Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Betty Nalikka
ID: UNCST-2024-R016316
Ecological and epidemiological dynamics of viruses in Ugandan bat populations.
REFNo: NS969ES

1. To determine the prevalence, diversity and genetic variation of viruses in different bat species, considering both time and space.
2. To use host density, distribution, and pathogen prevalence to develop models that can be used to forecast spillover risks from bats to other animals, including humans.
3. To investigate the duration of immunity to viruses in bats by sampling individuals across different age groups over time.

Uganda 2025-05-23 13:58:46 2028-05-23 Natural Sciences Non-Clinical Trial Degree Award
Muge Cevik
ID: UNCST-2022-R011548
Improving surveillance and detection of MPXV in Uganda
REFNo: SS3940ES

• To determine seroprevalence of MPXV among people living with HIV in Uganda • To elucidate the risk factors associated with infection.
UK 2025-05-23 13:57:06 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
ochuga patrick olanya
ID: UNCST-2024-R015276
PREVALENCE, AND FACTORS ASSOCIATED WITH CHORIOAMNIONITIS AMONG WOMEN ADMITTED WITH PPROM AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS5949ES

To determine the prevalence and factors associated with chorioamnionitis among women admitted with PROM at MRRH
Uganda 2025-05-23 13:54:31 2028-05-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Nina Rugambwa Olivia
ID: UNCST-2019-R000213
SAFEGUARDING MENTAL HEALTH OF CHILDREN WITH PHYSICAL DISABILITIES IN INCLUSIVE PUBLIC PRIMARY SCHOOLS: A CASE OF KAMULI DISTRICT, UGANDA
REFNo: SS3894ES

To explore the coping strategies of children with physical disabilities and their relationship to mental well-being in schools in Kamuli District.,3. To examine mental health safeguarding measures and their implementation in inclusive government primary schools in Kamuli District ,2. To document cultural beliefs and practices that promote mental health and inclusiveness of children with disability at school and in their communities in Kamuli District,1. To determine the mental health status of children with physical disabilities in government-inclusive primary schools in Kamuli district,This study seeks to create awareness about the mental health of children with disabilities and enhance their safety in inclusive government primary schools in Kamuli district.,
Uganda 2025-05-23 13:43:10 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Phiona Bukirwa
ID: UNCST-2022-R009880
Colorectal Cancer Biology: Clinicopathologic characteristics, Mismatch Repair (MMR) status and prognostic factors of colorectal carcinoma in Sub-Saharan Africa
REFNo: HS5980ES

1. To determine the prevalence of Mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) in FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.
2. To assess the association between histopathological parameters like tumor grading, tumor type, frequency of tumor infiltrating lymphocytes and tumor budding in microsatellite instability-high (MSI-H) FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.
3. To assess the association of clinical finding (age, sex, TNM stage, site of tumour) with mismatch repair status in FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.
4. To assess the prevalence of BRAF and KRAS mutation in FFPE tissue blocks of colorectal carcinoma in Sub-Saharan Africa.

Uganda 2025-05-23 13:40:32 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Godfrey Kubiriza Kawooya
ID: UNCST-2024-R003138
Eco-innovative technologies for improved nutrition, sustainable production and marketing of Agro-ecological food products in Africa (INNOECOFOOD)
REFNo: A574ES

Main objective of the baseline study
The main objective of the baseline study is to scope community indigenous knowledge, gaps, attitudes and aquaculture practices in local lakes and rivers (living labs) on production, processing, marketing and consumption of aquaculture value chains (fish and selected Spirulina species) and insect species in Uganda.

Specific Objectives
i.To determine the current community Knowledge on sustainable production, processing and consumption of fish, spirulina and insects as food and feed.
ii.To determine the current community Attitude on sustainable production, processing and consumption of fish, spirulina and insects as food and feed.
iii.To determine the current community Practices on sustainable production, processing and consumption of fish, spirulina and insects as food and feed.
iv.Assess how socio-demographics factors influence the production, processing and consumption of fish, spirulina and insects as food and feed.

Uganda 2025-05-23 13:39:33 2028-05-23 Agricultural Sciences Non-Clinical Trial Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
Genetic Associations of INfertility in Africa (The GAIN Study)
REFNo: HS5967ES

The GAIN study aims to identify genetic variants associated with unexplained primary infertility in African women
Uganda 2025-05-23 13:37:00 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
Uganda Population-based HIV Impact Assessment (UPHIA 2024-2025)
REFNo: HS5817ES

The primary objectives of UPHIA 2024-2025 are to:
1) Estimate the national and regional prevalence of HIV viral load suppression (VLS – defined as HIV RNA <1000 copies/milliliter(mL) in adults ages 15 years or older in the general population.
2) Estimate the prevalence of HIV at the national and regional level
3) Assess progress towards the UNAIDS 95- 95- 95 targets at the national and regional level

The secondary objectives of the survey are to:
1) Estimate the HIV incidence at the national level
2) Estimate the prevalence of HIV-related risk behaviors, knowledge, and attitudes
3) Establish the behavioural and demographic determinants of HIV prevalence and incidence
4) Determine the exposure to, uptake of and barriers to access to HIV-related services
5) Estimate the prevalence of elevated blood pressure, elevated blood glucose and obesity among the general population and people living with HIV
6) Assess the facilitators of and barriers to viral load suppression among people living with HIV on ART in two regions with the lowest VLS, based on the UPHIA 2020-21 survey findings.

Uganda 2025-05-23 13:34:26 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DAVID KITYA
ID: UNCST-2022-R009620
Analysis of the out-of-pocket costs of neurosurgical care in Uganda
REFNo: HS5875ES

3. To assess the socioeconomic impact of neurosurgical care on patients and their families/caregivers in Uganda, and to identify the key cost-related factors contributing to this burden within the local context.,2. To ascertain the proportion of patients experiencing catastrophic and impoverishing healthcare expenditure due to their neurosurgical care.,1. To determine the direct and indirect out-of-pocket costs borne by patients receiving neurosurgical care.,The main objective of this study is to quantify the OOP expenditure costs for patients receiving neurosurgical care in Uganda to estimate the proportion of patients experiencing CHE,
Uganda 2025-05-23 13:30:41 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MARTHA GIMONO
ID: UNCST-2024-R016208
The Readiness of Emerging Adults (18-25 years) Living with Type 1 Diabetes to Transition from Pediatric to Adult Healthcare in Jinja District - Uganda.
REFNo: HS5871ES

1. To develop transition screening tools for emerging adults living with T1D in Jinja District, Uganda.
2. To understand facilitators of transition readiness among emerging adults living with T1D in Jinja District, Uganda.
3. To determine the level of transition readiness among emerging adults living with T1D in Jinja District, Uganda

Uganda 2025-05-23 13:28:29 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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