Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Jafesi Pulle
ID: UNCST-2020-R014213
Developing and Testing a Package of Interventions to Improve Patient Engagement in Rheumatic Heart Disease Care in Northern Uganda: A mixed Methods Study
REFNo: HS5605ES

Objective 1: To describe the treatment cascade of RHD care in Kitgum district and determine the associated factors.
Objective 2: To explore the barriers and facilitators of patient engagement in RHD care in Kitgum district.
Objective 3: To co-develop a package of interventions to improve patient engagement in RHD care.
Objective 4: To evaluate the effectiveness of a package of interventions to improve patient engagement in RHD care in Kitgum district.
Uganda 2025-02-20 17:21:09 2028-02-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
WOMEN’S INCLUSIVE SERVICES FOR HEALTH ACCESS TO QUALITY HEALTHCARE FOR PREGNANT AND BREASTFEEDING WOMEN WITH DISABILITIES IN UGANDA
REFNo: HS5552ES

1. To identify and understand the existing disparities in HIV and maternal healthcare services affecting pregnant and breastfeeding mothers with disabilities
2. To elicit the perceptions and experiences of people with disabilities that affect their health-seeking behavior, especially for HIV, maternal, and reproductive health services.
3. To promote awareness and education among women about their healthcare rights and available services.
4. To collaborate with relevant stakeholders, including healthcare providers, policymakers, and community organizations, to implement sustainable changes.


UK 2025-02-20 17:18:32 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PRECIOUS NATUHWERA
ID: UNCST-2024-R003154
Clinical presentations, prevalence and factors associated with cranial hemorrhages among neonates admitted at Mbarara Regional Referral Hospital
REFNo: HS5377ES

General objective
To determine the clinical presentations, prevalence and factors associated with cranial haemorrhages among neonates admitted at Mbarara Regional Referral Hospital.
Specific objectives
1.To determine the prevalence of extracranial and intracranial haemorrhages among neonates admitted to the NICU of Mbarara RRH.
2.To describe the clinical profiles of neonates with cranial haemorrhages admitted to the NICU at Mbarara RRH
3.To determine the factors associated with cranial haemorrhages among neonates admitted to the NICU at Mbarara RRH.

Uganda 2025-02-20 17:16:30 2028-02-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Ashirafu  kule masudi
ID: UNCST-2024-R004729
TEACHER’S COMMITMENT AND STUDENTS’ ACADEMIC PERFORMANCE IN PUBLIC SECONDARY SCHOOLS IN KASESE DISTRICT, UGANDA
REFNo: SS3529ES

i. Examine the relationship between teachers’ job satisfaction and students’ academic performance in public secondary schools in Kasese District, Uganda.
ii. To determine the relationship between work environment and students’ academic performance in public secondary schools in Kasese District, Uganda.
iii. Establish the relationship between teacher’s level of professional training and development on students’ academic performance in public secondary schools in Kasese District, Uganda
iv. Evaluate the relationship between school leadership and students’ academic performance in public secondary schools in Kasese District, Uganda.

Uganda 2025-02-20 17:15:03 2028-02-20 Social Science and Humanities Non-Clinical Trial Degree Award
Naomi Nsubuga
ID: UNCST-2024-R003628
School Eye Health Rapid Assessment (SEHRA) to review the policy environment and determine the magnitude and patterns of eye health conditions among public primary school children in select regions in Uganda.
REFNo: HS4803ES

2. To determine the magnitude, characteristics and any patterns of eye health conditions among children in selected public primary schools across the six selected regions in Uganda.,1. To conduct a rapid review of the policy, strategy, institutional and service delivery environment for a school eye health programme in Uganda. ,To review the policy environment on school eye health and determine the magnitude and patterns of eye health conditions among public primary school children in selected regions in Uganda,
Uganda 2025-02-20 17:12:48 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
James Byarugaba
ID: UNCST-2024-R004225
Midterm evaluation of Our Rights, Our Future PLUS (O3PLUS)
REFNo: SS2565ES

The evaluation objectives are to:
1. Ascertain the relevance, coherence, effectiveness, efficiency, and sustainability of the O3PLUS Project.
2. Assess progress against targets set at baseline, validate, and populate the results framework.
3. Identify opportunities, challenges, innovative practices, and lessons that will be useful for strengthening and enhancing the implementation of the remaining project period.
4. Provide conclusions and actionable recommendations to shape future programming and implementation of similar initiatives.

Uganda 2025-02-20 17:11:11 2028-02-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Christine  Muhumuza
ID: UNCST-2023-R008646
Improving Family Wellness for Couples in Central Uganda 2024-2029
REFNo: HS5523ES

The study aims are to:

(1) In a cluster randomised trial, compare the efficacy of the FH=FW intervention vs. a time/attention matched comparator intervention at increasing modern contraceptive use and reducing unintended pregnancy among couples with an unmet need for family planning through 24-months, and identify potential mediators of the intervention effect.

(2) Determine the intervention’s effect on, and determinants of, contraceptive continuation.

(3) Through a mixed-methods process evaluation, explore factors affecting the implementation of the intervention in order to improve feasibility, acceptability, and the likelihood of future adoption and sustainment
Uganda 2025-02-20 17:09:28 2028-02-20 Medical and Health Sciences Clinical Trial Non-degree Award
Sally Andersson Lova Sofia
ID: UNCST-2024-R002577
Agrarian Governmentality & Interacting Policies: Young Farmers' Subjectivity and Agency in the Gulu District, Uganda
REFNo: SS3634ES

To gain knowledge on how young farmers in Uganda socially navigate the subjectivities constructed in the policies, using their agency to internalise, adopt, or adapt them, or to create counter-conduct subjectivities. ,To understand how young farmers experience challenges and opportunities in farming, and how they view the solutions to these challenges offered in various interacting agrarian policies. ,To explore the various subjectivities for young farmers found within problem representations in the governmental policies, illuminating possible synergies and discords between policies attempting to solve different challenges, as subjectivities offer different possible courses of actions to young farmers.,To explore how young farmers in Uganda interact with synergies and discords in governmental policy responses to climate change and the associated challenges and opportunities facing young farmers. ,
Sweden 2025-02-14 17:37:37 2028-02-14 Social Science and Humanities Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
ConfiSign HIV Self-Test: Evaluation of Clinical Performance and Usability in the hands of untrained users.
REFNo: HS5545ES

The objective of this study is to evaluate the clinical performance and the usability of the ConfiSign HIV Self-Test in the hands of untrained users from a low prevalence HIV region and having no experience in HIV self-testing (HIVST).
The following specific studies will be conducted:
Part 1: Results Interpretation Study
Part 2: Observed untrained user study

Uganda 2025-02-14 17:33:35 2028-02-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stephen Asiimwe
ID: UNCST-2019-R000059
Clinical Spectrum and Societal Impact of Cognitive Impairment, Alzheimer’s and Related Dementias Among People with HIV in Uganda
REFNo: HS5493ES

1. Determine the prevalence and classification of MCI/ADRDs (1A) and compare trajectories of cognitive performance (1B) between older PWH in Uganda and demographically similar HIV-negative individuals.
2. Identify pathophysiologic contributors to MCI/ADRDs in older adults in Uganda by performing deep phenotyping with novel plasma biomarkers and neuroimaging.
3.Discover and validate novel, multilevel mechanistic models of MCI/ADRDs among older PWH by employing ML methods.
Uganda 2025-02-14 17:30:42 2028-02-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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