Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Fatumo  Segun Adeyemi
ID:
A single-cell quantitative trait map for peripheral blood in the Ugandan population
REFNo: HS3105ES

The overarching aim of this work is to shed light on the mechanisms that genetic variation affects celltype specific gene expression in peripheral blood mononuclear cells (PBMCs) in the Ugandan population for the first time. The key objectives are: 1. Construct a cell-type specific molecular map of PBMCs in Ugandan population
2. Identification of dynamic allelic effects across PBMCs’ lineages
3. Elucidate causality of cell-type specific genetic variants for cardiometabolic traits and diseases in Uganda
population
 UK 2024-01-24 23:07:48 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 Myocardial Fibrosis and Steatosis Burden and Region-Specific Predictors of Progression among ART-treated Women with HIV infection in sub-Saharan Africa (The MUTIMA study)
REFNo: HS3606ES

2. To quantify myocardial steatosis burden and identify hormonal/metabolic predictors of progression among ART-treated WWH in SSA,1. To characterize myocardial fibrosis burden and identify novel infectious/immunologic predictors of progression among ART-treated women with HIV in SSA. ,
 Uganda 2024-01-24 23:01:55 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Arthur Bagonza
ID:
ASSESSING THE BURDEN AND UNDERSTANDING THE CONTEXT OF LYMPHOEDEMA IN UGANDA: A PREVALENCE STUDY AND SITUATION ANALYSIS
REFNo: HS3713ES

2. To conduct a stakeholder analysis in order to gather essential data for the development of effective lymphoedema treatment and care interventions at both primary and secondary healthcare levels in Buvuma and Napak districts of Uganda. ,1. To determine the prevalence of lymphoedema in Buvuma and Napak districts of Uganda,To determine the burden and context of lymphoedema in Uganda,
 Uganda 2024-01-24 22:55:44 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Household Energy Related Burns Study - Burden and Context Evaluation in Hospital Settings in Uganda (CLEAN-Air (Africa) HERBS)
REFNo: HS3614ES

1. To conduct a retrospective review of hospital records (up to 5 years) to determine the burden of household fuel-related burns and their short-term impacts on affected individuals in Uganda.

2. To conduct a survey to examine the occurrence , severity and determining the circumstances of hospital treated burns caused by household energy use in a study period of 24 months, using the WHO Burn Registry data collection form.

3. To conduct a qualitative study gaming health care workers on knowledge, attitudes and practices of burns care including data collection of burn-related cases

 Uganda 2024-01-24 22:50:16 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Kisaakye
ID:
Feasibility of Routine Screening for Sexual Violence Against Children in Humanitarian Contexts in Uganda
REFNo: SS2265ES

The goal of the study is to expand the access of children/adolescents experiencing sexual violence to comprehensive sexual violence services in refugee settings in Uganda. The study’s specific objective is to assess the feasibility of adapting and implementing a multi-faceted screening intervention to expand such access.
Uganda 2024-01-24 22:46:56 2027-01-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Newton Edward
ID: UNCST-2023-R006537
 Study of Genomic Integrity and Safety of Stem-Cell Gene Therapy in Cohorts in Africa.
REFNo: HS3660ES

The overall aim of this research is to establish safe and accessible gene therapies for sickle cell disease by comparing and contrasting cohorts in Africa to the data already obtained from the USA and UK thus establishing a more accurate authentic dataset. We hypothesise that patients with SCD may have elevated somatic mutation rates as compared to healthy non-SCD individuals and that the mutational processes driving the acquisition of these genetic lesions are varied from individual to individual.
 UK 2024-01-24 22:45:26 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Harriet Ajilong
ID: UNCST-2022-R005889
 Assessing Vitamin D serum levels in HIV-positive adolescents 10-19 years with depression in Northern Uganda
REFNo: HS3454ES

To determine the burden of depression in HIV-positive adolescents at Gulu RRH,To assess for serum Vitamin D levels in HIV Positive adolescents 10-19 years with depressive symptoms in Gulu Regional Referral Hospital Methods,
 Uganda 2024-01-24 22:30:43 2027-01-24 Medical and Health Sciences Clinical Trial Non-degree Award
Mercy Kainobwisho Kyomugasho
ID:
AN ANALYSIS OF THE BARRIERS TO PROTECTION AND COMMERCIALIZATION OF TRADEMARK ASSETS BY SMES IN THE NON-ALCOHOLIC BEVERAGE MANUFACTURING S IN UGANDA.
REFNo: SS2153ES

specific objectives of the study are to;
i. To investigate the relationship between trademark protection, licensing, valuation, collaterisation and commercialisation by SMEs in the non- alcoholic beverages in the manufacturing sector.
ii. To identify the barriers to protection, licensing, valuation and collateralisation of trademarks by SMEs in the manufacturing sector.
iii. To examine the legal and institutional framework for protecting, licensing, valuation and collateralisation of trademarks in Uganda.
iv. To propose effective ways for enhancing the protection, licensing, valuation and collateralisation of trademarks by SMEs in the manufacturing sector in Uganda

