Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
MIRIAM NAKALEMBE
ID: UNCST-2019-R000824
 Designing and Piloting of a Mobile-based Transport Technology linking Mothers to Health Facilities to Reduce Maternal and New-born Deaths in Uganda during the COVID-19 Pandemic.
REFNo: HS1148ES

1. To identify the existing automated maternal services apps and assess the extent to which they provide near real-time information and communication between mothers and the transporters at community level.
2. To develop a mobile-based transport technology that improves two-way communication between mothers and the transporters at community levels
3. To pilot the mobile-based transport technology for its usability and acceptability

 Uganda 2021-02-10 2024-02-10 Medical and Health Sciences Non-degree Award
Anthony Nuwa
ID:
Evaluating the feasibility, acceptability and protective efficacy of seasonal malaria chemoprevention in two districts in Karamoja, Uganda
REFNo: HS1182ES

Objective 1: To document the adaptation of SMC in Karamoja region in Uganda
Objective 2: To Assess the process of implementing SMC in Uganda, with regards to coverage and quality of implementation
Objective 3: To assess the acceptability of SMC among policy makers, implementers, and beneficiaries.
Objective 4: To determine the impact of SMC on malaria incidence and prevalence among children under 5 years in the Karamoja region and assess the protective efficacy of SPAQ
Objective 5: To analyse cost of SMC delivery to children 3-59 months in Karamoja region
Objective 6: Monitor the safety of sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ) when used in SMC among children 3-59 months in Karamoja region.

 Uganda 2021-02-10 2024-02-10 Medical and Health Sciences Non-degree Award
Noah Kiwanuka
ID: UNCST-2021-R010125
 Capturing spatial patterns of new M. tuberculosis infection in Kampala, Uganda
REFNo: HS1230ES

To map the geo-spatial incidence of Mtb infections in a prospective community cohort study of HIV+ and HIV- adults in Kampala Uganda. GPS tracking technology will be used to trace and map subjects to locate areas of high Mtb transmission, or hotspots. Study participants without tuberculous infection will be followed for IGRA/TST conversion for up to 2 years with serial plasma samples taken quarterly.
To determine and validate whether a defined plasma signature found in other studies can identify recent Mtb infection in persons who developed LTBI. Using a paired analysis, we will evaluate baseline and follow-up samples within individuals to determine whether changes associated with new Mtb infection in the community can be detected in plasma with published and newly developed biomarkers. Using a nested case control design, we will compare incident infections with randomly selected controls from the cohort who did not convert

 Uganda 2021-02-10 2024-02-10 Medical and Health Sciences Non-degree Award
Daphine Namara Arinaitwe Namara
ID:
The Risk of Diabetes and pre-Diabetes associated with use of Dolutegravir based Antiretroviral Therapy among adult persons living with HIV: A Case-control study at Mulago ISS clinic, Kampala, Uganda
REFNo: HS1077ES

Primary objective: To determine the risk of DM and pre-DM associated with the use of DTG-based ART among adult PLHIV at Mulago ISS Clinic.
Secondary objective; To determine other risk factors for DM and pre-DM among PLHIV adult PLHIV at Mulago ISS Clinic.

 Uganda 2021-02-09 2024-02-09 Medical and Health Sciences Non-degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
 A BASELINE ASSESMENT FOR THE ADVANCING SEXUAL REPRODUCTIVE HEALTH AND RIGHTS (ANSWER) PROGRAM IN THE WEST NILE AND ACHOLI SUBREGIONS IN UGANDA
REFNo: HS1079ES

General objective

To analyse the situation of sexual and reproductive health and rights (SRHR) aspects as well as GBV in the intervention districts of UNFPA’s programme targeting to advance SRHR in the Acholi and West Nile sub regions in Uganda, in order to generate scientific evidence that will inform evidence based planning, implementation and form a basis for monitoring and evaluation of the program interventions.

Specific objectives

1.To conduct Health facility assessment at targeted health facilities in West-Nile and Acholi sub regions in regards to offering quality equitable SRHR services (FP/Maternal health/Post abortion Care, HIV testing and Post GBV) that is responsive to the needs of women, girls, boys and men, refugees, and people with disabilities

2.To undertake an assessment of SRHR Knowledge, Attitudes and Practices (KAP) of adolescents and youth in school including refugees and people with disabilities from a sample of 1,800 targeted schools (primary & secondary) in the study districts on GBV and SRHR.

3.To conduct an assessment of SRHR Knowledge, Attitudes and Practices (KAP) of adolescents and youth out of school including refugees and people with disabilities in the study districts on GBV and SRHR.

4.To conduct a budget and expenditure analysis of key sectors at national level and the district local governments focusing on implementation of and accountability towards the demographic dividend priorities.
 Uganda 2021-02-09 2024-02-09 Medical and Health Sciences Non-degree Award
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