Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Sylvia Nabukenya
ID: UNCST-2019-R000906
ASSESSMENT OF THE INFORMED CONSENT PROCESS FOR STUDIES INVOLVING GENETIC RESEARCH AMONG PEOPLE LIVING WITH HIV AT THE INFECTIOUS DISEASES INSTITUTE (IDI)
REFNo: HS199ES

1. To assess the adequacy of informed consent documents used for pharmacogenetic research and the collection, storage and future use of human samples. 2. To determine the methods used by researchers to ensure research participants’ understanding during the informed consent process in pharmacogenetic research. 3. To assess the factors that influence participants’ understanding during the consent process in pharmacogenetic research
Uganda 2018-05-04 2021-05-04 Medical and Health Sciences Degree Award
Jenna  Wozniak Marie
ID:
Community Knowledge, Attitudes, and Practices Around Individual Blackfly Control and the Diseases They Transmit in Northern Uganda
REFNo: HS200ES

The objective of this research project is to determine what individual level control efforts are being used to protect against blackfly biting within communities. Although large-scale control efforts have been implemented in onchocerciasis endemic regions, individual level control efforts are not well recorded or understood. Through the use of a KAP (knowledge, attitudes, and practices) survey it is hoped that this will be understood. Demographic data will also be collected to find correlations between knowledge and education level. Future application of this information can be used to either modify existing methods or to suggest personal control methods for communities where onchocerciasis and nodding syndrome are endemic. This project will take place in the district of Kitgum and Lamwo in northern Uganda were both onchocerciasis and nodding syndrome have been observed. Over a five-week period, I will travel to several communities within each district to conduct my survey. The research question of this project is what do individuals in communities where onchocerciasis and nodding syndrome are observed know as well as perceive about blackflies and what practices do they use to prevent blackfly biting?
USA 2018-05-04 2021-05-04 Medical and Health Sciences Degree Award
Pakoyo Kamba Fadhiru
ID:
Elucidating the mechanism of interaction of mycobacteria rhomboid proteases with their specific substrates
REFNo: NS49ES

The goal is to elucidate the mechanism(s) of interaction of mycobacteria rhomboid proteases with their specific native substrates. There are three specific objectives: • To identify the native peptide substrates for mycobacteria rhomboid proteases. • To elucidate the substrate residues essential in interaction with mycobacteria rhomboid proteases. • To elucidate the mycobacteria rhomboid protease residues essential in interaction with their substrates.
Uganda 2018-04-30 2021-04-30 Natural Sciences Non-degree Award
Andrea  Calcagno
ID:
Using Calcaneal Quantitative Ultrasound (cQUS) and urine Retinol Binding Protein to screen HIV-infected cART-treated patients for reduced bone mineral density: a pilot study
REFNo: HS204ES

Primary objective: To compare DEXA and cQUS in predicting reduced BMD in a population of Ugandan HIV-infected individuals on long-term cART. Secondary objective: To assess the prevalence of abnormal RBP/Cr and the correlation between abnormal RBP/Cr and reduced BMD.
Italy 2018-04-30 2021-04-30 Medical and Health Sciences Non-degree Award
Michael Juma
ID:
EXAMINING THE EFFECT OF SERVICE DELIVERY FACTORS ON TIMELY INITIATION OF TUBERCULOSIS TREATMENT WITHIN PRIMARY CARE SETTINGS IN UGANDA
REFNo: HS205ES

The study goal is to examine the association between service delivery factors and timeliness of Tuberculosis treatment initiation within accredited primary care facilities in Uganda. Here service delivery factors are characteristics relating to HF structure and care delivery. The specific aims are: Aim 1: To explore the association between service-delivery factors (structural and care delivery characteristics) and process timeliness (diagnosis time, laboratory turnaround time and treatment initiation time) Aim 2: To measure the association between process timeliness and Tuberculosis treatment initiation Aim 3: Describe perspectives of healthcare workers (in-charges of outpatient departments, heads of clinical teams and heads of laboratories) within each accredited health facility on preventing delays in diagnosis and initiation of Tuberculosis treatment.
Uganda 2018-04-30 2021-04-30 Medical and Health Sciences Degree Award
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