Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,731
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Victoria Nankabirwa
ID: UNCST-2021-R011871
Longitudinal Neurodevelopment in a Sub-Saharan Africa Cohort (LONISAC study)
REFNo: HS3405ES

1. To describe brain development (white matter volume, grey matter volume and total brain
volume) trajectories as measured by MRI among typical children from birth to 5 years of age
2. To describe patterns of motor, cognitive, language and social-emotional development among
typical children from birth to 5 years of age
3. To describe patterns of physical growth among typical children from birth to 5 years of age
4. To explore prenatal and postnatal factors associated brain and neurocognitive development
(school readiness) at 5 years of age
5. To describe the association between total white matter volume and the global scale for early
development (GSED) scores
Uganda 2023-12-21 10:17:30 2026-12-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Namakula
ID: UNCST-2022-R006923
Burden of antibiotic use among outpatients at Mulago National Referral Hospital, Uganda.
REFNo: HS3440ES

1. To determine the prevalence of antibiotic prescription among outpatients at Mulago National Referral Hospital, Uganda.
2. To determine the appropriateness of antibiotic prescription among outpatients at Mulago National Referral Hospital, Uganda.
3. To determine the factors associated with antibiotic prescription among outpatients at Mulago National Referral Hospital, Uganda

Uganda 2023-12-21 10:16:27 2026-12-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
Realist Evaluation and Learning in a Multi-country Medical OXYgen Program (REAL-MOXY)
REFNo: HS3444ES

To understand the perspectives of a) patients/caregivers, b) healthcare workers, managers and biomedical engineers/technicians.,To examine how pulse oximetry and oxygen are used by nurses and medical officers, why, and how this impacts on patient care.,To follow patient journeys from arrival through the first 4 hours of care, to understand the sequence of care for acutely unwell children, including how pulse oximetry and oxygen are integrated with other aspects of emergency care.,To map care pathways (as they are intended) for children (<15 years) with four hypothetical clinical scenarios in each participating facility. ,To identify facilities with high and low functioning oxygen systems, based on current pulse oximetry and oxygen-related clinical practices and facility oxygen readiness.,To understand how oxygen and pulse oximetry are used (or not used) at a facility level, and to identify opportunities for strengthening oxygen systems for beneficiaries, users and managers. ,
Uganda 2023-12-21 10:12:51 2026-12-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gertrude Nanyonjo Gawaya
ID: UNCST-2022-R005857
CELEBRATE: Acceptability and Feasibility of bnAbs for Infant HIV Prevention in South Africa and Uganda
REFNo: HS3466ES

1. Understand acceptability and preferences for product attributes and identify factors that influence the adoption of bnAb prevention products for post-natal prophylaxis among healthcare providers, mothers, family members, and community stakeholders.
2. Identify special considerations for administering bnAbs to infants in the post-natal period, including challenges, perceived benefits, and feasibility considerations.
3. Understand key health system and programmatic perspectives including challenges and feasibility of introducing bnAb for post-natal prophylaxis among health service providers and policy makers.

Uganda 2023-12-19 11:29:43 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adrian Muwonge
ID:
Piloting a Digital One Health platform for AMR surveillance
REFNo: HS3391ES

1.Testing the utility of our mobile phone application prototype for harmonizing metadata capture 2. Piloting the use of long-read sequencing of routinely cultured pathogens (Escherichia coli and Klebsiella spp.) 3. Developing a portable and integrated data workflow to feed into our prototype data sharing and analysis web portal 4.Supporting local capacity building through training seminars on long read sequencing and data analysis. The output of this project will allow us to demonstrate and evaluate the feasibility and challenges of integrating One Health as a shared resource
Uganda 2023-12-19 11:27:37 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dennis Ssesanga Ernest
ID: UNCST-2023-R008022
EFFECT OF MHEALTH COMMUNICATION ON STIGMA AND RETENTION IN CARE AMONG YOUTH LIVING WITH HIV AND LINKED TO CARE IN UGANDA.
REFNo: SS2215ES

1. To explore the effect of mhealth communication on stigma among youth living with HIV and linked to care in Uganda.
2. To systematically develop and evaluate an mHealth intervention on stigma and retention in care among youth living with HIV and linked to care in Uganda.
3. To investigate the determinants of stigma and retention in care among youth living with HIV and linked to care in Uganda.
4. To determine the effect of mhealth communication on retention in care among youth living with HIV and linked to care in Uganda.
Uganda 2023-12-19 11:26:33 2026-12-19 Social Science and Humanities Clinical Trial Degree Award
Beatrice Francis Robinah Nassanga
ID:
Factors associated with immunogenicity of tuberculosis vaccines in Ugandan adolescents
REFNo: HS3343ES

