Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
John Bosco Ddamulira Mayanja
ID: UNCST-2022-R010819
Burden of Snakebites and Snakebite Envenoming in Uganda: A community survey and Health facility Audit
REFNo: HS566ES

I. Determine the incidence of snakebite envenoming in Uganda
II. Characterize the snakebites and snakebite envenoming in Uganda
III. Describe the snakebite envenoming outcomes
IV. To describe snakes commonly responsible for snake bites in Uganda.
V. Establish the spatial distribution of the common snake species in Uganda
VI. Identify the community practices following snakebite envenoming in Uganda
VII. Assess health facility capacity (human, equipment & supplies) to manage snakebite envenoming

Uganda 2020-06-30 2023-06-30 Medical and Health Sciences Non-degree Award
VICTORIA WALUSANSA ABALIWANO
ID: UNCST-2021-R012155
Exploring the Molecular Spectrum of Colorectal Cancer in Uganda
REFNo: HS667ES

Primary Objective: Estimate the prevalence of BRAF and KRAS mutations, CIMP, and MSI in colorectal tumors in the KCR.
Secondary Objectives:
(1) Describe the demographic and clinical characteristics of colorectal cancer cases in the KCR.
(2) Evaluate associations of demographic and clinical characteristics with the prevalence of BRAF and KRAS mutation, CIMP, and MSI in colorectal cancer cases in the KCR.
(3) Evaluate associations of survival time with tumor molecular phenotypes (BRAF, KRAS, CIMP, MSI) and other participant information.

Uganda 2020-06-30 2023-06-30 Medical and Health Sciences Non-degree Award
Sachin Gathani Gathani
ID:
Effect of Covid-19 lockdown measures on coffee farmers in Central and Western Uganda
REFNo: SS486ES

This study aims to understand the effect of COVID-19 and the consequent lockdown
measures on coffee farming households in the JDE Farm College a program being
implemented by TechnoServe (a non-profit organization). JDE is working in partnership with Technoserve to train coffee farmers on coffee agronomy best practices, helping them improve
the quality and yields of their coffee trees, which in turn will increase their income in the long term. Farmers are enrolled in the training program every 2 years in what is referred to as a
“cohort”. Enrolled farmers come together and form a focal farmer group and a farmer trainer is appointed to run the training sessions. Coffee demo plots are implemented in order to train farmers in real-life conditions. The trainings are conducted every month and attendance is tracked. Laterite is a research, data and advisory firm with offices in Kampala who is partnered with TechnoServe to provide research support for the monitoring and evaluation activities of the TechnoServe Farm College Program.
The main objective of the study is to generate timely data and insights for TechnoServe and coffee industry stakeholders on how coffee farming households that are part of their agronomy training program are affected by COVID-19 crisis and the consequent lockdown measures to address Covid-19. This will be useful for TechnoServe, to inform their programming including targeting interventions to areas that need them most and considering options for redirecting
resources from coffee agronomy to other types of training.
The results from this study will result in monthly briefs (not an academic study) that
demonstrate farmer’ knowledge of COVID-19 and how the lockdown measure may have
affected their farming activities including access to input, farms and markets.
Kenya 2020-06-30 2023-06-30 Social Science and Humanities Non-degree Award
Arthur Kwizera
ID: UNCST-2021-R012928
A multicenter, prospective, randomized, placebo-controlled, open label, stepped wedge clinical trial of respiratory support with continuous positive airway pressure or high-flow oxygen therapy in adults with acute hypoxemic respiratory distress in Uganda.
REFNo: HS523ES

Primary objective
To assess the efficacy of CPAP and HFNC in improving 28-day survival in patients with AHRF.

Secondary objectives
Secondary objectives are to:
- Determine the feasibility, safety, tolerance and comfort of CPAP and HFNC;
- Evaluate the impact of CPAP and HFNC on morbidity, including the need for intubation, ventilator free days, organ dysfunction, and hospital length of stay.


Uganda 2020-06-29 2023-06-29 Medical and Health Sciences Degree Award
Musa Sekikubo
ID: UNCST-2020-R014404
Maternal, Neonatal and Infant Outcomes at Kawempe National Referral Hospital
REFNo: HS623ES

COMPONENT1: Will describe baseline maternal and neonatal outcomes using anonymised data collected using the routine Kawempe electronic medical records (EMR) system. For this, we seek approval to perform a secondary analysis of anonymised data from Kawempe National Referral Hospital and request for a waiver of individual informed consent since the data will be de-identified.
COMPONENT 2: Will collect comprehensive data on pregnancy, neonatal and infant outcomes in a prospective cohort of approximately 4,000 pregnant women enrolled in the first and second trimesters while attending antenatal care at Kawempe Hospital with follow-up of the mother-infant pairs up until around 9 months of age. Written informed consent will be obtained from all mothers, and from the fathers of the babies if they are available.

Uganda 2020-06-27 2023-06-27 Medical and Health Sciences Non-degree Award
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