Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,902
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Christopher Turyatunga Bernard
ID: UNCST-2023-R006842
 Drivers, profiling and drugs resistance effects, outcomes and cost-effectiveness of diagnostic and Syndromic interventions among urogenital discharging patients in southwestern Uganda
REFNo: HS3796ES

Establish the aetiology and sensitivity profile of urogenital discharges among patients in south western Uganda. ,5. Evaluate the Comparative cost effectiveness of diagnostic and Syndromic approaches in the management of patients with urogenital discharges in south western Uganda.,4. Compare the treatment outcomes between syndromic and diagnostic approaches in the management of patients with urogenital discharges in south western Uganda.,3. Determine the drivers of drugs resistance among patients with urogenital discharges in south western Uganda. ,2. Determine the effect of drugs’ resistance on the management of patients with urogenital discharges in south western Uganda.,This study is aimed at establishing the drivers, profiling and effect of drugs resistance, comparative treatment outcomes and cost-effectiveness of diagnostic and Syndromic interventions on patients with urogenital discharges in southwestern Uganda, and it is a parallel randomized intervention at STI clinics of Kabale and Mbarara Regional Referral Hospitals and Kisiizi Mission Hospital.,
 Uganda 2024-04-26 9:21:22 2027-04-26 Medical and Health Sciences Clinical Trial Degree Award
David Kabugo
ID: UNCST-2023-R005971
 An Evaluation of the Caring for Caregiver (CFC) Intervention on caregiver emotional wellbeing, social support, and parenting stress in two rural districts of Uganda
REFNo: SS2385ES

1. To determine whether exposure to Caring for Caregiver (CFC) standardized training and supervision results in improvements in FLW counselling capacities and leads to fidelity in the application of CFC skills, tools, activities.
2. To determine whether exposure to CFC skills, tools, activities result in positive changes to emotional-wellbeing, social support and parenting stress in an intervention group relative to a comparison group.
3. To assess whether FLW emotional wellbeing, social support, and perceived stress, before, during and after training, implementation and supervision, influences caregiver and/or FLW outcomes.

 Uganda 2024-04-26 9:17:45 2027-04-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Louis Kamulegeya Henry
ID:
Assessing the role of micro-nutrient deficiency and Immune system dysfunction among HIV-positive adults with pulmonary Tuberculosis at a public health facility in Uganda.
REFNo: HS3933ES

To determine the relationship between micro and macro nutrient status with pulmonary tuberculosis treatment response (symptom improvement).,To determine the association between micro and macro nutrient status and TB specific Immune responses among HIV infected TB patients,To assess the association between macro and micro nutrient status with severity of pulmonary tuberculosis among HIV/TB infected patients,To determine the levels of macro and micro nutrients among HIV-infected pulmonary tuberculosis patients at a public health facility,To assess how nutritional status (macro and micro) among HIV-positive patients co-infected with pulmonary tuberculosis correlates with the severity of symptoms, immune response and treatment outcome at a public health facility in Uganda,
 Uganda 2024-04-26 9:15:09 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sarah Zalwango Karen
ID: UNCST-2021-R005660
 Qualitative assessment of Facilitators and barriers to using wearable GPS watches as a device for collecting research data.
REFNo: SIR326ES

The objective is to assess the facilitators and barriers to wearing a GPS watch among individuals with no previous infection of M. tuberculosis in Kampala, Uganda. ,
 Uganda 2024-04-26 9:12:25 2027-04-26 Engineering and Technology Non-Clinical Trial Non-degree Award
Mercyline Ong'ayo Jerusa
ID:
Antecedents to participation and performance of collective action initiatives amongst the smallholder farmers in Northern Uganda
REFNo: SS2507ES

To contribute to improved performance of farmer organizations by unraveling participation dynamics in collective action initiatives undertaken by FOs in Northern Uganda., iv. To determine the influence of farmer participation and socio-economic environment on the perceived performance of CAIs.,iii. To determine the influence of farmer motivation on participation in CAIs provided by farmer organizations. ,ii. To analyze the relationship between entrepreneurial orientation and farmer participation in CAIs.,i. To determine the relationship between socio-economic environment and farmer participation intensity in CAIs provided by farmer organizations. ,
 Kenya 2024-04-26 9:09:58 2027-04-26 Social Science and Humanities Non-Clinical Trial Degree Award
Arianna Pacifico
ID:
Political Economy Analysis of Refugee Education Financing within the Context of the Inclusion Agenda
REFNo: SS2571ES

