Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Wilber Sabiiti
ID: UNCST-2024-R016293
Field clinical evaluation of the NG-Test Point of Care lateral flow device (LFD) for monkeypox diagnosis in Uganda
REFNo: HS5602ES

To evaluate detection performance and clinical agreement of Rapid Point of Care (POC) antigen assay for diagnosis of mpox among clinically suspected patients in healthcare facilities in Kampala, Wakiso, Mukono, and Nakasongola districts in Uganda.

Specific objective 1
To determine the diagnostic sensitivity, specificity, & predictive values of the Rapid NG-Test antigen
assay in comparison to PCR and sequencing among patients with mpox
Specific objective 2
To identify MPXV clade (s) circulating among patients with mpox through virologic metagenomic
sequencing

Uganda 2025-03-14 17:48:15 2028-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOLLY KAKKAYI NYESIGIRE
ID: UNCST-2024-R004296
TALENT MANAGEMENT PRACTICES AND EMPLOYEE PERFORMANCE IN SELECTED PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS3682ES

The objectives of this study are:
1. To examine the influence of talent attractiveness on employees performance in Public Universities;
2. To investigate the effect of talent motivation on employees performance in Public Universities;
3. To explore the effect of talent development on the performance of employees in Public Universities;
4. To establish the relationship between talent retention and employees performance in Public Universities.
5. To examine the moderation effect of employee commitment on the relationship between talent management practices and employee performance.

Uganda 2025-03-14 17:45:15 2028-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
Victor Musiime
ID: UNCST-2021-R013794
A global phase 3, randomised, double-blind and placebo-controlled study evaluating the efficacy and safety of etavopivat in adolescents and adults with sickle cell disease
REFNo: HS5637ES

1. To demonstrate superiority of
treatment with etavopivat
versus placebo in adolescents
and adults with SCD.
2. To evaluate clinical efficacy
measures of etavopivat treatment
versus placebo in adolescents
and adults with SCD
3. To assess clinically meaningful
improvement in fatigue and
functional exercise capacity
and QOL measures of
adolescents and adults with
SCD taking etavopivat
treatment compared to placebo
Uganda 2025-03-14 17:26:26 2028-03-14 Medical and Health Sciences Clinical Trial Non-degree Award
UMI BUNU OMAR
ID: UNCST-2024-R002604
ASSESSMENT OF THE IMPACT OF SUBSTANCE OF ABUSE AMONG YOUTH IN BUSHENYI DISTRICT, WESTERN UGANDA.
REFNo: HS5415ES

i) Determining the prevalence and associated factors of substance of abuse among youth in Bushenyi District, Western Uganda.
ii) Assess the patterns of abused substances among the youth in Bushenyi District, Western Uganda.
iii) Determine the impact of substance of abuse on the youth in Bushenyi District, Western Uganda.
iv) Evaluate interventions implemented against abused substances among youth in Bushenyi District, Western Uganda

Kenya 2025-03-14 16:57:28 2028-03-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Francis Okello
ID: UNCST-2019-R000024
Understanding the economic impact of universal household hand hygiene in children under five in Uganda
REFNo: HS3181ES

To explore the health inequality impact of providing alcohol-based hand rub to mothers enrolled in the Babygel trial.,To determine the association between catastrophic health expenditure and under-five mortality in Uganda.,To estimate the extent to which handwashing with soap offers financial risk protection from out-of-pocket expenditure for treatment of diarrheal disease in children under five in Uganda. ,The main objective is to assess the benefits of household hand hygiene practices in terms of financial risk protection and reduction of health inequality. Furthermore, we will explore the association between under-five mortality and catastrophic health expenditure.,
Uganda 2025-03-14 16:38:36 2028-03-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Margaret Nagawa
ID: UNCST-2022-R009705
EARLY NUTRITIONAL INTERVENTION FOR NUTRITIONALLY AT-RISK INFANTS UNDER 6 MONTHS OF AGE TO REDUCE MALNUTRITION IN THE FIRST YEAR OF LIFE
REFNo: HS3503ES

