Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Mercy Muwema
ID:
ASSESSMENT OF THE QUALITY OF PERINATAL CARE, AND DEVELOPMENT OF AN IMPROVED QUALITY OF PERINATAL CARE MODEL TO REDUCE PERINATAL DEATHS IN BUNYORO REGION
REFNo: HS483ES

Primary Objectives
1.To describe the health facility and health worker structures in place to support perinatal care at district hospitals in Bunyoro region.
2.To assess the prevalence and factors associated with poor quality of perinatal care at district hospitals in Bunyoro region
3.To assess the association between quality of perinatal care and birth outcomes at district hospitals in Bunyoro region
4.To explore care providers and client’s experiences on quality of perinatal care at district hospitals in Bunyoro region
5.To develop a context-specific quality of perinatal care model for Bunyoro region

Secondary objective
6.To assess the feasibility and acceptability of the context-specific quality of perinatal care model

Uganda 2020-02-06 2023-02-06 Medical and Health Sciences Degree Award
Grace Kisitu Paul
ID: UNCST-2024-R004102
DPART STUDY: DIHYDROARTEMISININ-PIPERAQUINE IN THE CONTEXT OF ANTIRETROVIRAL THERAPY
REFNo: HS486ES

OVERALL AIM: To determine the PK/PD of DP in HIV-infected children in the setting of first-line ART regimens including LPV/r, EFV and potentially the integrase inhibitor dolutegravir (DTG) which may become widely used in older Ugandan children.
Our primary objectives are:

PRIMARY OBJECTIVES:

1) To evaluate and compare the PK exposure and safety of single dose DP in HIV-infected children on LPV/r-based ART to HIV-uninfected children not on ART (Group L1 vs C1)
2) To evaluate and compare the PK exposure and safety of 3-dose DP in HIV-infected children on LPV/r-based ART to HIV-uninfected children not on ART (Group L3 vs C3a)
3) To evaluate and compare the PK exposure of 3-dose DP in HIV-infected children on EFV-based ART and HIV-uninfected children not on ART (Group E3 vs C3a).
4) To evaluate and compare the PK exposure of 3-dose DP in HIV-infected children on DTG-based ART and HIV-uninfected children not on ART (Group D3 vs C3b).

SECONDARY OBJECTIVES:

1) The effects of DP on antiretroviral PK in the above 3-dose arms (EFV, DTG, LPV/r and controls)
2) To evaluate the association of anthropomorphic indicators of malnutrition on PK exposure of DP in HIV-infected and HIV-uninfected children
3) Assess auto-induction of DHA from single dose to 3-dose
4) To assess the prevalence of pharmacogenetic variants in key metabolic enzymes, including UGT1A1, CYP2B6, CYP3A4, and ABCB1, and the impact of these variants on ACT and ART PK.


Uganda 2020-02-06 2023-02-06 Medical and Health Sciences Non-degree Award
Margaret Lubwama
ID: UNCST-2019-R000636
Prevalence of multidrug resistant bacteria carriage on mobile phones of final year medical students at Makerere University College of Health Sciences
REFNo: HS491ES

1. To determine the prevalence of multidrug resistant bacteria on mobile phones of final year medical students at Makerere University College of Health Sciences.
2. To determine risk factors associated with multidrug resistant bacteria carriage on mobile phones of final year medical students at Makerere University College of Health Sciences

Uganda 2020-02-06 2023-02-06 Medical and Health Sciences Non-degree Award
Ryoma OTSUKA
ID:
Study on Sustainability of Mountain Gorilla Tourism: From a Tourism Management Perspectives
REFNo: SS387ES

The aim of this study is to contribute to the sustainable development of mountain gorilla tourism in Uganda. We have three main objectives of our study. The first one is to better understand tourist needs or expectations and how it is engendered in relation to information sources. The second one is to better understand and explore factors that affect tourist satisfaction. The third one is to understand rangers’ perception of mountain gorillas, gorilla tourism, and tourists.
Japan 2020-02-06 2023-02-06 Social Science and Humanities Degree Award
Amy Young
ID:
Causes of under-five child mortality in the slum communities of Kampala, Uganda: A Verbal and Social Autopsy Study
REFNo: HS507ES

The study seeks to identify the biomedical causes of death as well as the sociodemographic, behavioral and environmental factors associated with child mortality in the slum communities of Kampala. This includes recognition of illness, decisions around care-seeking, and care-seeking behaviors.
USA 2020-02-06 2023-02-06 Medical and Health Sciences Non-degree Award
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