Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Janet Nakigudde
ID: UNCST-2019-R000444
TESTING MULTI-LEVEL SCALE-UP STRATEGIES TO IMPLEMENT A SCHOOL-BASED POPULATION APPROACH OF MENTAL HEALTH PREVENTIVE INTERVENTION: UGANDA
REFNo: HS5647ES

General Objective
The overall goal of this study is to address vertical and horizontal scale-up implementation framework gaps in Uganda. This study will test new recommended vertical scale-up and sustainability implementation strategies and study impact and underlying mechanisms when the new scale-up model is applied.
This research will guide the development of evidence-informed theoretical frameworks and processes to effectively institutionalize EBIs in LMICs such as Uganda. To achieve this goal, we will carry out 4 sequential steps (4 aims).
Specific Objectives
1.
To establish a cross-level partnership and strengthen stakeholders/leaders’ advocacy capacity to make evidence-based informed children’s mental health policy and practice decisions and to facilitate the EBI institutionalization through the educations system illustrated in figure 1.
2.
To develop implementation Protocols in collaboration with cross level partners (established in Aim 1) based on a new multilevel train-the-trainer scale-up framework to support the EBI/PD scale-up.
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3.
Implement the new Protocols for scale-up and test the relative value of additional implementation supports intended to sustain teacher EBI practices through a Hybrid III cRCT.
4.
To explore underlying scale-up and sustainability implementation mechanisms.
Uganda 2025-04-11 16:03:54 2028-04-11 Medical and Health Sciences Clinical Trial Non-degree Award
Jacklyn Arinaitwe Makaaru
ID: UNCST-2024-R015354
Impact Evaluation of Childcare Services for Kampala Market Women Study
REFNo: SS3696ES

Primary objectives:
a. To assess the labour market effects (labour force participation and productivity) of gaining access to childcare services by women working in markets in Kampala.
b. To assess the effects of gaining access to childcare services on the well-being of women working in markets in Kampala.
c. To assess the effects of gaining access to childcare services on the well-being of children of women working in markets in Kampala.

Secondary objective:
d. To assess important dimensions of heterogeneity, related to accessibility, wealth levels, women’s agency, and child’s age.
e. To explore secondary outcomes of access to childcare services by women working in markets in Kampala including spillover effects on other household members, and changes in mobility.


Uganda 2025-04-11 16:00:39 2028-04-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Deborah Nakalyowa Luggya
ID: UNCST-2024-R003382
Menstrual Hygiene Management and materials: Experiences of Adolescent Girls with Disability in Kamuli District, Uganda
REFNo: SS3523ES

a) To examine the current state of menstrual hygiene management among adolescent girls with disabilities in Kamuli district.
b) To identify the unique needs and challenges of adolescent girls with different disabilities in managing menstruation in Kamuli district.
c) To assess the factors influencing availability, accessibility, and affordability of reusable sanitary wear for adolescent girls with disabilities in Kamuli district.
d) To explore the socio-cultural factors influencing menstrual hygiene practices among adolescents with disabilities in Kamuli district.
e) To assess the effects of inadequate menstrual hygiene management on the overall health, well-being, and participation of adolescent girls with disabilities in Kamuli district.

Uganda 2025-04-11 15:55:45 2028-04-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
ATURINDA JOSHUA
ID: UNCST-2024-R002017
NARRATIVES OF RESILIENCE: KIGA FOLKTALES IN CULTIVATING SUSTAINABLE CULTURAL IDENTITY
REFNo: SS3803ES

i. To establish the historical moral and educational value embedded within Kiga traditional folktales.
ii. To analyze the importance of Kiga folktales in cultivating sustainable Cultural Identity
iii. To design innovative interventions that ensure sustainability of traditional Kiga folktales.

Uganda 2025-04-11 15:53:53 2028-04-11 Social Science and Humanities Non-Clinical Trial Degree Award
Denis Okethwangu
ID: UNCST-2024-R004883
Health system resilience in the context of infectious disease outbreaks: Exploring concepts and experiences, frameworks and tools in Uganda
REFNo: HS5718ES

