Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Luiza CardosodeAndrade
ID: UNCST-2025-R018410
 Measuring chlorination in areas with active Evidence Action chlorine delivery interventions
REFNo: SS3948ES

This study aims to assess the take-up of drinking water chlorination under DSW and ILC in Uganda and to compare different measurement methodologies to help improve monitoring protocols. The primary outcome of interest is the total number of people who use water pointers with DSW or ILC for which we can detect chlorine residual in the drinking water. Secondary outcomes explore differences in the methods used to estimate chlorination. In particular, we are interested in comparing chlorination rates measured using two different sampling frames (self-reported water point users and water point users listed) and two different chlorine residual measurement instruments (color discs and colorimeters). The tertiary outcome is the functionality of chlorination devices, which may be connected to low adoption. Finally, additional data will be collected to perform an exploratory analysis on other factors that may influence the adoption of chlorine for water treatment, such as the distance to the nearest water point where chlorine is available and the occurrence of symptoms related to the consumption of contaminated water.
 Brazil 2025-07-04 14:02:44 2028-07-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
 Maternal Ultrasound Prospective Observational Study for Machine Leaning Model Training
REFNo: HS6020ES

1. Collect ultrasound data from pregnant and non-pregnant individuals presenting at Kawempe national referral hospital. 2. Use the collected data and ultrasound images to train and validate MOBUS algorithms.,
 Uganda 2025-07-04 14:00:42 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bernard Kikaire
ID: UNCST-2021-R011663
 SEROPREVALENCE OF MARBURG VIRUS INFECTION AND OTHER WHO-PRIORITY PATHOGEN IN THREE (3) COUNTRIES IN AFRICA
REFNo: HS6241ES

Primary objectives 1.To assess previous exposure to Marburg Virus (MARV) Infection in the general population in three (3) African countries, determined by measuring circulating IgG antibodies.
2.To estimate MARV force of infection (FOI) in the three (3) African countries. 3.To develop a platform for the implementation of seroprevalence of WHO priority pathogens in Africa Secondary objectives 1.
To characterize age-specific and gender-specific seroprevalence trends. 2.To determine risk factors associated with prior infection with MARV in the three (3) African countries. 3. To assess host genetic factors including single nucleotide polymorphism (SNP) of candidate genes that could be associated with susceptibility/protection from infection with MARV and other outbreak-worthy pathogens. 4.To estimate the seroprevalence of other WHO priority filovirus pathogens, including EBOV, SUDV, BDBV, TAFV, RAVN, etc. Exploratory objectives 1.To evaluate potential cross-reactivity of MARV IgG with other filoviruses. 2.To investigate neutralizing capacity of human monoclonal antibodies against MARV
Uganda 2025-07-04 13:58:59 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ERIC WOBUDEYA
ID: UNCST-2019-R001047
 Paediatric Post-TB home-based Pulmonary Rehabilitation Feasibility Study
REFNo: HS6222ES

Primary objective:
• To explore the feasibility of implementing a 6-week at home pulmonary rehabilitation program in children with diagnosed with PTLD, including measures of participant retention and adherence.

Secondary objectives:
• To evaluate the change in health-related quality of life following the pulmonary rehabilitation intervention.
• To assess the change in exercise capacity following the 6-week pulmonary rehabilitation intervention.
• To explore the experiences and perceptions of children, caregivers, and healthcare providers related to the acceptability and feasibility of the pulmonary rehabilitation program

 Uganda 2025-07-04 13:57:06 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tarekegn Abeku Abose
ID: UNCST-2023-R005864
 improving early warning and control of mosquito-borne disease outbreaks caused by extreme weather in Uganda
REFNo: HS5162ES

Main Objective
1. The project’s main objective is to strengthen the health system capacity in Uganda for improved early warning and rapid control of mosquito-borne disease outbreaks caused by extreme weather events, focussing on malaria RVF and YF.
Specific Objectives
1. 1. To document past mosquito-borne disease outbreaks in Uganda and analyse their association with extreme weather
2. 2. To develop and validate a risk index and early warning models to forecast the outbreaks
3. 3. To develop a platform that maps risks and generates predictions continuously, where real-time surveillance data feed into, for routine use by disease control programmes
4. 4. To develop an outbreak preparedness and response plan for various risk scenarios
5. 5. To facilitate adoption and use of the system
6. 6. To engage communities in the research activities
 UK 2025-07-04 13:55:42 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Francis Kiweewa
ID: UNCST-2020-R014929
 Longitudinal observation of cardiovascular diseases among people living with HIV in Lango Sub-region, Northern-Uganda.
REFNo: HS5900ES

Primary Objective
Assess the burden, risks and correlates of cardiovascular diseases (CVD) among people living with HIV (PLWH) in Northern Uganda to inform strategies for prevention, care and treatment in Sub-Saharan Africa.
The primary objective will be achieved through several secondary an explorative objective themed around forming a comprehensive understanding of the epidemiological, clinical, socio-behavioural, immunological, genetic, and microbiome-related factors influencing CVD among PLWH. The secondary and exploratory objectives are detailed in the attached protocol
 Uganda 2025-07-04 13:54:27 2028-07-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sam Ononge
ID: UNCST-2020-R000328
 A CLINICAL TRIAL TO EVALUATE THE PERFORMANCE AND SAFETY OFTHE WEKEBERE SYSTEM FOR MONITORING FETAL WELLBEING DURING LABOUR
REFNo: HS3407ES

The overall objective of this study is to demonstrate safety and performance of wekebere fetal monitoring system.

Specific Objectives
To determine accuracy of wekebere fetal monitoring in comparison with gold standard. To determine the safety of wekebere system
To determine’ uterine contractions

 Uganda 2025-06-30 9:35:11 2028-06-30 Medical and Health Sciences Clinical Trial Non-degree Award
Felix Bongomin
ID: UNCST-2020-R014224
 LIAISON® QuantiFERON®-TB Gold Plus II for the Diagnosis of Active and Latent Tuberculosis in Uganda
REFNo: HS6213ES

To evaluate the automated LIAISON® QuantiFERON® -TB Gold plus II immunoassay for the detection of IFN-γ in human lithium heparin plasma from subjects at low risk for M. tuberculosis infection, mixed risk for M. tuberculosis infection and with active TB disease.,
 Uganda 2025-06-30 9:16:34 2028-06-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Haruna Muwonge
ID: UNCST-2019-R000128
 Retrospective Analysis of RSV RTI Prevalence, Coinfections, and Risk Factors among Older Adults in Uganda: A Study Based on Sentinel Surveillance Data
REFNo: HS5423ES

Objectives
General Objective
To determine the prevalence, associated factors, and coinfection patterns of Respiratory Syncytial Virus (RSV) respiratory tract infections (RTI) among adults aged 60 and above in Uganda using sentinel surveillance data.
Specific Objectives
1. To determine the prevalence and seasonal trends of RSV RTI among older adults in Uganda using data collected from sentinel surveillance sites
2. To examine the relationship between comorbid conditions such as cardiovascular disease, diabetes, and chronic kidney disease, and the severity of RSV RTI among older adults in Uganda.
3. To determine the prevalence of coinfections with other respiratory viruses—SARS-CoV-2, Influenza A/B, and Pandemic A(H1N1) 2009—among older adults with RSV RTIs in Uganda.
4. To assess the association between coinfections with other respiratory viruses —SARS-CoV-2, Influenza A/B, and Pandemic A(H1N1) 2009— and clinical outcomes, including disease severity, hospitalization rates, and mortality, among older adults with RSV RTIs in Uganda.

 Uganda 2025-06-30 9:14:46 2028-06-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Elyanu James
ID: UNCST-2021-R013210
 OPTIMAH Study: OPTImizing Malaria And HIV treatment in a shifting landscape in Africa
REFNo: HS6165ES

PRIMARY OBJECTIVES
1. Assess the impact of HIV/DTG on weight gain (BMI) in Ugandan children ages 5 to 17 years of age over two years of follow-up.
2. Assess for PK drug-drug interactions between the two most widely used ACTs
(AL or AS-AQ) and DTG in longitudinal cohorts of HIV-uninfected children and CLHIV living in a high endemic malaria region (Busia).
3. To assess the 28- and 42-day efficacy of AL and AS-AQ for the treatment of uncomplicated malaria in children with and without HIV in a setting where artemisinin resistance has emerged.

