Provia Ainembabazi
ID:
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BREAST CANCER RISK PERCEPTION AND RISK REDUCTION BEHAVIOURS OF FIRST DEGREE FEMALE RELATIVES OF BREAST CANCER PATIENTS AT UGANDA CANCER INSTITUTE, KAMPALA, UGANDA
REFNo: HS277ES
General Objective
The general objective of this study is to explore self-perceived risk of breast cancer and intentions for screening and adoption of risk reduction behaviors among first degree female relatives of breast cancer patients attending Uganda Cancer Institute so as to inform design of interventions to enhance uptake of early detection and prevention services.
Specific Objectives
1. To explore self-perceived risk of breast cancer and intended risk reduction behaviors among first degree female relatives of breast cancer patients at UCI.
2. To determine factors associated with self-perceived risk of breast cancer among the first degree female relatives of breast cancer patients at the UCI.
3. To determine the factors associated with risk-reduction behaviors among the first degree female relatives of breast cancer patients at UCI
4. To describe perceived barriers for adoption of risk reduction behaviors among first degree female relatives of breast cancer patients at the UCI.
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Uganda |
2019-02-12 |
2022-02-12 |
Medical and Health Sciences |
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Non-degree Award |
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Stephen KIIRYA Kisembe
ID:
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Psychosocial predictors of sexual risk behaviour among HIV infected and affected adolescents in HIV affected homes of Uganda
REFNo: SS270ES
Despite the long-lasting psychosocial impacts of HIV and the rising number of children progressing to adolescence and reproductive stages with HIV infection and or exposure in Uganda, the extent and factors of psychosocial and sexual risks among adolescents in HIV-exposed homes is unknown. Existing studies have ignored this population yet they are many and prone to psychosocial risks of HIV and focused on either older HIV-infected adolescents attending HIV care or young orphans. Additionally, these studies mainly examined levels and demographic factors of psychological distresses and risky sexual practices and do not therefore offer ample knowledge about the psychosocial situation and sexual risk behaviour among varied adolescents in HIV-affected homes to facilitate inclusive programming. This knowledge deficit begets three research questions, namely 1) What is the psychosocial and sexual risk behaviour situation of HIV infected and affected adolescents living in HIV-affected homes of Uganda? 2) How do HIV infected and affected adolescents compare concerning the psychosocial and sexual risk behaviour situations? 3) Does the psychosocial situation predict sexual risk behaviour in these groups?
The proposed research therefore aims to: 1) determine the psychosocial and sexual risk behaviour situation of HIV infected and affected adolescents in HIV-affected homes across three HIV-burdened districts in Uganda; 2) compare the socio-demographic contexts and levels of community stressors, psychosocial distresses, coping ways and sexual risk behaviours of the two groups; 3) examine the coping mediated psychosocial predictors of sexual risk behaviour in these groups; and 4) evaluate if socio-demographic factors (age, sex, etc.) moderate the coping mediated associations between community stressors, psychosocial distresses and sexual risk behaviour in this population.
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Uganda |
2019-02-12 |
2022-02-12 |
Social Science and Humanities |
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Degree Award |
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Alfredo Guarino
ID:
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Acute gastroenteritis as a presenting symptom for malaria
REFNo: HS225ES
The aim of the study is to investigate the prevalence of Acute Diarrhea in Children with Malaria in Northern Uganda, a high-transmission malaria setting where there is paucity of data on the etiological agents of childhood diarrhea.
There is a solid scientific basis that could explain the pathogenesis of diarrhea in severe malaria.
The starting point for our working hypotheses is the positive feedback of Ugandan and Italian Doctors who have been working in Lacor Hospital’s Children Ward, whose practical and clinical experience seems to confirm an increased rate of GI symptoms in children with malaria.
There are previous clinical controlled Studies on the subject, however, despite the scientific premises and the clinical observations, these Studies have produced inconsistent and inconclusive results, and eventually failed to demonstrate a statistically significant prevalence of diarrhea in children with malaria. Moreover, setting, study groups and secondary endpoints differ from our Study.
In conclusion and to the best of our knowledge, our Study would be the first to show a statistically significant association between acute diarrhea and malaria. The Study would also be the first to be performed since the introduction of artemisinin-based therapies for the treatment of malaria. Investigating the time of response, and the factors affecting an early (< 24 h) or late resolution (>24h) of diarrhea could provide new extra information on the clinical outcomes of children with GI symptoms during severe malaria treated with IV artesunate and ACTs and provide new prognostic factors on admission.
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Italy |
2019-02-05 |
2022-02-05 |
Medical and Health Sciences |
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Non-degree Award |
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Irene Lubega
ID: UNCST-2019-R000658
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Immunogenicity of Fractional One-fifth and One-half Doses of Yellow Fever Vaccine Compared to Full Dose in Children 9-23 months old in Uganda
REFNo: HS244ES
Primary
• Assess whether seroconversion following one-fifth (0.1 ml) and one-half (0.25 ml) doses of YF 17DD vaccine is non-inferior to seroconversion following a full dose (0.5 ml) at 4 weeks post-vaccination in children aged 9 – 23 months
Secondary
• Assess whether the proportion of baseline seronegative children that are seropositive following one-fifth (0.1 ml) and one-half (0.25 ml) doses of YF 17DD vaccine is non-inferior to the proportion seropositive following a full dose (0.5 ml) of vaccine at 12 months post-vaccination
•
Compare the geometric mean antibody titers following the fractional doses to the geometric mean titer following the full dose at 4 weeks and 12 months post vaccination
• Describe the safety profile of fractional and full-dose YF 17DD vaccine in children 9-23 months
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Uganda |
2019-02-05 |
2022-02-05 |
Medical and Health Sciences |
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Non-degree Award |
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Nicholas Chapoy
ID:
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Title of research project: Dual articulation in the communication system of mountain gorillas?
REFNo: NS82ES
The emergence of combinatoriality (phonology and syntax) in human language represents one of the key evolutionary transitions in life (Maynard Smith & Szathmary 1995). Despite its significance, we know very little regarding how unique this capacity is to humans or the evolutionary progression of this trait. By searching for core features of language, such as its combinatoriality, in the communication systems of closely related species to humans, particularly the primates, it is possible to shed light on whether the components of language are de novo evolved traits in humans or whether they have their origins rooted in the primate lineage.
With this project, I aim to shed light on how unique combinatorics is to human language through empirically investigating the presence of linguistic forms of phonology and syntax in one of our closest living relatives, the gorilla.
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USA |
2019-02-05 |
2022-02-05 |
Natural Sciences |
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Non-degree Award |
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