1. To determine the impact of baseline infectious exposures and sociodemographic factors on the immunogenicity of BCG revaccination and of candidate TB vaccine “ChAdOx1-85A prime – MVA85A boost” in Ugandan adolescents 2. To characterise the baseline innate immune microenvironment and its impact on the immunogenicity of BCG revaccination and of candidate TB vaccine “ChAdOx1-85A prime – MVA85A boost” in Ugandan adolescents 3. To characterise the baseline T and B cell immune microenvironment and its impact on the immunogenicity of BCG revaccination and of candidate TB vaccine “ChAdOx1-85A prime – MVA85A boost” in Ugandan adolescents
Uganda 2023-12-19 11:23:12 2026-12-19 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
Attitudes and Beliefs Around Smoking Behaviors and Smoking Cessation Among People Living with HIV and Healthcare Providers in Uganda
REFNo: HS3301ES

to understand smoking behaviors and attitudes and beliefs around smoking cessation among PLWH, to mitigate risk factors for cancer in this population. We also seek to explore underlying factors, and perceived facilitators and barriers of smoking cessation among patients and healthcare providers to promote the development of effective smoking cessation interventions for PLWH.
Uganda 2023-12-19 11:21:20 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Wabwire  Oduke Julius
ID:
Inclusion in Universal Primary Education and Outcomes of Learning Disabilities in Wakiso District.
REFNo: SS1957ES

1) To find out the extent to which the mechanism in school climate foster inclusion in UPE and their effect on education outcomes of learning disabilities. ,The purpose of this study is to examine the inclusion mechanisms of school climate and teachers inclusive efficacy using the ecological systems model integrated with the social cognitive theory as determinants of educational outcomes for children with learning disabilities under the universal primary education system.,
Uganda 2023-12-19 11:19:22 2026-12-19 Social Science and Humanities Non-Clinical Trial Degree Award
Winifred Kayizzi Nimukunda
ID:
University governance and research performance in selected public universities in Uganda
REFNo: SS1952ES

The research is to investigate the relationship between university governance and research performance of public universities in Uganda,To examine the impact of participation by university stakeholders in governance decision making processes on research performance of public universities in Uganda.,To investigate the academic governance practices impact on research performance of public universities in Uganda.. ,To establish the effect of governance architecture on research performance of public universities.,
Uganda 2023-12-19 11:16:13 2026-12-19 Social Science and Humanities Non-Clinical Trial Degree Award
Damalie Nakanjako
ID: UNCST-2019-R000383
Training needs assessment for Schistosomiasis research training at academic and research institutions in Uganda
REFNo: HS3446ES

To identify the research training resources, faculty development, scientific environment contributions and administrative processes needed to undertake a research-training program focused on schistosomiasis.,To assess the existing research and research training capacity for schistosomiasis at Makerere University and collaborating institutions (other Uganda universities, Uganda Virus Research Institute and the Ministry of Health vector control division).,The general aim of this project is to assess existing research and research training capacity for schistosomiasis at Uganda institutions,
Uganda 2023-12-19 11:13:21 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martha Namusobya Sarah
ID:
Harnessing machine learning to predict risk of treatment interruption among people living with HIV in Uganda
REFNo: HS3411ES

2. To validate/test the model to assess its performance in predicting risk of TI among PLWH in Uganda,1. To train the model in predicting risk of TI among PLWH in Uganda,To use available Big Data at TASO Uganda to build a ML model that can predict risk of TI among PLWH in Uganda,
Uganda 2023-12-19 11:11:37 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses Ocan
ID:
An analysis of Ugandan Malaria Epidemic Situation and Real-world Effectiveness of Fludora Fusion in Malaria vector control
REFNo: HS3416ES

4. To explore facilitators, experiences of individuals in households and barriers to malaria mosquito vector control using Fludora Fusion in Yumbe district, Westnile region, Uganda. ,3. To evaluate the real-world effectiveness of indoor residual spraying using Fludora Fusion in Uganda using a prospective design. ,2. To determine malaria burden in public and private health facilities in Fludora Fusion exposed (Yumbe district) and non-exposed (Soroti district) settings in Uganda using a retrospective design.,1. To establish through a systematic review and meta-analysis the efficacy of Fludora Fusion and other chemical compounds used in indoor residual spraying for malaria mosquito vector control in sub-Saharan Africa.,To investigate the efficacy of Fludora Fusion against primary malaria vectors, community experiences, and practices regarding indoor residual spraying and the implications on malaria burden in selected districts in Westnile region, Uganda. ,
Uganda 2023-12-19 11:10:14 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
Smart Discharges for Older Children: A Cohort study to develop prognostic algorithms for post-discharge mortality among children over 5 years of age.
REFNo: HS3449ES

• Phase III– To qualitatively assess post-discharge experiences of children 5-<16 years of age admitted for proven or suspected sepsis, and the experiences of their families and health workers providing care.,• Phase II – To quantitatively evaluate health-related quality of life (HRQL) and functional status up to 12 months post-discharge in children 5-<16 years of age admitted for proven or suspected sepsis.,• Phase I – To develop and internally validate a clinical risk prediction model for identifying children 5-<16 years of age admitted for proven or suspected sepsis who are at high-risk of post-discharge death.,To develop and validate the Smart Discharges approach to improve outcomes among all pediatric populations, and ultimately to build a scalable solution for improving post-discharge outcomes. ,
Uganda 2023-12-19 11:07:58 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CHRISTINE KULABAKO TRICIA
ID:
Understanding social perspectives in the management of Brucellosis: The experiences of affected population in Nakasongola district, Uganda
REFNo: SS2223ES