SECONDARY OBJECTIVES
1. To assess the impacts of DTG on changes in body composition, waist circumference, and metabolic derangements over 2-years of longitudinal follow-up.
2. To assess the impact of repeated malaria infection on changes in weight gain in CLHIV on DTG (comparing HIV-infected cohorts in Busia and Kampala).
3. To determine if changes in DTG PK exposure in the presence of repeated courses of ACTs are associated with impacts on virologic control (pharmacodynamics).
4. To assess for the development of dolutegravir-associated resistance mutations over two years of follow-up.
5. To determine if changes in ACT exposure in the presence of daily DTG for HIV treatment are associated with impacts on malaria treatment outcomes.
6. To critically compare the PK exposure of artemether, artesunate, and DHA in the context of the two leading ACTs in Africa and assess for associations between the PK exposure of artemisinin derivatives as drivers of parasitologic outcomes such as parasite clearance rates for artemisinin-sensitive and resistant infections.
7. To assess levels of gametocytemia in children with and without HIV infection and with artemisinin-sensitive and -resistant infections
8. To determine if repeated course of AL and AS-AQ are associated with selection of resistance-associated mutations to the partner drugs and/or the artemisinin component.
9. To identify novel mutations in known and/or putative loci associated with resistance to artemisinins, lumefantrine, and amodiaquine using amplicon-based sequencing and/or other genotyping methods.
10. To assess the exposure of unbound DTG, lumefantrine, and DEAQ and association with clinical outcomes (viral load or parasitemia)



 Uganda 2025-06-26 23:59:42 2028-06-26 Medical and Health Sciences Clinical Trial Non-degree Award
Daniel Magumba
ID: UNCST-2025-R018334
 PEDESTRIAN ROAD SAFETY IN KAMPALA: A MIXED METHODS STUDY OF THE WALKABILITY OF KAMPALA’S ROAD INFRASTRUCTURE
REFNo: HS6064ES

1.To assess the Walkability of Kampala City’s Road infrastructure.
2.To explore stakeholder perceptions on pedestrian safety and walkability of Kampala city.

 Uganda 2025-06-26 23:54:31 2028-06-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Charlot Diepvens
ID: UNCST-2025-R017733
 Demand-side enablers and barriers to epidemic preparedness: a mixed-method approach to understand priorities, acceptance and effective strategies for Ebola vaccines
REFNo: HS6132ES

The objective of this study is to examine demand-side factors that influence (enable or hinder) epidemic preparedness, with a focus on licensed Ebola vaccines. Specifically, it aims to visually identify and map key influencing factors, and to adequately translate their effects into quantitative models. This translation is critical, as decision-makers frequently rely on models—such as disease transmission models—to guide outbreak response strategies. Modeling has the potential to demonstrate the impact of specific interventions (e.g., additional training, improved guidelines, or the provision of dedicated funding) on vaccine use. This case study explores priorities and acceptance regarding licensed Ebola vaccines among decision makers. It also examines how these perceptions shift under different vaccination strategies, including reactive vaccination (during an outbreak) versus preventive vaccination (outside of an outbreak). More specifically, the studies objectives are to: 1. Identify and map key influences or determinants of vaccine use in Uganda through a conceptual systems diagram (e.g., perceptions of personal risk, fear of vaccine side effects), building on key informant interviews and group model building workshops. 2. Develop and validate a quantitative simulation model evaluating the impact of various vaccination strategies and interventions on vaccine use over time. 3. Derive insights from the diagram and model to inform policy and strategic decision-making at local and national levels regarding Ebola vaccine implementation. In short, the study will develop a visual representation of the problem space that can guide both policy and practice.
 Belgium 2025-06-26 23:52:36 2028-06-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
 Socio-Cultural and Anthropological Perspectives on Child Feeding and Care, Food Consumption Habits, Dietary Patterns and Purchasing Behaviours in Uganda
REFNo: HS5843ES

Examine similarities and differences in caregiving practices that affect children’s nutrition across high-producing agricultural areas, pastoral regions, and urban landscapes,Explore the current perception of social behaviour change communication on complementary feeding.,Assess household dietary and food consumption behaviour,Examine caregivers\' purchasing habits and children’s food preferences, considering economic and cultural factors.,To gather comprehensive anthropological data on the dietary habits of children under 2 and the purchasing behaviours of caregivers in the districts of Kamwenge, Napak, and the urban areas of Kampala,
 Uganda 2025-06-26 23:51:22 2028-06-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SEDRIC NABAASA NKUBA
ID: UNCST-2024-R016326
 Peer Influence, Alcohol Use and Risky Sexual Behaviors among Adolescent Students in Secondary Schools in Greater Mbarara
REFNo: SS3934ES

1. To explore the gender difference in prevalence of risky sexual behaviors among adolescent students in secondary schools in greater Mbarara.
2. To establish impacts of peer influence on risky sexual behaviors among adolescent students in secondary schools in greater Mbarara.
3. To determine the mediation effects of alcohol us on the relationship between peer influence and risk sexual behaviors among adolescent students in secondary schools in greater Mbarara.
4. To explore the perceptions of adolescent students in controlling risk sexual behaviors in secondary schools in greater Mbarara

 Uganda 2025-06-25 13:34:21 2028-06-25 Social Science and Humanities Non-Clinical Trial Degree Award
Victor Musiime
ID: UNCST-2021-R013794
 Understanding Post-Discharge Mortality in children living with HIV who are hospitalized (SUPPORT1-PDM)
REFNo: HS6005ES

1. To assess the impact of an improved follow-up on reducing PDM in CLHIV 2. To evaluate the performance of disease severity biomarkers in this specific population to predict PDM 3. To analyze changes in serial measurements of CMV and potential association with PDM at day +360 in CLHIV 4. To describe the number of children with persistent detection of a specific respiratory pathogen 5. To describe the number of children with persistent detection of specific gastrointestinal (GI) pathogens 6. To describe the number of cases of histoplasmosis in CLHIV, its clinical characteristics, and outcomes in the identified cases, up to +360 days after discharge 7. To describe the prevalence of MDR colonization at enrollment, the microorganism isolated, and the duration of the colonization 8. To describe the main characteristics of readmissions, deaths and morbidity during 1-year follow-up after enrollment
 Uganda 2025-06-25 13:30:24 2028-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JULIAN APAKO
ID: UNCST-2024-R004399
 LUNAS as a versatile and simple technique for malaria testing in a high transmission, rural setting
REFNo: HS5918ES

Primary objective - To determine the diagnostic accuracy of LUNAS POCT for malaria compared to common routine malaria testing (RDT and microscopy) during standard patient care in malaria-suspected individuals presenting at Kumi Hospital, Kumi, Uganda. Secondary objectives - To determine the diagnostic accuracy of LUNAS POCT for malaria compared to a commercial LAMP test - To determine the prevalence of malaria infections categorized by Plasmodium species. - To determine the correlation between time to positivity of both LAMP and LUNAS and parasitaemia as assessed by reference microscopy. - To determine the prevalence of P. falciparum harbouring deletions or mutations of the pfhrp2/3 gene in study participants, who have a P. falciparum infection with a parasitaemia as assessed by reference microscopy but a negative Pf HRP2/3 RDT result. - To determine the prevalence of Pf kelch13 (K13) gene mutations, which have been associated with resistance to artemisinin. - To determine the effectiveness of dried blood spots (DBS) for long term storage and transport of patient samples at ambient temperature for PCR testing.
Uganda 2025-06-25 13:26:35 2028-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catherine Atuhaire
ID: UNCST-2021-R013090
 MATERNAL INFANT BONDING AND BREAST-FEEDING OUTCOMES IN UGANDAN MOTHERS DIAGNOSED WITH POSTPARTUM DEPRESSION IN PUBLIC HEALTH FACILITIES IN MBARARA DISTRICT, SOUTH WESTERN UGANDA
REFNo: HS5848ES

1. To determine the prevalence of maternal bonding impairment among mothers diagnosed with PPD in a public health facility in Mbarara district, South western Uganda.
2. To determine the breast-feeding outcomes of children born to mothers diagnosed with PPD in a public health facility in Mbarara district, South western Uganda.
3. To explore the lived bonding and breast-feeding experiences of mothers Diagnosed with PPD in a public health facility in Mbarara district, South western Uganda

