Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Leela Channer Winstanley
ID: UNCST-2022-R009457
The evolution and maintenance of an interspecific mutualism between warthogs and banded mongooses
REFNo: NS927ES

The objectives are to understand: 1) Individual variation in mongoose and warthog cleaning engagement 2) How mongooses and warthogs signal to each other to initiate cleaning interactions 3) How cleaning behaviour is transmitted within and and between groups 4) Why cleaning behaviour is restricted to certain populations
UK 2025-03-04 19:18:04 2028-03-04 Natural Sciences Non-Clinical Trial Degree Award
Angelina Kakooza-Mwesige
ID: UNCST-2020-R014529
EVALUATION OF THE IMPACT OF THE THREE TIER INTERVENTIONS FOR DISABILITY IN EARLY CHILDHOOD (IDEC) PROGRAMME IN UGANDA
REFNo: HS5596ES

GENERAL OBJECTIVE

The overall aim of this study is to evaluate the impact of the three-tier IDEC model piloted in the two districts of Mubende and Kassanda in Uganda, with a twofold purpose: (1) to improve intervention design and management and (2) to inform decisions about future investment and scale-up by establishing evidence and impact.

SPECIFIC OBJECTIVES.

Primary objectives
1. To determine the coverage of vision screening at 0-3 months and developmental screening at 9 and 18 months in the study sites.
2. To determine the change in functional abilities in children receiving the Tier 2 intervention.
3. To evaluate effects of the individualised (Tier 3) program at regular intervals (at least every 3 months) on child and family functioning, well-being and participation.
Secondary objectives
1. To determine the change in knowledge and skills in parental/caretaker after the Tier 2 interventions.
2. To determine the change in parental/caretaker level of stress after Tier 2 interventions.
3. To determine the change in parental/caretaker level of stress after Tier 3 interventions.

4. To establish the extent to which children with developmental delay and disability Tier 1 are included in ECD programmes
5. To establish the extent to which children with developmental delay and disability tier 2 are included in ECD programmes. (This could be a compliance or fidelity issue
6. To determine how well (fidelity) the health workers provided the Tier 2 and 3 interventions.
7. To determine compliance with Tier 2 and Tier 3 interventions by the caregivers.
8. To determine family satisfaction with all three tiers of the program, including both children that failed and children who passed the screening assessment (Tier I).
9. To determine the costs and cost-effectiveness of the entire program.
10. To assess the likelihood of continuation
Uganda 2025-03-04 13:40:10 2028-03-04 Medical and Health Sciences Clinical Trial Non-degree Award
Apollo Okello
ID: UNCST-2024-R015725
DEBT FINANCING, DEBT MANAGEMENT BEHAVIOR AND GROWTH SUSTAINABILITY OF SMALL AND MEDIUM-SIZED ENTERPRISES IN LIRA CITY
REFNo: SS3676ES

1. To examine the relationship between debt financing and growth sustainability;
2. To establish the relationship between debt management behaviour and growth sustainability;
3. To establish the moderating effect of debt literacy on the relationship between debt financing and growth sustainability;
4. To examine the moderating effect of debt literacy on the relationship between debt management behaviour and growth sustainability;
5. To examine the nature of debt financing terms, debt management behaviour, and growth sustainability
Uganda 2025-03-04 13:32:06 2028-03-04 Social Science and Humanities Non-Clinical Trial Degree Award
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
Optimising dissemination mechanisms for Malaria clinical practice guidelines in the evidence ecosystem. (MARC-SE-MAGIC)
REFNo: HS5591ES

To study different dissemination mechanisms, customized to health care professionals or other end users of clinical practice guidelines.
Uganda 2025-03-04 13:11:00 2028-03-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kayabula  Alex
ID: UNCST-2023-R005649
Leaders' Personality, Leadership Styles, and Employee Retention in Selected Universities in Central Uganda
REFNo: SS3673ES

Specific Objectives

1. To examine the relationship between introversion and employee retention in in selected universities in central Uganda.

2. To investigate the influence of extroversion on employee retention in selected universities in central Uganda

3. To explore the impact of democratic leadership style on employee retention in selected universities in central Uganda

4. To assess the combined effect of leaders’ personality and leadership styles on employee retention in selected universities in central Uganda

5. To analyze the moderating role of work environment on the relationship between leaders’ personality, leadership styles, and employee retention in selected universities in central Uganda.