To support international donors and refugee hosting education systems achieve adequate and sustainable financing for refugee education in national systems.,
 USA 2024-04-26 9:08:09 2027-04-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Joan Atim
ID:
Prevalence of Lower Extremity Arterial Disease and Associated Factors Among HIV-infected Adults on Antiretroviral treatment at Mildmay Uganda.
REFNo: HS2912ES

ii. To determine the factors associated with lower extremity arterial disease among HIV-positive patients on ART at Mildmay Uganda.,i. To determine the prevalence of lower extremity arterial disease among HIV-positive patients on ART at Mildmay Uganda.,To determine the prevalence and factors associated with lower extremity arterial disease among HIV-positive patients on ART at Mildmay Uganda.,
 Uganda 2024-04-26 9:04:25 2027-04-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Yahaya Gavamukulya
ID: UNCST-2019-R001017
 Formulation and Pre-clinical Evaluation of Herbal Toothpaste/ Mouth Wash for Management of Oral Diseases: STI-OP Dental Solutions Project
REFNo: HS4022ES

General objective/ Purpose of the study To formulate a herbal toothpaste/ mouth wash and undertake preclinical studies on its use in management of oral diseases Specific objectives 1. To formulate herbal toothpaste/ mouth wash from extracts of selected plants for management of oral diseases. 2. To evaluate the organoleptic and physical properties of the formulated herbal toothpaste / mouth wash as per specified standards. 3. To evaluate the antimicrobial activity of the formulated herbal remedy against selected oral pathogens, Streptococcus mutans and Staphylococcus aureus. 4. To produce one batch of the fully tested herbal remedy for subsequent field testing.
Uganda 2024-04-22 6:35:14 2027-04-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Michael Okot
ID: UNCST-2023-R005793
 FACTORS INFLUENCING ACCESS AND UTILISATION OF ELIMINATION OF MOTHER TO CHILD TRASMISSION (EMTCT) OF HIV SERVICES IN ACHOLI SUB REGION, UGANDA.
REFNo: HS3996ES

To determine the enabling factors affecting access and utilization of the EMTCT services by the pregnant and breastfeeding women in Acholi Sub Region, Uganda.,To identify the predisposing factors affecting access and utilization of the EMTCT services by the pregnant and breastfeeding women in Acholi Sub Region, Uganda.,To explore and analyses the factors influencing the access and utilisation of the EMTCT services by pregnant women including those in high-risk groups in Acholi Sub Region.,
 Uganda 2024-04-22 6:25:27 2027-04-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Justine  Komunyena Tumusiime
ID: UNCST-2023-R008465
 STAKEHOLDER ACCEPTABILITY AND USABILITY OF A MICROARRAY PATCH FOR PEDIATRIC ANTIRETROVIRAL TREATMENT IN UGANDA
REFNo: HS3928ES

To observe and interview stakeholders who would be potential users of the pediatric ARV MAP in Uganda
 Uganda 2024-04-22 6:21:28 2027-04-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Bridges2Scale: Testing Implementation Strategies for an intervention among young people affected by AIDS
REFNo: SS2488ES

Bridges2Scale will use a two-arm Hybrid III effectiveness-implementation cluster randomized clinical trial, where we will compare two multifaceted strategies (standard vs. enhanced) for scaling the Bridges interventions (consisting of financial literacy training, peer mentorship, family income-generating , and youth development accounts). The standard implementation strategy has been applied in our prior and ongoing studies and involves educational meetings that prepare staff members to deliver Bridges with minimal disruption to site workflow. This will be compared to an enhanced strategy that will be developed using Implementation Mapping, a systematic protocol for developing implementation strategies using theory, evidence, and stakeholder input. Aim 1: Compare the implementation effectiveness of the standard implementation strategy vs. an enhanced implementation strategy. Aim 2: Determine the clinical effectiveness of Bridges implemented via a standard vs. enhanced implementation strategy. Aim 3: Explore implementation processes, mechanisms, and determinants. Aim 4: Compare the cost and cost-effectiveness of the two implementation strategies.
 Uganda 2024-04-19 18:42:54 2027-04-19 Social Science and Humanities Clinical Trial Non-degree Award
Margaux Dupuis
ID:
Assessing the Role of Maternal Social Network Inheritance in the Social Integration of Juvenile Vervet Monkeys (Chlorocebus pygerythrus)
REFNo: NS802ES

