Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
FRANK MULINDWA
ID:
Glucose metabolism changes in HIV patients starting dolutegravir based antiretroviral treatment in Uganda
REFNo: HS1032ES

1) To determine the incidence and predictors of diabetes at week 48 in Ugandan HIV patients initiating dolutegravir.
2) To describe temporal changes in insulin resistance, pancreatic beta cell function, body mass index and blood glucose in Ugandan HIV patients on dolutegravir for 48 weeks.
3) To determine the effect of DTG on intracellular magnesium levels in Ugandan HIV patients on dolutegravir for 48 weeks.
4) To compare insulin kinetics in patients who develop diabetes while on dolutegravir and those that don’t in Ugandan HIV patients.
5) To determine the difference in DTG pharmacokinetics in HIV positive patients with incident hyperglycemia and those without in Ugandan HIV patients.

 Uganda 2021-01-20 2024-01-20 Medical and Health Sciences Non-degree Award
Proscovia Nabunya
ID: UNCST-2019-R000970
 SAY NO TO STIGMA”: Making Mental Health Visible Among School-Going Children in Rural Uganda
REFNo: SS637ES

The objective of this proposed study is to develop a set of new age-appropriate, culturally relevant signage and messaging around mental health and stigma for this study. The visual solutions will be developed through a set of extensive hands-on creative workshops and focus groups with children as well as school administrators and teachers working in one primary school in the Masaka region of Uganda. After visual and message development, the visuals will be presented to a different group of students within the school to gather feedback on their effectiveness and clarity in portraying mental health and stigma.
 Uganda 2021-01-20 2024-01-20 Social Science and Humanities Non-degree Award
Polycarp Komakech
ID:
Incentivizing Action to Reduce Air Pollution and Susceptibility to COVID-19
REFNo: SS667ES

The main objective is to investigate a number of practical and scalable strategies to reduce waste burning through voluntary behavioral change and thereby reduce the exposure of residents to harmful air pollution. The specific objectives are (a) to investigate whether the provision of information about the link between air pollution and the chances of contracting and dying from COVID-19 can spur action to stop waste burning, (b) to test the efficacy of a novel design where social competition that is not imposed top-down but is organized horizontally can help leaders to organize communities for positive action towards reducing waste burning.
Uganda 2021-01-20 2024-01-20 Social Science and Humanities Non-degree Award
SHAFIC MAKUMBI
ID:
Voluntary Consent to Research on Children: A sub-study of the CHAPAS-4 and ODYSSEY Trial
REFNo: SS677ES

1.2 Overall objective
The aim of this study is to assess parental perception of voluntariness of consent in Paediatric HIV clinical trials and associated factors.

1.4 Specific objectives
1.4.1. To describe the process in which parents and guardians consent for their children to be enrolled in two pediatric HIV Clinical Trials.
1.4.2. To measure the level of perceived voluntariness of consent using the voluntariness ladder
1.4.3. To identify the social demographic, situational and external control factors that influence parental perception of the voluntariness of their consent

 Uganda 2021-01-20 2024-01-20 Social Science and Humanities Degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 Impact of Masks on Community Spread of COVID-19: Evidence from Uganda
REFNo: HS1124ES

2.1 General Objective

The aim of this study is to provide policy makers with the first population-based estimate of the extent to which face coverings reduce the spread of SARS-CoV-2. We also intend to provide evidence to the Ministry of Health in Uganda (and public health officials more generally) with evidence about effective communication and education tools for increasing the proper use of masks in the general population.


2.2 Specific Aims

The specific objectives of our study are as follows:

Aim 1: To test whether free mask distribution increases the proper use of masks in intervention communities
Aim 2: To test whether combining free mask distribution with education and communication about masks and COVID-19 increases the proper use of masks in intervention communities Aim 3: To evaluate whether increased mask use affects seroprevalence of SARS-CoV-2
Aim 4: To evaluate potential spillovers, or whether higher mask use in intervention communities affect mask use and probability of infection in neighboring non-intervention communities

 Uganda 2021-01-20 2024-01-20 Medical and Health Sciences Non-degree Award
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