Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
molly naisanga
ID: UNCST-2023-R005602
 THE IMPACT OF KNOWLEDGE, PERCEPTIONS AND BELIEFS OF PATIENTS’ ABOUT ANTICOAGULATION AND THEIR ASSOCIATION WITH INTERNATIONAL NORMALIZED RATIO CONTROL IN UGANDA AND SOUTH AFRICA MIXED METHODS STUDY
REFNo: HS609ES

1. To describe the relationship between patients’ beliefs about warfarin and INR control.
2. To explore patients’ knowledge, perceptions and beliefs about warfarin treatment in Ugandan and South African patients receiving anticaogulation.
3. To explore the knowledge, perceptions and practices of Ugandan and South African health care providers about provision of warfarin.

 Uganda 2020-08-24 2023-08-24 Medical and Health Sciences Non-degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
 An open-label, randomized, single intravenous dosing study to investigate the effect of fixed dose combinations of tenofovir/lamivudine or atazanavir/ritonavir on the pharmacokinetics of remdesivir in Ugandan healthy volunteers
REFNo: HS654ES

Primary objectives
1. To assess the safety and tolerability of single intravenous doses of remdesivir in adult healthy volunteers
2. To evaluate the intracellular pharmacokinetics of single dose intravenous remdesivir with or without co-administration of oral fixed-dose combination tenofovir/lamivudine with patients serving as their own controls

Secondary objectives
1. To evaluate the difference in plasma and intracellular pharmacokinetics of intravenous remdesivir among healthy volunteers receiving tenofovir/lamivudine versus healthy volunteers receiving tenofovir/lamivudine plus atazanavir/ritonavir tablets.
2. To generate a population pharmacokinetic model to describe inter-individual variability in intracellular pharmacokinetics of remdesivir

 Nigeria 2020-08-24 2023-08-24 Medical and Health Sciences Non-degree Award
DEUS KAMYA
ID:
In-vitro activity of mycobacteriophages against Mycobacterium tuberculosis biofilms
REFNo: HS774ES

1. To characterize the lytic activity of mycobacteriophages using Mycobacterium smegmatis mc2155 as host bacterium
2. To determine mycobacteriophage host range on a panel of 50 clinical isolates of Mycobacterium tuberculosis
3. To determine the inhibitory and disruptive effect(s) of mycobacteriophages on Mycobacterium tuberculosis-biofilms
Uganda 2020-08-24 2023-08-24 Medical and Health Sciences Degree Award
CATHERINA NAZZIWA
ID:
Perspectives on Genetic Research and Curative Therapies for Sickle Cell Disease
REFNo: SS520ES

The main objective of this study is to assess perspectives of diverse sickle cell disease stakeholders in Uganda regarding participation in genetics research and curative therapies for sickle cell disease, and to identify the related key ethical, social and cultural issues.
Uganda 2020-08-24 2023-08-24 Social Science and Humanities Degree Award
CATHERINE ABBO
ID:
Incorporating mental health and psychosocial support in the Ugandan Police Child and Family Protection Department toll free line to address sexual and gender-based violence (SGBV) complaints.
REFNo: HS791ES

1. To explore the understanding of TFLOs regarding MHPSS needs of complainants of SGBV. 2. To develop and implement a mental health and psychosocial support training for 20 TFLOs working in Kampala and Wakiso Districts. 3. To conduct an evaluation of the training programme among the TFLOs.
Uganda 2020-08-24 2023-08-24 Medical and Health Sciences Degree Award
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