Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Adrian Muwonge
ID:
The dynamics of antimicrobial resistance (AMR) genes in the pig and human gut microbiome in Uganda
REFNo: HS103ES

The hypothesis to be tested is that people in contact with pigs in peri-urban settings are at higher risk of acquiring AMR genes across this interface than people in rural settings. The specific objectives are: 1. To identify significant changes in taxonomic and AMR genes in gut microbiomes of people and their pigs in peri urban and rural settings over a one-year period using 16SrRNA, AMR gene probes and real time PCR. 2. To conduct forensic investigations of the significant changes detected in objective 1 using sequence based metagenomics on the corresponding gut microbiomes in parallel with whole genome sequencing and phenotypic AMR testing of sentinel bacteria to understand the underlying dynamics. 3. To predict, estimate and make inferences on AMR gene occurrence, taxa-linked within and between host exchange and their potential phenotypic effects using bioinformatic, statistical and support vector machine approaches on the data generated in 1&2.
Uganda 2017-10-11 2020-10-11 Medical and Health Sciences Non-degree Award
Gladys Tugume T
ID:
Predictors and Outcomes of patients lost to follow-up from HIV care and treatment in Uganda
REFNo: HS130ES

1. To describe outcomes (HIV-related &other death, self-transfers and disengaged from care) of PLHIV LTFU from HIV care and treatment. 2. To describe the change in cumulative incidence of mortality, retention and ART initiation of HIV-infected patients in Pre-ART care after incorporating outcomes of LTFU patients. 3. To describe the change in cumulative incidence of mortality and retention of HIV-infected patients on ART after incorporating outcomes of LTFU patients. 4. To determine predictors of loss to follow-up among PLHIV in HIV care and treatment at Jinja, Lira, Mubende RRH’s. 5. To determine reasons for engagement or disengagement from HIV care and treatment
Uganda 2017-10-11 2020-10-11 Medical and Health Sciences Non-degree Award
Sylvester Onzivua
ID:
Postmortem study on patients with neuropsychiatric manifestations of unknown etiology, nodding syndrome, and other forms of epilepsy who died in Gulu, Kitgum, Lamwo and Pader
REFNo: HS64ES

• Use postmortem examination to determine cause of death in a selected study population. • Use histopathology to describe the post-mortem findings of individuals who die of neuropsychiatric manifestations of unknown origin, NS and other forms of epilepsy in villages with high epilepsy prevalence in Gulu, Kitgum, Lamwo and Pader. • Use histopathology to investigate whether Ov microfilariae are able to penetrate the brain by evaluating histologic tissue for the products of Ov microfilariae
Uganda 2017-10-03 2020-10-03 Medical and Health Sciences Non-degree Award
othiniel musana mambya
ID: UNCST-2019-R001339
Prospective, Single Arm, Pivotal Clinical Trial Designed to Assess the Safety and Effectiveness of the InPress Device In Treating Primary Postpartum Hemorrhage
REFNo: HS92ES

Evaluate the safety and effectiveness of the InPress Device in the control and reduction of primary postpartum hemorrhage.
Uganda 2017-10-03 2020-10-03 Medical and Health Sciences Non-degree Award
Christopher Mayanja Samuel
ID:
Leadership and Gender: Exploring female students’ lived experiences in leadership in Ugandan public University Councils
REFNo: SS117ES

The main research question of the study is: What are the lived leadership experiences of female student leaders who are members of public university councils in Uganda? 1. Who are female student leaders participating in public university councils in Uganda? 2. How do female student leaders who participate in public university councils in Uganda experience their relations with other council members? 3. What challenges (if any) do female student leaders face on public university councils in Uganda? 4. What lessons can be drawn about gender and leadership from the experiences of female student leaders participating in public university councils in Uganda?
Uganda 2017-10-03 2020-10-03 Social Science and Humanities Degree Award
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