Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Andrew Tusubira Kuguminkiriza
ID: UNCST-2021-R014026
 Redefining selfcare among people living with HIV: perceptions and practices of HIV and co-morbidity in Uganda.
REFNo: HS3639ES

To understand how persons living with HIV and chronic comorbidities experience and interpret selfcare, in order to redefine selfcare in the Ugandan context.

Specific objectives:
1. To explore the self-care practices of persons living with HIV for managing hypertension or diabetes comorbidities in low-and-middle income countries.
2. To explore how people living with HIV with hypertension and/or diabetes, enrolled in care in Uganda, interpret looking after themselves and their health in their daily lives (selfcare).
3. To determine treatment and heath maintenance practices adopted by people living with HIV and hypertension and/or diabetes enrolled in care in Uganda.
4. To examine the capacity and support for self-care among persons living with HIV and hypertension and/or diabetes enrolled in care in Uganda.

 Uganda 2024-01-25 16:08:26 2027-01-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Elizabeth Ayebare Ombeva
ID: UNCST-2020-R003666
 Evaluation of a multicomponent intervention to improve perinatal bereavement support for women and families after stillbirth and neonatal death in Kenya and Uganda: A pragmatic cluster randomised controlled trial.
REFNo: HS3205ES

To explore factors influencing future scale up and sustainability of the intervention ,To explore potential mechanisms of impact of the intervention through understanding womens’, families’, health workers’ and service managers’ views and experiences of the intervention and usual care after stillbirth and neonatal death,To evaluate whether the intervention was implemented as intended during the trial by assessing fidelity, ‘dose’, reach and adaptations made in the study context. ,To assess the cost effectiveness of the intervention from the perspective of the local health systems in Kenya and Uganda ,To assess the mediating effect of perceived social support on intervention impact. ,To assess the impact of the intervention on maternal anxiety, risk of depression and development, diagnosis, and treatment of mental health conditions.,To assess the effectiveness of the co-produced multicomponent interventions in reducing perinatal grief intensity at 8-12 weeks post birth for women who have experienced stillbirth or early neonatal death. ,
 Uganda 2024-01-24 23:23:30 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mary Nyantaro
ID: UNCST-2023-R006533
 Knowledge, Perceptions and Practices of Parents, Community Members and Health workers on Unclassified Sudden Infant Deaths in Uganda.
REFNo: HS3465ES

This study aims to assess the knowledge, perceptions and practices of parents, community members and health care workers on USIDS in the community in Uganda.
1. To determine the knowledge, perceptions and practices of parents and community members on unclassified sudden infant death syndrome in Uganda.
2. To determine the knowledge, perceptions and practices of health workers on unclassified sudden infant death syndrome in Uganda.
 Uganda 2024-01-24 23:17:54 2027-01-24 Medical and Health Sciences Non-Clinical Trial Degree Award
Ronald Kisekka
ID:
SOIL MICROBIOTA-MEDIATED DISEASE TOLERANCE IN ROBUSTA COFFEE AGROFORESTRY SYSTEMS IN UGANDA
REFNo: NS709ES

To enhance the sustainability of robusta coffee agroforestry systems based on the optimization of plant microbiota interactions for improving coffee response to common diseases in Uganda. ,4. To determine the impact of drought on interactions among soil microbiota, coffee, and pathogens (greenhouse conditions).,3. To evaluate the effects of different soil microbiota composition (shade tree rhizosphere -derived) on the growth and tolerance of coffee trees to major diseases (greenhouse conditions).,2. To determine the extent of influence of shade trees on the soil microbiota associated with robusta coffee (field conditions). ,1. To characterize the soil microbial diversity associated with shade trees and coffee trees in robusta coffee agroforestry systems (field conditions).,
 Uganda 2024-01-24 23:15:17 2027-01-24 Natural Sciences Non-Clinical Trial Degree Award
Fatumo  Segun Adeyemi
ID:
A single-cell quantitative trait map for peripheral blood in the Ugandan population
REFNo: HS3105ES

The overarching aim of this work is to shed light on the mechanisms that genetic variation affects celltype specific gene expression in peripheral blood mononuclear cells (PBMCs) in the Ugandan population for the first time. The key objectives are: 1. Construct a cell-type specific molecular map of PBMCs in Ugandan population
2. Identification of dynamic allelic effects across PBMCs’ lineages
3. Elucidate causality of cell-type specific genetic variants for cardiometabolic traits and diseases in Uganda
population
 UK 2024-01-24 23:07:48 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 Myocardial Fibrosis and Steatosis Burden and Region-Specific Predictors of Progression among ART-treated Women with HIV infection in sub-Saharan Africa (The MUTIMA study)
REFNo: HS3606ES

2. To quantify myocardial steatosis burden and identify hormonal/metabolic predictors of progression among ART-treated WWH in SSA,1. To characterize myocardial fibrosis burden and identify novel infectious/immunologic predictors of progression among ART-treated women with HIV in SSA. ,
 Uganda 2024-01-24 23:01:55 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Arthur Bagonza
ID:
ASSESSING THE BURDEN AND UNDERSTANDING THE CONTEXT OF LYMPHOEDEMA IN UGANDA: A PREVALENCE STUDY AND SITUATION ANALYSIS
REFNo: HS3713ES

