Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Silver Bahendeka Karaireho
ID: UNCST-2019-R000876
 Effectiveness of Integrating Non-Communicable Disease Services in Primary Care of Rural Districts in Uganda
REFNo: HS3820ES

5. To formulate a potential framework of NCD integration at PHC in Uganda.,4. To determine the burden of NCDs among patients presenting at PHC in the three adjacent districts.,3. To assess the level and determinants of hypertension control achieved by patients with systemic hypertension after intervention.,2. To assess the level and determinants of metabolic control achieved in patients with diabetes after intervention.,1. To ascertain extent and effect of integration of NCDs at PHC achieved by the WDF19-1721 project. The WDF19-1721 project aimed to optimize care of NCDs through integrating delivery of NCDs services at outpatient clinics in PHC.,To evaluate the effectiveness of an NCD health service delivery framework (WDF19-1721 Project) for integrated management of NCDs in Primary Health Care in three adjacent districts of Isingiro, Ntungamo and Sheema located in Western Uganda.,
 Uganda 2024-02-26 13:01:49 2027-02-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
EDGAR GUMA INNOCENT
ID:
Past-year violence exposure and its association with antiretroviral non-adherence among HIV-positive adolescents in Uganda.
REFNo: HS3831ES

To determine the prevalence of violence exposure and its association with antiretroviral non-adherence among HIV positive adolescents attending the Mildmay Uganda Hospital child and adolescent clinic. , To determine the association between exposure to violence and antiretroviral non-adherence among HIV positive adolescents attending the Mildmay Uganda Hospital child and adolescent clinic.,2. To estimate the prevalence of antiretroviral non-adherence among HIV positive adolescents who experience Physical, sexual and emotional violence attending the Mildmay Uganda Hospital child and adolescent clinic. ,1. To estimate the prevalence of violence exposure among HIV positive adolescents attending the Mildmay Uganda Hospital child and adolescent clinic. ,
 Uganda 2024-02-23 12:34:51 2027-02-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SHIRAH ZIRABAMUZALE MANSARAY
ID:
Sustainable, Responsible and Inclusive Innovation for Mental Health (SRII4MH): How interactions between the built environment, space and mental health policy influence mental health service delivery in the United Kingdom and Uganda.
REFNo: HS2816ES

To examine how mental health policy, the built environment including architecture, infrastructure and space can be re-engineered to ensure innovative, sustainable and efficient mental health service delivery in the United Kingdom and Uganda.,To examine how the debate on patient-centric/ user-driven innovation has influenced mental health policy and built environment considerations, including architecture and infrastructure considerations in Uganda and UK.,To identify the learning flows regarding the SRII4MH between the global North (UK) and global South (Uganda).,To identify the factors and actors that shape decision making for mental health services in Uganda.,
 UK 2024-02-23 11:46:27 2027-02-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Francis Mutebi
ID: UNCST-2023-R007422
 TUNGIASIS IN EAST-AFRICA – AN INTERDISCIPLINARY APPROACH TO UNDERSTAND THE INTERACTIONS BETWEEN PARASITE AND HOSTS – PROJECT PHASE II PROJECT
REFNo: NS721ES

1.3. To establish the behavioral determinants for the heterogeneous distribution of tungiasis in space and time,1.2.To establish environmental factors which influence the distribution of off host stages in the dry and wet seasons,1. To establish the occurrence patterns of tungiasis among humans in the dry and wet seasons,To improve on the understanding of the ecology of tungiasis, and the developmental biology of Tunga penetrans ,
 Uganda 2024-02-14 12:52:02 2027-02-14 Natural Sciences Non-Clinical Trial Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
 EFFECTIVENESS OF FOOD VOUCHERS & BEHAVIOURAL CHANGE COMMUNICATION INITIATIVES ON THE DIETARY DIVERSITY OF CHILDREN IN AMUDAT DISTRICT, UGANDA
REFNo: HS3748ES

