Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Isabel Larridon
ID:
C3 and C4 Cyperaceae of Uganda
REFNo: NS12ES

The fieldwork is organised in the context of a project looking at the differential impact of climate change of C3 and C4 plant lineages in Africa. C4 photosynthesis is an evolutionary response to climate change (including aridification). Multiple independent origins of the C4 pathway in Cyperaceae provide ideal opportunities to study the differential response of C3 and C4 lineages to climate change. The largest diversity of C4 Cyperaceae lineages occurs in Africa allowing us to investigate C4 evolution within the unique climatic and biogeographical history of the continent. Africa is undergoing aridification at a scale and level that is only comparable to Australia. Studying adaptation mechanisms in African flora may be key to decipher long-term evolutionary response to global warming in plants. In the overarching project, we aim to apply the novel HybSeq technique to acquire 350+ low-copy targets and high-copy genomic loci evolving across a range of rates, combined with access to newly available fossils providing further calibration dates, to obtain an accurately dated and robust Cyperaceae Tree-of-Life, resolve relationships in C4 Cyperaceae lineages and identify their closest sister C3 lineages. Together with model-based biogeographical methods and present-day and paleoclimatic ecological niche models informed by baseline data from Royal Botanic Gardens Kew’s vast collection of herbarium records, this data will provide key knowledge on how C3 and C4 Cyperaceae lineages have differentially responded to environmental pressures in Africa over the last c. 85 Ma. This will allow modelling how they will respond in future and inform conservation actions.
Belgium 2017-04-25 2020-04-25 Natural Sciences Degree Award
David  Coppock Layne
ID:
Climate Change Perceptions and Adaptation Among Small-Scale Farmers in Uganda: A Community-Based Approach
REFNo: SS44ES

\r\n 1.) Determine if small-scale farmers in Uganda perceive the climate to be changing, and if so, determine how and why they perceive it to be changing.\r\n\r\n 2.) Determine what adaptive actions, if any, small-scale farmers in Uganda are taking in response to the changes in the climate they perceive.\r\n\r\n 3.) Determine what resources small-scale farmers in Uganda need to enhance their resilience to climate change. \r\n\r\n 4.) Determine how the climate-change perceptions, adaptive actions, and resource needs vary with the location where small-scale Ugandan farmers reside, particularly between urban and rural locales. \r\n
USA 2017-04-20 2020-04-20 Social Science and Humanities Degree Award
Simon  Sensalire
ID:
A TREND ANALYSIS OF BEHAVIORAL CHANGE AMONG GIRLS AND YOUNG WOMEN IN THE DREAMS PILOT DISTRICTS
REFNo: SS61ES

Generally the study aims at assessing changes in sexual behavior of girls and uptake of HIV related services Specifically, the study aims; 1) To determine girls exposure to the DREAMS behavior change communication package (BCC) 2) To determine changes in knowledge and risk perception of HIV among girls under DREAMS intervention 3) To determine changes in sexual behavior of girls over time 4) To determine levels of contraceptive use among girls/young women 5) To determine the various forms of violence experienced by the girls and the actions taken by the victims 6) To determine the various forms of parental and partner support and how it influences the behavior of the girls? 7) To determine HCT and disclosure among girls who have tested for HIV 8) To assess the influence of DREAMS on the girls behavior over the pilot period
Uganda 2017-04-11 2020-04-11 Social Science and Humanities Non-degree Award
Samson Okello
ID: UNCST-2019-R001580
Polycyclic aromatic hydrocarbon exposures and dietary risk of Esophageal squamous cell cancer in southwestern Uganda
REFNo: HS37ES

1) To evaluate biomass fuel exposure as an ESCC risk factor by comparing personal carbon monoxide exposure among ESCC patients to that of age and gender matched controls with normal esophageal epithelia. We hypothesize that individuals with ESCC have greater exposure to biomass fuel compared to matched age and gender controls. \r\n\r\n2) To assess food preparation methods and dietary patterns as risk factors for ESCC in southwestern Uganda. We hypothesize that patients with ESCC have unique food preparation methods and consumed foods with high polycyclic aromatic hydrocarbons content compared with age and gender-matched controls with normal esophageal epithelia.\r\n
Uganda 2017-03-28 2020-03-28 Medical and Health Sciences Non-degree Award
Simon  Sensalire
ID:
Improving Quality of Care of Maternal and Child Services through Result Based Financing (RBF): A Health Facility Based Case Control Survey
REFNo: HS43ES

ï‚§ To assess whether the RBF payment method, when implemented, improves the quality of ANC, delivery and PNC services compared to usual financing methods ï‚§ To assess health provider perceptions and expectations of whether other services have, or will be impacted by the RBF intervention ï‚§ Assess the effect of RBF on practices of midwives through observing service delivery ï‚§ Determine whether women experience of delivery and PNC services reflect impact of the intervention on quality of MNCH services? ï‚§ To draw lessons about RBF in the context of Uganda and inform RBF rollout strategy? ï‚§ Contribute to learning on improvement strategies for MNCH
Uganda 2017-03-28 2020-03-28 Medical and Health Sciences Non-degree Award
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