Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Annette Schuh Hildegard
ID: UNCST-2024-R003745
 Evaluation and Transfer of mobile whole slide tissue scanners and liquid biopsies to deliver fast and precise diagnosis for improved outcomes of children and young adults with EBV-driven lymphoma: a joint Tanzanian and Ugandan Paediatric Oncology Network Initiative
REFNo: HS529ES

We have four objectives: to 1. Assess the diagnostic accuracy of liquid biopsy testing 2. Asses the diagnostic accuracy of digital pathology 3. Development of a digital pathology machine learning algorithm 4. Transfer of above novel tests and associated expertise to local laboratories
 UK 2020-04-24 2023-04-24 Medical and Health Sciences Non-degree Award
Peter Nkurunziza Munya
ID:
'Evaluation of The Bio-Rad Geenius HIV-1/2 Confirmatory Assay as Part of Confirmatory and Differentiation of HIV infection at Uganda Virus Research Institute-HIV Reference Laboratory'
REFNo: HS612ES

Primary objective
• To conduct an in-country evaluation of the performance of Geenius™ HIV-1/2 Confirmatory Assay for confirmation of HIV infection using DBS and Plasma specimens, as compared to Murex HIV Ag/Ab Combination and/or Genscreen Ultra HIV Ag/Ab Combo.
Specific objectives
• To determine the sensitivity of Geenius™ HIV-1/2 Confirmatory Assay as compared to Murex HIV Ag/Ab Combination and/or Genscreen Ultra HIV Ag/Ab Combo
• To determine the specificity of the Geenius™ HIV-1/2 Confirmatory Assay as compared to Murex HIV Ag/Ab Combination and/or Genscreen Ultra HIV Ag/Ab Combo
• To determine the positive predictive value and negative predictive value of Geenius™ HIV-1/2 Confirmatory Assay as compared to Murex HIV Ag/Ab Combination and/or Genscreen Ultra HIV Ag/Ab Combo.

 Uganda 2020-04-24 2023-04-24 Medical and Health Sciences Non-degree Award
PROSPER BEHUMBIIZE
ID:
Implementation Research on Education Management Information Systems (EMIS) Data Use Innovations in Uganda
REFNo: SIR33ES

1. To assess the existing management information systems for the Education Sector
2. To understand how innovations including DHIS2 can be used to improve EMIS data quality, management and use at all levels of the education sector
3. To ascertain the best practices that will inform scale up of Dhis2-for Education within and across countries

 Uganda 2020-04-17 2023-04-17 Engineering and Technology Non-degree Award
Peter Olupot-Olupot
ID:
Coronavirus Disease 2019 Open Cohort (COC) Study
REFNo: HS611ES

The specific objectives:
1. Through a cross sectional survey describe risk factors and enlist study participants for the cohort study.
2. To characterize the clinical spectrum of COVID-19.
3. To refine case definitions of COVID-19 using data from different population groups.
4. To explore in detail, the epidemiology of COVID-19.
5. To document outcomes associated with COVID-19 in various age groups, populations and concomitant conditions.
6. To generate data to inform clinical research on COVID-19.
7. To generate population specific data for evidence based public health education as a control measure.
8. Provide a decision tree that has automated feedback that has standard of care including quarantine, call help-line, seek medical attention and avoid spread of the disease.

 Uganda 2020-04-03 2023-04-03 Medical and Health Sciences Non-degree Award
AGNES NAGGIRINYA BWANIKA
ID: UNCST-2019-R001126
 Acceptability, effect and cost of mobile-health on art adherence among youths: a mixed methods sequential study in Kiryandongo
REFNo: HS576ES

General objective: To assess the acceptability, effect and cost of the Call For Life Uganda mHealth tool on ART adherence among youth initiating ART at Kiryandongo Hospital.

Specific objectives:
Objective 1a: To assess barriers, enablers of ART adherence among youth living with HIV in Kiryandongo Hospital at baseline & study end.
Objective 1b: To assess acceptability of mHealth for HIV adherence among youth living with HIV in Kiryandongo Hospital at baseline & study end.
Objective 2: To assess effect of the CFLU mHealth tool on ART adherence among youths initiating ART at 6 and 12 months.
Objective 3: To evaluate the cost of the CFLU mHealth adherence tool in comparison to Standard of Care.

 Uganda 2020-03-28 2023-03-28 Medical and Health Sciences Degree Award
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