To explore the opportunities and challenges for the sustainability of the intervention in Amudat district.,To establish the determinants of the dietary diversity of children aged 6-23 months in Amudat district.,To assess the association between the intervention and change in dietary diversity of children aged 6-23 months in Amudat district.,To determine the dietary diversity of children aged 6-23 months in Amudat district before and after the intervention.,To evaluate the effectiveness of the food voucher programme combined with a BCC package intervention in improving the dietary diversity of children aged 6-23 months in Amudat district.,
 Uganda 2024-02-13 18:11:51 2027-02-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PAUL TURYAHEEBWA
ID:
“Tax Compliance and Revenue Collection Performance in Selected Commercial Enterprises of Greater Mbarara”
REFNo: SS2287ES

3. To explore the effectiveness of self-assessment system and tax compliance on revenue collection performance in the districts of greater Mbarara,4. To examine challenges that hinder tax compliance and revenue collection performance and advance strategies that will enhance revenue collection performance in commercial enterprises of greater Mbarara,3. To explore the effectiveness of self-assessment system and tax compliance on revenue collection performance in the districts of greater Mbarara.,2. To examine the impact of tax compliance by tax reforms on revenue collection performance among commercial enterprises in the districts of greater Mbarara,1. To analyze the levels of tax compliance on revenue collection performance in commercial enterprises in the districts of greater Mbarara.,The main objective of the study is to examine the effectiveness of tax administration and how it affects revenue collection performance among commercial enterprises in greater Mbarara South Western Uganda,
 Uganda 2024-02-13 18:08:21 2027-02-13 Social Science and Humanities Non-Clinical Trial Degree Award
Iga  David
ID:
ENTREPRENEURIAL SUCCESS AMONG MICRO ENTREPRENEURS IN UGANDA
REFNo: SS2258ES

1. To examine the relationship between
psychological capital and entrepreneurial
success.
2. To contrast the relationship between
emotional intelligence and entrepreneurial
success.
3. To relate the relationship between
individual learning behaviors and entrepreneurial success.
4. To explore the relationship between
entrepreneurial bricolage and entrepreneurial success.
5. To test the combined mediation effect of
entrepreneurial bricolage in the
relationship between psychological
capital, emotional intelligence, individual
learning behaviors and entrepreneurial
success.

 Uganda 2024-02-13 18:05:55 2027-02-13 Social Science and Humanities Non-Clinical Trial Degree Award
Derrick Semugenze
ID: UNCST-2023-R007934
 Association of human cytomegalovirus (HCMV) and other viral exposure with susceptibility and progression to tuberculosis disease
REFNo: HS3255ES

Association of HCMV and other viral infections with tuberculosis progression among household and close contacts to tb index cases,Association of human cytomegalovirus (HCMV) exposure with tuberculosis susceptibility in TB presumptive children from Uganda,Association of human cytomegalovirus (HCMV) exposure with tuberculosis susceptibility in TB presumptive adults from Uganda,Association of human cytomegalovirus (HCMV) exposure with tuberculosis susceptibility in TB presumptive adults from South Africa,Association HCMV and other viral infections with susceptibility and progression to tuberculosis disease,
 Uganda 2024-02-13 18:03:22 2027-02-13 Medical and Health Sciences Non-Clinical Trial Degree Award
Tobby Agwe Michael
ID:
Production and Cleansing of Biogas from Bio-degradable Municipal Solid Waste – A Way of Resource Recovery
REFNo: SIR276ES

• To Design and fabricate the system components of the biogas production plant.
• To prepare the organic fraction of the Municipal Solid Wastes.
• To anaerobically digest the Shredded Biodegradable Municipal Solid wastes.
• To cleanse the biogas.

 Uganda 2024-02-13 17:57:42 2027-02-13 Engineering and Technology Non-Clinical Trial Non-degree Award
Alain Favina
ID:
Preparedness of private health workers in Mbarara City about identifying and managing Ebola outbreaks
REFNo: HS3424ES

