Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Riley Derby Nicholas
ID: UNCST-2025-R017680
Impacts of early social life on social and physical development in mountain gorillas
REFNo: NS946ES

Study social and physical change in immature mountain gorillas in Bwindi Impenetrable National Park, in collaboration with Bwindi Gorilla Project, through combining behavioral, hormonal, and non-invasive growth measures
USA 2025-03-25 11:02:11 2028-03-25 Natural Sciences Non-Clinical Trial Non-degree Award
Erika Sininärhi
ID: UNCST-2025-R017295
Physiological correlates of variation in personality traits in the banded mongoose Mungos mungo
REFNo: NS942ES

1) To determine the relationship between social rank, prenatal androgen exposure, and personality. 2) To investigate whether individual differences in facial thermal patterns are connected to personality, behaviour and stress reactivity.
Finland 2025-03-25 11:01:27 2028-03-25 Natural Sciences Non-Clinical Trial Degree Award
David Hayman T. S.
ID: UNCST-2023-R006403
One Health, multiple factors: an interdisciplinary investigation of emerging infectious disease
REFNo: NS924ES

Infectious diseases significantly impact global health, affecting both humans and animals. Zoonotic diseases, which are transmitted between animals and humans, pose particular risks in regions with high human-wildlife interaction. One such region is Uganda, specifically around Bwindi Impenetrable National Park (BINP), where communities live in close proximity to domestic and wild animals.

The objectives of this research are to:

Identify and quantify zoonotic pathogens in fecal samples from various animal species.

Assess pathogen prevalence across different species.

Analyze microbial community structures and antimicrobial resistance genes.
New Zealand 2025-03-25 11:00:19 2028-03-25 Natural Sciences Non-Clinical Trial Non-degree Award
Joan Mutyoba Nankya
ID: UNCST-2021-R010992
Using patient journey mapping approach to understand and improve post-abortion care within routine health care services
REFNo: HS4137ES


General objective

The general objective of this study is to use a journey mapping approach to understand client experiences as they navigate abortion services, and gaps in services, in order to improve PAC service delivery, client experiences and outcomes within the health care system.
Specific objectives

The specific objectives of the journey mapping approach include:

1. To document client experiences at different stages of post-abortion care-seeking.
2. To understand the current service provision processes for clients seeking post-abortion care services and identify gaps and unmet needs in these services.
3. To evaluate comprehensiveness of care and identify interventions to improve care.
4. To compare patient experiences with established standards of care

The specific objectives of the survey include:
1. To characterize the type and range of contraceptive and abortion-care services available for women who seek care at health facilities.
2. To determine whether women, including young women, receive comprehensive counseling on choices related to manual vacuum aspiration (MVA), medical abortion (MA) and contraception and which factors are related to receipt of such counselling.
3. To determine whether family planning and abortion services are provided with respect and compassion.

Uganda 2025-03-25 10:56:04 2028-03-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Karen Bailey M.
ID: UNCST-2024-R003544
Understanding invisible socio-environmental systems through pesticides across human-wildlife interactions
REFNo: SS3710ES

To model simulations of the interactions within the SES, illustrating the feedback mechanisms between pesticide use, environmental changes, and human-wildlife well-being,To quantify pesticide exposure and associated health outcomes in humans and wildlife, with a focus on spatial and temporal trends,To assess socio-economic and environmental factors influencing farmers\' decisions regarding pesticide use,To investigate the socio-environmental drivers and molecular-level impacts of pesticide use in a tropical forest-agricultural mosaic and develop strategies that balance agricultural productivity with biodiversity conservation among communities around the Kibale National Park ,
USA 2025-03-25 10:53:06 2028-03-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
Integrating management of alcohol use, intimate partner violence, and menopausal transition into HIV care for women living with HIV in Uganda
REFNo: HS5750ES

To explore the unique health challenges faced by women living with HIV in Uganda related to intimate partner violence, menopausal transition, and alcohol use disorder (AUD), focusing on distinct age groups to inform targeted health interventions
Uganda 2025-03-19 13:02:04 2028-03-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abel  Kakuru
ID: UNCST-2022-R009193
Epidemiology of Malaria Infection in Sub-Saharan African Countries
REFNo: HS5638ES

To estimate the site-specific IR of P. falciparum infection by rapid diagnostic test (RDT) testing, overall and by age group (5-11 years, 12-17 years, 18-60 years) during the active detection of infection period.
Uganda 2025-03-19 12:57:39 2028-03-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Noeline Nakasujja
ID: UNCST-2019-R001428
Clonal Hematopoiesis: A Global Perspective on the Impact of CH on Alzheimer’s Disease in Sub-Saharan Africa
REFNo: HS5533ES

Main Objective
1. The aim of this proposed work is to compare the frequency and type of clonal hematopoiesis (CH) mutations in age-matched African American and Ugandan populations. We intend to determine the correlation between specific CH-associated mutations and development of Alzheimer’s Disease in both a Ugandan and African-American population.

Specific Objectives
1. Compare the frequency of CH in an elderly African American versus elderly Ugandan population.
2. Compare the types of CH mutations in an elderly African American versus elderly Ugandan population.
3. Determine the correlation between specific CH-associated mutations and the development of AD in a Ugandan population.
Uganda 2025-03-19 12:53:37 2028-03-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
STEVEN SEBBALE
ID: UNCST-2023-R006063
PARTICIPATION OF FEMALE DOCTORATE HOLDERS IN SCIENCE, TECHNOLOGY AND INNOVATION: AN EXAMINATION ON GENDER EQUITY, INCLUSIVITY AND INTERSECTIONALITY IN UGANDA
REFNo: SS3712ES

a) To examine the demographic and professional characteristics of female doctorate holders in Uganda
b) To assess the intersectional challenges faced by female doctorate holders in Uganda
c) To provide data-driven insights for integrating intersectionality into UNCST’s grants system
Uganda 2025-03-18 13:09:22 2028-03-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Richard Wismayer
ID: UNCST-2019-R000483
The microbiome as an aetiological factors in colorectal carcinoma in Ugandan patients
REFNo: HS5644ES

1. To investigate the frequency of carriage of faecal P. micra in Ugandan CRC patients and controls by 16S rRNA sequencing and PCR and assess its potential as a non- invasive biomarker compared to other bacteria (Study 1).

2. To explore the associations of P.micra and F.nucleatum, the general tumour microbiome, the intra-tumour immune response and the tumour MSI status within the tumour itself. P.micra and F.nucleatum will be determined by PCR, the tumour microbiome by 16S rRNA sequencing and the tumour immune response both pathologically and by the numbers of infiltrating lymphocytes a key prognostic marker. MSI and MSS status will also be identified (Study 2).

3. To analyse the bacterial content of faeces using 16S rRNA sequencing in relation to the clinical features and MSI/MSS status of CRC in Ugandan patients and controls using network analysis in Ugandan patients. To identify bacteria positively and negatively associated with Ugandan bowel cancer carriage (Study 3).

4. To determine the prevalence of cancer related stool toxins, pks, FadA, and ETBF in Ugandan colorectal cancer patients and controls using quantitative PCR assays on faeces (Study 4).

5. To compare the above findings with those of CRC patients and controls from the international microbiome network in Ghana, India, Vietnam, Argentina and England (Study 5).

Malta 2025-03-18 13:03:54 2028-03-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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