Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Gladness Mtango E
ID: UNCST-2025-R017177
 The Nurses’ Perception of Their Immediate Supervisors’ Servant Leadership Behaviors and Their Sense of Work Effectiveness in Selected Ugandan Public Hospitals
REFNo: SS4419ES

•To explore the relationship between nurses’ perception of servant Leadership and their perceived access to work information such as willingness to share information.,•To determine the relationship between nurses’ perception of Servant Leadership and their perceived access to work resources such as needed equipment and materials.,•To explore the relationship between nurses’ perception of Servant Leadership and their perceived access to work opportunities such as challenging work and opportunities to learn new skills.,To explore if there are differences in job outcomes due to differences in the sizes of hospitals or the tenure of the nurse employee.,To survey and explore the perception of the nurses in the selected public hospitals in Uganda to determine if there is a relationship between their immediate supervisor’s servant leadership behavior and their job outcomes,
 USA 2025-11-21 14:16:50 2028-11-21 Social Science and Humanities Non-Clinical Trial Degree Award
BANGIRANA SEPHAS
ID: UNCST-2025-R020094
 USAGE OF PATIENT RECORDS MANAGEMENT SYSTEM, PSYCHOSOCIAL WORK ENVIRONMENT, WORK TEAM STABILITY, HEALTH CENTRE CHARACTERISTICS, AND QUALITY OF HEALTH CARE IN HEALTH CENTRE IVS IN SOUTH WESTERN UGANDA
REFNo: SS4395ES

General Objective
The aim of the study is to examine the relationship between usage of patient records management system, psychosocial work environment, work team stability, and the quality of health care in HC IVs in South Western Uganda, with health centre characteristics as a moderating variable.
Specific Objectives
i. To establish the relationship between usage of patient records management system usage and the quality of health care among the HC IVs in South-Western Uganda.
ii. To examine the relationship between psychosocial work environment and the quality of health care at HC IVs in South-Western Uganda.
iii. To assess the relationship between work team stability and the quality of health care HC IV in South-Western Uganda.
iv. To examine the combined effect of patient records management, psychosocial work environment, and team stability on the quality of health care at HC IVs in South-Western Uganda.
v. To assess the moderating effect of health centre characteristics in the relationship between psychosocial work environment and quality of health care in HC IVs in South Western Uganda.
 Uganda 2025-11-21 14:13:43 2028-11-21 Social Science and Humanities Non-Clinical Trial Degree Award
Jackson Mukonzo
ID: UNCST-2021-R013916
 Safety of COVIDEX™ Therapy in adults: in Uganda: A randomized controlled open- label phase 1 clinical trial.
REFNo: HS6540ES

Overall aim
To validate the safety of COVIDEX™ therapy in adult Ugandans.

Specific objectives
Primary objective
To evaluate and document adverse events associated with COVIDEX™ among adults
in Uganda.

Secondary objective:
To determine the plasma concentration of berberine in adults receiving COVIDEX™ at
three different dose levels.
Uganda 2025-11-21 14:11:01 2028-11-21 Medical and Health Sciences Clinical Trial Non-degree Award
William Worodria Ofuti
ID: UNCST-2022-R010915
 Candidate Clinical Correlate as Prognostic Outcome for TB (C3PO) Study
REFNo: HS6545ES

Our specific aims are: 1. To evaluate end-of-treatment (EOT) biomarkers as predictors of recurrent TB 2. To evaluate novel cough and activity biomarkers as predictors of post-TB lung health
 Uganda 2025-11-21 13:53:39 2028-11-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Doreen Rubatsimbira Katangaza
ID: UNCST-2024-R004595
 Social economic determinants of energy poverty at household level in Uganda
REFNo: SS4062ES

