Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Annet Namusisi Mary
ID: UNCST-2025-R017592
Evaluation of the Uganda Public Health Bulletin impact
REFNo: HS5978ES

1. Determine the reach of the UPHB among national, district, and international stakeholders 2. Explore how readers perceive the relevance, quality, and usefulness of the UPHB 3. Assess Content Quality Using Standardized Scorecards 4. Analyze trends in digital engagement as measured by email open rates, click-through rates, and website traffic over the past five years 5. Evaluate the impact of the UPHB on public health decision-making within 9 years of existence
Uganda 2025-06-02 17:38:50 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
WALAKIRA FELIX JOSHUA
ID: UNCST-2023-R007993
COMMUNITY PERCEPTIONS ON HERBAL MEDICINES USE IN TREATING UPPER RESPIRATORY INFECTIONS IN KATANGA SLUM, UGANDA; A WAY OF SPARING ANTIBIOTICS.
REFNo: HS5902ES

1. To explore prevailing perceptions and beliefs within the community regarding the efficacy of herbal medicines in treating upper respiratory infections.
2. To explore the perceived barriers and facilitators to the adoption of herbal medicines in treating Upper Respiratory Infections as a means of sparing antibiotics.
3. To determine the proportion of people in Katanga who have suffered from Upper Respiratory Infections.

Uganda 2025-06-02 17:37:03 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Holly Parsons Jane Emily
ID: UNCST-2024-R002678
Case Study: Exploring the Effectiveness of Village Health Teams in Uganda's 12 Refugee-Hosting District
REFNo: SS3874ES

The main objective on this research is to drive the narrative on a successful method of transition from humanitarian-funded to government ownership of health systems for refugees in low- and middle-income countries that depends on responsibility-sharing as part of the Global Compact on Refugees. The specific objective is to explore the effectiveness of Village Health Teams (VHTs) in Uganda's 12 refugee-hosting districts in preventing and treating human malaria by identifying key successes and key challenges of this health system, and then exploring how successes can be proliferated and how challenges can be mitigated.
Canada 2025-06-02 17:20:52 2028-06-02 Social Science and Humanities Non-Clinical Trial Degree Award
Amon Tayebwa
ID: UNCST-2024-R002098
THE ANATOMICAL VARIATIONS AND DISTRIBUTION OF THE HUMAN CORONARY ARTERIES: A CADAVERIC STUDY AT MBARARA REGIONAL REFERRAL HOSPITAL IN SOUTH WESTERN UGANDA.
REFNo: HS6003ES

1.What are the different branching and dominance patterns of the human coronary arteries amongst unclaimed bodies at Mbarara Regional Referral Hospital?
2.What are the different patterns of origin of coronary arteries at the sinotubular junction amongst unclaimed bodies at Mbarara Regional Referral Hospital?
Uganda 2025-06-02 17:17:36 2028-06-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Gloria Naome Aduku
ID: UNCST-2024-R015930
IMPACT OF ANTHROPOGENIC ACTIVITIES (TOURISM) AND PARASITISM ON PHYSIOLOGIAL STRESS IN GORILLAS (Gorilla beringei beringei) IN BWINDI IMPENETRABLE NATIONAL PARK
REFNo: NS971ES

• To evaluate six different Enzyme Immunoassays (EIA) for quantifying fGCMs in mountain gorillas.
• To investigate the effect of bacterial metabolism and environmental factors on the stability of faecal glucocorticoid metabolite (fGCM) concentrations post-defaecation
• To examine variation in parasitic burden and fGCM concentrations of spatially separated mountain gorilla groups.
• To examine parasitic burden and fGCM concentrations of mountain gorillas during high and low tourism activity.
• To identify specific parasitic infections that correlate with elevated fGCM concentrations in mountain gorillas.

Uganda 2025-06-02 17:16:50 2028-06-02 Natural Sciences Non-Clinical Trial Degree Award
AHEEBWA ROGGERS COLLINS
ID: UNCST-2025-R017036
Tax Policies And Financial Performance Of Small & Medium Enterprises (SMEs) in Uganda: A Case Of SMEs in Kabale District
REFNo: SS3844ES

i. To examine the effect of tax compliance costs on the financial performance of small and medium enterprises in Kabale district
ii. To examine the effect of tax incentives on the financial performance of small and medium enterprises in Kabale district.
iii. To examine the effect of tax rates on the financial performance of small scale and medium enterprises in Kabale district.


Uganda 2025-06-02 17:15:52 2028-06-02 Social Science and Humanities Non-Clinical Trial Degree Award
Kamya Moses
ID: UNCST-2020-R014203
A case-control study to assess the effectiveness and safety of the R21/matrix-M malaria vaccine
REFNo: HS6009ES

To assess the Vaccine Effectiveness (VE) of R21/Matrix-M vaccine against severe malaria caused by Plasmodium falciparum.

To assess the Vaccine Effectiveness (VE) of the R21/Matrix-M vaccine against clinical malaria in high-transmission perennial areas caused by Plasmodium falciparum.

To assess if the R21/Matrix-M vaccine recipients are at an increased risk of death (all-cause).
Uganda 2025-06-02 17:04:40 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
PROTOCOL FOR THE PERFORMANCE EVALUATION OF ALINITY M HIV-1 ASSAY USING DRIED BLOOD SPOT SPECIMENS HIV VIRAL LOAD ASSAY FOR WHO PREQUALIFICATION ASSESSMENT
REFNo: HS6061ES

• To assess the Alinity m HIV-1 DBS assay’s agreement with a cobas HIV-1 Quantitative nucleic acid test for use on the cobas 6800/8800 Systems (Roche Diagnostics GmbH) on clinical specimens, including:
o Quantitative assessment of bias, limits of agreement and correlation
o Misclassification above or below the clinical threshold (1000 copies/mL)
• To assess the analytical performance of the Alinity m HIV-1 assay using DBS:
o Precision (repeatability and within-laboratory reproducibility)
o Linear range on the main subtypes
o Limit of detection
o Cross-contamination
• To describe the operational characteristics and ease of use of the Alinity m HIV-1 assay using DBS and its suitability for use in countries with limited infrastructure.

Uganda 2025-05-29 17:20:17 2028-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
STANDARDTM M10 HR-HPV: Evaluation of Clinical Performance and Usability in the hands of untrained users.
REFNo: HS6022ES

Demonstration of usability of the STANDARDTM M10 Hr-HPV assay. ,Demonstration of sample type equivalence for the STANDARDTM M10 Hr-HPV assay: ThinPrep® PreservCyt® Solution (Hologic) vs. BD SurePathTM Collection Vial (Becton, Dickinson and Company),Determination of the relative diagnostic sensitivity and specificity i.e. compared with the Roche Cobas HPV assay (used according to the current standard of care at the study site).,Determination of clinical accuracy i.e. absolute diagnostic sensitivity for CIN2+ and CIN3+ and absolute diagnostic specificity for ≤ CIN1.,To demonstrate the clinical performance of the STANDARDTM M10 Hr-HPV assay when used by healthcare professionals in a laboratory setting or health institution (i.e. intended use setting), the following objectives have been defined.,
Uganda 2025-05-29 17:19:03 2028-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anatoli Mawanda
ID: UNCST-2024-R015927
GENETIC AND MOLECULAR DETERMINANTS OF BREAST CANCER DISPARITY AMONG AFRICAN, AFRICAN AMERICAN AND WHITE POPULATIONS
REFNo: HS6015ES

To study the genetic, molecular, and biological regulators of breast cancer in Ugandan
women and compare them with African American and white women.
Uganda 2025-05-29 17:17:31 2028-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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