Johnblack Kabukye Kabaalu
ID: UNCST-2019-R001109
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Requirements for an Interactive Voice Response system for provision of cancer information to patients and general public in Uganda
REFNo: HS418ES
To co-create a program theory for development, implementation and evaluation of IVR system for provision of cancer information to patients and general public in Uganda
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Uganda |
2019-07-10 |
2022-07-10 |
Medical and Health Sciences |
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Degree Award |
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Stephen Asiimwe
ID: UNCST-2019-R000059
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Quality of Life and Aging with HIV in Rural Uganda
REFNo: HS419ES
Aim 1: Use qualitative methods to develop a conceptual framework explaining how HIV influences quality of life among older-aged people in Uganda.
We will conduct semi-structured interviews among 60 study participants stratified by sex and HIV serostatus to explore conceptualizations of and domains that meaningfully impact quality of life. We will use an inductive analytic approach to identify locally relevant domains that determine health and quality of life for older people in our study population. The over-arching goal of Aim 1 is to develop a conceptual framework and optimize selection of measures related to quality of life to be used in study Aims 2 and 3.
Aim 2: Compare trajectories of social, cognitive, and physical functioning, and global quality of life by HIV serostatus in Uganda.
We will use the Aim 1 findings to inform appropriate selection of measures. We will observe 600 participants annually for four years to collect outcome measures of physical, cognitive, and social functioning, and quality of life. We hypothesize that PLWH will exhibit steeper declines in physical, cognitive, and social functioning, and quality of life compared to HIV-negative individuals.
Aim 3: Identify intervention targets, and assess the acceptability and feasibility of promising interventions, to improve functioning and quality of life among older PLWH in Uganda.
We will fit mixed effects regression models with data from the Aim 2 cohort to identify determinants of quality of life among PLWH, including social (e.g. stigma, depression, familial deaths), biomedical (e.g. comorbidities, opportunistic infections), and HIV-specific factors (e.g. viral load, nadir CD4, sCD14). We hypothesize that HIV-associated stigma and familial deaths due to HIV will predict faster decline in functional domains and quality of life among older PLWH. We will supplement these analyses with participant and stakeholder workshops to assess the preliminary acceptability and feasibility of potential interventions to improve quality of life in this population.
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Uganda |
2019-07-10 |
2022-07-10 |
Medical and Health Sciences |
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Non-degree Award |
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Samuel Kyobe
ID: UNCST-2019-R000108
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Role of Class I HLA Alleles in HIV Disease Progression in Botswana and Uganda
REFNo: HS421ES
1) To describe the baseline characteristics of the pediatric HIV cohort in Uganda and Botswana.
2) To describe the distribution of class I HLA alleles in pediatric HIV in Botswana and Uganda.
3) To determine the HLA Class I alleles that are associated with HIV disease progression in Botswana and Ugandan African paediatric populations.
4) To determine the structural and functional (binding) characteristics of those class I HLA alleles associated with HIV disease progression.
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Uganda |
2019-07-10 |
2022-07-10 |
Medical and Health Sciences |
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Degree Award |
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Roy Carr-Hill Ngugi
ID:
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Impact Evaluation of interventions to prevent Violence Against Children in Schools (VACiS) in Uganda
REFNo: SS322ES
1. Assess the extent to which the objectives of the teacher training and life skills education through school clubs are consistent with beneficiaries’ needs as far as creating a safe learning environment
2. Determine the impact (positive, negative, intended and unintended) of teacher training and learners’ life skills education through school clubs on reducing violence against children in schools.
3. Assess the likelihood of continuation of benefits from the VACiS interventions after UNICEF assistance to supported schools has ceased
4. Provide recommendations on how to strengthen teacher
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UK |
2019-07-04 |
2022-07-04 |
Social Science and Humanities |
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Non-degree Award |
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Hailey Tiarks Jo
ID:
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Testing the role of turbidity on the visual sensitivity of an African cichlid fish (Pseudocrenilabrus multicolor victoriae)
REFNo: NS90ES
The goal of the proposed research is to better understand the influence of turbidity and other environmental stressors on behavior and development of visual and behavioural traits in an African cichlid fish (Pseudocrenilabrus multicolor victoriae). Environmental degradation can introduce persistent environmental stressors that impair many behaviors in fishes that could influence their ability see their environment, which can obscure reproduction, predation, and other inter/intra species visual cues. It is important to understand how species continue to persist in degraded tropical aquatic habitats to help conserve essential biodiversity for the health of aquatic ecosystems. We will investigate how important stressors, such as turbidity, influence the behavior and development of visual traits in a widespread African cichlid in the lakes, rivers, and swamps near Lake Nabugabo, western Uganda.
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USA |
2019-07-01 |
2022-07-01 |
Natural Sciences |
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Degree Award |
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