5. To assess the maternal and health worker perceptions on the integrated intervention package.,4. To assess the effect of an early integrated family intervention program for LBW and undernourished children u6m on growth in the first year of life.,3. To understand the barriers and facilitators to the integration of maternal mental health care and community-based management of malnutrition in infants u6m of age.,2. To assess the prevalence of maternal mental health among caregivers of u6m infants.,1. To determine the factors associated with malnutrition among infants u6m of age and challenges caregivers of LBW and undernourished infants face. ,2. To assess the prevalence of malnutrition among infants u6m and their associations, To assess the effect of an early integrated nutrition intervention for nutritionally at-risk infants u6m of age in reducing malnutrition in the first year of life. ,
Uganda 2025-03-14 16:37:34 2028-03-14 Medical and Health Sciences Clinical Trial Degree Award
Joseph Mukasa
ID: UNCST-2024-R015786
Youth with Disabilities in Local Government Development Implementation: Exploring the Inclusivity of Mainstream Livelihoods Programmes in South-Western Uganda
REFNo: SS3674ES

The objectives of the research project are to:
1.Conduct a scoping review on the inclusion of youth with disabilities in mainstream livelihood programmes.
2.Determine the participation of youth with disabilities in the implementation of mainstream livelihood programmes.
3.Investigate the factors influencing the inclusion of youth with disabilities in mainstream livelihood programmes.
4.Explore the role played by Organisations of Persons with Disabilities in promoting the inclusion of youth with disabilities in mainstream livelihood programmes.
5.Propose a framework for practicing disability inclusive youth livelihoods development in local government.

Uganda 2025-03-10 18:06:19 2028-03-10 Social Science and Humanities Non-Clinical Trial Degree Award
OKELLO DAMOI JOSEPH
ID: UNCST-2022-R011560
EFFECT OF VIDEO-BASED PATIENT EDUCATION ON PATIENT ANESTHESIA, ENDOSCOPY LITERACY, AND SHOW-UP FOR THEIR INTENDED PROCEDURES AT KYABIRWA SURGICAL CENTER – JINJA CITY
REFNo: HS4465ES

To evaluate the effect of video-based education on surgical procedure attendance among patients at Kyabirwa Surgical Center ,To evaluate the effect of video-based education on the level of patient knowledge about endoscopy among patients at Kyabirwa Surgical Center,To evaluate the effect of video-based education on the level of patient knowledge about anesthesia among patients at Kyabirwa Surgical Center,To determine the level of patient knowledge about, and uptake of their scheduled procedure after reception of conventional and video-based patient education at Kyabirwa Surgical Center,The goal of this research is to evaluate the effect of video-based education on patient literacy about endoscopy and anesthesia, and surgical procedure attendance (show up) at Kyabirwa Surgical Center, Jinja.,
Uganda 2025-03-10 18:03:34 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dithan Kiragga
ID: UNCST-2024-R004458
Project Evaluation Protocol for the ACE-BUNYORO Project, Titled: “Accelerating and Sustaining HIV Epidemic Control and Related Diseases in Hoima (Bunyoro) Region in the Republic of Uganda under the President's Emergency Plan for AIDS Relief (PEPFAR)” _{ACE-Bunyoro}.
REFNo: HS5579ES

Evaluation objectives: The evaluation will assess;
a) The extent to which the project achieved its specific objectives as stated in the grant application. b) The relevance of ACE Bunyoro project in i) accelerating and sustaining HIV epidemic control
and strengthening regional, district, and community system capacities to achieve and sustain
HIV epidemic control, as perceived by government, district, health facility and project stakeholders, ii) addressing the health needs of its direct beneficiaries (clients) in Bunyoro region
c) The potential for sustainability of project components, results achieved and other efforts aimed at achieving HIV epidemic control in Bunyoro region.

Uganda 2025-03-10 18:01:54 2028-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Laura Munro Catherine
ID: UNCST-2025-R016668
Investigating the differences in bark feeding behaviour between two wild chimpanzee communities
REFNo: NS918ES

1. To provide new insights into the potential environmental and social drivers of self- medication behaviour in wild chimpanzees, and specifically examine whether community plays a role
2. To provide further evidence of self-medication behaviour in chimpanzees at BCFS
3. To produce more accurate forest compositional data of BCFS for future research and
conservation purposes
4. To add to the evidence of urinalysis as an effective non-invasive health monitoring
method for wild chimpanzees

UK 2025-03-10 17:57:11 2028-03-10 Natural Sciences Non-Clinical Trial Degree Award
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