Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Sarah Lofgren
ID: UNCST-2019-R001647
 The Growth Study- Group Therapy In HIV For Depression In Uganda
REFNo: HS493ES

Determine if depression, which persists after depression treatment at 26 weeks, is associated with increased innate inflammation in a prospective cohort of HIV-infected Ugandans receiving SSRIs in which group psychotherapy is initiated.
 USA 2019-12-09 2022-12-09 Medical and Health Sciences Non-degree Award
David Lawrence S
ID:
THE LIVED EXPERIENCE OF PARTICIPANTS IN AN AFRICAN RANDOMISED TRIAL (LEOPARD)
REFNo: SS386ES

AIM: To document the AMBITION participant experience in order to build an understanding of how to improve trial delivery for future participants in the trial. OBJECTIVES From the perspective of the participant: 1. To build an understanding of the factors that enhance or diminish a clinical trial experience. From the perspective of the next-of-kin of a participant: 2. To build an understanding of the factors that enhance or diminish a clinical trial experience. From the perspective of the researcher: 3. To build an understanding of the factors that are perceived to enhance or diminish a trial participant’s experience of a clinical trial. 4. To compare the individual researcher’s experience of the conceptualisation, development, initiation and implementation of a multi-centred clinical trial in Africa.
 UK 2019-12-09 2022-12-09 Social Science and Humanities Degree Award
SIMON BYONANUWE
ID:
“Prevalence, bacterial pathogens and factors associated with premature rupture of membranes at Kampala International University Teaching Hospital”.
REFNo: HS503ES

Main objective: To determine the prevalence, bacterial pathogens and factors associated with premature rupture of membranes at Kampala International University Teaching Hospital.

Specific objectives:
1. To determine the prevalence of premature rupture of membranes at Kampala International University Teaching Hospital.
2. To determine the obstetric and gynaecologic factors associated with premature rupture of membranes at Kampala International University Teaching Hospital.
3. To identify bacterial pathogens commonly associated with premature rupture of membranes at Kampala International University Teaching Hospital.
4. To assess antibacterial susceptibility patterns of the isolated bacterial pathogens.


 Uganda 2019-12-09 2022-12-09 Medical and Health Sciences Degree Award
PETER SPENCER SIMNER
ID:
Etiology of Nodding Syndrome: an Epileptic Disorder of East African Children
REFNo: HS410ES

Increase understanding of the role of environmental exposures, notably to specific neurotropic viruses, as risk factors for Nodding syndrome.
 USA 2019-12-04 2022-12-04 Medical and Health Sciences Non-degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
 PERFORMANCE OF ALTERNATIVE MEASURES OF RESPONSE TO THERAPY DURING THE INITIAL 12 WEEKS OF MDR-TB TREATMENT
REFNo: HS471ES

1. To examine the correlations of FDA smear microscopy, PMA-Xpert Ct value &16s rRNA (MBLA) with MGIT-TTP as a reference standard.
2. To evaluate the ability of FDA smear microscopy, PMA-Xpert Ct value, MBLA in predicting 12-weeks MGIT culture conversion (outcome).
3. To evaluate the influence of patient clinical characteristics, baseline resistance profiles, adherence and HIV-status to the performance of the alternative measures of response.

 Uganda 2019-12-04 2022-12-04 Medical and Health Sciences Degree Award
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