Esther Uwimaana
ID:
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Heme oxygenase-1 and neopterin plasma levels and their role in distinguishing active from latent TB in HIV/TB co-infected patients
REFNo: HS301ES
1. To determine and compare the median plasma levels of HO-1 1(in pg/ml) and neopterin (in ng/ml) among HIV patients co-infected with active TB, latent TB infection and individuals without TB infection alone attending Rubaga hospital.
2. To determine the diagnostic performance (sensitivity, specificity, positive predictive values and negative predictive values) of HO-1 and neopterin in diagnosis of latent tuberculosis infection using QuantiFERON2-TB test for latent TB infection as the gold standard.
3. To determine the diagnostic performance (sensitivity, specificity, positive predictive values and negative predictive values) of HO-1 and neopterin in diagnosis of active tuberculosis using sputum culture as the gold standard.
4. To determine the correlation between neopterin and HO-1 plasma levels with QuantiFERON2-TB Gold test in diagnosing latent TB infection.
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Uganda |
2019-02-19 |
2022-02-19 |
Medical and Health Sciences |
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Degree Award |
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Kathryn LaRusso E
ID:
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Access to Essential Surgical Care and Bellwether Procedures for Children in Uganda: A Public-Sector Evaluation
REFNo: HS231ES
Primary objectives:
1. To conduct a nationwide survey using a convenience sample of two regional and two general referral hospitals in each region (Northern, Eastern, Western, and Central) of Uganda, and the national referral hospital (17 total facilities), using surgical capacity assessments to assess the availability of essential and emergency surgical care (EESC) for children.
i. To pilot the new WHO-PGSSC-GICS Children’s Surgical Assessment Tool (CSAT) and compare the results with PediPIPES to assess the validity, usability and reliability of the new CSAT tool.
2. To identify candidate bellwether procedures for children’s surgery that can be used as a benchmark for essential surgical care for children based on national, regional and general hospital logbook data, surgical capacity assessments, and perioperative mortality if available.
Secondary objectives:
3. To identify if the ratio of emergent surgery to elective surgery (Ee ratio) using logbook data from national, regional and general hospitals can be a simple and valid indicator of access to pediatric surgical care.
4. To verify if a convenience sample of 1-month of logbook data collection can reliability predict perioperative mortality rate vs 3- or 6-months of logbook data collection at MRRH.
|
USA |
2019-02-18 |
2022-02-18 |
Medical and Health Sciences |
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Non-degree Award |
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Sarah Baird
ID:
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INCORPORATING MENTAL HEALTH PROGRAMMING INTO ADOLESCENT EMPOWERMENT PROGRAMMING.
REFNo: HS318ES
Despite adolescent girls being at high risk of anxiety, depression, and other forms of psychological distress, there is little extant evidence on how to treat mood disorders among adolescents in developing countries in a cost-effective manner.
The aim of our research projects is to evaluate the use of group based interpersonal therapy (IPT-G) in reducing the prevalence of anxiety and depression among adolescents in developing countries.
The specific objectives of the research project are the following:
1. To estimate the causal effect of IPT-G on the psychological wellbeing of adolescent females who are identified as at risk of anxiety and depression at baseline
2. To estimate the marginal effects of adding income support following the intervention, on the sustainability of IPT-G results on anxiety and depression.
3. To investigate the relationship between improved psychological wellbeing among adolescents (as a result of the intervention) and school attainment, teenage pregnancy, child marriage and risky behavior.
4. To find if ELA clubs can serve as a pathway to reach and engage adolescent females who are most affected by mental health disorders.
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New Zealand |
2019-02-12 |
2022-02-12 |
Medical and Health Sciences |
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Non-degree Award |
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GODFREY OSINDE
ID:
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The association between ABCB1 gene C3435T polymorphism and Doxorubicin pharmacokinetics in Breast Cancer patients at Uganda Cancer Institute
REFNo: HS239ES
1. To determine the pharmacokinetics of doxorubicin in breast cancer patients in
Uganda. 2. To determine the frequencies of the ABCB1 gene: C3435T SNP in
breast cancer patients in Uganda. 3. To determine the association between the
ABCB1 gene: C3435T SNP and PK of doxorubicin in breast cancer patients.
|
Uganda |
2019-02-12 |
2022-02-12 |
Medical and Health Sciences |
|
Non-degree Award |
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EMMANUEL NAMBALE BUKUWA NAMBALE
ID:
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THE ROLE OF SAVINGS GROUPS ON SMALLHOLDER AGRO-INPUT USE IN SIRONKO DISTRICT, UGANDA
REFNo: A38ES
The main objective of this study is to investigate the impact of membership in a savings group on Agro-input use by smallholder farmers.
Specific objectives
1. To determine the proportion of group savings spent on agro-inputs by group members 2. To determine the difference in use of agro-inputs between members and non-members of savings groups
3. To identify factors determining the level of spending on agro-inputs
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Uganda |
2019-02-12 |
2022-02-12 |
Agricultural Sciences |
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Degree Award |
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