To determine the relationship between the wellbeing of private health workers and their preparedness towards the Ebola outbreak in Mbarara city,To determine the knowledge, attitude, and practice towards the Ebola outbreak by health workers in private clinics in Mbarara city.,To determine the level of preparedness for the Ebola outbreak by health workers in private clinics in Mbarara City,
 Burundi 2024-02-13 17:56:53 2027-02-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Betty Mwesigwa
ID: UNCST-2020-R014667
 Sabin 003: A Phase 2, Randomized, Double-blind, Placebo-Controlled Trial to Evaluate Safety, Tolerability, and Immune Responses of an Investigational Monovalent Chimpanzee Adenoviral-Vectored Sudan Ebolavirus Vaccine in Healthy Adults
REFNo: HS3628ES

To evaluate the safety and tolerability of cAd3-EBO S vaccine
 Uganda 2024-02-13 17:35:43 2027-02-13 Medical and Health Sciences Clinical Trial Non-degree Award
Friday Christopher
ID: UNCST-2023-R007260
 SUSTAINABLE LAND MANAGEMENT PRACTICES AND ENVIRONMENTAL PROTECTION IN KABALE DISTRICT, UGANDA
REFNo: SS2370ES

i. To examine the effect of agroforestry on environmental protection in Kabale district, Uganda. ii. To determine the influence of crop rotation on environmental protection in Kabale district, Uganda. iii. To assess the effect of trenches and check dams on environmental protection in Kabale district, Uganda. iv. To establish the influence of mulching on environmental protection in Kabale district, Uganda. v. To evaluate the effectiveness of government policies in promoting environmental protection in Kabale district, Uganda.
Uganda 2024-02-09 23:38:35 2027-02-09 Social Science and Humanities Non-Clinical Trial Degree Award
Josephine Nayiga
ID: UNCST-2023-R005839
 Addressing bioethical challenges in HIV research to inform the development of a training program at Makerere University
REFNo: HS3771ES

3. Identify the preferences of trainees regarding future training in bioethics and ascertain their perceived knowledge gaps related to research bioethics,2. Investigate the perspectives of senior investigators at IDI and faculty members at Makerere University based on their experiences, focusing on the ethical dilemmas encountered by trainees engaged in HIV research,1. Evaluate the existing level of awareness and knowledge concerning bioethical challenges in HIV research among current and former trainees at IDI and the School of Medicine, Makerere University,To understand the training needs in research bioethics for trainees in the area of HIV and co-infections, in order to inform the development of a training program at Makerere University,
 Uganda 2024-02-09 23:36:15 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David  Ejalu Livingstone
ID:
ART Adherence among HIV-positive virally unsuppressed adolescents and young people: feasibility, acceptability, and effectiveness of a community-based implementation strategy to optimise compliance with intensive adherence counselling in East-Central Uganda.
REFNo: HS3807ES

1. To determine the level of compliance to IAC and the associated factors among virally unsuppressed Adolescents and Young People living with HIV in East Central Uganda.
2. To explore individual and system-level barriers to and facilitators of compliance to intensive adherence counselling protocol for enhancing ART adherence among unsuppressed Adolescents and Young People living with HIV in East-central Uganda.
3. To design a multifaceted theory-informed community-based IAC Implementation Strategy to optimize adherence for enhancing VLS among unsuppressed AYP in East-central Uganda.
4. To Evaluate the feasibility, acceptability, and effectiveness of a multifaceted theory-informed community-based IAC Implementation Strategy to optimize adherence among unsuppressed AYP in East-central Uganda.

 Uganda 2024-02-09 23:35:00 2027-02-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Peter Elyanu James
ID: UNCST-2021-R013210
 Closing TB Gaps using patient-centered approaches to improve TB Screening, Diagnosis and Prevention among people living with HIV
REFNo: HS3664ES

To assess the performance of novel TB screening algorithms among children,
adolescents, and adults living with HIV and presenting for routine care across a network
of family centered HIV clinics in Uganda and other four sub-Saharan African countries as
compared to the current WHO recommended symptom-based screening strategy.
To compare new diagnostic strategies leveraging the evaluation of multiple specimens
(stool and oral swab Xpert Ultra, early morning urine LF-LAM, point-of-care ultrasound
(POCUS), and a design locked Xpert Host Response Test against a reference standard
(Xpert Ultra on spot and early morning respiratory specimens) to improve diagnostic yield.
To compare the proportion of PLHIV who initiate and complete TPT with 3HP or 6H within
the context of a patient centered differentiated service delivery model allowing selection
of TPT regimen and randomly allocating enhanced adherence support versus the
standard of care for TPT and adherence support.
To evaluate the cost-effectiveness of screening and diagnostic strategies as well as
comparative TPT regimens for the prevention of TB disease among children, adolescents
and adults living with HIV
 Uganda 2024-02-09 23:32:58 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josephine Birungi
ID: UNCST-2023-R005605
 A Family centred approach to enhance lifestyle change and behavioural modification for prevention of cardiovascular diseases among adolescents and their families in Uganda (FaCe-D) study
REFNo: HS3682ES