 Uganda 2025-06-25 13:21:19 2028-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve Wabule
ID: UNCST-2024-R004285
 DRIVERS OF NO-SHOWS FOR AMBULATORY APPENDECTOMY AMONG PATIENTS SCHEDULED FOR AMBULATORY APPENDECTOMY AT KYABIRWA SURGICAL CENTER
REFNo: HS6046ES

To establish the institutional drivers of no-shows for ambulatory appendectomy among patients scheduled for ambulatory appendectomy at Kyabirwa surgical center,To determine the patient-related drivers of no-shows for ambulatory appendectomy among patients scheduled for ambulatory appendectomy at Kyabirwa surgical center,To determine the prevalence of no-shows for ambulatory appendectomy among patients seeking ambulatory surgery at Kyabirwa surgical center,To assess the drivers of no-shows for ambulatory appendectomy among patients scheduled for ambulatory appendectomy at Kyabirwa surgical center,
 Uganda 2025-06-25 13:19:11 2028-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Atek kagirita
ID: UNCST-2024-R015689
 LABORATORY SYSTEM RESILIENCE TO CORONAVIRUS DISEASE-19 OUTBREAK; ITS PREDICTORS, POLICY, AND PRIVATE SECTOR SUPPORT IN UGANDA
REFNo: HS6101ES

General objective
To assess the level of laboratory system resilience to COVID-19 disease outbreak, its predictors, appropriateness of policies to support it, and capacity of private sector laboratories to impact it in Uganda
4.2.2 Specific objectives
1. To determine the level and characteristics of resilience among licensed / accredited COVID-19 testing laboratories in Uganda.
2. To establish the predictors of resilience among licensed / accredited COVID-19 testing laboratories in Uganda.
3. To describe private sector laboratory capacity to contribute to national laboratory system resilience during the COVID-19 pandemic outbreaks
4. To appraise the appropriateness of current/emerging policies to support laboratory resilience during the COVID-19 pandemic outbreaks
 Uganda 2025-06-23 13:30:18 2028-06-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Abel  Kakuru
ID: UNCST-2022-R009193
 Development of context-appropriate approaches for the recruitment and retention of women of childbearing age and pregnant women in antimalarial clinical trials
REFNo: HS6036ES

1. To understand the context, socio-cultural practices and beliefs around early pregnancy as well as collecting experience with and/or perception of previous clinical trials to inform the development of culturally acceptable and understandable communication materials about the SAFIRE trial, including the information sheets for obtaining consent.
2. To identify factors and individuals that may influence WOCBA and pregnant women’s decision-making around participation and retention in the clinical trial to be addressed as part of project procedures and communications.
3. To explore approaches for facilitating the inclusion of WOCBA and pregnant women (in early pregnancy) in the clinical trial, based on the findings from objective 2.
4. To identify key stakeholders (including household decision-makers, community leaders and opinion shapers, health sector actors), from community to national levels, to be included and involved in the community engagement strategy prior to trial implementation.

 Uganda 2025-06-20 9:25:32 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rita Nakalega
ID: UNCST-2019-R000599
 Exploring Neuro-Vascular Biomarkers in Young Adults with lifelong HIV and without HIV in Uganda: Insights from Carotid Ultrasound
REFNo: HS6038ES

Exploratory objectives/aims: To determine the prevalence of and relationships between HIV infection, carotid pathology, neurological and neurocognitive function, and serum markers of cardiovascular health and inflammation in a population of young adults living with HIV in Uganda who acquired the infection perinatally as well as uninfected age-matched controls,Secondary objective (Aim 2): To determine the prevalence of cognitive dysfunction, as determined by a battery of cognitive evaluations, of a population of young adults living with HIV in Uganda who acquired the infection perinatally, relative to uninfected age-matched controls.,Primary objective (Aim 1): To determine the prevalence of carotid pathology, as determined by ultrasound-based measurement of intima-media thickness (IMT), in a population of young adults living with HIV in Uganda who acquired the infection perinatally, relative to uninfected age-matched controls.,
 Uganda 2025-06-20 9:22:24 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kiel McGowan
ID: UNCST-2025-R017284
 Prevalence and patterns of coinfection with malaria and soil transmitted helminths among school-aged children in rural Northern Uganda: A cross-sectional study
REFNo: HS6039ES

To measure the prevalence of coinfection with malaria and STH among school-aged children and to identify factors that may be associated with infection.
 USA 2025-06-20 9:16:14 2028-06-20 Medical and Health Sciences Non-Clinical Trial Degree Award
MARY AGUNLOYE OLAOLUWA
ID: UNCST-2024-R003434
 EVALUATION OF THE ACTIVITIES OF LEAF EXTRACTS OF AVOCADO (Persea americana Mill.) IN HIGH-FAT DIET/ LOW- DOSE STREPTOZOTOCIN - INDUCED TYPE 2 DIABETES MELLITUS IN WISTAR RATS
REFNo: HS5401ES

1. To screen aqueous, ethyl acetate, and ethanol leave extracts of p. americana Mill for anti-hyperglycemic activity
2. To assess the anti-diabetic potential of selected extract in high-fat diet/low-dose streptozotocin-induced T2DM in Wistar rats in a dose dependent pattern, and identify it mechanism of action
3. To perform phytochemical screening and metabolite profiling of the selected bioactive extracts through integrated FT-IR, LC-MS and GC-MS
4. To assess the in silico interactions of compounds of avocado leaf with selected drug targets in type II diabetes.
5. To evaluate the biological activities of the in silico hit compounds using in vitro and in vivo analyses

Nigeria 2025-06-20 9:03:03 2028-06-20 Medical and Health Sciences Non-Clinical Trial Degree Award
GEOFFREYEDWIN SEMAMBO
ID: UNCST-2024-R015519
 prevalence and factors associated with Adverse maternal outcomes among emergency obstetric referrals delivered at Mbarara regional referral Hospital
REFNo: HS5740ES

To determine the factors associated with adverse maternal outcomes among emergency obstetric referrals at Mbarara Regional Referral Hospital,To describe the adverse maternal outcomes among emergency obstetric referrals delivered at Mbarara Regional Referral Hospital,To determine the prevalence of adverse maternal outcomes among emergency obstetric referrals delivered at Mbarara Regional Referral Hospital, To determine the prevalence and factors associated with adverse maternal outcomes among emergency obstetric referrals delivered at Mbarara Regional Referral Hospital,
 Uganda 2025-06-20 8:55:52 2028-06-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Gloria Lubega
ID: UNCST-2025-R017180
 Understanding HIV vertical transmission in Uganda in a population of urban mothers in the era of Dolutegravir based antiretroviral therapy(VERT)
REFNo: HS6095ES

Quantitative Objectives I. To identify level of utilisation of PMTCT and EID services among mothers living with HIV. II. To assess the factors associated with utilization of PMTCT services and EID services among mothers living with HIV. III. To identify factors associated with HIV vertical transmission in the era of Dolutegravir based therapy among mothers living with HIV. IV. To determine the proportion of pregnant women diagnosed with HIV that were linked to care and the time taken from HIV diagnosis to linkage to care among mothers living with HIV. Qualitative Objectives 1. To explore the experiences of women in the PMTCT program, including. • Barriers and facilitators for utilizing the program. • Adherence to instructions such as breastfeeding practices. • And the role of close relationships (partner, family and community members) in supporting women’s participation in PMTCT. 2. To obtain suggestions that can potentially improve the implementation of the PMTCT program
Uganda 2025-06-20 8:53:57 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Annah Tugaineyo
ID: UNCST-2024-R016504
 WORKPLACE EQUITY, PARTICIPATION IN STAFF COMMITTEES, STAFF WELFARE AND JOB SATISFACTION OF ACADEMIC STAFF IN PUBLIC AND PRIVATE UNIVERSITIES IN WESTERN UGANDA
REFNo: SS3835ES

-To examine the differences in workplace equity between academic staff in public and private universities in Western Uganda.

-To assess the underlying factors that stimulate job satisfaction among academic staff in public and private universities in western Uganda

-To analyze the differences in participation in staff committees between academic staff in public and private universities in Western Uganda.