I aim to answer the questions: how do maternal dominance rank, age, social network position, and mother-offspring proximity relate to the proximity and grooming networks of their juveniles? Does this differ by offspring sex and/or age?
I hypothesized that maternal social network inheritance occurs and differs by sex and age in vervet monkeys because of (1) mother-offspring proximity, (2) influences of maternal dominance rank and age, (3) patterns of youngest ascendency of female dominance rank in vervets, and (4) female philopatry.
 France 2024-04-19 18:38:19 2027-04-19 Natural Sciences Non-Clinical Trial Degree Award
Rhona Mijumbi M
ID: UNCST-2023-R006843
 Regional Hub for Knowledge Translation and Evidence-Informed and Equity-Centred Policymaking in Africa
REFNo: SS2454ES

To assess the impact of cross-country co-created evidence products on the policy making process in the individual countries affected by the same policy challenge,To assess the impact of participation in the regional hub on the development and pilot of new strategies for EIDM,To assess the context specific factors that impact success of a regional hub to support peer-to-peer learning and co-creation in EIDM,To assess the different institutions’ readiness to collaborate in a regional hub to foster cross-institutional peer-to-peer learning for EIDM,To study the impact of a regional hub designed to facilitate cross-institutional peer-to-peer learning on innovative strategies aimed at bolstering evidence-to-policy in priority SDGs in Uganda, Tanzania, Ethiopia, and Malawi. The priority SDGs we shall use for this study are reproductive health and clean energy.,
 Uganda 2024-04-19 18:36:13 2027-04-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
Godfrey Ejuu
ID: UNCST-2021-R013978
 PLAYFUL FUTURES: A RANDOMIZED CONTROL TRIAL OF EARLY CHILDHOOD CARE AND EDUCATION TEACHER TRAINING AND MENTORSHIP IN UGANDA
REFNo: SS1634ES

Overall aim and outcome
The overall goal of the project is “Children improve literacy, numeracy skills and develop socio emotional skills through Learning through Play.
Main research question
To what extent does the ECCE intervention improve quality and sustained learning through play and holistic development among children 3-6 years in centre based learning environments?

Specific research questions
Aim one: To improve quality of the ECCE learning environment for children three-to-six years old
Research questions:
• What is the effect of the LtP intervention on teaching practices, learning environment and development of holistic skills of children three-to-six years from ECCE centers? Is there a difference in outcomes between boys and girls?
Aim two: To improve educators’ instructional practice and implement Learning through Play activities
Research questions:
• What is the effect of LtP mentorship on pedagogical skills in ECCE classrooms? Does this differ by sex of educators?
• What is the effect of the Playful Futures LtP intervention package on pedagogical skills in ECCE classrooms?
Aim three: Coordinating Centre Tutors (CCTs) provide useful, recurrent and effective guidance to educators on LtP
Research questions:
• To what extent does Playful Futures intervention encourage effective and regular mentorship to ECCE educators in support of LtP?
Aim four: Key stakeholders have improved knowledge, attitudes and practices, and abilities to introduce and promote learning through play, including educators, parents, government officials, and community leaders
Research questions:

Research questions:
• What is the effect of playful futures intervention in improving attitudes and practices of parents and community members regarding LtP?
• How does Playful Futures influence parents’ involvement on play activities at home?

 Uganda 2024-04-19 18:24:07 2027-04-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
ABRAHAM OGWAL
ID: UNCST-2020-R014262
 Thermo-Physical Characterization of Briquettes from Maize cobs and Rice husks in Kole District, Northern Uganda
REFNo: NS457ES

(i). To determine proximate composition of briquette samples produced from blended maize cobs and rice husks.
(ii). To evaluate the efficiency of briquette samples produced from blended maize cobs and rice husks.
(iii). To determine gaseous and black carbon emissions level of briquette samples blended from maize cobs and rice husks.

