Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,902
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Irene Kinera
ID: UNCST-2022-R009689
POST TB LUNG DISEASE AMONG CHILDREN IN UGANDA, A CROSS SECTIONAL STUDY
REFNo: HS3961ES

3. To assess the health-related quality of life of children and caregivers of children who were previously treated for PTB at Mulago National Referral Hospital.,2. To determine the correlation between clinical characteristics and lung function among children previously treated for PTB at Mulago National Referral Hospital.,1. To describe the clinical characteristics of PTLD among children previously treated for PTB at Mulago National Referral Hospital.,To describe the clinical characteristics of PTLD, assess the correlation between the clinical characteristics and lung function and to assess the health-related quality of life of children and caregivers of children who were previously treated for PTB at Mulago National Referral Hospital. ,
Uganda 2024-05-02 12:39:55 2027-05-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Jenny Löfgren
ID: UNCST-2024-R005428
Simulation-based training for mesh inguinal hernia repair under local anaesthesia - a randomized trial
REFNo: HS4058ES

Assess the learning curve of mesh inguinal hernia repair for novice learners and how it is affected by simulation based training prior to supervised surgery on patients.
Sweden 2024-05-02 12:38:06 2027-05-02 Medical and Health Sciences Clinical Trial Degree Award
Daniel Zaake
ID: UNCST-2019-R000923
Infertility in Uganda: The Burden, quality of Life, lived experiences of individuals Diagnosed with infertility and Availability of services for Diagnosis and treatment of infertility.
REFNo: HS3901ES

1. To determine the prevalence and determinants of infertility in Uganda.
2. To evaluate the quality of life among individuals with infertility seeking fertility treatment in Kawempe National Referal Hospital (KNRH) and St Francis Hospital Nsambya(SFHN) in Kampala
3. To explore the lived experiences of couples and individuals diagnosed with infertility at KNRH and SFHN in Kampala
4. To assess the availability of services for diagnosis and treatment of infertility in Uganda.
Uganda 2024-05-02 12:37:00 2027-05-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Robert Waiswa
ID:
The enablers and barriers to remote work for persons with disabilities in Greater Kampala Metropolitan Area, Uganda
REFNo: SS2394ES

To create a deeper understanding of the enablers and barriers to remote work, including impacts on employability, for PWDs in Greater Kampala Metropolitan Area, principally to inform practice and policy in the design of interventions for disability-inclusive employment in Uganda as the country fast-tracks the UN Convention on the Rights of People with Disabilities, Sustainable Development Goal 10, and Vision 2040.,
Uganda 2024-05-02 12:20:40 2027-05-02 Social Science and Humanities Non-Clinical Trial Degree Award
Sylvester Onzivua
ID:
A Postmortem Study to Explore the Pathological Basis of the Nodding Syndrome
REFNo: HS3048ES

(d) To compare the histological features in the various cases of the NS,c) To determine if there is any evidence of brain infection in NS. ,(b) To characterize the abnormal protein (tau) formation in the brain in NS. ,(a) To determine the main cellular processes occurring in the brain in the NS. ,Main Objective In the study postmortem brain samples will be used to explore the pathological basis of the NS. ,
Uganda 2024-05-02 12:17:16 2027-05-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CHARLES BATUME
ID: UNCST-2021-R013411
Insecticidal and repellent properties of essential oils from catnip (Nepeta cataria) against Aedes aegypti, Anopheles gambiae s.s. and culex quinquefasciatus.
REFNo: HS1717ES

To confirm residual activity and application intervals.,To determine the optimum application dosage(s) and the residual activity.,To determine the efficacy of repellent formulations at the selected application rates against the target vector species.,To establish dose–response relations and determine the ED50 and ED95 of the active ingredient for vector repulsion.,To determine effectiveness of catnip (Nepeta cataria) as mosquito repellent for Ae. aegypti, Anopheles gambiae s.s, and Culex quinquefasciatus.,
Uganda 2024-05-02 12:11:13 2027-05-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dominic Bagenda K
ID: UNCST-2021-R013132
Predictors of Menstrual Hygiene Management among Adolescent Girls in a Rural Resource-deprived Setting in Bukedea District, Uganda.
REFNo: SS1065ES

iv. To quantify the effect of parental predictors on MHM practices among adolescent girls in a rural resource-deprived setting in Bukedea District.,iii. To quantify the effect of socioeconomic predictors on MHM practices among adolescent girls in a rural resource-deprived setting in Bukedea District.,ii. To quantify the effect of personal predictors on MHM practices among adolescent girls in a rural resource-deprived setting in Bukedea District.,i. To determine the proportion of adolescents practicing adequate MHM in a rural resource-deprived setting in Bukedea District.,Quantify the effects of personal, socioeconomic and parental predictors on MHM practices among adolescent girls in a rural resource-deprived setting in Bukedea District.,
Uganda 2024-05-02 12:08:52 2027-05-02 Social Science and Humanities Non-Clinical Trial Degree Award
Peter Rukundo Milton
ID: UNCST-2020-R014799
Testing efficacy and therapeutic potential of egg powder in prevention and management of moderate acute malnutrition: an intervention trial in drought-prone Karamoja, Northern Uganda
REFNo: HS2324ES