2. To conduct a stakeholder analysis in order to gather essential data for the development of effective lymphoedema treatment and care interventions at both primary and secondary healthcare levels in Buvuma and Napak districts of Uganda. ,1. To determine the prevalence of lymphoedema in Buvuma and Napak districts of Uganda,To determine the burden and context of lymphoedema in Uganda,
 Uganda 2024-01-24 22:55:44 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Household Energy Related Burns Study - Burden and Context Evaluation in Hospital Settings in Uganda (CLEAN-Air (Africa) HERBS)
REFNo: HS3614ES

1. To conduct a retrospective review of hospital records (up to 5 years) to determine the burden of household fuel-related burns and their short-term impacts on affected individuals in Uganda.

2. To conduct a survey to examine the occurrence , severity and determining the circumstances of hospital treated burns caused by household energy use in a study period of 24 months, using the WHO Burn Registry data collection form.

3. To conduct a qualitative study gaming health care workers on knowledge, attitudes and practices of burns care including data collection of burn-related cases

 Uganda 2024-01-24 22:50:16 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Kisaakye
ID:
Feasibility of Routine Screening for Sexual Violence Against Children in Humanitarian Contexts in Uganda
REFNo: SS2265ES

The goal of the study is to expand the access of children/adolescents experiencing sexual violence to comprehensive sexual violence services in refugee settings in Uganda. The study’s specific objective is to assess the feasibility of adapting and implementing a multi-faceted screening intervention to expand such access.
Uganda 2024-01-24 22:46:56 2027-01-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Newton Edward
ID: UNCST-2023-R006537
 Study of Genomic Integrity and Safety of Stem-Cell Gene Therapy in Cohorts in Africa.
REFNo: HS3660ES

The overall aim of this research is to establish safe and accessible gene therapies for sickle cell disease by comparing and contrasting cohorts in Africa to the data already obtained from the USA and UK thus establishing a more accurate authentic dataset. We hypothesise that patients with SCD may have elevated somatic mutation rates as compared to healthy non-SCD individuals and that the mutational processes driving the acquisition of these genetic lesions are varied from individual to individual.
 UK 2024-01-24 22:45:26 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Harriet Ajilong
ID: UNCST-2022-R005889
 Assessing Vitamin D serum levels in HIV-positive adolescents 10-19 years with depression in Northern Uganda
REFNo: HS3454ES

To determine the burden of depression in HIV-positive adolescents at Gulu RRH,To assess for serum Vitamin D levels in HIV Positive adolescents 10-19 years with depressive symptoms in Gulu Regional Referral Hospital Methods,
 Uganda 2024-01-24 22:30:43 2027-01-24 Medical and Health Sciences Clinical Trial Non-degree Award
Mercy Kainobwisho Kyomugasho
ID:
AN ANALYSIS OF THE BARRIERS TO PROTECTION AND COMMERCIALIZATION OF TRADEMARK ASSETS BY SMES IN THE NON-ALCOHOLIC BEVERAGE MANUFACTURING S IN UGANDA.
REFNo: SS2153ES

specific objectives of the study are to;
i. To investigate the relationship between trademark protection, licensing, valuation, collaterisation and commercialisation by SMEs in the non- alcoholic beverages in the manufacturing sector.
ii. To identify the barriers to protection, licensing, valuation and collateralisation of trademarks by SMEs in the manufacturing sector.
iii. To examine the legal and institutional framework for protecting, licensing, valuation and collateralisation of trademarks in Uganda.
iv. To propose effective ways for enhancing the protection, licensing, valuation and collateralisation of trademarks by SMEs in the manufacturing sector in Uganda

 Uganda 2024-01-23 18:58:37 2027-01-23 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph Rujumba Rujumba
ID: UNCST-2022-R011160
 Combining monthly dihydroartemisinin-piperaquine and azithromycin for the post-discharge management of children with severe anaemia in Malawi, Kenya, and Uganda: Post-Discharge Malaria Chemoprevention -PDMC-II (acceptability and feasibility sub-study)
REFNo: HS3669ES

2)Explore perspectives of health care providers and caregivers on the feasibility of implementing PDMC with DP + AZ in children diagnosed with severe anaemia in Malawi and Uganda and generate insights for successful integration and scalability of PDMC with DP+AZ in resource-limited settings.,1)To assess health care provider and caregiver acceptability of PDMC with DP + AZ in children with severe anaemia at Malawi, Kenya, and Uganda trial sites. ,To determine the acceptability and feasibility from the health provider and patient/guardian perspective of delivering or receiving dihydroartemisinin-piperaquine (DP) and azithromycin (AZ) for the post-discharge management of children with severe anaemia in Malawi, Kenya, and Uganda.,
 Uganda 2024-01-23 18:57:41 2027-01-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jane Nabwowe -
ID:
ALLELE FREQUENCY DATABASE FOR 21 SHORT TANDEM REPEATS IN THE UGANDAN POPULATION
REFNo: NS716ES

