Mohammed Lamorde
ID: UNCST-2019-R001293
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Pharmacokinetic and pharmacodynamic evaluation of etonogestrel dose escalation with efavirenz-based antiretroviral therapy in HIV-infected Ugandan women (DoublET)
REFNo: HS163ES
Primary objective:
To compare the rate of ovulation (by weekly endogenous progesterone at months 3, 6, and 12) when women receive two 68 mg ENG implants (dose-escalated) compared to one 68 mg ENG implant (standard dose) in combination with EFV-based ART.
Secondary objectives:
1. To determine cervical mucus quality (by collecting weekly WHO cervical mucus scores at months 3, 6, and 12) when women receive two 68 mg ENG implants (dose-escalated) compared to one 68 mg ENG implant (standard dose) in combination with EFV-based ART.
2. To compare the PK parameters of two ENG implants (136 mg total) with combined EFV use versus the standard dose 68 mg ENG implant with no ART (historical controls in the same population using the same laboratory1) over 6 months of combined use.
3. To evaluate the safety and tolerability of two ENG implants with combined EFV-based ART use.
4. To describe the relationship between ENG concentrations and participant specific variables, specifically body weight, albumin, sex hormone binding globulin, pharmacogenetic polymorphisms, and ART concentrations.
5. To describe the long term feasibility and tolerability of increased dose ENG (136mg) subdermal implant use in HIV-infected women receiving EFV-based ART after weeks 96 and 144 of combined use.
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Nigeria |
2018-02-21 |
2021-02-21 |
Medical and Health Sciences |
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Non-degree Award |
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Emmanuel Isingoma
ID: UNCST-2019-R001057
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Prevalence of Brucella antibodies in livestock in Karamoja, northeastern Uganda
REFNo: A28ES
1. To determine by district the prevalence of Brucella antibodies in cattle, goats and sheep in Karamoja sub-region
2. To determine the distribution of Brucella antibodies by sex of the different species of livestock
3. To determine the distribution of Brucella antibodies by age of the different species of livestock
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Uganda |
2018-02-21 |
2021-02-21 |
Agricultural Sciences |
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Degree Award |
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Karolina Werner
ID:
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From Statebuilding to Localized Governance: Exploring African governance structures
REFNo: SS56ES
The project focuses on understanding the legal integration of informal/traditional authorities into the governance of states in sub-Saharan Africa. The objective is to better understand the unique systems of governance present on the continent, providing a comparative study of four countries (Uganda, Zambia, Mozambique, Botswana) with varying degrees of integration.
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Canada |
2018-02-13 |
2021-02-13 |
Social Science and Humanities |
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Degree Award |
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Godfrey Zari Rukundo Zari
ID: UNCST-2019-R001500
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Implementation and Adaptation of a Web-Based Clinical Education Program for Mental Health Providers in Uganda
REFNo: HS59ES
The objective of the study is to assess the acceptability and utility a of western-developed online CBT course in advancing knowledge of cognitive-behavioral interventions among staff and graduate students in the department of psychiatry at Mbarara University/Mbarara Hospital in southwestern Uganda. Because this is the first time the course is being offered in this manner in Uganda, it is necessary to first pilot and adapt the training modules to our local setting.
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Uganda |
2018-02-13 |
2021-02-13 |
Medical and Health Sciences |
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Non-degree Award |
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Anna Stadelman Michelle
ID:
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Assessing Lung Function and Quality of Life in Ugandans after Completion of Multi-Drug Resistant Tuberculosis Treatment (ALFU-MDR TB)
REFNo: HS122ES
To evaluate the impact of MDR TB and its treatment on pulmonary
function in survivors of MDR TB.
To establish the impact of MDR TB and its treatment on the quality of life
of MDR TB survivors.
To assess the effect of HIV and MDR TB co-infection on pulmonary
function in MDR TB survivors.
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USA |
2018-02-13 |
2021-02-13 |
Medical and Health Sciences |
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Non-degree Award |
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