Uganda 2025-03-04 13:03:54 2028-03-04 Social Science and Humanities Non-Clinical Trial Degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
Antibiotic Resistance Surveillance and Antimicrobial Stewardship Strengthening in the Karamoja Sub-region (ARSK)
REFNo: HS5566ES

2.2.1 To determine the patterns and prevalence of antimicrobial resistance (AMR) in Napak and Moroto districts of Uganda.
2.2.2 To evaluate the knowledge, attitudes, and practices (KAP) related to antimicrobial resistance (AMR), antibiotic use, and antimicrobial stewardship (AMS) among healthcare workers (HCWs), patients, and their caretakers in Napak and Moroto districts.

Uganda 2025-03-04 13:01:32 2028-03-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lorna Atikoro
ID: UNCST-2024-R002527
Improving diagnostics of Antimicrobial Resistance (AMR) in Sub-Saharan Africa- A multicenter project of the COMBAT AMR in Africa network
REFNo: HS5555ES

. To determine the concordance of the point of care tests NG-Test CTX-M MULTI©, NGTest CARBA 5© and NG Test MCR-1© in the diagnosis of extended spectrum beta
lactamases, carbapenemases and colistin resistant bacteria respectively with conventional
phenotypic culture.
• To determine the 28- day clinical outcomes of patients with multi drug resistant gram negative bacteria.
• To identify the mechanisms leading to inconsistent results between the POCTs and
conventional phenotypic culture.
Uganda 2025-03-04 12:23:18 2028-03-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jenny Löfgren
ID: UNCST-2024-R005428
Orthopaedic trauma, infections and cancer care in Uganda - Disease panorama, management and barriers to care
REFNo: HS5535ES

Investigate complication rates after orthopaedic surgery performed in the study hospitals.,To investigate the proportion of patients with traumatic, infectious and malignant orthopaedic conditions that receive surgical versus non-surgical treatment in the study hospitals,The main objective of the study is to study the management and outcomes of a variety of traumatic, infectious and malignant orthopaedic conditions that are common in secondary and tertiary level hospital settings,To identify current health care gaps in the provision of management of traumatic, infectious and malignant orthopaedic conditions in Uganda. ,To investigate barriers and promoting factors to accessing care for pathological fractures ,Identify rates of complications (revision due to malalignment, infection, technical error) from surgery performed in low-resource settings.,Compare patient functional outcomes if the patient is treated non-surgically, treated surgically within 2 weeks of injury or treated surgically later than 2 weeks after the injury.,
Sweden 2025-03-04 11:09:42 2028-03-04 Medical and Health Sciences Non-Clinical Trial Degree Award
Sarah Kiguli
ID: UNCST-2021-R013020
Observational Study to Assess the Incidence of Malaria among Children Living with Sickle Cell Disease in Jinja Regional Referral Hospital Eastern Uganda.
REFNo: HS5583ES

General Objective
To describe the epidemiology of malaria in SCD patients in Uganda.

Specific objectives:
Primary Objective
1. To determine the incidence of malaria cases in SCD patients over a 12-month period.
1. Secondary objectives
2. To determine the incidence of asymptomatic parasitemia aged 6 months -17 years attending Jinja Regional Referral Hospital Sickle Cell Clinic over a 12-month period?.
3. To determine the incidence of submicroscopic parasitemia aged 6 months -17 years attending Jinja Regional Referral Hospital Sickle Cell Clinic over a 12-month period?.
4. To determine the severity of malaria in SCD patients, including the prevalence of WHO-defined severe malaria complications such as cerebral malaria, respiratory distress, and severe anemia aged 6 months -17 years attending Jinja Regional Referral Hospital Sickle Cell Clinic over a 12-month period?.
5. To determine the frequency of sickle cell disease complications associated with a malaria case.
6. To identify temporal patterns in malaria incidence aged 6 months -17 years attending Jinja Regional Referral Hospital Sickle Cell Clinic over a 12-month period
7. To examine the risk and protective factors associated with malaria susceptibility and severity among malaria-infected SCD patients using malaria chemoprophylaxis.

Exploratory endpoints:

8. To investigate and determine the parasite molecular diversity among SCD patients attending Jinja Regional Referral Hospital?
9. To examine and determine the antimalarial parasite drug resistance patterns among SCD patients


Uganda 2025-03-04 10:54:17 2028-03-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HIRALY ASABAHEBWA
ID: UNCST-2024-R016374
A QUALITATIVE STUDY EXPLORING THE EXPERIENCES OF UNIVERSITY STUDENTS LIVING WITH HIV AND COMPLETING A UNIVERSITY-LEVEL QUALIFICATION IN KAMPALA, UGANDA
REFNo: SS3684ES

To explore the experiences of newly HIV-diagnosed university students in Kampala, Uganda ,
Uganda 2025-03-04 10:29:29 2028-03-04 Social Science and Humanities Non-Clinical Trial Degree Award
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