-To determine the influence of workplace equity on job satisfaction among academic staff in public and private universities in western Uganda.

-To assess the mediating role of participation in staff committees in the relationship between workplace equity and job satisfaction in public and private universities in western Uganda.

-To investigate the mediating role of staff welfare in the relationship between workplace equity and job satisfaction in public and private universities in western Uganda.

 Uganda 2025-06-20 8:47:35 2028-06-20 Social Science and Humanities Non-Clinical Trial Degree Award
Anne Mette Kjaer
ID: UNCST-2024-R015303
 The Political Economy of Local Food System Governance: Impacts on climate -Vulnerable communities in Lake Victoria Border Region
REFNo: SS3899ES

1. Understanding and mapping national food governance ie policy initiatives, decisions and processes affecting food and livelihood security of climate-vulnerable communities in lake Victoria border region (WP1)
2. Understanding the implementation processes of these food system policies and decision with a focus on the effect of local government autonomy and capacity to address the food and livelihood of climate-vulnerable communities, and the nature of state-community encouters in these processes (WP2)
3. Understanding the lived experiences of food and livelihood security among the climate-vulnerable communities in Lake Victoria region, the perceptions they have of local and national food system policies, and the role these communities play in food system governance
 Denmark 2025-06-20 8:43:55 2028-06-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jolly  Kamugisha G.K.
ID: UNCST-2023-R005715
 Performance and Factors Affecting the Implementation of the Integrated Management of Acute Malnutrition Programme: A Study of Kampala, Mukono, Wakiso and Kayunga Districts
REFNo: HS6084ES

5. To document the lessons learnt and best practices during implementation of the IMAM program in the four target districts during the calendar year 2022 and 2023.,4. To establish factors that affect the utilization of IMAM services in the four target districts.,3. To determine factors influencing treatment outcomes of children with wasting in the four target districts.,2. To determine the performances of the integrated management of acute malnutrition program in the four target districts during the calendar year 2022 and 2023.,1. To identify the communities contributing to a high burden of childhood wasting caseload in health facilities in four target districts (Kampala, Mukono, Wakiso and Kayunga),The overall objective of this study is to assess the nutrition service delivery and factors influencing utilization of the IMAM programme in Kampala, Mukono, Wakiso and Kayunga districts,
 Uganda 2025-06-20 8:41:29 2028-06-20 Medical and Health Sciences Clinical Trial Non-degree Award
Evan Borkum
ID: UNCST-2025-R016987
 Evaluation of cash and cash plus intervention in Nakivale refugee settlement, Uganda
REFNo: SS3849ES

The non-profit organization GiveDirectly plans to implement a cash-plus program in Nakivale refugee settlement, which will supplement a large unconditional cash transfer with demand-driven skills training and apprenticeship; business coaching, mentoring, and entrepreneurship support; and access to financial services and financial literacy training. The objective of the study is to rigorously assess the impact of the program on household wellbeing through a randomized controlled trial.
Italy 2025-06-20 8:36:56 2028-06-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
 EVALUATION OF A PILOT PROJECT TO EXPAND ACCESS TO THE IMPLANT FAMILY PLANNING METHOD THROUGH COMMUNITY HEALTH EXTENSION WORKERS IN SELECTED DISTRICTS IN UGANDA
REFNo: HS5966ES

3. To determine competence of the CHEWs regarding insertion and removal of implants following training.,2. To assess the acceptability of the community-based implant by CHEWs among the stakeholders (health workers at the facility, FP clients in the community) ,1. To explore the perceptions of the stakeholders towards the implant provision task shifting to the CHEWs (stakeholders including the CHEWs, clients, health workers/ professionals and policy makers) ,The overall objective is to evaluate the implementation of a community-based implant intervention through training CHEWs on how to insert and remove implants, in order to understand the perceptions and acceptability of stakeholders towards task shifting the implants service provision to CHEWS, and determine the CHEWs attainment of competencies to insert and removal implants in the selected districts in Uganda,
 Uganda 2025-06-20 8:34:40 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Julian Benedict Kuttig
ID: UNCST-2025-R018435
 Youth Participation, Representation, and Civic Engagement in the Context of Social Cohesion: The Case of Uganda Martyrs University Nkozi and Rajshahi University, Bangladesh.
REFNo: SS3956ES

1. To investigate how student civic engagement contributes to social cohesion within university and local communities. 2. To understand the factors that shape student civic agency, including cultural, institutional, and policy influences. 3. To explore how lessons learned from diverse contexts can challenge the global North/South dichotomy and provide transferable insights into fostering social cohesion. 4. To shed light on the unique spatial and social dynamics of secondary cities as sites of youth civic engagement, offering a counterbalance to strictly urban- or rural-centric research.
Germany 2025-06-20 8:26:29 2028-06-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Cornelius Sendagire
ID: UNCST-2021-R004351
 Practice of Fluid Therapy in Critically Ill Invasively Ventilated Patients (PRoFLUID)––an International Multicenter Observational Cohort Study The PRoFLUID–investigators
REFNo: HS6063ES

3.1. General Objective To explore global practices in intravenous fluid and vasopressor therapy in invasively ventilated ICU patients. 3.2 Specific Objectives Describe the types and volumes of fluids administered in the first 3 and 7 days after initiation of invasive ventilation. Detail the timing, type, and duration of vasopressor and diuretic therapy. Assess daily urine output and cumulative fluid balances. Evaluate clinical outcomes (ventilation duration, ICU/hospital length of stay, and mortality). Compare practices across different geo-economic regions.
 Uganda 2025-06-20 8:20:52 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ellen Asiimwe
ID: UNCST-2024-R002415
 Academic demands and Mental Wellbeing of Upper Primary Learners in Uganda. A study of Government and Private Schools in Mukono Municipality.
REFNo: SS3902ES

To explore the learners’ experiences of extracurricular activities in Mukono municipality primary schools,To compare the effect of academic demands and mental wellbeing on upper class learners from government schools and private schools,To assess how the length of time (early start and late end) influences learners’ mental wellbeing,To establish how high expectations affect learners’ mental wellbeing, To assess the relationship between academic demands and mental wellbeing from of upper class learners in Mukono Municipality Schools.,
 Uganda 2025-06-20 7:56:25 2028-06-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rachel  Kabunga Rehema
ID: UNCST-2021-R005043
 Investigating the Feasibility of Implementing an Automated Diabetic Retinopathy Screening Algorithm in Southwestern Uganda
REFNo: HS5979ES

To describe the existing AI-based DR screening algorithms and their infrastructure
requirements based on published scholarly evidence globally.
2. To assess the existing capacity within the health facilities to support the implementation of an
AI-based DR screening system in Southwestern Uganda,
3. To assess the performance of the most context-appropriate existing AI-based DR screening
algorithms in Southwestern Uganda.
 Uganda 2025-06-20 7:50:07 2028-06-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Elizabeth Nyboer Ann
ID: UNCST-2023-R005929
 Social license and access in aquaculture: documenting perceptions of nutritional, economic, and environmental risks and benefits in Lake Victoria's fisheries
REFNo: SS3903ES

(1) document stakeholder views on the environmental, economic, and nutritional risks and benefits, (2) quantify stakeholder proximity to environmental risks, and (3) examine how different farm types affect risks, benefits, and access to those benefits for various stakeholders
 Canada 2025-06-20 7:47:42 2028-06-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Suubi4PrEP: Improving PrEP Access and Adherence Among Adolescent Girls and Young Women in Uganda
REFNo: SS3990ES

Suubi4PrEP will examine the effect of a multilevel intervention, combining HIV risk reduction that incorporates sessions on PrEP, peer supporters with lived experiences to facilitate linkage to and continued care, and economic empowerment components targeting financial barriers associated with PrEP access, PrEP initiation, uptake and adherence among AGYW in Uganda. Study aims are:

Aim 1: Examine the impact of Suubi4PrEP on PrEP initiation (primary outcome); and PrEP adherence (secondary outcome).

Aim 2: Examine the effect of Suubi4PrEP on hypothesized mechanisms of change (financial stability, PrEP stigma, self-efficacy, depressive symptoms, and social support) and intervention mediation.

Aim 3: Use mixed methods to explore multi-level factors that influence PrEP initiation and adherence.

Aim 4: Assess the cost and cost-effectiveness of the interventions.