To identify socio-demographic patterns of brucellosis infection in the community.
To examine social factors that influence transmission of brucellosis.
To analyse affected populations' experiences that shape the control of and response to brucellosis.
To explore the effects of brucellosis infection in the community.
Uganda 2023-12-19 11:02:42 2026-12-19 Social Science and Humanities Non-Clinical Trial Degree Award
Sarah Juster
ID: UNCST-2023-R007855
The Role of Trees in Displacement Settings: A Mixed-Methods Approach to Understanding Household-Level Perspectives Among Hosts and Refugees in Northwest Uganda
REFNo: SS2241ES

Conduct research analysis and return findings to participants in the form of a community map and forest product brochure,Conduct transect walks with 120 firewood collection study participants to gauge where and why firewood is collected, and any other important forest products obtained along the way,Conduct sketch mapping with firewood collection study participants for cognitive preparation before embarking on the firewood collection route,Study the experience of firewood collection for 120 refugee and host national participants,Analyze study results to present information to non-governmental organizations and other stakeholders (including the Office of the Prime Minister) on the subjective benefits and experiences of individuals participating in TBIs, and a sub-group of individuals without TBI exposure.,Conduct a mixed-methods Q-Methodology study to improve understanding of participant benefits and preferences as related to TBIs,Recruit 180 participants of three TBIs as well as 60 individuals not involved in TBIs from Imvepi and surrounding villages,Study the household-level impact of Tree-Based Intervention (TBI) participation for 240 refugee and host nationals,
USA 2023-12-19 10:56:31 2026-12-19 Social Science and Humanities Non-Clinical Trial Degree Award
Joan Mutyoba Nankya
ID: UNCST-2021-R010992
Models to link and retain HBV-infected patients into integrated HIV/HBV care in a high HBV burden region of Uganda.
REFNo: HS3163ES

4. To explore motivations, barriers and preferences for timely engagement into HBV care among patients ,3. To measure HBV awareness, prevalence, treatment status and related factors among patients admitted with liver disease in both Arua and Koboko hospitals. ,2. To evaluate effect of the TPS intervention on (i) linkage to integrated HBV/HIV care (ii)HBV treatment and monitoring uptake among patients in care ,To design a “treatment and care-peer support” intervention for HBV patients to be implemented in both the recently integrated HIV/HBV clinics and in the community served by these clinics. ,
Uganda 2023-12-13 12:33:10 2026-12-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Denis Bbosa
ID: UNCST-2021-R012847
Value-Addition to Matooke Peelings to Produce Polyhydroxyalkanoates (PHA) – A Biodegradable Bioplastic
REFNo: SIR252ES

MAIN OBJECTIVE
•To produce PHA using Ugandan Matooke peelings as the carbon source for microbial production of a bioplastic.
SPECIFIC OBJECTIVES
•To determine the optimum conditions in terms of Ph, time, bacteria, and temperature to produce PHA.
•To test the chemical properties of the optimized produced PHA.

Uganda 2023-12-13 12:31:30 2026-12-13 Engineering and Technology Non-Clinical Trial Non-degree Award
Kirsten Beyer M
ID: UNCST-2021-R013472
Preventing Cervical Cancer among Females in Sex Work
REFNo: SS1990ES

Test and refine the intervention iteratively through implementation cycles using the CFIR framework and Plan-Do-Study-Act (PDSA) cycles to identify barriers and solutions for implementation and scale-up,Develop a cervical cancer prevention and control intervention for FSW in Kampala Uganda, using the Consolidated Framework for Intervention Research (CFIR) and supported by a community advisory board (CAB),Describe demographics, risk behaviors, previous HIV/HPV/Cervical cancer screening, knowledge and attitudes among 300 FSW seeking DIC services and document current DIC cervical cancer screening referral practices for these women,The general objective is to develop and test an intervention targeting HPV testing and cervical cancer screening and treatment among FSW seeking services at two DIC in Kampala, Uganda, and compare this new intervention to current practice (questionnaire-based referral to cervical cancer screening) at the DIC,
USA 2023-12-13 12:30:31 2026-12-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
Pablo Sanchez Virosta
ID: UNCST-2023-R006305
Leothreat. Providing ecotoxicological wildlife health services in Uganda
REFNo: NS650ES

Assessing metal exposure in biotic and abiotic portions of the environment, effects of this exposure and trophic transfer. Additionally, we will evaluate establishing biomonitoring programs of other suspected pollutants in Uganda. The final objective of this project is to produce data on the ecotoxicological status of QENP that will allow the local authorities to make informed decisions focused on conservation.
Spain 2023-12-13 12:28:36 2026-12-13 Natural Sciences Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."