Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Adriena De Visser
ID:
Global Health Electives: Ethical Engagement in Building Global Health Capacity
REFNo: SS229ES

Research Question: At sites where the Cumming School of Medicine (CSM) and other international institutions have long-standing collaborations in support of global health electives, what are the relationship dynamics as perceived by stakeholders in sub-Saharan Africa in regards to visiting medical trainee global health electives? Specific Objectives We aim to: 1)Explore and explain perspectives regarding the harms and benefits of global health electives from multiple stakeholders. 2)Explore and explain perspectives on how to create more equitable and mutually beneficial global health electives from multiple stakeholders. The stakeholder perspectives which we plan to include are those at the host site in Mwanza, Tanzania and Mbarara, Uganda: health facility administrators, host physicians, medical officers, nurses, local trainees, patients and/or family members, and a community leader.
Canada 2018-07-26 2021-07-26 Social Science and Humanities Degree Award
David Meya Bisagaya
ID: UNCST-2019-R000837
High Dose AMBISOME on a Fluconazole Backbone for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: A Phase 3 Randomised Controlled Non-Inferiority Trial
REFNo: HS213ES

Primary Objective: To determine whether short-course high-dose L-AmB is as effective as 7-day amphotericin B deoxycholate-based treatment courses (current standard of care) in averting all-cause mortality in HIV-associated CM patients in a phase-III clinical endpoint trial. Secondary Objectives: 1. To determine the EFA in both treatment arms. 2. To examine the proportions of patients in each arm with clinical and laboratory-defined grade III/IV adverse events; median % change from baseline in laboratory defined parameters, by treatment arm. 3. To determine health service costs by treatment arm. 4. To determine all-cause mortality within the first 2 and 4 weeks. 5. To determine whether short-course high-dose L-AmB is superior to 7-day amphotericin B-based treatment courses (current standard of care) in averting all-cause mortality. 6. To determine rates of cryptococcal relapse / IRIS within the first 10 weeks by treatment arm. 7. To determine rates of disability at 10 weeks by treatment arm.
Uganda 2018-07-26 2021-07-26 Medical and Health Sciences Non-degree Award
David Meya Bisagaya
ID: UNCST-2019-R000837
Operational Research for Cryptococcal Antigen Screening (ORCAS) of HIV Patients: Evaluation of clinical and immunological predictors of outcomes.
REFNo: HS214ES

To identify incidence and risk factors for meningitis or death in asymptomatic CrAg+ persons before 6-months.
Uganda 2018-07-26 2021-07-26 Medical and Health Sciences Non-degree Award
Josephine Kayaga Nsubuga-Mugoa Kayaga
ID:
Successful Strategies for Using Knowledge Management in Small- and Medium-Sized Enterprises (SMEs)
REFNo: SS228ES

The purpose of the research study is to explore strategies that some SMEs managers use to effectively integrate Knowledge Management (KM) into their business practices; with the objective that the research study will enable me to make a contribution to positive social change as the findings from this study may be helpful in expanding opportunities for employees to learn new skills and knowledge. Another contribution to positive social change may be the expansion of employment opportunities because, as SMEs integrate KM into their business practices, SMEs may become more successful, leading to the expansion of employment opportunities.
Uganda 2018-07-26 2021-07-26 Social Science and Humanities Degree Award
Julia Dickson-Gomez
ID: UNCST-2019-R000775
The Social Context of Substance Use and HIV Risk in Kampala City, Uganda
REFNo: SS227ES

To conduct formative research to assess drug use in individuals living in Kampala and the associated contextual factors (drug use sites, sexual and drug networks) that may contribute to HIV injection and sexual risk behaviors.
USA 2018-07-26 2021-07-26 Social Science and Humanities Non-degree Award
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