Uganda 2025-06-20 7:41:25 2028-06-20 Social Science and Humanities Clinical Trial Non-degree Award
Dorothy Akongo
ID: UNCST-2023-R007564
 Pediatric Epilepsy in Busoga Region, Uganda – current management and factors associated with drug adherence and seizure control
REFNo: HS6004ES

The overall aim is to assess the current ability to diagnose and manage childhood epilepsy in
health facilities at different levels in Busoga region, Uganda and to describe pediatric epilepsy
patients followed at a Ugandan regional referral hospital to identify factors associated with
seizure control and epilepsy drug adherence.
 Uganda 2025-06-20 7:37:23 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jesca Audo Harriet
ID: UNCST-2019-R000209
 STUDENT LEARNING ACTIVITIES IN BIOLOGY LESSONS AS MEDIATORS OF SELF-EFFICACY AND GENERIC SKILLS IN UGANDA’S NEW LOWER SECONDARY CURRICULUM
REFNo: SS3915ES

The following objectives will serve as the study's direction. 1.To determine the level of student learning activities designed for students during Biology lessons in the lower secondary schools. 2.To determine the level of acquisition of generic skills among students during Biology lessons in the lower secondary schools. 3.To investigate the relationship between self-efficacy and student learning activities during Biology lessons in the lower secondary schools. 4.To examine the relationship between self-efficacy and generic skills acquisition among students during Biology lessons in the lower secondary school. 5.To examine the relationship between student learning activities and generic skills acquisition among students during Biology lessons in in the lower secondary schools. To investigate the mediating effect of student learning activities in relation to self-efficacy and generic skills acquisition among students during Biology lessons in the lower secondary schools.
 Uganda 2025-06-20 7:34:34 2028-06-20 Social Science and Humanities Non-Clinical Trial Degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 VAC52150EBL4006 entitled: “Prospective, Multi-country, Non-interventional, Case-control Study with Test-negative Controls to Estimate the Effectiveness of the Ad26.ZEBOV, MVA-BN-Filo Vaccine Regimen Against Ebola Virus Disease (EVD) in Real-world Setting
REFNo: HS6053ES

The primary objective of this trial is to estimate the vaccine effectiveness of the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen or a booster dose of Ad26.ZEBOV against polymerase chain reaction (PCR)-confirmed EVD in adults and children
 Uganda 2025-06-20 19:06:06 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Justus Turamyomwe
ID: UNCST-2025-R019115
 A Morphosyntactic Analysis of Runyankore-Rukiga Associative Nominals
REFNo: SS3955ES

1. To examine how associative nominals are marked in Runyankore-Rukiga
2. To Explicate how Runyankore-Rukiga nominals are derived.
3.To establish the specific functions of associative modifiers in Runyankore-Rukiga associative constructions.
 Uganda 2025-06-20 19:00:22 2028-06-20 Social Science and Humanities Non-Clinical Trial Degree Award
Winnie Nakatudde
ID: UNCST-2025-R018763
 Understanding Refugee Voices: Refugee Girls Experiences with Uganda’s Education Policies.
REFNo: SS3950ES

• To understand the extent to which Uganda’s current education policies and initiatives effectively meet refugee girls’ heterogeneous aspirations and needs.
• To find out how refugee girls in Nakivale settlement navigate educational trajectories, considering their gender, ethnicity, and social backgrounds.
• To examine the extent to which refugee girls in Nakivale settlement draw on and pursue ecological support systems (family, community, NGOs) to aid their educational integration.
• To determine how the lived experiences of refugee girls in Nakivale settlement differ from those of refugees in an urban setting.
 Uganda 2025-06-20 18:50:23 2028-06-20 Social Science and Humanities Non-Clinical Trial Degree Award
Denis Kimbugwe
ID: UNCST-2025-R017664
 Systemic inflammation in pregnant and postpartum mothers with HIV and their children: relationship with early child growth (SIPPH Study).
REFNo: HS6041ES

1. Evaluate the association of second trimester maternal inflammatory markers with CHEU growth patterns from birth through 2 years.
2. Evaluate the association of maternal inflammatory markers during first 2 months postpartum with CHEU growth patterns from birth through 2 years.
3. Evaluate the association of CHEU inflammatory markers at birth with growth patterns from birth through 2 years.
 Uganda 2025-06-20 18:38:43 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Kajjimu
ID: UNCST-2021-R013696
 Emergency Care Research in Uganda: Priorities, Barriers, and Strategies
REFNo: HS5847ES

To identify research priorities, evaluate existing barriers, and propose interventional strategies for enhancing emergency care research in Uganda. ,
 Uganda 2025-06-20 18:32:38 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Maxson Anyolitho Kenneth
ID: UNCST-2021-R013447
 Enhancing Integration of Adolescent Family Planning and Post-Abortion Care in Northern Uganda: A Citizen Science, Gender-Transformative Approach (CAFFP-PAC)
REFNo: HS6030ES

5. To document and disseminate best practices and lessons learned from implementing the integrated CAFFP-PAC using a citizen science gender-transformative approach in Lira, Northern Uganda.,4. To evaluate the effectiveness of an integrated CAFFP-PAC using a citizen science gender-transformative program to improve access to, and utilization of family planning and post-abortion care services in Lira, Northern Uganda.,3. To co-design and implement an integrated CAFFP-PAC using a citizen science gender-transformative approach to improve access to, and utilization of SRH services in Lira, Northern Uganda.,2. To engage citizen scientists in identifying barriers to and facilitators for accessing and utilizing family planning and post-abortion care services in Lira, Northern Uganda.,1. To assess the baseline knowledge, attitude, and practices of adolescents regarding family planning and post-abortion care in Lira, Northern Uganda.,To improve access to, and utilization of SRH services by female and male adolescents and other underserved population groups in Lira, Northern Uganda through an integrated CAFFP-PAC using a citizen science gender transformative approach (CS-GTA).,
 Uganda 2025-06-18 20:27:59 2028-06-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Samantha Agasha
ID: UNCST-2025-R017839
 Exploring Sexual and Gender-Based Violence Against Women in Sports in Uganda: Causes, Impacts, and Interventions
REFNo: SS3892ES

Primary Objective: To explore the prevalence, causes, impacts, and interventions related to sexual and gender-based violence against women in sports in Uganda. Specific Objectives: • To assess the prevalence and forms of SGBV in Ugandan sports. • To examine the underlying causes and contributing factors of SGBV within sports institutions. • To investigate the psychological, physical, and socio-economic impacts of SGBV on women athletes. • To evaluate the effectiveness of existing interventions and support mechanisms aimed at addressing SGBV in sports.
Uganda 2025-06-17 15:52:19 2028-06-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
Esther Kataate Namakula
ID: UNCST-2025-R016688
 A Study of Pedagogical Content Knowledge in Action: Exploring Gender Inclusive Practices in Physics Education in the context of Uganda
REFNo: SS3925ES

The study seeks to understand how Physics teacher educators in Uganda draw from their Pedagogical Content Knowledge (PCK) to incorporate gender-inclusive practices in their teaching, shaping the development of preservice teachers. The ultimate goal is to understand how PCK and gender-inclusive practices of Physics Teacher educators can support preservice teachers in fostering more inclusive and equitable Physics classrooms, thereby encouraging more girls to pursue the subject.
 Uganda 2025-06-12 9:27:13 2028-06-12 Social Science and Humanities Non-Clinical Trial Degree Award
Bienvenu Akowedaho Dagoudo
ID: UNCST-2025-R018501
 Women’s entrepreneurship and Participatory Guarantee System for agroecology and sustainable food system in Uganda
REFNo: A597ES

The objective of the research aims to evaluate women’s entrepreneurship and participatory guarantee system for agroecology foods systems in Uganda

In order to achieve the main research objective, four specific objectives have been elaborated.
• To analyze the relationship between organic farming and agroecology in Uganda;
• To evaluate organic farming efficiency in relation to agroecological approaches in Uganda;
• To assess women entrepreneurship eco-efficient organic farming in relation to agroecology and sustainable food systems in Uganda;
• To analyze participatory guarantee systems for organic certification in the agroecological perspective in Uganda.
 Benin 2025-06-12 9:22:00 2028-06-12 Agricultural Sciences Non-Clinical Trial Degree Award
Brenda Simbwa Nakafeero
ID:
Study title: HPV vaccination uptake, drop-out rate and associated factors among female adolescents in Wakiso district, Uganda
REFNo: HS5168ES

To determine uptake of HPV vaccination among female adolescents in Wakiso district, Uganda.
To determine drop-out rate of HPV vaccination among female adolescents in Wakiso district, Uganda.
To determine the factors associated to HPV vaccination uptake among female adolescents in Wakiso district, Uganda.
To determine the factors associated to drop-out rate of HPV vaccination among female adolescents in Wakiso district, Uganda.
To assess the knowledge and attitudes of female adolescents, parents, and healthcare providers towards the HPV vaccine in Wakiso, Uganda.

