Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Nelson Sewankambo K
ID: UNCST-2020-R014578
Evaluation of an Information Management and Communication System for Population-wide Point-of-Care Infant Sickle Cell Disease Screening (SIMCS)- A Cluster Randomized Trial
REFNo: HS6567ES

(ii) To evaluate the impact of the SCD SIMCS on access to screening and care and outcomes of children with SCD,
Uganda 2025-12-05 18:30:02 2028-12-05 Medical and Health Sciences Clinical Trial Non-degree Award
Julius Ssendiwala
ID:
EVALUATION OF HIV INTEGRATION INTO ROUTINE CARE AT HEALTH FACILITIES IN UGANDA: LESSONS LEARNT FROM -THE COVID-19 HIV SERVICE DELIVERY ADAPTATIONS AND THE US PRESIDENT EXECUTIVE ORDERS
REFNo: HS6720ES

1. To document the health system adaptations that occurred during the COVID-19 pandemic, and the recent US President Executive Orders and how are they are being utilized for current HIV integration efforts?
2. To document the various models of HIV integration currently being implemented, and the factors that facilitate or hinder their successful implementation
3. To assess the uptake, feasibility, and acceptability of integrating HIV services into routine healthcare services

Uganda 2025-12-03 18:46:20 2028-12-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
VALIDATION OF AN OFFLINE DEEP – LEARNING AI MODEL FOR ESTIMATING FVC AND FEV? FROM CHEST X?RAYS IN A RESOURCE?LIMITED UGANDAN CLINICAL SETTING.
REFNo: HS6703ES

Primary Objective
To evaluate the accuracy of an offline, deep-learning AI model in estimating forced vital capacity (FVC) and forced expiratory volume in one second (FEV?) by comparing AI-predicted values against spirometry-measured values.

Secondary Objective
To determine the agreement between AI-derived and spirometry-derived FEV?/FVC ratios, and assess its utility for identifying airflow obstruction (i.e., FEV?/FVC?
Uganda 2025-12-01 22:01:17 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ombeva  Malande Oliver
ID: UNCST-2024-R004335
Exploring Factors Influencing COVID-19 Vaccination Uptake: A Qualitative Study in Uganda
REFNo: SS4582ES

To explore the factors and contextual differences that influenced COVID-19 vaccination uptake in Uganda, to compare these with experiences in Burundi and Rwanda, and to identify key predictors and opportunities for regional learning
Kenya 2025-12-01 21:44:17 2028-12-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
STELLA NABIRYE
ID: UNCST-2024-R003637
Evaluation of outcomes of anticoagulation and factors associated with Time in Therapeutic Range among Rheumatic heart disease patients on vitamin K antagonists attending care at the Uganda Heart institute
REFNo: HS6728ES

General objective
To evaluate the outcomes of anticoagulation and factors associated with time in therapeutic range among Rheumatic heart disease patients on vitamin K antagonist attending care at Uganda Heart Institute

specific objectives
1.To determine the clinical outcomes of anticoagulation among Rheumatic heart disease patients on vitamin K antagonists attending care at Uganda Heart Institute

2.To determine the factors associated with time in therapeutic range among Rheumatic disease patients on vitamin K antagonists attending care at Uganda Heart Institute

3.To explore patients’ attitudes and knowledge on the use of vitamin K antagonists among Rheumatic heart disease patients attending care at Uganda Heart Institute

4.To explore clinicians’ perception of the use of vitamin K antagonists in managing patients with Rheumatic heart disease attending care at Uganda Heart Institute
Uganda 2025-12-01 21:35:22 2028-12-01 Medical and Health Sciences Non-Clinical Trial Degree Award
ATUHAIRE JUSTUS
ID: UNCST-2024-R004914
Improving the quality of face sheet completion at Mulago National Referral Hospital
REFNo: HS6627ES

1. To determine the proportion of face sheet that are not complete at Mulago National Referral Hospital. 2. To identify the factors that contribute to failure of doctors to complete face sheet at Mulago National Referral Hospital. 3. To identify the measures that can be put forward towards completion of face sheet at Mulago National Referral Hospital.
Uganda 2025-12-01 21:28:40 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mirembe SarahAngella
ID: UNCST-2025-R021000
Influence of Women's Participation In The Rice Value Chain on Household Dietary Diversity in Eastern Uganda
REFNo: SS4586ES

1. To examine the extent of women’s participation in the rice production, processing, and marketing activities within selected rice-oriented households in Namasagali sub-county, Eastern Uganda. 2. To identify the institutional factors that influence women’s participation as rice value chain actors at the household level. 3. To assess the dietary diversity of rice-oriented households in Namasagali sub-county, Eastern Uganda. 4. To establish a relationship between women’s participation and household dietary diversity.
Uganda 2025-12-01 21:16:33 2028-12-01 Social Science and Humanities Degree Award
Nambusi Kyegombe Davina Ndibalekera
ID: UNCST-2022-R009559
Ethics in Action in Low and Middle-Income Settings (EALMIC) Study: Challenges faced by researchers in applying ethical principles in Uganda
REFNo: SS4624ES

This aim of this study is to explore the emotional and psychological challenges faced by health researchers in Uganda working with vulnerable populations and on sensitive topics, in order to inform ethical guidelines and support strategies for enhancing researchers' well-being.
The study will be guided by five main objectives:
1. To explore researchers’ experiences of conducting research with vulnerable populations and on sensitive topics.
2. To explore how researchers’ experiences affect their wellbeing.
3. To identify coping and support mechanisms used by researchers to respond to their experiences.
4. To assess the ethical challenges faced when working with vulnerable populations.
5. To explore researchers’ perceptions of the role of cultural factors, including ubuntu principles, patriarchal gender norms, respect for elders and social hierarchies, on researchers’ experiences.

Uganda 2025-12-01 21:13:31 2028-12-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Atwebembeire John Mushomi
ID: UNCST-2025-R022006
Evaluation of the ASRH Gatherings for Young Mother Gardeners Program
REFNo: SS4584ES

To assess the short- and medium-term impacts of the ASRH Gatherings and integrated livelihood support on young mothers in Kasese District.1. i. Examine how the program addresses challenges faced by adolescent mothers. 2. ii. Document transformative changes in participants’ lives, including aspirations, health, and livelihoods. 3. iii. Provide evidence-based recommendations for strengthening and scaling the program.
Uganda 2025-12-01 21:05:46 2028-12-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Doreen Nakagaayi
ID: UNCST-2023-R006587
Rheumatic Heart Disease among Pregnant women in Northern Uganda: Prevalence, Impact on Pregnancy Outcomes and Strategy for Early Identification.
REFNo: HS6717ES

General Objectives
To determine the prevalence of RHD in pregnancy in Northern Uganda, the maternal and fetal outcomes and use this data to develop and validate clinical risk scores that predict presence of RHD in pregnancy and those at increased risk for adverse maternal outcomes.
Specific Objectives
Objective 1
A. To determine the prevalence of RHD among pregnant women in a community setting in Northern Uganda.
B. To design a diagnostic risk score that predicts presence of RHD in early pregnancy in Northern Uganda
Objective 2
A. To determine the maternal, and fetal outcomes of pregnant women with RHD in a community setting in Northern Uganda.

Uganda 2025-12-01 20:59:51 2028-12-01 Medical and Health Sciences Non-Clinical Trial Degree Award
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