Uganda 2024-04-19 18:10:37 2027-04-19 Natural Sciences Non-Clinical Trial Degree Award
HENRY KATAMBA STANLEY
ID: UNCST-2024-R004704
 A model to improve the adoption, utilisation and sustainability of digital health initiatives by health workers in Uganda.
REFNo: HS4013ES

The purpose of this study will be to investigate the factors that are barriers to improve performance of electronic health management information systems despite adoption of digital health initiatives in health facilities at Uganda and to develop an integrated support model to improve the adoption and sustainability in the utilisation of digital health initiatives and to strengthen performance of electronic health management information systems by health workers in health facilities at Uganda. ,
 Uganda 2024-04-18 13:34:22 2027-04-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Baker  Lukwago
ID:
Optimizing Journey Mapping Techniques: Innovating Methods to Better Understand Pregnancy Journeys for Women Living in Uganda Version 1.2 February 2024
REFNo: HS4024ES

 Objective 2.b: Document women’s experience (satisfaction/dissatisfaction) with digital engagement touchpoints along the pregnancy care-seeking decision pathway, noting differences between urban and rural settings. , Objective 2.a: Determine the potential of remote data collection to capture key pregnancy care-seeking decisions, (attendance of ANC, referral for conditions/ complications, and childbirth experience) including barriers, facilitators and influencers at decision-making point, noting differences between urban and rural settings; gather data on health expenditure at each pregnancy care-seeking pathway point; and capturing quality of maternal care and client experience data,Phase 2- Objective 1: Investigate how remote engagement mechanisms can be used to collect consumer insights more frequently (relative to traditional journey mapping), Objective 1.c: Explore women’s preferences for future digital engagement touchpoints along the pregnancy care-seeking and primary care decision pathway, noting differences between urban and rural settings., Objective 1.b: Describe the quality of maternal care and client experience, disaggregated by urban and rural settings., Objective 1.a: Describe key pregnancy care-seeking decisions, (attendance of ANC, referral for conditions and complications, childbirth experience, follow-up health visits in the post-partum period) including barriers, facilitators, and influencers at decision-making points, noting differences between urban and rural settings and previous pregnancy care experience. ,Phase 1-Objective 1: Use traditional journey mapping techniques to describe the pregnancy care-seeking pathway of women who gave birth in urban and rural settings of Uganda ,
 Uganda 2024-04-18 13:27:52 2027-04-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
 Evaluation for Maverick Next Project on Male Engagement in Contraceptive Use in Uganda: Wakiso District
REFNo: SS2511ES

3. To understand couple practices and perceptions about couple communication on contraception and family size,2. To monitor perception and practices of men towards modern contraception and partner support to access these services.,1. To understand Knowledge and attitude towards modern contraceptives among men in the pilot areas.,
 Uganda 2024-04-18 13:21:59 2027-04-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
EVYLINE ISINGOMA BARUGAHARA
ID: UNCST-2024-R005434
 EFFICACY OF PERSEA AMERICANA AND HIBISCUS SABDARIFFA CALYX, SEEDS AND LEAVES IN MANAGEMENT OF NUTRITIONAL ANAEMIA USING A MOUSE MODEL.
REFNo: HS3779ES

1. To analyse the nutrient composition of Persea Americana leaves and seeds and Hibiscus Sabdariffa leaves and calyx.
2. To determine the bioavailability of iron in Persea Americana leaves and seeds and Hibiscus sabdariffa leaves and calyx.
3. To assess the phytochemical compounds in Persea Americana leaves and seeds and Hibiscus Sabdariffa leaves and calyx.
4. To assess the impact of feeding on Persea Americana leaves and seeds and Hibiscus Sabdariffa leaves and calyx on the haemoglobin, transferrin saturation and serum ferritin levels using a mouse model.
 Uganda 2024-04-18 13:12:46 2027-04-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CHRISTINE  KARUNGI
ID:
Barriers and facilitators to uptake and utilization of the Mental Health Gap Action Programme Intervention Guide (mhGAP-IG) for dementia assessment and management by non-specialist healthcare providers in rural southwestern Uganda: A case study of Kabale District
REFNo: HS3949ES

1. To characterize the barriers and facilitators to utilization of the mhGAP-IG 2.0 for dementia assessment and management by non-specialist healthcare providers in Kabale district 2. To pilot test and evaluate the feasibility of implementing the mhGAP-IG 2.0 for dementia assessment and management by non-specialist healthcare providers in Kabale district 3. To co-design a culturally tailored implementation strategy to enhance adoption of the mhGAP-IG 2.0 for dementia assessment and management by non-specialist healthcare providers in Kabale district
Uganda 2024-04-18 13:07:40 2027-04-18 Medical and Health Sciences Non-Clinical Trial Degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."

NRIMS