 Uganda 2024-01-23 18:58:37 2027-01-23 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph Rujumba Rujumba
ID: UNCST-2022-R011160
 Combining monthly dihydroartemisinin-piperaquine and azithromycin for the post-discharge management of children with severe anaemia in Malawi, Kenya, and Uganda: Post-Discharge Malaria Chemoprevention -PDMC-II (acceptability and feasibility sub-study)
REFNo: HS3669ES

2)Explore perspectives of health care providers and caregivers on the feasibility of implementing PDMC with DP + AZ in children diagnosed with severe anaemia in Malawi and Uganda and generate insights for successful integration and scalability of PDMC with DP+AZ in resource-limited settings.,1)To assess health care provider and caregiver acceptability of PDMC with DP + AZ in children with severe anaemia at Malawi, Kenya, and Uganda trial sites. ,To determine the acceptability and feasibility from the health provider and patient/guardian perspective of delivering or receiving dihydroartemisinin-piperaquine (DP) and azithromycin (AZ) for the post-discharge management of children with severe anaemia in Malawi, Kenya, and Uganda.,
 Uganda 2024-01-23 18:57:41 2027-01-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jane Nabwowe -
ID:
ALLELE FREQUENCY DATABASE FOR 21 SHORT TANDEM REPEATS IN THE UGANDAN POPULATION
REFNo: NS716ES

To establish the Ugandan population Y-Chromosome haplotype frequency database,To develop Ugandan population specific 21 autosomal STR markers and Y- chromosome haplotype markers allele frequency data ,To determine population genetic homogeneity among the selected tribes in Uganda ,To determine the genetic diversity of the 21 STRs in a Ugandan population by calculating the forensic and paternity efficiency parameters ,
 Uganda 2024-01-23 18:56:08 2027-01-23 Natural Sciences Non-Clinical Trial Non-degree Award
MARY AJIKO MARGARET
ID:
Prevalence of Paediatric burn injuries Admitted to a hospital in Teso sub-region Eastern Uganda: lessons for prevention
REFNo: HS3484ES

The main objective of this study is to investigate the causes, characteristics, patterns, geographic determinants of paediatric burns and identifying the barriers and enablers to their prevention in a home. Specific Objective of the Study 1. To examine the typical patterns and causes of paediatric burn injuries leading to hospitalization. 2. To establish care givers’ understandings of the injury to their children, considering both injury determinants and preventive means. 3. To assess the effects of various characteristics of the living area on paediatric burn injuries. 4. To determine the enablers and barriers to the creation of safe environment, the implementation of safe practices and the use of products that control or prevent childhood burn injuries in the home.
Uganda 2024-01-23 16:58:07 2027-01-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Margaret Mangheni Najjingo
ID:
Women empowerment, normative influence and project outcomes in Central Uganda
REFNo: SS1942ES

To identify factors that influence women’s economic empowerment within farming communities.

To explore the community construction of femininities and how it influences women’s economic empowerment within agricultural project intervention areas.

To explore the community construction of masculinities and how it influence women’s economic empowerment within agricultural project intervention areas

To find out the factors that influence women’s economic empowerment and household food security within agricultural project intervention areas

 Uganda 2024-01-22 11:38:01 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 EFFECTIVENESS OF THE PARTNER-LED IMPLEMENTATION IN IMPROVING DIGITAL PAYMENT AND CAMPAIGN QUALITY DURING THE YELLOW FEVER CAMPAIGN IN UGANDA: AN EXPLORATORY STUDY
REFNo: SS2221ES

To determine gender norms and relations and their influence on health workers’ response to payment systems (cash vs mobile money) and how these affect the health workers’ performance and motivation in yellow fever vaccination campaigns,To explore the effect of implementing a partner-led digital payment system on the Motivation, Satisfaction, and performance of vaccination campaign health workers,To establish the vaccination coverage of yellow fever in different geographies (equity),To document partner-led implementation process of the Yellow Fever Mass Vaccination campaign,To assess the effectiveness of partner-led Yellow Fever campaign and its effect on digital health worker payments and campaign coverage in Uganda.,
 Uganda 2024-01-22 11:26:43 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 OUTCOMES OF PEDIATRIC PATIENTS DIAGNOSED BY MORPHOLOGY ALONE VERSUS FLOW CYTOMETRY PLUS MORPHOLOGY: A RETROSPECTIVE STUDY
REFNo: HS3352ES

To compare the treatment outcomes between patients diagnosed with the help of flow cytometry with those diagnosed without the help of flow cytometry.,To determine the accuracy of diagnosis of acute leukemia between patients diagnosed with the help of flow cytometry with those diagnosed without the help of flow cytometry.,To assess the time to treatment initiation among patients diagnosed with the help of flow cytometry and those diagnosed without the help of flow cytometry,
 Uganda 2024-01-22 11:25:41 2027-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Using Video-Enhanced Teaching to Increase Maternal Participation in Neonatal Hospital Care
REFNo: SS2030ES