(i) Test the efficacy of powdered egg in the prevention of MAM and other related forms of malnutrition in children 6-59 months old. (ii) Assess the therapeutic potential of egg-based products in the management of MAM in the context of supplementary feeding.
Uganda 2024-05-02 12:04:25 2027-05-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Violet Korutaro
ID: UNCST-2019-R000618
IMPAACT Early Career Investigator Award entitled, “Breastmilk Biomarkers of Inflammation, Immune Activation, and Human Milk Oligosaccharides (HMOs) in Women with vs. without Vertical Transmission During Breastfeeding
REFNo: HS4086ES

1. Determine the concentrations of total and various composition of human milk oligosaccharides (HMOs) (lacto-N-fucopentaose; lacto-N-neotetraose; lacto-N- tetraose; 2#-fucosyllactose; 3-fucosyllactose; and three #-sialyllactose); Immunoglobulin isotypes and subclasses (IgG1, IgG2b, IgG2c, and IgG3) in breastmilk of WWH at delivery (up to 5-days) and 4-6 weeks postpartum.

2. Assess the associations of HMO composition and immunoglobulin subclasses with breastmilk-associated HIV transmission.


Uganda 2024-04-26 9:53:07 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sylvia Nabukenya
ID: UNCST-2019-R000906
Developing a guide for ethical review of AI-related research proposals involving human participants
REFNo: SS2558ES

I. To identify the gaps and challenges experienced by research ethics committees during review of AI-related health research projects
II. To examine the ethical considerations of health research involving human participants in AI research
III. To develop a guide for the review of AI-related research projects involving human participants.

Uganda 2024-04-26 9:51:55 2027-04-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Richard Sanya Edwin
ID: UNCST-2023-R006836
Pathways to gestational diabetes screening and diagnosis: a pilot study Identifying health system barriers and facilitators to improve care in rural Uganda.
REFNo: HS4077ES

To investigate the availability of diagnostic services, guidelines, human resources, and financing for GDM care in Kagando HDSS,To explore the knowledge, attitudes, and practices of healthcare providers in detecting and managing GDM in Kagando HDSS,To explore experiences of women with current or previous GDM in Kagando HDSS about the diagnosis and management of GDM,To determine, using facility records, the burden of GDM in primary care facilities in the Kagando Health and Demographic Surveillance System (HDSS),The main objective of this study is to identify barriers and facilitators to the diagnosis of GDM in rural Uganda.,
Uganda 2024-04-26 9:47:15 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alexander Kagaha
ID: UNCST-2024-R004967
REIMAGINING MALARIAL INFECTION CONTROL IN TERMS OF PLANETARY HEALTH BOUNDARIES
REFNo: HS4005ES

To examine the performances through which regimes of malaria and malaria control consciousness conceal and privilege specific human and nonhuman elements.,To examine the shifting terrain of consciousness on malaria control and the conditions that underpin their rise. ,To explore and examine human and nonhuman elements constituted by and within consciousness boundaries of malaria and malaria control interventions. ,To investigate the boundaries of consciousness of malaria and malaria control interventions in Uganda. The boundary of consciousness here denotes the dominant forms of collective and institutional consciousness that guides, regulates, informs and mediates malaria control.,
Uganda 2024-04-26 9:45:31 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HENRY MBOWA STANLEY
ID:
SOCIAL MEDIA USAGE AND MARKET PERFORMANCE OF SMALL AND MEDIUM ENTERPRISES IN WAKISO DISTRICT, UGANDA
REFNo: SS2564ES

iv. To develop a model that will guide social media usage in order to improve the market performance of SMEs in the Wakiso district,iii. To investigate the challenges affecting social media usage by SMEs in the Wakiso district,ii. To examine the influence of social media usage on the market performance of SMEs in Wakiso district,i. To explore the various social media platforms used by SMEs in Wakiso district,The general objective of the study will be to establish the extent to which social media usage enhances market performance of SMEs in Wakiso district, Uganda.,
Uganda 2024-04-26 9:44:07 2027-04-26 Social Science and Humanities Non-Clinical Trial Degree Award
Faisal Kiberu
ID:
Investigation Of Burnt Clay Hollow Block Reinforced Concrete Slab Under Seismic Action
REFNo: SIR327ES

