HAKIIMU KAWALYA
ID: UNCST-2025-R020311
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Sickle Cell Modifier Genes Across Diverse Human Populations
REFNo: HS6710ES
1) To profile the most common fetal hemoglobin associated sickle cell disease modifier genes
2) To determine population specific gene expression patterns of fetal hemoglobin associated sickle cell disease modifier genes
3) To characterize inter-population Allele Frequencies of fetal hemoglobin associated sickle cell disease modifier gene variants
4) To analyze selection signals in fetal hemoglobin associated sickle cell modifier genes using human whole genome sequencing data
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Uganda |
2025-11-13 15:27:46 |
2028-11-13 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Isaac Ssewanyana
ID: UNCST-2020-R014336
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Partial Analytical and Clinical Performance Study focusing on Specimen Type Equivalence, Diagnostic Sensitivity and Specificity, and Usability Evaluation of ConfiSign HCV Pro.
REFNo: HS6742ES
3. Qualification of usability for professional use of ConfiSign HCV Pro through a label comprehension study and a results interpretation study which are to be completed by at least 3 laboratory professionals and at least 4 lay providers/healthcare workers.,2. Establish part of the clinical performance (diagnostic sensitivity and specificity) of ConfiSign HCV Pro using capillary whole blood samples.,1. Demonstrate the specimen type equivalence between capillary whole blood, venous whole blood, serum and plasma samples while using ConfiSign HCV Pro.,The general objective of this study is the partial evaluation of both clinical and analytical performance as well as qualification of usability for professional use of the ConfiSign HCV Pro according to parts of WHO TSS-16 (Part 1 - section 1.2.1, Part 2a - sections 2a.1.1 to 2a.1.3, Part 3a - sections 3a.1.1 to 3a.1.2) and CS (Annex I - Part I and Part II and Annex V - Table 2). For further details, see section 7.4.,
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Uganda |
2025-11-07 5:14:01 |
2028-11-07 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Caroline Gotsche Isabelle
ID: UNCST-2025-R021504
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Antenatal syphilis testing in central Uganda - Exploring provider-level factors affecting maternal syphilis testing coverage
REFNo: HS6671ES
1. Mapping the current body of literature of syphilis testing in ANC services.This will allow us to obtain an overview on the current state of syphilis testing among pregnant women in ANC services in Uganda.
2. Understanding impeding and facilitating factors of syphilis testing in ANC services.
Investigating providers` (Health Care Workers (HCW), midwives, nurses and physicians) knowledge of syphilis, and their experiences, perceptions, ideas and interest in syphilis testing will be essential to gain deeper understanding of these factors. Additionally, providers’ interest and ideas on engaging partners in antenatal syphilis testing will be explored to address the issue of re-infection in pregnant women. To gain an overview of a pregnant woman’s journey through the clinic, paying particular attention to how syphilis screening fits into antenatal care clinic observations will be conducted.
3. Exploring syphilis self-testing as a novel syphilis testing strategy in ANC services.
Investigating policy makers`, providers’ and pregnant women’s understanding and interest in the use of syphilis self-testing will be investigated. Whether the use of secondary distribution of self-test kits to partners of pregnant women to enhance partner engagement may be an acceptable approach among pregnant women will be also examined.
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Germany |
2025-11-07 5:12:16 |
2028-11-07 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
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Promoting education and child well-being through the Education for Protection and Well-being model in Sironko and Budaka districts, Uganda: A cluster non-randomised controlled trial (EPW – Study)
REFNo: HS6277ES
4.1 General Objective
The purpose of this study is to assess the effectiveness of the EPW Program on children, caregivers, and teachers.
4.2 Specific Objectives
1. To assess the effectiveness of the EPW program by comparing intervention and control schools in terms of Student social-emotional learning (SEL) practices, Caregiver-child relationships and positive parenting practices and Teachers’ positive classroom management practices
2. To assess the prevalence of secondary outcomes for each participant group
3. To determine implementation factors (e.g., attendance, fidelity) that influence program effectiveness.
4. To establish the level of satisfaction, barriers and facilitators to participation in the program up to endline in intervention group.
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Uganda |
2025-11-07 5:10:34 |
2028-11-07 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Caroline Agabiirwe Noel
ID: UNCST-2025-R020394
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Development and effectiveness of the Better Health media campaign on maternal and child health-seeking behaviours in Uganda.
REFNo: HS6737ES
1. To explore the knowledge, attitudes, and practices among the target audiences related to ANC, PNC, malaria vaccine and diarrhoea management in children.
2. Assess the acceptability of the campaign among the target audience, exploring attitudes of the target audience towards the campaign and mechanisms of campaign impact.
3. Run a controlled quantitative evaluation study to assess the impact of the campaign on knowledge, beliefs, intentions and behaviours related to ANC, PNC and malaria vaccine.
4. To complement the quantitative study with controlled time series analysis of routine DHIS2 data, to examine shifts in trends in treatment seeking, ANC uptake, PNC uptake, and malaria vaccine uptake that may be attributable to the campaign.
