Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Elizeus Rutebemberwa
ID: UNCST-2022-R009070
Evaluation and Scale-up Strategy for the Doctor@Distance Programme in Uganda
REFNo: HS955ES

4.3 General objective
To evaluate the Doctor@Distance programme by identifying current benefits and gaps and exploring the path for further development of the programme and potential embedment of the programme in the larger health system.

4.4 Specific objectives
1.To explore what the multi-stakeholder perceptions are on the design and daily practice of the Doctor@Distance programme
2.To analyse the design and current utilisation of the Doctor@Distance programme and identify potential gaps in its coverage (how often is it used, by whom, for which diseases, etc.)
3.To evaluate the current healthcare gaps in the communities in which the community health entrepreneurs of the Doctor@Distance programme are active
4.To explore how the Doctor@Distance programme can be scaled-up to other districts within Uganda
5.To investigate multi-stakeholder perceptions on the possibility of integration of the Doctor@Distance programme in the larger health system in Uganda


Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
Richard Nyeko
ID: UNCST-2021-R012815
Pre-hospital exposure to, and antimicrobial drug resistance patterns among febrile children presenting to St. Mary’s Hospital Lacor, northern Uganda
REFNo: HS1091ES

General objective To determine the prevalence of pre-hospital exposures to antibiotics, common bacteria and their susceptibility to microbial drugs among febrile children presenting to a tertiary health facility in northern Uganda. Specific objectives 1. To determine the prevalence of pre-hospital exposures to antibiotics among febrile children presenting at St Mary’s Hospital Lacor 2. To establish the common bacterial isolates among febrile children presenting at St Mary’s Hospital Lacor 3. To determine the microbial resistance patterns among febrile children presenting at St Mary’s Hospital Lacor
Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
Aidah Nanvuma
ID: UNCST-2024-R015734
EVALUATING THE CAPACITY BUILDING MODEL USED TO NURTURE INDEPENDENT RESEARCH INVESTIGATORS AT THE INFECTIOUS DISEASES INSTITUTE, UGANDA
REFNo: HS1100ES

Objective 1: To describe Capacity Building Unit support activities and scholarly outputs and outcomes since inception. Objective 2: To determine how particular components of the unit scientific and non-scientific support(Inputs) contribute to scholar (past and present) outputs and outcomes since inception. Objective 3: To identify and address areas of improvement in unit support activities through the engagement of current and former stakeholders (beneficiaries and benefactors).
Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
A Study to Validate and Improve an Automated Image Analysis Algorithm to Detect Tuberculosis in Sputum Smear Slides: Version 1.0 dated Nov 2020
REFNo: HS1144ES

1. Validate the platform, and assess efficiency improvements from computerized detection approaches.
a. Perform a slide specimen digitization (400 slides, 98 images/slide, 39,200 images).
b. Classify all images as dark/medium/light based on color histogram data.
c. Assess accuracy vs. manual microscopy, and sensitivity/specificity vs. bacterial culture.
d. Develop a new image analysis algorithm by integrating software applications that include Artificial Intelligence (AI) approaches via Convolutional Neural Networks (CNN).
2. Quantify slide staining quality and variability through the use of novel methods which exploit the color spectra of stained slides.
a. Determine factors which led to poor slide preparation.
b. Test a new quality control method (HistoQC) to standardize clinical slide preparations

Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
THOMSON LAKWO LURONI
ID: UNCST-2023-R007843
Evaluation of the Diagnostic Tests in Areas Hypoendemic for Onchocerciasis –Uganda: a follow-up study.
REFNo: HS1220ES

Objective 1: Evaluate the distribution of anti-OV-16 antibody and other markers of O. volvulus infection in multiple age groups over time in an area of active intervention for onchocerciasis
Objective 2: To determine whether a serologic threshold of 2% that modeling suggested is consistent with interruption of transmission.
Objective 3: Monitor for sero-reversion of OV-16 antibody positivity in a nested cohort of individuals who participated in the previous study.

Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
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