Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Yahaya Gavamukulya
ID: UNCST-2019-R001017
 Green Synthesis and Biochemical Evaluation of Anticancer Activities of Silver Nanoparticles Conjugated Ethanolic Extracts of Leaves of Annona muricata (Graviola)
REFNo: NS43ES

General Objective To undertake green synthesis and biochemical evaluation of anticancer activities of AgNPs-conjugated ethanolic extracts of leaves of Annona muricata (Graviola). Specific Objectives 1. To conduct LCMS analysis of the ethanolic extracts of leaves of Annona muricata and undertake green synthesis and characterization of the extracts’ mediated AgNPs. 2. To investigate the effects of the AgNPs-conjugated ethanolic extracts of leaves of Annona muricata on the biological properties (morphology, migration, growth, and death) of selected cancer cell lines using selected assays. 3. To evaluate the effects of the AgNPs-conjugated ethanolic extracts of leaves of Annona muricata on the transcriptome for expression of cancer associated genes in selected cancer cell lines using RNA-Seq analysis. 4. Evaluation of the in vivo anticancer activities of the AgNPs-conjugated ethanolic extracts of leaves of Annona muricata against chemically induced tumours in mice models.
Uganda 2018-02-13 2021-02-13 Natural Sciences Degree Award
Helen Liebling Jane
ID:
Sexual and Gender-Based Violence and Torture Experiences of South Sudanese Refugees in Northern Uganda: Health and Justice Responses
REFNo: SS126ES

Specific objectives are to:(1) examine the experiences of South Sudanese refugees and impact of Sexual and Gender-Based Violence (SGBV) and torture on their lives (2) analyse reproductive and psychological health,and justice needs of refugees from their own and service providers’ perspectives and (3) evaluate responses to refugees by state justice, health services and key stakeholders.
UK 2018-02-13 2021-02-13 Social Science and Humanities Non-degree Award
Helen Byakwaga
ID: UNCST-2019-R001168
 Study of Newly Diagnosed Kaposi's Sarcoma
REFNo: HS157ES

1) Describe the clinical and laboratory characteristics of HIV-infected patients who develop KS. 2) Determine survival after KS occurrence in both ART-treated and ART-untreated HIV-infected patients.
Uganda 2018-02-13 2021-02-13 Medical and Health Sciences Non-degree Award
Stephen Kyakulumbye
ID:
A framework for developing citizen-centric e-government applications in developing contexts: The design-reality gap
REFNo: IS9ES

To document a feasible participatory design methodology for citizen e-government applications.
 Uganda 2018-02-13 2021-02-13 Social Science and Humanities Degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
 Steady-state pharmacokinetics of efavirenz (Sustiva/Stocrin) 400 mg once daily in the presence of rifampicin and isoniazid (Rifinah or the local generics)
REFNo: HS161ES

Primary Objective: To evaluate the steady-state pharmacokinetics of efavirenz (Sustiva/Stocrin) 400 mg once daily during co-administration with rifampicin and isoniazid (Rifinah or local generic) Secondary Objectives: 1. To assess the safety and tolerability of efavirenz (Sustiva/Stocrin) 400 mg once daily during co-administration with rifampicin and isoniazid (Rifinah or local generic) 2. To investigate the association between genetic polymorphisms in drug disposition genes and drug exposure.
Nigeria 2018-02-06 2021-02-06 Medical and Health Sciences Non-degree Award
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