Main Objective
1. 1. We aim to explore the knowledge on cardiovascular health including CVD risk, perceptions and attitudes of participants, providers and other stakeholders towards the ihealth-T2D family-centered approach (FCA) as an intervention, obtain their input in the modification and design of the intervention to make it appropriate for Ugandan context
Specific Objectives
1. To explore the knowledge on cardiovascular health, perceptions, preferences and recommendations from potential participants on the proposed family-centered approach as an intervention for reducing and controlling common CVD risk factors among adolescents and their families.
2. To identify potential facilitators and barriers to adapting and implementing the FCA intervention in Uganda.
3. To use the data generated to design implementation strategies to promote the delivery, and uptake of the adapted FCA
 Uganda 2024-02-09 23:29:31 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nsobya  Samuel
ID: UNCST-2021-R012265
 Characterizing artemisinin resistance in severe malaria (CHARISMA): SMAART sub-study in Uganda
REFNo: HS3161ES

1. To characterize and compare the ex vivo drug susceptibilities of P. falciparum isolates from patients with and without severe malaria.
2. To characterize and compare genomic features of P. falciparum isolates infecting patients with and without severe malaria.
3. To assess whether presence of artemisinin partial resistance is associated with poor clinical outcomes in severe malaria patients.
4. To assess whether prior receipt of antimalarials is associated with artemisinin partial resistance in severe malaria patients

 Uganda 2024-02-09 23:26:22 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Assessment of Feasibility, Acceptability and Effectiveness of Training Village Health teams On Household Air Pollution Using Teach BOX
REFNo: HS3723ES

1. To assess the feasibility and acceptability of training Village Health Teams on Household Air Pollution using TeachBox in Jinja district Uganda.
2. To assess the effectiveness of training Village Health Teams on Household Air Pollution using TeachBox in Jinja district Uganda
 Uganda 2024-02-09 23:25:22 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Olupot-Olupot Olupot
ID: UNCST-2020-R014798
 DEVELOPMENT OF GEOSPATIO-TEMPORAL SURVEILLANCE AND CHARACTERISATION OF MALARIA IN THE CHANGING CLIMATIC CONDITIONS IN EASTERN UGANDA STUDY (GTS-MACS)
REFNo: HS3725ES

To determine the day three-parasite clearance rates of AL in children treated for malaria in Eastern and Northeastern Uganda. ,To determine whether there are any antimalarial drug resistance markers in Eastern and Northeastern Uganda. ,To describe geospatial-temporal patterns, determinants, and distribution of malaria with temperature, rainfall, and humidity patterns. ,Through geospatial-temporal surveillance, molecular studies and malaria parasite clearance rates, we shall characterise the overall epidemiology of malaria, any emergence of drug resistance and tolerance to the current antimalarials, respectively, in the era of changing climatic conditions in Eastern and Northeastern Uganda.,
 Uganda 2024-02-07 15:13:15 2027-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tonny Muzaale
ID: UNCST-2023-R006443
 Tracer Study of Graduates with Disabilities: A Case of 2010-2020 PLE Candidates
REFNo: SS2196ES

iii. To establish the views of graduates with disability on the relevance of training, skills and competences for the type of work they are doing and corresponding gaps to be filled in future. ,ii. To find out whether the graduates of 2010 PLE and the proceeding years are gainfully employed indicating the location/organizations. ,i. To examine the retrospective views of the students with disabilities based on their career experiences ,
 Uganda 2024-02-06 16:52:25 2027-02-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
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