To what extend do socioeconomic factors determine energy poverty?
What are the energy poverty hotspots in Uganda?
What are the socioeconomic conditions of the most vulnerable households to energy poverty?
 Uganda 2025-11-21 13:49:30 2028-11-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
DANIEL ELAMU
ID: UNCST-2025-R020928
 PREVALENCE OF MALARIA AND HIV IN UGANDAN CHILDREN WITH TRAUMATIC BRAIN INJURY; AN EARLY OUTCOME STUDY.
REFNo: HS6781ES

Primary objective: To determine the prevalence of malaria (by RDT and PCR) and HIV among children presenting with traumatic brain injury at Mulago National Referral Hospital in 8 months.
Secondary Objective: To assess the impact of malaria parasitemia and/or HIV co-infection on short-term functional recovery, measured by Health-Related Quality of Life (HRQoL) at one-month post-discharge.
Uganda 2025-11-21 13:47:46 2028-11-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
 A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis in Women
REFNo: HS6565ES

To evaluate the efficacy of MK-8527 qm compared to FTC/TDF qd for the prevention of HIV-1 infection as assessed by the incidence rate per year of adjudicated HIV-1 infections To evaluate the safety and tolerability of MK-8527 qm compared to FTC/TDF qd.
 Uganda 2025-11-21 11:18:30 2028-11-21 Medical and Health Sciences Clinical Trial Non-degree Award
Francis Ssebiryo
ID: UNCST-2019-R001250
 Mid-Term Evaluation for the Stand Up for Sexual and Reproductive Health Rights Project
REFNo: SS4574ES

To establish a midline value for key performance indicators outlined in the project’s Performance Measurement Framework(PMF), allowing for a direct comparison with the baseline data. To assess progress toward the Outcome Indicators. To establish a midline value for tracking progress against these outcome indicators, as detailed in the project’s Performance Measurement Framework (PMF). To provide recommendations for strategic project improvements
 Uganda 2025-11-19 8:42:04 2028-11-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eddy Walakira Joshua
ID: UNCST-2022-R009077
 MULTI-COUNTRY OPERATIONAL RESEARCH ON NEW AND EVOLVING FORMS OF VIOLENCE AGAINST WOMEN AND GIRLS LIVING WITH HIV IN UGANDA, KENYA AND TANZANIA
REFNo: SS4545ES

Aim
To conduct a multi-country operational research that examines how new and evolving forms of violence against WLHIV affect their participation in leadership and collective organising within feminist movements in Uganda, Kenya, and Tanzania.

Specific objectives
1.To assess the lived experiences of WLHIV regarding new and evolving forms of violence, and their impact on participation, leadership, and collective organising within feminist movements in Uganda, Kenya, and Tanzania.
2.To examine the experiences of WLHIV who seek or do not seek assistance after experiencing violence, including their access to shelters and support services, and how these factors influence movement-building participation and their advocacy.
3.To analyse, by root cause, how existing barriers hinder WLHIV from receiving assistance and participating meaningfully in coalition-building, advocacy spaces, and feminist leadership.
4.To generate feminist, practice-based evidence and approaches to strengthen inclusive coalitions, leadership pathways, and evidence-informed advocacy under the THRIVE Project at regional levels.
 Uganda 2025-11-19 16:37:11 2028-11-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
Mary Kaakyo
ID: UNCST-2025-R019146
 Impact of Differentiated Service Delivery (DSD) Approaches on Viral Suppression and Retention in Care among Adolescents Aged 10-19 Living with HIV in Masaka Region, Uganda
REFNo: HS6682ES

1.Determine the impact of the DSD approaches on viral suppression and retention in care among adolescents aged 10-19 living with HIV in the Masaka region. 2.Explore mechanisms and pathways through which DSD approaches have impacted (or not) viral suppression and retention in care among adolescents aged 10-19 years living with HIV in the Masaka region and the contextual factors that influence these pathways. 3.Estimate the incremental cost-effectiveness of DSD approaches on viral suppression and retention in care among adolescents aged 10-19 years living with HIV in Masaka region.
 Uganda 2025-11-13 17:13:46 2028-11-13 Medical and Health Sciences Non-Clinical Trial Degree Award
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