 2026-11-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ali Ssetaala
ID: UNCST-2021-R011817
CHILI- Survey and Discrete choice experiment
REFNo: HS3200ES

General objectives:
1. To estimate cervical cancer screening coverage, screening services knowledge, preferences, and impact of information provision on screening services uptake among women living in Mukono and Wakiso districts, Uganda.
Specific objectives:
1.To determine the cervical cancer screening coverage among women from Mukono and Wakiso districts, Uganda

2.To assess cervical cancer screening knowledge, attitudes and practices (KAP) among women from Mukono and Wakiso districts, Uganda

3.To determine cervical cancer screening preference towards self-sampling compared to provider taken sampling among women from Mukono and Wakiso districts, Uganda.

4.To understand preferences regarding the venue, characteristics of the consultation and attributes of the cervical cancer screening provider.

5.To determine the impact of cervical cancer information provision on cervical cancer screening uptake among women from Mukono and Wakiso districts, Uganda.

Uganda 2023-11-13 12:19:33 2026-11-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
KIZITO MOHAMMED
ID: UNCST-2023-R008004
Mathematical Models for the Dynamics of Tuberculosis and Hepatitis C Co-infection
REFNo: NS674ES

(iv) To investigate the optimal strategy in management of TB-HCV co-infection.,(iii) To determine the role of treatment of HCV on TB progression.,(ii) To investigate the effect of treatment of TB on the HCV progression.,(i) To analyse the transmission dynamics of TB and HCV co-infection using a mathematical model so as to find the conditions for the disease control. ,The main objective of this study is to formulate and analyze mathematical models for the dynamics of TB and HCV co-infection.,
Uganda 2023-11-13 12:18:16 2026-11-13 Natural Sciences Non-Clinical Trial Degree Award
JOSAPHAT KAYOGOZA BYAMUGISHA
ID: UNCST-2019-R001680
A phase II/III, open-label, randomized clinical trial to evaluate the efficacy and safety of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in life-threatening postpartum haemorrhage (PPH) in reducing adverse maternal outcome compared to standard of care in Uganda.
REFNo: HS3240ES

To assess the time to insert the REBOA.,To assess if the proportion of participants with either maternal death and/or emergency hysterectomy is lower in the intervention arm when excluding ‘inevitable’ hysterectomies due to either an irreparable uterine rupture, a pathological placenta growing into the uterus (placenta accreta, increta or percreta) or a pathological uterus, such as a bicorne uterus or one with very large fibroids.,To assess if post-partum haemoglobin concentration is higher in in the intervention arm compared to the comparator arm,To assess if the number of blood transfusion units is lower in the intervention arm compared to the comparator arm.,To assess if the number of participants with acute kidney injury is lower in the intervention arm compared to the comparator arm,To assess if the proportion of participants with maternal deaths is lower in the intervention arm compared to the comparator arm.,To assess if the proportion of participants with emergency hysterectomy, is lower in the intervention arm compared to the comparator arm., To assess the safety of REBOA in a national referral hospital in a low-income country like Uganda.,To assess if the proportion of participants with either maternal death and/or emergency hysterectomy, can be decreased from 50 % in the comparator arm (using standard of care alone) to 30 % or less in the intervention arm (using REBOA). ,
Uganda 2023-11-13 12:15:41 2026-11-13 Medical and Health Sciences Clinical Trial Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
CAtalyzing Strengthened policy aCtion for heAlthy Diets and resiliencE
REFNo: HS3110ES

i.) To analyse annual gender responsive budget expenditures on nutrition and performance outcomes for Financial Years 23/24, 24/25 in Uganda.
ii.) To assess the annual institutional framework for nutrition mainstreaming and performance of its related vote functions at all levels of government in CASCADE implementation districts in Uganda.
iii.) To assess gaps and needs for implementing the current multisectoral coordination framework in CASCADE implementation districts in Uganda.
iv.) To map existing and potential Private Service Providers (PSPs) operating in the field of food and nutrition in CASCADE implementation districts in Uganda.
v.) To assess the existing harmful social and gender norms that affect food, nutrition and agriculture in CASCADE implementation districts in Uganda.
vi.) To analyse barriers and enablers to production, access, preparation and consumption of healthy diets by WRA and Children U5.
vii.) To identify gaps and opportunities for food systems transformation in CASCADE implementation districts in Uganda.
viii.) To assess the state of food and nutrition security in CASCADE implementation districts in Uganda.
Uganda 2023-11-13 12:13:22 2026-11-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
GEORGE MUGAVU
ID:
CRITICAL SUCCESS FACTORS (CSFs) FOR THE ADOPTION OF E-GOVERNMENT IN JINJA LOCAL GOVERNMENT, UGANDA.
REFNo: SS2039ES

