Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Francis Ssali
ID: UNCST-2021-R012134
A5424 Menopausal Hormone Therapy for Women Living with HIV (HoT)
REFNo: HS7391ES


1.2 Primary Objective

1.2.1 Determine the effects of HT on VMS in WLWH in the late menopausal transition or early postmenopause.

1.3 Secondary Objectives

1.3.1 Evaluate the safety and tolerability of HT as compared to placebo.

1.3.2 Determine the effect of HT on neurocognition.

1.3.3 Determine the effect of HT on mood.

1.3.4 Determine the effect of HT on sleep.

1.3.5 Determine the effect of HT on quality of life.

1.3.6 Determine the effect of HT on sexual function.

1.3.7 Determine the effect of HT on weight, waist circumference, and waist-to-hip ratio.

1.4 Exploratory Objectives

1.4.1 Determine the effect of HT on markers of bone turnover.

1.4.2 Determine the effect of HT on markers of cardiometabolic health.

1.4.3 Determine the effect of HT on systemic markers of inflammation and immune activation.

1.4.4 Determine the effect of HT on HIV reservoir size, clonality, and activity.

1.4.5 Determine the effect of HT on measures of physical function.

1.4.6 Determine the effect of HT on the rectal and vaginal microbiome.

1.4.7 Explore the effect of HT on all primary and secondary outcomes by antiretroviral regimen.

1.4.8 Explore exposure-response relationships between estradiol pharmacokinetics (PK) and study outcomes in those treated with estradiol.

1.4.9 Evaluate acceptability and feasibility of ambulatory monitors for VMS and sleep on a subset of participants.

1.4.10 Explore agreement between subjective VMS frequency with objective VMS frequency in a subset of participants.


Uganda 2026-04-24 13:20:15 2029-04-24 Medical and Health Sciences Clinical Trial Non-degree Award
Peter Olupot Simon
ID: UNCST-2025-R022744
Implementation of Sustainable Public Procurement in the Procurement of Works in Uganda’s Central Government Entities
REFNo: SS5085ES

i. To examine the relationship between external pressures and implementation of SPP.
ii. To examine the relationship between resource heterogeneity and implementation of SPP.
iii. To examine the relationship between stakeholder engagement and implementation of SPP.
iv. To examine the mediating role of resource heterogeneity in the relationship between external pressures and implementation of SPP.
v. To examine the mediating role of resource heterogeneity in the relationship between stakeholder engagement and implementation of SPP.
vi. To examine the moderating effect of procurement officers’ attitude in the relationship between resource heterogeneity and implementation of SPP.
vii. To examine how procurement officers’ attitude will moderate the relationship between external pressures and implementation of SPP through resource heterogeneity.
viii. To examine how procurement officers’ attitude moderates the relationship between stakeholder engagement and implementation of SPP through resource heterogeneity.

Uganda 2026-04-20 9:42:42 2029-04-20 Social Science and Humanities Non-Clinical Trial Degree Award
Robert Mboizi Baldwin
ID: UNCST-2020-R014356
Optimising Eligibility Criteria for Participant Selection in Maternal Vaccine Trials in Low-Resource Settings (ACCESS).
REFNo: HS7404ES

1. To conduct a systematic review and analyse existing eligibility criteria used in maternal vaccine trials globally, with a focus on their applicability and limitations in low-resource settings.

2. Determine the proportion of women ineligible to participate in maternal vaccine clinical trials at Kawempe National Referral Hospital using an eligibility assessment tool.

3. Determine the pregnancy outcomes in women ineligible for maternal vaccine trials at Kawempe National Referral Hospital using an eligibility assessment tool.

4. Identify factors associated with pregnancy outcomes among pregnant women excluded from trial participation.

Uganda 2026-04-20 16:50:32 2029-04-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Yudaya Nakyeyune
ID: UNCST-2026-R024597
Using Play in Culturally Responsive Ways to Enhance Children’s Numeracy Skills Achievement in Refugee-Hosting ECD Centers in Kampala
REFNo: SS5116ES

1. To analyze children's voices of learning through play in refugee hosting ECD centers in Kampala.
2. To identify the challenges teachers encounter when using play in the teaching of numeracy in refugee hosting ECD centers in Kampala
3 To establish the impact of engagement in Continuing Professional Development (CPD) on teachers' knowledge regarding the use of play-based methods in culturally responsive ways in refugee hosting ECD centers in Kampala
4. To assess the impact of engagement in culturally responsive learning through play activities on children's numeracy achievement in refugee hosting ECD venters in Kampala
Uganda 2026-04-20 16:47:28 2029-04-20 Social Science and Humanities Clinical Trial Degree Award
PIUS OKELLO ROBERT
ID: UNCST-2026-R024675
School Management Functions and Academic Performance of Students in Government-Aided Secondary Schools A Case of Dokolo District, Uganda
REFNo: SS5162ES

Purpose of Study
To investigate the contribution of School Management Functions and its relationship with academic Performance of Students in Government-aided Secondary Schools in Dokolo District.


Specific Objectives
1. To evaluate the effect of management planning function on academic performance of students in Government-aided Secondary Schools in Dokolo District.

2. To analyze the effect of management organizing function on academic
performance students in Government-aided Secondary Schools in Dokolo District.

3. To assess the role of management controlling function on academic performance of students in Government-aided Secondary Schools in Dokolo District.

4. To investigate the mediating effects of perceived on relationship between school management functions and academic performance of students in government-aided Secondary Schools in Dokolo District.
Uganda 2026-04-20 16:25:31 2029-04-20 Social Science and Humanities Non-Clinical Trial Degree Award
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