 Uganda 2025-06-12 9:20:51 2028-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FRANCIS TAMALE
ID: UNCST-2025-R018057
 Institutional Quality, the Macroeconomy and Tax Revenue Growth in Uganda
REFNo: SS3891ES

To evaluate how institutional quality and macroeconomic factors jointly influence tax revenue growth in Uganda, and to assess the mediating role of tax compliance in these relationships
 Uganda 2025-06-12 14:30:49 2028-06-12 Social Science and Humanities Non-Clinical Trial Degree Award
JOAN ATURINDA
ID: UNCST-2025-R017847
 BUSINESS PROCESS REENGINEERING AND ORGANISATIONAL PERFORMANCE OF SMALL AND MEDIUM ENTERPRISES IN MBARARA CITY AND BUSHENYI DISTRICT.
REFNo: SS3878ES

The general objective of this study is to investigate the relationship between business process reengineering and organisational performance of SMEs. specific objectives; To examine the effect of information technology capabilities on organisational performance of SMEs. To examine the relationship between organisational structure and organisational performance of SMEs. To determine the relationship between organisational readiness for change and organisational performance of SMEs. To measure the moderation effect of ownership on the relationship between business process reengineering and organisational performance of SMEs.
Uganda 2025-06-12 14:28:19 2028-06-12 Social Science and Humanities Non-Clinical Trial Degree Award
John Semazzi Baptist
ID: UNCST-2025-R016637
 Elucidating Agroforestry Practices' Influence on Smallholder On-farm Species Diversity and Food Security in Rakai and Kitgum Districts of Uganda
REFNo: SS3882ES

General objective: To generate knowledge on the contributions of agroforestry practices to smallholder on-farm species diversity and food security among smallholder farmers in Rakai and Kitgum districts of Uganda Specific objectives: 1.To assess the level of adoption of agroforestry practices among smallholder farmers in Rakai and Kitgum districts. 2. To examine the contribution of agroforestry practices to household food security in Rakai and Kitgum districts. 3. To identify the factors underpinning adoption of agroforestry practices among smallholder farmers in Rakai and Kitgum districts. 4. To investigate the effect of agroforestry practices on on-farm species diversity in Rakai and Kitgum districts.
Uganda 2025-06-12 14:26:39 2028-06-12 Social Science and Humanities Non-Clinical Trial Degree Award
Samuel Balamaga Ssanyu
ID: UNCST-2023-R005693
 ADOLESCENT RISKY SEXUAL BEHAVIORS, EFFECT OF PEER-LED SEXUALITY EDUCATION, AND SECONDARY SCHOOL PREPAREDNESS FOR THE SEXUALITY EDUCATION NEEDS OF ADOLESCENTS IN MASAKA CITY
REFNo: HS5938ES

3. To examine the preparedness of secondary schools to respond to the sexuality education needs of school-going adolescents in Masaka City, Uganda.,2. To evaluate the effect of peer-led sexuality education on the sexual behaviors of adolescents attending secondary schools in Masaka City, Uganda.,1. To determine the prevalence of risky sexual behaviors and associated factors among adolescents attending secondary schools in Masaka City, Uganda., To determine the prevalence of risky sexual behaviors, the effect of peer-led sexuality education, and the preparedness of secondary schools in Masaka City, Uganda to respond to the sexuality education needs of school-going adolescents.,
 Uganda 2025-06-10 14:35:14 2028-06-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
 Performance evaluation of the Truenat® MPX Tests to detect Mpox in Uganda
REFNo: HS5956ES

1) To compare the sensitivity and specificity of the Truenat® MPX assay with BioPerfectus Monkeypox Virus Real Time PCR Kit / Altona Fexstar in detecting Mpox cases in Uganda.
2) To assess the overall diagnostic accuracy, including the rate of false positives and negatives, of the Truenat® MPX assay compared to the RT-PCR standard.
 Uganda 2025-06-10 14:33:48 2028-06-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mark Kaddu
ID: UNCST-2025-R017147
 IMPACT OF ELECTRONIC LOGISTICS MANAGEMENT INFORMATION SYSTEM (eLMIS) ADOPTION AND UTILIZATION ON SUPPLY CHAIN PERFORMANCE IN PUBLIC HEALTH FACILITIES IN GREATER KAMPALA METROPOLITAN AREA.
REFNo: HS5793ES

General Objective To assess the impact of eLMIS adoption and utilization on the performance of health supply chains in public health facilities in Greater Kampala Metropolitan Area Specific Objectives 1. To determine the level of adoption and utilization of eLMIS in public health facilities in Greater Kampala Metropolitan Area. 2. To investigate the impact of eLMIS adoption and utilisation on health supply chain key performance indicators in Greater Kampala Metropolitan Area public health facilities.
 Uganda 2025-06-05 9:11:13 2028-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Barbara Castelnuovo
ID: UNCST-2019-R000802
 HEALTHy aging with HIV in Uganda cohort: screening for non-communicable diseases and geriatric syndromes. (HEALTHiv)
REFNo: HS5803ES

Specific Aim 1. To document endpoints of NCDs (and their risk factors) that are common in older PLWH exposed to the currently recommended ART regimens, particularly cardio vascular disease, renal disease (proteinuria and creatinine clearance), metabolic syndromes and bone loss (calcaneal ultrasound) and their risk factors.
Specific Aim 2. To document frailty and other geriatric syndromes in older PLWH, frailty and geriatric syndromes progression and risk factors
Uganda 2025-06-05 9:08:20 2028-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Maren Mickeler
ID: UNCST-2024-R003691
 Understanding supportive leadership in organizations
REFNo: SS3820ES

This study investigates how supportive leadership influences bottom-up knowledge sharing within organizations. Although frontline employees often have valuable insights, their knowledge frequently fails to reach upper management—often due to supervisory barriers such as strict hierarchies, micromanagement, or a lack of psychological safety.

To address this, the research team is conducting a randomized controlled trial (RCT) in collaboration with Centenary Bank Uganda. The intervention involves providing supportive leadership training to supervisors (middle managers) in randomly selected bank branches. Control branches will not receive the training during the study period.

Our main objective therefore is to test and measure the effect of supportive leadership training on bottom-up knowledge sharing and other organizational outcomes in a real-world organizational setting.
 Germany 2025-06-05 8:57:07 2028-06-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Paul Mwanja
ID: UNCST-2024-R002501
 ADMINISTRATIVE VARIABLES AND DISCIPLINE OF ACADEMIC STAFF IN PUBLIC UNIVERSITIES IN KAMPALA, UGANDA
REFNo: SS3830ES

i. To investigate the relationship between staffing and academic staff discipline in public universities in Kampala, Uganda.
ii. To examine the relationship between organizing and academic staff discipline in public universities in Kampala, Uganda.
iii. To analyse the relationship between directing and academic staff discipline in public universities in Kampala, Uganda.
iv. To assess the relationship between control and academic staff discipline in public universities in Kampala, Uganda.
v. To investigate the relationship between the intervening variables and academic staff discipline in public universities in Kampala, Uganda

 Uganda 2025-06-05 8:55:27 2028-06-05 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph Kirabira
ID: UNCST-2019-R001427
 A workshop-based learning for Medical Officers, Senior House Officers, Psychiatrists, and Pediatricians (Medical Doctors) in the use of medication in treating child and adolescent mental health conditions in Uganda.
REFNo: HS5877ES