1. Explore the understanding of the concept of health systems resilience, and determinants that influence building a health system resilient to infectious disease epidemics in Africa.
2. Critically assess the JEE and GHSI tools for their appropriateness to measure resilience to infectious disease outbreaks in Uganda and based on the results adapt/develop a context-specific tool for measuring HSR to infectious disease outbreaks.
3. Assess the resilience of the health systems of Mubende and Kassanda Districts during response to the Ebola virus disease outbreak in 2022 using the context-specific tool and design interventions or strategies to address identified gaps towards building a resilient health systems to infectious disease outbreaks.
4. Identify enablers and barriers to the implementation of proposed strategies and interventions aimed at building a resilient health system to infectious disease epidemics.
Uganda 2025-04-11 15:28:50 2028-04-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Moses Awal
ID: UNCST-2024-R016231
DEVELOPMENT OF POWER FLOW ANALYSIS TECHNIQUE OF 132-KV POWER TRANSMISSION GRID: A CASE STUDY OF UGANDA\'S ELECTRIC POWER SECTOR
REFNo: SIR483ES

PID parameter optimization using water cycle algorithm (WCA).,The current state of AGC in interconnected power systems.,
Uganda 2025-04-11 15:27:19 2028-04-11 Engineering and Technology Non-Clinical Trial Degree Award
Julius Okuni Boniface
ID: UNCST-2019-R000963
PERFORMANCE OF SELECTED NOVEL MOLECULAR POINT OF CARE DIAGNOSTICS FOR EMERGING AND ONGOING EPIDEMICS AND ANTIMICROBIAL RESISTANCE IN UGANDA (PREPARE-TID)
REFNo: A584ES

General Objective To validate novel rapid molecular assays in nucleic acid extraction, point of care testing and One health surveillance of AMR, CCHF, RVF and other arthropod borne pathogens responsible for emerging and ongoing epidemics in Uganda Specific Objectives (i) To determine the prevalence of Congo Crimean Haemorrhagic fever (CCHF) in different tick species collected at Kampala City Abattoir. (ii) To determine the diagnostic performance of a novel NA extraction on selected Assays for rapid detection of CCHF, RVF and AMR. (iii) To determine the diagnostic performance the multiplex qPCR-based Point of Care diagnostic assay for detection of CCHF, RVF and AMR. iv) To appraise the existing one health point of care diagnostics for detection of zoonotic pathogens using a meta-analysis. (v) To determine the reliability of novel next generation sequencing platform for detection of AMR markers for Staphylococcus aureus, E. coli, Klebsiella, Pseudomonas aeruginosa from waste water samples.
(vi) To document the conditions required for the optimal performance of the test protocols.
(vii) To evaluate the field performance of the Multiplex qPCR one Health point of care diagnostic and the reliability of novel Next Generation platform in an emergency outbreak situation.

Uganda 2025-04-11 15:16:42 2028-04-11 Agricultural Sciences Non-Clinical Trial Non-degree Award
Fred Kaggwa
ID: UNCST-2022-R008842
Dialogues of Delivery: Fine-Tuning Large Language Models for Prenatal and Perinatal Care in East African Languages
REFNo: HS5739ES

General Objective
To develop, evaluate, and deploy an open-source fine-tuned Large Language Model capable of answering prenatal and perinatal care questions in Luganda, Runyankore-Rukiga, and Swahili, thereby enhancing access to relevant health information among expectant mothers.
Specific Objectives
1. Collect, curate, and build high-quality clinical text corpora and datasets specific to these languages and healthcare needs.
2. Develop a pipeline for fine-tuning domain-specific LLMs to support prenatal and perinatal care in Luganda, Runyankore-Rukiga, and Swahili.
3. Deploy and evaluate the effectiveness of the fine-tuned domain-specific LLMs in community health settings, ensuring linguistic, cultural, and contextual relevance.

Uganda 2025-04-11 15:13:35 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Omulepu Isaac
ID: UNCST-2022-R003531
PREVALENCE AND FACILITATORS OF RESPECTFUL MATERNITY CARE DURING CHILDBIRTH AMONG WOMEN IN IN KAYUNGA REGIONAL REFERRAL HOSPITAL AND IMPACT OF DISRESPECTFUL AND ABUSIVE CARE ON MATERNAL HEALTH SEEKING BEHAVIOR
REFNo: HS5710ES

1. To determine the prevalence of RMC during childbirth among women in Kayunga RRH .
2. To assess for the facilitators of RMC during childbirth among women in Kayunga RRH
3. To explore the impact of disrespectful and abusive care of women during childbirth to maternal health seeking behavior.

Uganda 2025-04-11 14:48:37 2028-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nicolas Laing
ID: UNCST-2024-R015317
The impact of patient preferences, knowledge and attitudes on the demand for and supply of formal health care in Uganda
REFNo: SS3699ES

Objecitve,
New Zealand 2025-04-11 14:45:57 2028-04-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
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