To examine the Critical Success Factors for the Adoption of E-government in Jinja Local Government in Eastern Uganda.,
Uganda 2023-11-13 11:59:52 2026-11-13 Social Science and Humanities Non-Clinical Trial Degree Award
Naigwe Kalema Lee
ID:
Global Governance’s Influence on Public-sector Digital Transformation: A case study of the digital “Identity for Development” (ID4D) Initiatives and national digital identity ecosystems in Kenya & Uganda
REFNo: SS1963ES

More research investigating the global “digital transformation for development” (DX4D) policy in a contextual manner is needed. The research seeks an understanding of the progress, challenges, and opportunities surrounding public-sector digital transformation. Hence, in order to examine the evolution, this research attempts to explore and discuss the underlying global governance factors and dynamics that influence the policy formulation and implementation of public-sector digital transformations in the area of digital identity. The project seeks to gain insights and perspectives on the influential linkages between global governance, public administration, and public-sector digital transformation processes. Objectives The overall aim of the research is to understand how global governance and government actors can foster equitable and inclusive approaches to public sector digital transformation. The research objectives are detailed in the following: Draw insights through an analysis of the dynamics that structure such engagements and investigate how powerful countries and global governance actors influence PSDT. Understand how the PSDT and DPI linked to digital identity influence public administration reform processes, particularly the digital and dynamic capabilities of public organisations. Understand how the PSDT and DPI linked to digital identity influence public value and well-being.
USA 2023-11-13 11:56:15 2026-11-13 Social Science and Humanities Non-Clinical Trial Degree Award
Estellina Namutebi Viyaa
ID:
BUILDING COMMUNITY RESILIENCE USING ENVIRONMENTAL JUSTICE IN EXTRACTIVE INDUSTRIES Case Study: The Albertine Graben in Uganda
REFNo: NS488ES

4. To evaluate the activism of stakeholders including the host communities in collaborative governance in the context of extractive industries in the Albertine Graben.,3. To establish the determinants of socio-cultural capital in building community resilience and the governance of ecological commons in the context of extractive industries in the Albertine Graben. ,2. To assess the policy dynamics in addressing the environmentally unjust impacts of extractive industries to rural communities and the ecosystem in the Albertine Graben.,1. To explore the historical accounts of mineral resource mining as determinants of environmental justice and the future of human beings and biodiversity in the Albertine graben.,To examine how rural communities build resilience to extractive industries using the perspective of environmental justice in the Albertine Graben selected districts of Uganda,
Uganda 2023-10-31 20:36:45 2026-10-31 Natural Sciences Non-Clinical Trial Degree Award
Prossy Namyalo Kiddu
ID:
The Path Towards Universal Health Coverage in Uganda: An Evaluation of the Free Healthcare Policy in Public Healthcare Facilities in Uganda
REFNo: HS3050ES

What are the main challenges and opportunities in implementing the free healthcare policy to achieve UHC goals in Uganda,How has the implementation of the free health policy supported the advancement of the right to health in Uganda,How do free healthcare policies advance the goal of financial risk protection in low-income countries,To examine the extent to which the Free Healthcare Policy is contributing to the progress toward UHC in Uganda,
Uganda 2023-10-31 20:33:22 2026-10-31 Medical and Health Sciences Non-Clinical Trial Degree Award
Jean Damascene Niyonsenga
ID:
Ugandan Transitional Care for Traumatic Brain Injury - Outpatient PT
REFNo: HS3079ES

To describe the patient experience of accessing and utilizing outpatient rehabilitation resources.,To describe the current situation of outpatient rehabilitation resource availability after a care transition.,What is the current state of outpatient rehabilitation service availability and utilization for patients who have been discharged from an acute hospitalization due to traumatic brain injury after a road traffic accident? ,
Rwanda 2023-10-31 20:15:30 2026-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda  Tusubira
ID:
Using music to raise awareness of sexual and gender based violence among adolescents at Stand Tall Training Centre RefNo: SPH-2022-327
REFNo: SS2025ES