Main Objective
1. To assess the current level of knowledge, skills, and practice of prescribing medications to address children and adolescents’ mental health conditions among medical doctors in Eastern Uganda.
2. To develop, evaluate and administer a workshop-based training materials on the use of medication in treating child and adolescent mental health conditions in Eastern Uganda.
Specific Objectives
1. To explore the knowledge, skills and practices of medical doctors regarding use of medications in treating child and adolescent mental health conditions in Eastern Uganda.
2. To develop and implement a workshop-based training for 50 medical doctors working with children and adolescents in Eastern Uganda.
3. To conduct an evaluation of the training programme among the medical doctors.
 Uganda 2025-06-05 8:49:35 2028-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
 Cluster randomized trial of intermittent preventive treatment of malaria in school-age children to improve the health of students and decrease community transmission (CRITICal)
REFNo: HS5878ES

To estimate the effectiveness of IPTsc with DP in reducing community level malaria burden. We will test the hypothesis that malaria incidence will be lower in intervention clusters (randomised to receive IPTsc) than in control clusters (randomised to not receive IPTsc).
 Uganda 2025-06-05 8:47:33 2028-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Amina Hassan
ID: UNCST-2025-R017065
 A STUDY OF CHILD MOTHERS’ EXPERIENCES ON COMMUNITY-BASED REHABILITATION IN MBALE DISTRICT, EASTERN UGANDA
REFNo: SS3834ES

Main objective/ purpose
The major objective of the study is to highlight the experiences of the child mothers' community-based rehabilitation services in Mbale District, Uganda.
Specific Objectives
1. To identify the challenges that the child mothers experience
2. To establish the support services they received from the community during pregnancy
3. To examine the support services they received from the community after delivery

 Uganda 2025-06-05 8:44:56 2028-06-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Aldomoro Burua
ID: UNCST-2024-R002082
 Characterization and treatment outcomes of asymptomatic pulmonary tuberculosis from community screening in Uganda
REFNo: HS5744ES

1) To assess the factors associated with asymptomatic compared with symptomatic pulmonary tuberculosis
2) To determine the infectiousness of asymptomatic compared with clinical pulmonary tuberculosis.
3) To evaluate the treatment outcomes of subclinical compared to clinical pulmonary tuberculosis.

 Uganda 2025-06-05 17:49:08 2028-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mary Namukisa
ID: UNCST-2025-R016850
 PARTICIPANT COMPENSATION IN MEDICAL RESEARCH: PRACTICES AND PERSPECTIVES OF INVESTIGATORS AND RESEARCH ETHICS COMMITTEES IN UGANDA
REFNo: HS5901ES

1. To identify the factors influencing research compensation in medical research in Uganda.
2. To explore the perspectives of investigators and REC members regarding research compensation in medical research in Uganda.
3. To determine the common research compensation practices utilized in medical research conducted in Uganda.
 Uganda 2025-06-05 17:17:52 2028-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Lorna Magara Florence
ID: UNCST-2025-R017918
 An Inquiry into the Phenomenon of Innovation Hubs in Uganda
REFNo: SS3976ES

1) To examine stakeholder perceptions and definitions of innovation hubs – Understanding how the founder, innovators, and university faculty conceptualize the role and function of innovation hubs within Uganda’s socio-economic context. 2) To identify the challenges and support mechanisms influencing stakeholder engagement – The study will assess the barriers and constraints that innovators, university faculty, and the founder face in their interactions with MoTIV, as well as the available resources that support innovation and entrepreneurship. 3) To analyze how collaboration influences the innovation culture at MoTIV Innovation Hub – The research will explore how partnerships among industry, academia, and government impact knowledge exchange, creativity, and technological advancement within the innovation hub.
Uganda 2025-06-05 17:04:33 2028-06-05 Social Science and Humanities Non-Clinical Trial Degree Award
Henry Ddungu
ID: UNCST-2019-R000966
 Feasibility and acceptability of red blood cell exchange among patients with sickle cell disease in Uganda.
REFNo: HS5971ES

1.To determine the availability and accessibility of RBCX in Uganda

2.To assess the willingness of patients with SCD to undergo therapeutic apheresis.

3. To evaluate the perceived benefits and drawbacks of therapeutic apheresis among patients with SCD.

4. To explore the potential barriers to the implementation and uptake of therapeutic apheresis in Uganda.
 Uganda 2025-06-02 17:42:17 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Steven  Puleh Sean
ID: UNCST-2021-R013722
 R21 MALARIA VACCINATION AMONG COMMUNITIES IN NORTHERN UGANDA DISTRICTS: UPTAKE, ADHERENCE TO SCHEDULE, ASSOCIATED FACTORS AND VACCINE EFFECTIVENESS
REFNo: HS5968ES

General objective To assess the uptake and adherence to vaccine schedules, associated factors, and the effectiveness of the R21 malaria vaccine in reducing test positivity rates, disease severity, and hospitalization rates among targeted children in selected communities in Northern Uganda. Specific objectives: 1. To assess the knowledge, attitude, and perceptions among communities of northern Uganda (Study I) 2. To assess the level of uptake (at least 1 dose) of malaria vaccine in children in children targeted for vaccination and its associated factors among communities in northern Uganda (Study II) 3. To evaluate adherence to the first three (3) malaria vaccine schedules for control of malaria in children under five years and associated factors in communities of northern Uganda (Study III) 4. To evaluate the effectiveness of malaria vaccine on test positivity rate, severity of the cases, mortality rates in the control of malaria one year after the introduction of the vaccine among children under five years in northern Uganda (Study IV)
Uganda 2025-06-02 17:40:17 2028-06-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Annet Namusisi Mary
ID: UNCST-2025-R017592
 Evaluation of the Uganda Public Health Bulletin impact
REFNo: HS5978ES

1. Determine the reach of the UPHB among national, district, and international stakeholders 2. Explore how readers perceive the relevance, quality, and usefulness of the UPHB 3. Assess Content Quality Using Standardized Scorecards 4. Analyze trends in digital engagement as measured by email open rates, click-through rates, and website traffic over the past five years 5. Evaluate the impact of the UPHB on public health decision-making within 9 years of existence
Uganda 2025-06-02 17:38:50 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
WALAKIRA FELIX JOSHUA
ID: UNCST-2023-R007993
 COMMUNITY PERCEPTIONS ON HERBAL MEDICINES USE IN TREATING UPPER RESPIRATORY INFECTIONS IN KATANGA SLUM, UGANDA; A WAY OF SPARING ANTIBIOTICS.
REFNo: HS5902ES

1. To explore prevailing perceptions and beliefs within the community regarding the efficacy of herbal medicines in treating upper respiratory infections.
2. To explore the perceived barriers and facilitators to the adoption of herbal medicines in treating Upper Respiratory Infections as a means of sparing antibiotics.
3. To determine the proportion of people in Katanga who have suffered from Upper Respiratory Infections.

 Uganda 2025-06-02 17:37:03 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Holly Parsons Jane Emily
ID: UNCST-2024-R002678
 Case Study: Exploring the Effectiveness of Village Health Teams in Uganda's 12 Refugee-Hosting District
REFNo: SS3874ES

The main objective on this research is to drive the narrative on a successful method of transition from humanitarian-funded to government ownership of health systems for refugees in low- and middle-income countries that depends on responsibility-sharing as part of the Global Compact on Refugees. The specific objective is to explore the effectiveness of Village Health Teams (VHTs) in Uganda's 12 refugee-hosting districts in preventing and treating human malaria by identifying key successes and key challenges of this health system, and then exploring how successes can be proliferated and how challenges can be mitigated.
Canada 2025-06-02 17:20:52 2028-06-02 Social Science and Humanities Non-Clinical Trial Degree Award
Amon Tayebwa
ID: UNCST-2024-R002098
 THE ANATOMICAL VARIATIONS AND DISTRIBUTION OF THE HUMAN CORONARY ARTERIES: A CADAVERIC STUDY AT MBARARA REGIONAL REFERRAL HOSPITAL IN SOUTH WESTERN UGANDA.
REFNo: HS6003ES

1.What are the different branching and dominance patterns of the human coronary arteries amongst unclaimed bodies at Mbarara Regional Referral Hospital?
2.What are the different patterns of origin of coronary arteries at the sinotubular junction amongst unclaimed bodies at Mbarara Regional Referral Hospital?
 Uganda 2025-06-02 17:17:36 2028-06-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Gloria Naome Aduku
ID: UNCST-2024-R015930
 IMPACT OF ANTHROPOGENIC ACTIVITIES (TOURISM) AND PARASITISM ON PHYSIOLOGIAL STRESS IN GORILLAS (Gorilla beringei beringei) IN BWINDI IMPENETRABLE NATIONAL PARK
REFNo: NS971ES

• To evaluate six different Enzyme Immunoassays (EIA) for quantifying fGCMs in mountain gorillas.
• To investigate the effect of bacterial metabolism and environmental factors on the stability of faecal glucocorticoid metabolite (fGCM) concentrations post-defaecation
• To examine variation in parasitic burden and fGCM concentrations of spatially separated mountain gorilla groups.
• To examine parasitic burden and fGCM concentrations of mountain gorillas during high and low tourism activity.
• To identify specific parasitic infections that correlate with elevated fGCM concentrations in mountain gorillas.