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Uganda |
2025-11-07 5:08:21 |
2028-11-07 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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VICTORIA NYAITEERA
ID: UNCST-2021-R011699
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Knowledge, attitudes, practices, and moderators of Competency Based Medical Education: A needs assessment and faculty development in CBME delivery at Mbarara University of Science and Technology
REFNo: HS4973ES
5. To suggest appropriate adjustments to curricula implementation process for fidelity improvement.,4. To determine the moderators (facilitators and barriers) of competency based medical training in post graduate programs,3. To train the faculty involved in postgraduate medical training on CBME implementation.,2. To identify MUST FOM faculty development/training needs for successful CBME implementation.,1. To assess the knowledge attitudes and practices of faculty towards competency-based training in medical post graduate programs at MUST,To improve the fidelity of competency based medical training curricula for postgraduates at MUST by training the faculty in CBME delivery and making faculty training in CBME a MUST institutional priority.,
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Uganda |
2025-11-07 5:06:17 |
2028-11-07 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Elizabeth Igaga Namugaya
ID: UNCST-2022-R011354
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Advancing Health and Leadership: A Wellbeing Toolkit for Women in Anesthesia and Surgery in Uganda
REFNo: HS6633ES
General Objective
To determine the state of wellbeing among the women in the Anesthesia and Surgical
Specialties in Uganda
Specific Objectives
To understand how women in the Anesthesia and Surgical Specialties in Uganda define
wellbeing.
To determine the state of well-being among women in the Anesthesia and Surgical
Specialties in Uganda.
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Uganda |
2025-11-07 5:05:10 |
2028-11-07 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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NANCY MITAKI Bonareri
ID: UNCST-2024-R003431
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Biochemical Studies and Anti-diabetic mechanism of Cucurbita maxima Duchesne (Pumpkin) fruit extracts in diabetic Rats
REFNo: NS970ES
6. Determine the stability, structure’s function, and behavior of the bioactive compounds from the most active fraction of C. maxima and the target proteins,5. Predict interactions between active compounds (ligands) and diabetic target proteins such as Fibroblast growth factor 21 (FGF21), alpha-amylase and alpha-glucosidase.,4. Identify the bioactive components in the most active fraction of C. maxima fruits.,3. Determine the effects of fractions of C. maxima fruit on oxidative stress markers (Superoxide dismutase, Catalase, Glutathione peroxidase, and malondialdehyde) in diabetic rats.,2. Evaluate the effects of fractions of C. maxima fruit on liver biomarkers (Aspartate transaminase, Alanine transaminase, Alkaline phosphatase) and kidney biomarkers (Urea and Creatinine) , and histology of the liver and kidneys in diabetic rats.,1. Determine the effects of fractions of C. maxima fruit on levels of blood glucose, insulin, and activities of serum amylase and histology of pancreatic cells in diabetic rats.,To investigate the biochemical effects and antidiabetic mechanism of Cucurbita maxima Duchesne fruit extracts in diabetic rats.,
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Kenya |
2025-11-07 5:02:42 |
2028-11-07 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
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Beatrice Arwenyo
ID: UNCST-2025-R018319
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Nutrient enriched biochar Fertilizer innovation from agricultural feedstock for climate smart farming. VERSION 2.0
REFNo: NS1046ES
The overall objective of the research is to produce Nutrient enriched biochar fertilizer from agricultural waste as an alternative to synthetic fertilizer.
Specifically, the study intends to:
i) Characterize agricultural waste for their potential use as feedstock
ii) Develop Nutrient enriched biochar Fertilizer from selected agricultural waste
iii) Validate the efficacy of the Nutrient enriched biochar fertilizer in pilot plots
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Uganda |
2025-11-07 5:01:35 |
2028-11-07 |
Natural Sciences |
Non-Clinical Trial |
Non-degree Award |
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Gertrude Nakigozi
ID: UNCST-2025-R022719
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Pregnancy to Protection: Enhancing Vaccine Confidence for Lifelong Family Health
REFNo: HS6734ES
1. Identify factors that influence vaccine confidence among pregnant women and mothers to enhance immunization uptake at the family level, creating a positive ripple effect across the lifespan.
2. Identify opportunities for and barriers to expanding maternal vaccination coverage through evidence-based community focused approaches.
For objective two we will utilize qualitative methods to understand key stakeholder level perspectives on overcoming barriers related to the 3c’s and the acceptability, feasibility, and appropriateness (implementation outcomes, operationalized as defined by proctor et al. (60)) of mass education and vaccination campaigns that reach pregnant women outside of ANC facilities to expand vaccine access and catalyze uptake within the family unit. We will also explore how other routine immunization delivery across the lifespan can be similarly optimized.
Key informant participants will be identified through existing relationships with the MOH (in the case of policy level stakeholders) and community leaders (in the case of traditional birth attendants and village health team members).
|
Uganda |
2025-11-07 5:00:01 |
2028-11-07 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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