Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Victoria Nankabirwa
ID: UNCST-2021-R011871
A Case Control Study to Assess Effectiveness and Safety of the R21/Matrix M Malaria Vaccine.
REFNo: HS5891ES

1) To assess the Vaccine Effectiveness (VE) of R21/Matrix-M vaccine against
severe malaria caused by Plasmodium falciparum.

2) To assess the Vaccine Effectiveness (VE) of R21/Matrix-M vaccine against
clinical malaria caused by Plasmodium falciparum in high-transmission
perennial areas.

3) To assess if the R21/Matrix-M vaccine recipients are at an increased risk of
death (all-cause).
Uganda 2025-04-25 9:46:49 2028-04-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine Semambo Sempebwa
ID: UNCST-2021-R011977
Evaluation of Welcome Sesame: Inclusion and Belonging for Displaced Learners in Uganda
REFNo: SS3837ES

Objectives:

Main Objective
1. The main objective/ purpose of this study is to examine the effectiveness of the Welcome Sesame Program for Inclusion and Belonging for Displaced Learners in Uganda.

Specific Objectives
1. Objective 1: To Enhance the capacity of early learning settings to support inclusion and belonging for all learners in refugee and migrant-hosting communities.
2. Objective 2: To increase learners’ skills and dispositions towards equitable, inclusive, and pro-social behavior using the perspectives of caregivers/ parent educators, and other stakeholders as a reference.
3. Objective 3: To evaluate the process effectiveness from the perspective of different stakeholders, including partners, parents/ guardians and caregivers/ parent educators, about what is and is not working well under the different units of Welcome Sesame and identify what needs to be further refined prior to implementing subsequent interventions.
Uganda 2025-04-24 12:45:39 2028-04-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Peterson Kikomeko Kato
ID: UNCST-2019-R000881
Ethnicity and Nutritional Status of Children Aged 0-59 Months in Kiryandongo and Kyangwali Refugee Settlement and Host Community
REFNo: HS5885ES

1.To assess the demographic characteristics of Congolese and South Sudanese refugees in Kyangwali and Kiryandongo refugee settlements and those of their host communities 2.To analyse the nutritional status of Congolese and South Sudanese refugee children 0-59 months in Kiryandongo and Kyangwali refugee settlements and those in their respective host communities 3.To analyse the infant and young child feeding practices of Congolese and South Sudanese refugee children 0-59 months in Kiryandongo and Kyangwali refugee settlements and those in their host communities 4. Investigate the influence of ethnicity on nutritional status (wasting and stunting) of Congolese and South Sudanese refugee children 0-59 months in Kiryandondo and Kyangwali refugee settlements 5.To establish the difference in the age of growth faltering between the children of Congolese and South Sudanese aged 0-12 months in Kiryandongo and Kyangwali refugee settlements 6.To establish the difference in the age of growth faltering between the children of Congolese and South Sudanese refugee children aged 0-12 months in Kiryandondo (mainly South Sudanese) and Kyangwali (mainly Congolese) refugee settlements
Uganda 2025-04-24 12:36:55 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Protazio Sande
ID: UNCST-2024-R002344
EXPLORING THE ROLE OF BOARD GOVERNANCE IN ORGANIZATIONAL PERFORMANCE IN PUBLIC AGENCIES WITHIN UGANDA’S MINISTRY OF FINANCE, PLANNING, AND ECONOMIC DEVELOPMENT
REFNo: SS3855ES

The study aims to explore the role of board governance in enhancing organizational performance in selected public agencies under the Ministry of Finance, Planning and Economic Development in Uganda. It will investigate how board structure, board processes, and board practices influences the efficiency, effectiveness, and relevance of these organizations. The Specific Objectives are: 1. To analyze how different board structures impact the overall performance of public agencies. 2. To investigate the specific practices adopted by boards and their effects on the performance of public agencies. 3. To assess how various board processes contribute to the performance of public agencies. 4. To explore stakeholders’ perceptions about the effect of Board governance on Organizational performance.
Uganda 2025-04-24 12:31:19 2028-04-24 Social Science and Humanities Non-Clinical Trial Degree Award
Andrew Seguya Ggunga
ID: UNCST-2025-R018111
Mountain Gorilla Census in the Bwindi and Sarambwe Ecosystem
REFNo: NS955ES