 Uganda 2025-06-02 17:16:50 2028-06-02 Natural Sciences Non-Clinical Trial Degree Award
AHEEBWA ROGGERS COLLINS
ID: UNCST-2025-R017036
 Tax Policies And Financial Performance Of Small & Medium Enterprises (SMEs) in Uganda: A Case Of SMEs in Kabale District
REFNo: SS3844ES

i. To examine the effect of tax compliance costs on the financial performance of small and medium enterprises in Kabale district
ii. To examine the effect of tax incentives on the financial performance of small and medium enterprises in Kabale district.
iii. To examine the effect of tax rates on the financial performance of small scale and medium enterprises in Kabale district.


 Uganda 2025-06-02 17:15:52 2028-06-02 Social Science and Humanities Non-Clinical Trial Degree Award
Kamya Moses
ID: UNCST-2020-R014203
 A case-control study to assess the effectiveness and safety of the R21/matrix-M malaria vaccine
REFNo: HS6009ES

To assess the Vaccine Effectiveness (VE) of R21/Matrix-M vaccine against severe malaria caused by Plasmodium falciparum.

To assess the Vaccine Effectiveness (VE) of the R21/Matrix-M vaccine against clinical malaria in high-transmission perennial areas caused by Plasmodium falciparum.

To assess if the R21/Matrix-M vaccine recipients are at an increased risk of death (all-cause).
 Uganda 2025-06-02 17:04:40 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 PROTOCOL FOR THE PERFORMANCE EVALUATION OF ALINITY M HIV-1 ASSAY USING DRIED BLOOD SPOT SPECIMENS HIV VIRAL LOAD ASSAY FOR WHO PREQUALIFICATION ASSESSMENT
REFNo: HS6061ES

• To assess the Alinity m HIV-1 DBS assay’s agreement with a cobas HIV-1 Quantitative nucleic acid test for use on the cobas 6800/8800 Systems (Roche Diagnostics GmbH) on clinical specimens, including:
o Quantitative assessment of bias, limits of agreement and correlation
o Misclassification above or below the clinical threshold (1000 copies/mL)
• To assess the analytical performance of the Alinity m HIV-1 assay using DBS:
o Precision (repeatability and within-laboratory reproducibility)
o Linear range on the main subtypes
o Limit of detection
o Cross-contamination
• To describe the operational characteristics and ease of use of the Alinity m HIV-1 assay using DBS and its suitability for use in countries with limited infrastructure.

 Uganda 2025-05-29 17:20:17 2028-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 STANDARDTM M10 HR-HPV: Evaluation of Clinical Performance and Usability in the hands of untrained users.
REFNo: HS6022ES

Demonstration of usability of the STANDARDTM M10 Hr-HPV assay. ,Demonstration of sample type equivalence for the STANDARDTM M10 Hr-HPV assay: ThinPrep® PreservCyt® Solution (Hologic) vs. BD SurePathTM Collection Vial (Becton, Dickinson and Company),Determination of the relative diagnostic sensitivity and specificity i.e. compared with the Roche Cobas HPV assay (used according to the current standard of care at the study site).,Determination of clinical accuracy i.e. absolute diagnostic sensitivity for CIN2+ and CIN3+ and absolute diagnostic specificity for ≤ CIN1.,To demonstrate the clinical performance of the STANDARDTM M10 Hr-HPV assay when used by healthcare professionals in a laboratory setting or health institution (i.e. intended use setting), the following objectives have been defined.,
 Uganda 2025-05-29 17:19:03 2028-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anatoli Mawanda
ID: UNCST-2024-R015927
 GENETIC AND MOLECULAR DETERMINANTS OF BREAST CANCER DISPARITY AMONG AFRICAN, AFRICAN AMERICAN AND WHITE POPULATIONS
REFNo: HS6015ES

To study the genetic, molecular, and biological regulators of breast cancer in Ugandan
women and compare them with African American and white women.
 Uganda 2025-05-29 17:17:31 2028-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christabel Gero Anyango
ID: UNCST-2025-R017108
 Perspectives of Child Domestic Workers and Their Employers: A Qualitative Study in Kampala, Uganda
REFNo: SS3860ES

• To establish patterns of entry into, exit out of and conditions of child domestic work in the Ugandan setting, including patterns that constitute human trafficking. Entry patterns will include decision making and influences to enter domestic work, while exit will encompass strategies used to transition to other work roles and the types of work roles entered following domestic work. • To understand employers’ perceptions of and views on child domestic workers, including reasons for recruiting younger workers, strategies to recruit CDWs, views on the benefits, drawbacks and development needs of younger workers, treatment and remuneration of CDWs, and awareness of laws and policies related to young workers, among others.
Kenya 2025-05-29 17:15:05 2028-05-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jeya Sushimitha Jawahar Kanth
ID: UNCST-2024-R016269
 Evaluating the Impact of Social Media Influencers on Tobacco Use Among Urban Youth in Africa: A Comparative Mixed Methods Study Across Kampala, Nairobi, and Lagos
REFNo: SS3850ES

Main Objective
1. To explore and compare the role of social media influencers in shaping tobacco use behaviors among urban youth (ages 18-29) residing in Kampala, Nairobi, and Lagos by examining tobacco use prevalence, influencer messaging, and youth perspectives.
Specific Objectives
1. To determine the prevalence of tobacco use among urban youth (18-29 years) in Nairobi, Lagos, and Kampala.
2. To assess the relationship between exposure to influencer content and tobacco use behaviors among urban youth.
3. To analyze the content and reach of pro-tobacco messages shared by social media influencers among the target youth population.
4. To investigate urban youth perceptions of how influencers impact their decisions and attitudes toward tobacco use.
 India 2025-05-29 17:14:22 2028-05-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Denis Nansera
ID: UNCST-2024-R004002
 Improving HIV testing among Children under five in Rural Uganda
REFNo: HS5829ES

The main objective of this study is to develop a traditional healer facilitated paediatric HIV testing program to improve access to paediatric HIV testing. To do this, we will first use qualitative study methods to determine factors that influence HIV testing among paediatric clients of TH and guide adaptation of the TH-facilitated HIV testing program for children. We will then implement a pilot study to evaluate offering paediatric HIV testing at traditional healer locations in southwestern Uganda.
 Uganda 2025-05-29 17:12:49 2028-05-29 Medical and Health Sciences Clinical Trial Non-degree Award
Nanyonga Elizabeth Monica
ID: UNCST-2025-R018232
 srd
REFNo: SIR516ES

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 Uganda 2025-05-27 9:30:38 2028-05-27 Engineering and Technology Clinical Trial Non-degree Award
Justine  Komunyena Tumusiime
ID: UNCST-2023-R008465
 “Exploring Acceptability: Expanding Family Planning Services in Pharmacies and drug shops in Uganda.”
REFNo: HS5733ES

a. To assess the acceptability of family planning including implant provision through pharmacies and drug shops among key stakeholders in Uganda.
b. To examine the role of non-monetary incentives (e.g., training, certification, recognition) in motivating pharmacy and drug shop operators to provide FP services.
c. To explore the willingness and capacity of pharmacy and drug shop providers to comply with government reporting requirements for FP service provision.
d. To identify perceived potential facilitators and challenges to the successful implementation of implant provision in pharmacies and drug shops in Uganda.

 Uganda 2025-05-27 11:03:29 2028-05-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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"A prosperous Science and Technology Led Ugandan Society."

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