3. To determine whether music and music videos can be used as a strategy to disseminate information on SGBV ,2. To assess knowledge about sexual and gender-based violence obtained from listening and viewing of professionally recorded music and music video with celebrity endorsed messages ,1. To inform adolescents at Stand Tall Training Centre about sexual and gender-based violence through the use of professionally recorded music and music videos with celebrity endorsed messages,• To raise awareness about sexual and gender-based violence among adolescents at Stand Tall Training Centre through professionally written and recorded music and music videos with celebrity endorsed messages. ,
Uganda 2023-10-31 20:12:05 2026-10-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Samalie Namukose
ID: UNCST-2022-R009222
Implementation of Multiple Micronutrient Supplementation for Pregnant Women in Uganda
REFNo: HS3070ES

3. To inform development of an implementation research study (e.g., define key research questions and inform implementation strategy development) that will inform effective introduction and scaling of MMS in Uganda,2. To assess the MMS demand drivers among pregnant women in Uganda,1. To map the context and extent of readiness for implementing an MMS intervention as part of antenatal care services in Uganda,
Uganda 2023-10-31 20:06:09 2026-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
Multi-level intervention for intersectional stigma reduction to improve HIV outcomes
REFNo: HS2977ES

Adapt the multilevel PRISM ISD-reduction intervention to address ISD for TGW in Uganda.

We will use the ADAPT-ITT model to adapt the multilevel PRISM intervention; specifically, the health facility TFA and individual-level ISD-reduction interventions (multilevel Ssinga nze intervention). Formative research (6 focus group discussions) with healthcare facility (HCF) staff and TGW at four health facilities ranked lowest on the PEPFAR Uganda stigma scorecard will explore ISD drivers and manifestations. We will use ADAPT-ITT to modify the multilevel Ssinga nze intervention comprising the HP+/HIVE3 interventions in consultation with community partners, peers, and providers. We will evaluate the feasibility and acceptability of the adapted Ssinga nze intervention using pre-post surveys, observation of trainings, and pre-post changes in mean scores on stigma scales.

Aim 2: Conduct a pilot hybrid type 1 effectiveness-implementation trial to test the preliminary effectiveness of the adapted multilevel Ssinga nze ISD-reduction intervention on (a) PrEP adherence or (b) viral suppression among TGW using a status-neutral approach.

Two of the health facilities in Aim 1 will be randomly assigned to Ssinga nze (the adapted HP+/HIVE3 intervention) with a 6-month wait-list control. TGW (N=120) will be randomly assigned to receive either Ssinga nze or wait-list control. All will enroll at study clinics, receive HIV testing, and be offered ART or PrEP depending on HIV status. TGW assigned to Ssinga nze will be followed at HIV clinics randomized to HP+; those assigned to wait-list control will attend control health facilities.

Aim 3: Evaluate implementation of Ssinga nze using qualitative methods.
Guided by the Intersectionality-Enhanced Consolidated Framework for Implementation Research [1], we will conduct in-depth interviews with purposively selected cadres of clinic staff trained in HP+ delivery (n=15) and TGW receiving HIVE3 (n=15), and 12 field observations (4 per clinic) to clarify how ISD-reduction intervention delivery may influence HIV prevention and treatment and to understand the actions and synergies of intervention components, assess health facility stigma reduction at HIV clinics for TGW, and interpret implementation data from Aim 2.

Uganda 2023-10-31 20:01:21 2026-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Francis Adyanga Adyanga
ID:
Examining the relocation of the Batwa Indigenous people from the forests and its influence on their Indigenous Education, Customs and Cultures
REFNo: SS2097ES

Determine models for integrating indigenous education system and formal education system that built community/schools capacity to enhance the transmission of Batwa customs and cultures in their current setting,Establish how the integration of the Batwa into the dominant cultures influenced their customs and cultures in their current setting;,Examine the Batwa indigenous pedagogy and its effectiveness in inculcating Batwa custom and culture in their current setting,
Uganda 2023-10-31 20:00:15 2026-10-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stephen Okoboi
ID: UNCST-2019-R001356
Peer Delivered HIV/Syphilis Self-Testing with Assisted Partner Notification Services for Men who Have Sex with Men (MSM) in Uganda
REFNo: HS3021ES

Estimate the cost-effectiveness of peer-delivered HIV/syphilis self-tests and partner services compared to facility-based testing.,Conduct a pilot randomized trial to pilot test the preliminary effectiveness of peer delivered HIV/syphilis self-tests and partner services versus facility-based testing., Conduct formative research to inform implementation of peer delivered self-tests for HIV and syphilis with partner services for Ugandan MSM. ,
Uganda 2023-10-31 19:59:00 2026-10-31 Medical and Health Sciences Clinical Trial Non-degree Award
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