The Mountain Gorilla Census is a survey that has been periodically conducted to determine the
minimum number of individual habituated and non-habituated mountain gorillas in Virunga
Bwindi Landscape. The census of mountain gorillas also helps us to understand the population
dynamics, including changes in gorilla groups composition and sizes as well as solitary males. In
addition, this survey provides the opportunity to determine levels of human disturbance as well as
the status of other large mammals in the landscape. The results from the census enable us to assess
the success of all conservation efforts aimed at protecting mountain gorillas and its habitats, as
well as to ensure that they receive continue attention from the global conservation community.

Uganda 2025-04-24 12:26:12 2028-04-24 Natural Sciences Non-Clinical Trial Non-degree Award
Robert Mugabe
ID: UNCST-2024-R004064
DESIGN OF A FUZZY LOGIC FAULT DETECTION ALGORITHM AND AUTOMATIC PHASE SWITCHING IN ELECTRIC POWER TRANSMISSION
REFNo: NS954ES

1. To develop a model, using ABCD parameters, of a long transmisision line.
2. To obtain Surge impedance loading (SIL) curves for transmission line monitoring and
fault prediction.
3. To develop a fuzzy logic fault detection algorithm.
4. To simulate the developed model and the fuzzy logic algorithm using SIMULINK
Uganda 2025-04-24 12:24:25 2028-04-24 Natural Sciences Non-Clinical Trial Degree Award
BRENDA GATI MIREMBE
ID: UNCST-2021-R013390
Improving Choice and Use of Biomedical HIV Prevention for Women in Uganda: A Couples-Based Approach (CUPID)
REFNo: HS5827ES

Aim 3: To assess CUPID implementation outcomes, and barriers and strategies to address them, to inform the adoption and integration of CUPID to support women’s PrEP uptake and use.,Aim 2: Assess the effectiveness of the CUPID intervention on PrEP uptake, persistence, and use among Ugandan women, compared to PrEP choice delivered to women only.,Aim 1: To refine CUPID intervention content and implementation to support women’s PrEP choice and use in public health settings.,
Uganda 2025-04-24 12:23:21 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pamela Apio Okwir
ID: UNCST-2022-R010419
Acceptability of SMART pill bottle use among children with Rheumatic Heart Disease on oral penicillin prophylaxis in Lango Subregion, Uganda.
REFNo: HS5816ES

1. To assess the acceptability of children with RHD undergoing oral penicillin prophylaxis on use of SMART pill bottles in Lango subregion, Uganda. 2. To explore the perceptions of children with RHD undergoing oral penicillin prophylaxis on the use of SMART pill bottles in Lango subregion. 3. To determine the factors associated with acceptability of SPBs among children with RHD on oral penicillin prophylaxis
Uganda 2025-04-24 12:16:45 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dathan Byonanebye Mirembe
ID: UNCST-2024-R005315
EVALUATING ANTIRETROVIRAL THERAPY TOXICITIES AND SURVEILLANCE PRACTICES IN UGANDA (ART-TOX STUDY)
REFNo: HS5752ES

1. To describe the ART adverse events experienced by people living with HIV in Uganda
2. To determine the incidence and predictors of treatment-limiting toxicity among people living with HIV.
3. To evaluate the perceptions, barriers and facilitators of ART adverse event screening, monitoring, and
reporting in Uganda.
Uganda 2025-04-24 12:12:26 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Timothy Kintu Mwanje
ID: UNCST-2021-R013684
FORMATIVE DEVELOPMENT OF AN AI-DRIVEN CHATBOT FOR PEER SUPPORT AMONG ADOLESCENTS AND YOUNG PEOPLE LIVING WITH HIV IN UGANDA
REFNo: HS5751ES

1) To explore facilitators and barriers across
multiple stakeholder levels for implementation of generative AI chatbots
into HIV peer support initiatives. 2) To generate a contextually relevant
peer support dialogue dataset to guide development of a virtual peer
support chatbot. 3) To create and refine a prototype chatbot for AYPLHIV
peer support informed by stakeholder feedback.
Uganda 2025-04-24 12:06:29 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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