3. To evaluate by survey the perspectives of healthcare workers on their availability to devote to video-assisted maternal education in a neonatal hospital unit in Uganda.,2. To identify maternal and/or neonatal factors that impact the amount of time needed to train mothers to weigh their baby, assess for danger signs, and track feeds using video-assisted teaching.,1. To determine the mean nursing time required to train mothers to perform three specific tasks: (1) weigh their baby, (2) assess for danger signs, and (3) track feeds when facilitated by video-assisted teaching.,The purpose of this study is to evaluate a video that teaches mothers how to monitor their baby in a neonatal hospital unit in Uganda. This is with the goal of reducing the amount of time healthcare workers need to spend teaching mothers and ultimately improving the quality of care that sick and small newborns receive in the hospital. ,
 Uganda 2024-01-22 10:45:51 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Grace Kebirungi
ID:
A QUALITATIVE STUDY ON THE CAUSES OF SLOW ADOPTION OF VIRTUAL REALITY IN MEDICAL EDUCATION IN KAMPALA, UGANDA
REFNo: SIR261ES

Primary objective: To assess the causes of slow adoption of VR in medical education in Kampala ,Uganda Secondary objectives: 1. To identify perceptions of medical students, interns, lecturers at Makerere School of Medicine, doctors and medical association leads in Kampala towards use of VR in medical education. 2.To assess the VR programming capacity in Kampala, Uganda 3 To identify key policy guidelines that would empower VR in Uganda.
Uganda 2024-01-11 13:14:59 2027-01-11 Engineering and Technology Non-Clinical Trial Non-degree Award
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
 Regulating alcohol packaging and supply to protect health in Sub-Saharan Africa: evidence from policy systems in Malawi and Uganda (RAPSSA study)
REFNo: HS3130ES

General objective
1. To identify how regulatory controls on alcohol production and distribution can be improved and effectively implemented in Sub-Saharan Africa to reduce the availability of cheap, single-use products and related harms
2. To explore contextual factors important for the transferability of findings to other Sub-Saharan countries, to inform alcohol policy development and implementation across the region.


Specific objectives

1. To identify the adoption and formulation of the bans, what mechanisms for implementation were proposed and put in place, how the bans were enforced in practice, as well as stakeholder and public perceptions of, and explanations for, intended and unintended consequences of the bans.
2. To explore contextual factors important for the transferability of findings to other Sub-Saharan countries, to inform alcohol policy development and implementation across the region.

 Uganda 2024-01-11 12:40:52 2027-01-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel Kibuuka Musoke
ID: UNCST-2021-R011749
 Evaluation of the impact of the Public Justice System strengthening program on violence against women and children in Uganda
REFNo: SS1980ES

d) To measure change in the status of empowerment and protection of women and children against sexual and intimate partner violence including establishing the prevalence of violence against women and children. ,c) To assess change in the performance of the justice system in prevention and response to violence against women and children in Uganda, with a focus on the ability of the criminal justice processes to secure justice for victims of intimate partner violence and sexual violence against children, b) To explore changes in stakeholder confidence in the criminal justice system and the reliance of victims / survivors of intimate partner violence and child sexual violence on the criminal justice system for redress. ,a) To assess the coherence and relevance of IJM’s VAWC program including profiling changes in the legal landscape, framework and processes for handling cases of violence against women and children in Uganda,The general aim of the study is to evaluate how strengthening the public justice system to enforce law (supply side) and empowerment of sexual and intimate partner violence survivors to undertake justice (demand side) contribute towards the protection of children and women from sexual and intimate partner violence. The evaluation will be guided by the Organization for Economic Co-operation and Development (OECD) Development Assistance Committee (DAC) evaluation criteria of Relevance, Coherence, Effectiveness, Efficiency, Impact, and Sustainability to measure impact,
 Uganda 2024-01-11 12:39:14 2027-01-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
DENIS OKELLO
ID: UNCST-2023-R007227
 Profiling Medicinal Plants and the Corresponding Community Conservation Practices within Kigezi Region
REFNo: NS667ES

Assess the community conservation strategies for priority medicinal plants in Kanungu, Kisoro and Rubanda districts.,To assess the cultural practices in Kanungu, Kisoro and Rubanda districts to ensure sustainable utilization and knowledge transfer of the medicinal values of these plants.,To assess traditional knowledge practices regarding medicinal plants used by communities in Kanungu, Kisoro and Rubanda districts.,To identify and document medicinal plants used by communities in Kanungu, Kisoro and Rubanda districts.,To profile medicinal plants in Kanungu, Kisoro and Rubanda districts in Kigezi region and assess local community conservation practices,
 Uganda 2024-01-11 12:35:14 2027-01-11 Natural Sciences Non-Clinical Trial Non-degree Award
Richard Mayanja
ID: UNCST-2022-R009948
 Genetic Determinants of Kidney Function in Sub-Saharan Africa
REFNo: HS3372ES

The overall aim of this project is to identify the genetic determinants of chronic kidney disease in sub-Saharan Africa
 Uganda 2024-01-11 12:32:07 2027-01-11 Medical and Health Sciences Non-Clinical Trial Degree Award
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