To establish the Ugandan population Y-Chromosome haplotype frequency database,To develop Ugandan population specific 21 autosomal STR markers and Y- chromosome haplotype markers allele frequency data ,To determine population genetic homogeneity among the selected tribes in Uganda ,To determine the genetic diversity of the 21 STRs in a Ugandan population by calculating the forensic and paternity efficiency parameters ,
 Uganda 2024-01-23 18:56:08 2027-01-23 Natural Sciences Non-Clinical Trial Non-degree Award
MARY AJIKO MARGARET
ID:
Prevalence of Paediatric burn injuries Admitted to a hospital in Teso sub-region Eastern Uganda: lessons for prevention
REFNo: HS3484ES

The main objective of this study is to investigate the causes, characteristics, patterns, geographic determinants of paediatric burns and identifying the barriers and enablers to their prevention in a home. Specific Objective of the Study 1. To examine the typical patterns and causes of paediatric burn injuries leading to hospitalization. 2. To establish care givers’ understandings of the injury to their children, considering both injury determinants and preventive means. 3. To assess the effects of various characteristics of the living area on paediatric burn injuries. 4. To determine the enablers and barriers to the creation of safe environment, the implementation of safe practices and the use of products that control or prevent childhood burn injuries in the home.
Uganda 2024-01-23 16:58:07 2027-01-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Margaret Mangheni Najjingo
ID:
Women empowerment, normative influence and project outcomes in Central Uganda
REFNo: SS1942ES

To identify factors that influence women’s economic empowerment within farming communities.

To explore the community construction of femininities and how it influences women’s economic empowerment within agricultural project intervention areas.

To explore the community construction of masculinities and how it influence women’s economic empowerment within agricultural project intervention areas

To find out the factors that influence women’s economic empowerment and household food security within agricultural project intervention areas

 Uganda 2024-01-22 11:38:01 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 EFFECTIVENESS OF THE PARTNER-LED IMPLEMENTATION IN IMPROVING DIGITAL PAYMENT AND CAMPAIGN QUALITY DURING THE YELLOW FEVER CAMPAIGN IN UGANDA: AN EXPLORATORY STUDY
REFNo: SS2221ES

To determine gender norms and relations and their influence on health workers’ response to payment systems (cash vs mobile money) and how these affect the health workers’ performance and motivation in yellow fever vaccination campaigns,To explore the effect of implementing a partner-led digital payment system on the Motivation, Satisfaction, and performance of vaccination campaign health workers,To establish the vaccination coverage of yellow fever in different geographies (equity),To document partner-led implementation process of the Yellow Fever Mass Vaccination campaign,To assess the effectiveness of partner-led Yellow Fever campaign and its effect on digital health worker payments and campaign coverage in Uganda.,
 Uganda 2024-01-22 11:26:43 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 OUTCOMES OF PEDIATRIC PATIENTS DIAGNOSED BY MORPHOLOGY ALONE VERSUS FLOW CYTOMETRY PLUS MORPHOLOGY: A RETROSPECTIVE STUDY
REFNo: HS3352ES

To compare the treatment outcomes between patients diagnosed with the help of flow cytometry with those diagnosed without the help of flow cytometry.,To determine the accuracy of diagnosis of acute leukemia between patients diagnosed with the help of flow cytometry with those diagnosed without the help of flow cytometry.,To assess the time to treatment initiation among patients diagnosed with the help of flow cytometry and those diagnosed without the help of flow cytometry,
 Uganda 2024-01-22 11:25:41 2027-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Using Video-Enhanced Teaching to Increase Maternal Participation in Neonatal Hospital Care
REFNo: SS2030ES

3. To evaluate by survey the perspectives of healthcare workers on their availability to devote to video-assisted maternal education in a neonatal hospital unit in Uganda.,2. To identify maternal and/or neonatal factors that impact the amount of time needed to train mothers to weigh their baby, assess for danger signs, and track feeds using video-assisted teaching.,1. To determine the mean nursing time required to train mothers to perform three specific tasks: (1) weigh their baby, (2) assess for danger signs, and (3) track feeds when facilitated by video-assisted teaching.,The purpose of this study is to evaluate a video that teaches mothers how to monitor their baby in a neonatal hospital unit in Uganda. This is with the goal of reducing the amount of time healthcare workers need to spend teaching mothers and ultimately improving the quality of care that sick and small newborns receive in the hospital. ,
 Uganda 2024-01-22 10:45:51 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Grace Kebirungi
ID:
A QUALITATIVE STUDY ON THE CAUSES OF SLOW ADOPTION OF VIRTUAL REALITY IN MEDICAL EDUCATION IN KAMPALA, UGANDA
REFNo: SIR261ES

Primary objective: To assess the causes of slow adoption of VR in medical education in Kampala ,Uganda Secondary objectives: 1. To identify perceptions of medical students, interns, lecturers at Makerere School of Medicine, doctors and medical association leads in Kampala towards use of VR in medical education. 2.To assess the VR programming capacity in Kampala, Uganda 3 To identify key policy guidelines that would empower VR in Uganda.
Uganda 2024-01-11 13:14:59 2027-01-11 Engineering and Technology Non-Clinical Trial Non-degree Award
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