Abner Tagoola
ID: UNCST-2021-R013446
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Saving young lives: Triage and management of sepsis in children using the point-of care Paediatric Rapid Sepsis Trigger (PRST) tool
REFNo: HS528ES
The purpose of this study is to develop and implement a digital trigger tool and electronic dashboard to guide frontline health workers in triaging children at facilities in LMICs with severe infection/suspected sepsis. This is with the goal of reducing time to diagnosis and treatment of critically ill children and ultimately reducing preventable child deaths from sepsis secondary to infectious disease.
Specifically, the research seeks to develop a prediction model and to perform clinical validation of a digital trigger tool to guide triage and treatment of children at health facilities in LMICs with severe infections/suspected sepsis.
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Uganda |
2020-02-07 |
2023-02-07 |
Medical and Health Sciences |
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Non-degree Award |
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Menno Veen Niels Eduard
ID:
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VULNERABILITY-RESILIENCE OF POTATO AND RICE FARMERS IN UGANDA TO SHOCKS: AN IMPACT ASSESSMENT OF THE INTERNATIONAL FERTILIZER DEVELOPMENT CENTERS (IFDC) REACH-UGANDA
Project
REFNo: SS413ES
The objective of this study is threefold. First, to understand what are the shocks that rice and potato growing households in South-West and East Uganda are facing and what coping mechanisms households they use prior to and in response to shocks. Second, to quantify the vulnerability of households. Third, to measure the impact of the REACH-UGANDA project on households’ effectiveness of currently used coping mechanisms on well-being and the likelihood to fall into poverty.
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Netherlands |
2020-02-07 |
2023-02-07 |
Social Science and Humanities |
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Degree Award |
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Johanna Meinecke
ID:
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Consumer acceptance of novel healthy fruit and vegetable products in East Africa
REFNo: SS418ES
Factors influencing consumers’ perception of processed fruits and vegetables
(1) Examine sensory characteristics of jackfruit juice and cowpea leaf porridge by rural and urban consumers
(2) Elicit consumers’ willingness to pay for jackfruit juice and cowpea leaf porridge
(3) Relate consumers’ dietary and purchasing behaviour to acceptance of processed fruits and vegetables
(4) Analyse if information on products nutritional value, convenience and seasonality can enhance consumers acceptance
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Germany |
2020-02-07 |
2023-02-07 |
Social Science and Humanities |
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Degree Award |
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Mercy Muwema
ID:
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ASSESSMENT OF THE QUALITY OF PERINATAL CARE, AND DEVELOPMENT OF AN IMPROVED QUALITY OF PERINATAL CARE MODEL TO REDUCE PERINATAL DEATHS IN BUNYORO REGION
REFNo: HS483ES
Primary Objectives
1.To describe the health facility and health worker structures in place to support perinatal care at district hospitals in Bunyoro region.
2.To assess the prevalence and factors associated with poor quality of perinatal care at district hospitals in Bunyoro region
3.To assess the association between quality of perinatal care and birth outcomes at district hospitals in Bunyoro region
4.To explore care providers and client’s experiences on quality of perinatal care at district hospitals in Bunyoro region
5.To develop a context-specific quality of perinatal care model for Bunyoro region
Secondary objective
6.To assess the feasibility and acceptability of the context-specific quality of perinatal care model
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Uganda |
2020-02-06 |
2023-02-06 |
Medical and Health Sciences |
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Degree Award |
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Grace Kisitu Paul
ID: UNCST-2024-R004102
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DPART STUDY: DIHYDROARTEMISININ-PIPERAQUINE IN THE CONTEXT OF ANTIRETROVIRAL THERAPY
REFNo: HS486ES
OVERALL AIM: To determine the PK/PD of DP in HIV-infected children in the setting of first-line ART regimens including LPV/r, EFV and potentially the integrase inhibitor dolutegravir (DTG) which may become widely used in older Ugandan children.
Our primary objectives are:
PRIMARY OBJECTIVES:
1) To evaluate and compare the PK exposure and safety of single dose DP in HIV-infected children on LPV/r-based ART to HIV-uninfected children not on ART (Group L1 vs C1)
2) To evaluate and compare the PK exposure and safety of 3-dose DP in HIV-infected children on LPV/r-based ART to HIV-uninfected children not on ART (Group L3 vs C3a)
3) To evaluate and compare the PK exposure of 3-dose DP in HIV-infected children on EFV-based ART and HIV-uninfected children not on ART (Group E3 vs C3a).
4) To evaluate and compare the PK exposure of 3-dose DP in HIV-infected children on DTG-based ART and HIV-uninfected children not on ART (Group D3 vs C3b).
SECONDARY OBJECTIVES:
1) The effects of DP on antiretroviral PK in the above 3-dose arms (EFV, DTG, LPV/r and controls)
2) To evaluate the association of anthropomorphic indicators of malnutrition on PK exposure of DP in HIV-infected and HIV-uninfected children
3) Assess auto-induction of DHA from single dose to 3-dose
4) To assess the prevalence of pharmacogenetic variants in key metabolic enzymes, including UGT1A1, CYP2B6, CYP3A4, and ABCB1, and the impact of these variants on ACT and ART PK.
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Uganda |
2020-02-06 |
2023-02-06 |
Medical and Health Sciences |
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Non-degree Award |
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