Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Mohammed Lamorde
ID: UNCST-2019-R001293
 A PHARMACOKINETIC EVALUATION OF ETONOGESTREL IMPLANT IN HIV-INFECTED WOMEN ON DARUNAVIR VERSUS RIPILVIRINE-BASED ANTIRETROVIRAL THERAPY (DRIVE-I)
REFNo: HS145ES

Primary objective: To compare the PK of ENG (68 mg) contraceptive implant over 6 months in Ugandan HIV-infected women receiving DRV-based ART or RPV-based ART versus historical controls Secondary objectives: (1) To predict the disposition of ENG over the subsequent 2.5 years of intended use through PK modeling of ENG concentrations beyond 12 months of use in HIV-infected women using DRV- or RPV-based ART (2) To describe the PK exposure over 12 months of ENG contraceptive implant in Ugandan HIV-infected women receiving DRV-based ART or RPV-based ART (3) To describe the pharmacokinetics of DRV 12 hours post-dose (C12) and RPV 24 hours post-dose (C24) prior to and during 12 months of combined use with ENG. (4) To describe the safety and tolerability of combined use of DRV/RTV or RPV and ENG during 12 months of combined use. (5) To describe the relationship between ENG concentrations and participant specific covariates including body weight, albumin, sex-hormone binding globulin and pharmacogenetic factors.
Nigeria 2018-01-29 2021-01-29 Medical and Health Sciences Non-degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
 A PHARMACOKINETIC EVALUATION OF LEVONORGESTREL IMPLANT IN HIV-INFECTED WOMEN ON DARUNAVIR VERSUS RIPILVIRINE-BASED ANTIRETROVIRAL THERAPY (DRIVE-II)
REFNo: HS146ES

Primary objective: To compare the PK of LNG (150 mg) contraceptive implant over 6 months in Ugandan HIV-infected women receiving DRV-based ART or RPV-based ART versus historical controls. Secondary objectives: (1) To compare the PK of LNG over 12 months among women receiving DRV-based ART or RPV-based ART versus historical controls (2) To predict the disposition of LNG over the subsequent 4 years of intended use through PK modeling of LNG concentrations beyond 12 months of use in HIV-infected women using DRV- or RPV-based ART (3) To describe the pharmacokinetics of DRV 12 hours post-dose (C12) and RPV 24 hours post-dose (C24) prior to and during 12 months of combined use with LNG. (4) To describe the safety and tolerability of combined use of DRV/r or RPV and LNG during 12 months of combined use. (5) To describe the relationship between LNG concentrations and participant specific covariates including body weight, albumin, sex-hormone binding globulin and pharmacogenetic factors.
Nigeria 2018-01-29 2021-01-29 Medical and Health Sciences Non-degree Award
Charlotte Hawkins
ID:
The Anthropology of Smartphones and Smart Ageing
REFNo: SS141ES

This project will investigate fundamental changes in people’s relationship to age and health associated with the global rise of the smartphone. The aim is to combine an intellectual challenge in understanding the contemporary nature of age and the impact of new media, with an applied challenge to use this knowledge to help make mHealth (mobile health) interventions more effective. mHealth has potential both for helping those with limited access to professional care but also threatens to bypass and undermine professional medical services. Our aim is to complement technology-led mHealth interventions with ethnography-led participatory design, consisting of a three-way collaboration between mHealth professionals, our ethnographically informed team and our informants in the field. We aim to demonstrate how such collaborations can lead to more culturally appropriate mHealth interventions and more effective improvements in people’s lives.
UK 2018-01-29 2021-01-29 Social Science and Humanities Degree Award
Rose Gawaya
ID:
Challenges faced by women’s organisations in the AID space: Case studies in South Africa and Uganda
REFNo: SS90ES

The purpose of the research is to explore how women’s organisations access and utilise development aid. Access and utilisation of development aid impact on how women’s organisations achieve their organisational goals to address problems faced by women. The specific study objectives are to: 1.Determine how women’s organisations define and respond to the development aid space. 2.Identify what functions determine the participation of women in the development aid space. 3.Examine how access and utilisation of development aid contributes to feminist agendas.
Uganda 2018-01-16 2021-01-16 Social Science and Humanities Degree Award
Charles Okuonzi
ID:
Follower Voice Behavior and Leadership Competencies of Owner-managers in SMEs in Uganda
REFNo: SS142ES

The objective of thestudy is to establish the relationship between follower voice behaviour and leadership competencies of Ugandan SME owner-managers. The study is purely academic and shall involve owner-managers from 65 SMEs and 500 of their followers as respondents
 Uganda 2018-01-11 2021-01-11 Social Science and Humanities Degree Award
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