Main To evaluate the seismic behavior of reinforced concrete (RC) frame with Burnt Clay Hollow Block (BC-HB) RC slab under simulated seismic action. Specific Objectives i. To determine the mechanical properties of BC-HB and all other materials that are used in BC-HB RC slab. ii. To simulate the behavior of BC-HB RC slab under seismic action. iii. To design and construct an RC frame with an optimized BC-HB RC slab. iv. To determine the performance of the optimized BC-HB RC slab under seismic action.
Uganda 2024-04-26 9:41:58 2027-04-26 Engineering and Technology Non-Clinical Trial Degree Award
Anthony Kiwanuka N/A
ID: UNCST-2023-R005473
MENTAL HEALTH DISORDER MANAGEMENT AND BARRIERS TO ACCESSING ITS SERVICESAMONG THE RELIGIOUS IN UGANDA
REFNo: SS2517ES

iv. To assess the coping mechanisms available for optimizing mental health disorders among the religious persons. ,iii. To analyze the barriers linked to accessing mental health services faced by the religious persons,ii. To describe mental health services and factors related to stigma associated with mental illness among the people of consecrated life.,i. To explore the ways in which mental health disorder management institutes provide access to services to persons of consecrated life. ,This study will seek to explore mental health disorder management and barriers to accessing its services among the religious in Uganda.,
Uganda 2024-04-26 9:41:00 2027-04-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Peter Olds
ID: UNCST-2023-R006240
Feasibility and effectiveness of atrial fibrillation detection methods among high-risk patients in southwestern Uganda
REFNo: HS3976ES

1. Compare FitBit watch with Holter monitor in detecting the burden of atrial fibrillation among high-risk patients at MRRH. We will compare FitBit watches with the gold standard of Holter monitor for detection of atrial fibrillation among high-risk patients at the MRRH outpatient cardiology clinic. We will also calculate the prevalence of atrial fibrillation in our population and build a regression model for risk factors associated with atrial fibrillation.

2. Evaluate the feasibility and acceptability of implementing atrial fibrillation detection devices in Uganda. Embedded within our non-inferiority trial, we will evaluate the feasibility and acceptability of implementing FitBit watches and Holter monitors using implementation metrics. For primary outcome, we will use the Proctor Model to assess key implementation, service, and client outcomes.

USA 2024-04-26 9:37:51 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abel Bizimana
ID:
EFFECTS OF MEMBERSHIP IN SELF-HELP INGOBYI ASSOCIATIONS ON ACCESS TO MATERNAL HEALTH SERVICES IN THE CONTEXT OF ETHNICALLY MARGINALIZED BATWA IN KIGEZI, UGANDA: A MIXED METHOD STUDY
REFNo: HS4132ES

To determine how Ingobyi Associations affect access to maternal health services, To explore organisational and implementation dynamics within Ingobyi Associations, To determine factors that affect access to maternal health care services among the Batwa and other community members in the Kigezi sub-region.,To determine effects of membership in Ingobyi Associations in access to maternal healthcare services among the Batwa and other community members in the Kigezi sub-region, Uganda,
Uganda 2024-04-26 9:33:28 2027-04-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Felix Bongomin
ID: UNCST-2020-R014224
Undiagnosed Pulmonary Aspergillosis as a Fatal Complication of Advanced HIV Disease in Uganda: An Autopsy-Based Study
REFNo: HS3378ES

The second objective is to determine the burden of co-infections of pulmonary aspergillosis with other pulmonary infections, such as tuberculosis, histoplasmosis, cryptococcosis, and pneumocystosis, among patients with advanced HIV disease who died in selected hospitals in Northern Uganda. ,The first objective is to determine the prevalence and pattern of pulmonary aspergillosis among patients with advanced HIV disease who died in selected hospitals in Northern Uganda.,
Uganda 2024-04-26 9:30:27 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Samson Okello
ID: UNCST-2019-R001580
EsophaCap for the Detection of Early Esophageal Carcinoma
REFNo: HS3248ES

Using our POC approach to carry out a diagnostic pilot study of ESCC in Uganda,In order to achieve fully automatic high-speed biomarker assaying, to design a small,light apparatus,In order to achieve a sample-to-answer assay, to implement DNA extraction, bisulfitetreatment, and methylation-specific PCR into a magnetofluidic chip with dried reagents.,Using a sponge-capsule swallowed/tethered collection device, to construct amethylation marker-based strategy to detect ESCC,To evaluate and validate the performance of the combined sponge methylation biomarker strategy in vivo in PRoBE-compliant, among prospective live cohorts od patients with EAC/HGD, ESCC and gastric cancer and controls in Uganda.,
Uganda 2024-04-26 9:27:48 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Okimait
ID: UNCST-2019-R000095
Amref Uganda 2023 - 2030 Strategic Plan Baseline Survey
REFNo: HS3697ES

To set a benchmark for Amref Uganda’s country strategy indicators for the strategic platforms and eight strategic objectives. To carry out a stakeholder analysis of access, utilization, and provision of healthcare services as well as assessing the preparedness of health facilities for public health emergencies in Uganda. To recommend actions to improve the chances of achieving Amref Uganda's 2023-2030 strategy.
Uganda 2024-04-26 9:26:30 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."