Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
The Trends in Clinical Presentation and Management of Diseases among Adults attending Kiruddu National Referral Hospital, Kampala: Review of Medical Records.
REFNo: HS1030ES

General objective
To analyse medical records for trends in presentation and management of disease conditions in the in-patient department (IPD) and out-patient department (OPD) at KNRH from 2019 to date.
Specific objectives
I. To describe trends of respiratory disease presentation and clinical management among adult patients presenting to the IPD, medical and general OPD at KNRH during the study period (January to July 2020) compared to the baseline period (January to July 2019)
II. To explore for any collateral effects of the global SARS-CoV-2 pandemic on chronic disease presentation and management at KNRH during the same study period.

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
AN ASSESSMENT OF THE IMPACT OF COVID-19 ON RMNCAH AND HIV SERVICE DELIVERY AND UTILIZATION IN UGANDA
REFNo: HS1084ES

1. To document the response actions for mitigating the impact of COVID-19 on RMNCAH and HIV services at national, sub-national, health facility and community levels
2. To assess the district, health facility and community preparedness to provide RMNCAH and HIV services during the pandemic.
3. To obtain information on the implications of COVID-19 on the level of access and utilization of routine RMNCAH, HIV and other health services
4. To explore the effects of COVID-19 pandemic on mental health, intimate partner violence and gender roles
5. To assess the effects of COVID-19 on early child development, food security, feeding practices and nutrition among children under five years.
6. To generate recommendations for informing future national policy and public health response to health emergencies

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Bonnie Fournier
ID: UNCST-2019-R000250
Reducing HIV-related Stigma in School Children
REFNo: HS510ES

Specific research objectives:
● Objective 1: To assess the magnitude of change, among young people who receive the arts-based intervention, in measures of stigma (i.e., enacted, internal, anticipated, courtesy, and perceived), HIV knowledge and attitudes towards young people who are HIV+ and –affected;
● Objective 2: To assess the intervention effect on HIV testing behavior among HIV-negative sexually-active young people;
● Objective 3: To assess the intervention effect on linkage to care, initiation of Antiretroviral Therapy (ART), and adherence to ART among HIV+ young people;
● Objective 4: To evaluate how, and under what circumstances, the intervention had an effect.

Canada 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Imelda Bates
ID:
Development of a complex quality improvement intervention for timely blood transfusions for the management of postpartum haemorrhage (PPH) in Uganda
REFNo: HS579ES

1. To map out active transfusing facilities and blood centres in two districts in Uganda and create a profile of baseline measures of quality of PPH management and blood transfusion services (e.g. availability of blood, safety of blood, timeliness of referrals of women with PPH, regular measurement of haemoglobin in PPH patients) for each district
2. To determine key barriers to the appropriate management of PPH, including blood transfusion
3. To gain stakeholder buy-in and contribution to a lead-on quality improvement intervention’s design from all levels, with a specific view to feasibility and sustainability
UK 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Alison Elliott
ID: UNCST-2023-R006524
“Establishing a Single-Sex Controlled Human Schistosoma mansoni Infection Model for Uganda: Safety and Dose Finding” (CHI-S-Ug1)
REFNo: HS697ES

Primary objective: To investigate (1) the safety and tolerability and (2) the infectivity of male Schistosoma mansoni (Sm) cercariae in healthy adult Ugandan volunteers with (a) minimal prior exposure to Sm, and (b) intense prior exposure to Sm.
Exploratory objectives: To investigate the kinetics of controlled infection with male Schistosoma mansoni cercariae in healthy adult Ugandan volunteers (a) with minimal prior exposure to Sm, and (b) with intense prior exposure to Sm. To investigate immunological, metabolic and microbiome changes after infection with Schistosoma mansoni male cercariae. To investigate volunteer and wider community understandings of CHI in the context of CHI-S.


UK 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
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