Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
JIMMY SSEMALULU
ID:
PRESCRIPTION PRACTICES AND USE OF LABORATORY PARAMETERS TO MONITOR EFFICACY AND TOXICITY OF ANTIRETROVIRAL THERAPY (ART) AMONG HIV PATIENTS (15YEARS AND ABOVE) AT ART CLINIC IN BUTABIKA NATIONAL PSYCHIATRIC REFERRAL HOSPITAL, UGANDA.
REFNo: HS151ES

STUDY OBJECTIVES General objective To assess prescription practices and use of laboratory parameters to monitor efficacy and toxicity of ART among HIV patients (15 years and above) at ART clinic in Butabika hospital. 1.5.2 Specific objectives 1. To describe pharmaceuticals prescribed for HIV patients (15 years and above) at ART clinic in Butabika hospital. 2. To determine drug drug interactions between ARVs and other medicines prescribed to HIV patients (15 years and above) at ART clinic in Butabika hospital. 3. To identify laboratory parameters used to monitor treatment response and toxicity of ARVs among HIV patients (15 years and above) on ART in Butabika hospital.
Uganda 2018-04-11 2021-04-11 Medical and Health Sciences Degree Award
Laura Bogart
ID:
GAME CHANGERS: A PILOT INTERVENTION TO EMPOWER HIV CLIENTS AS PREVENTION ADVOCATES IN UGANDA (PHASE 2)
REFNo: SS166ES

Primary objectives include: Assessing preliminary intervention effects on: a) protective behavior of the HIV-positive clients (condom use, partner concurrency/number of partners, engagement in HIV care, ART adherence) b) diffusion of prevention messages across the network, as assessed by the content and extent of communication with network members about protective behaviors (condom use, partner concurrency/number of partners, HIV testing, engagement in HIV care, circumcision), HIV disclosure, and HIV stigma
USA 2018-04-11 2021-04-11 Social Science and Humanities Non-degree Award
CHARLES LUGERO
ID:
A global registry to study the demographics, socioeconomic and clinical factors, etiologies, pathophysiology, management, barriers to care, and outcomes of heart failure patients
REFNo: HS144ES

Study 1. Estimate the incident rate of outcomes in HF patients in world Objectives regions and overall, and assess social and lifestyle factors (demographics, socioeconomic variables, clinical risk factors, diet, medication use, and health‐related quality of life), etiologies and variations in treatment patterns that might influence mortality and morbidity. 2. Describe determinants of different HF phenotypes (HFpEF, HFrEF, HF due to valvular disease, ALVD) in these world regions, and their management and outcomes. G‐CHF Protocol Page 3 2016‐09‐26 Version 1.2 3. Describe the potential role of biomarkers (BNP/NT‐proBNP and troponin, as available), related genetic determinants, and their relation to clinical factors, treatments, and type of HF 4. Assess non‐cardiac co‐morbidities at enrolment, their incidence during the study and how they influence outcomes from both cardiovascular and non‐cardiovascular mortality and morbidity. 5. In a sub‐study of approximately 4000‐5000 patients, perform measures of frailty, cognitive and lung function, mental health, adherence to medication, and dietary assessment, with collection of blood and urine samples for central analysis, to further understand the pathophysiologic changes in HF and their relation to outcomes. 6. Describe patient and system barriers to HF care in a global HF population.
Uganda 2018-04-04 2021-04-04 Medical and Health Sciences Non-degree Award
Clémence Bonneaud
ID:
Pant-hoot call in immature chimpanzees
REFNo: NS40ES

We will describe the age at which pant-hoot production starts. We will examine the order in which the four phases of the pant-hoot call develop. For example: is development sequential with the order of the final pant-hoot call, or do later phases (the climax) develop before early ones. We will investigate at what point multiple elements are produced within a call, and whether the sex differences seen in the pant-hoot calls of adults are also seen during development.
France 2018-04-04 2021-04-04 Natural Sciences Degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
 Clinical and genetic factors influencing variability in warfarin dose requirements in Sub-Saharan African patients: An observational study
REFNo: HS164ES

1. To determine demographic and clinical factors that determine individual daily dose requirements for warfarin in Ugandan and South African patients receiving warfarin as part of their routine care 2. To identify ethnic-specific genetic factors influencing individual daily dose requirements for warfarin in Ugandan and South African patients receiving warfarin as part of their routine care
UK 2018-04-04 2021-04-04 Medical and Health Sciences Non-degree Award
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