Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
FADHIL GERIGA
ID: UNCST-2022-R011524
Optimizing Nephroblastoma treatment outcomes in Uganda
REFNo: HS822ES

Primary Objectives:
o To determine the one-year survival of children with pathology confirmed nephroblastoma treated with multidisciplinary, stage-based care in Uganda.
o Assess the factors associated with morbidity and mortality among children with nephroblastoma.

Secondary Objectives:
o Characterize the frequency and spectrum of other malignancies that present similar to Nephroblastoma
o Characterize the social needs and health literacy of nephroblastoma patients and their caregivers at the UCI
o Assess quality measures of a multidisciplinary care, including:
- Treatment timing benchmarks following guidelines developed for UCI
- Adherence to treatment plan and elimination of loss to follow-up
o Assess social needs and provide a patient navigator for families of children with nephroblastoma and reduce the non-clinical barriers to care for children with nephroblastoma

Exploratory Objectives:
o To collect plasma for future studies evaluating circulating tumor DNA as a tool for diagnosis of pediatric kidney cancers and monitoring of patients with nephroblastoma.
o Collect stool specimens for future studies to define baseline factors in the stool microbiome that are associated with neutropenic fevers, sepsis and 12 months survival using combination of sequencing methods and stool ova and parasites evaluation.
Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
EXPLORING CHILDREN’S UNDERSTANDING OF COVID-19 AND ITS PREVENTIVE STRATEGIES IN UGANDA: A CROSS SECTIONAL STUDY AMONG CHILDREN AGED 10-13 YEARS IN HOIMA DISTRICT
REFNo: HS830ES

General objective

To explore children’s understanding of COVID-19 disease and related preventive measures, in order to generate information that will guide the development of evidence-based strategies for strengthening and improving children safety and wellbeing during and after the COVID-19 crisis.

Specific objectives

1.To establish the children’s knowledge of COVID-19 transmission and its preventative measures in Hoima Municipal Council

2.To describe how the COVID-19 preventative measures are understood and practiced by children aged 10 to 13 years in Hoima Municipal Council

3.To explore the enablers for the recommended health measures for the prevention of COVID -19 among children aged 10 to 13 years in Hoima Municipal Council

4.To explore the barriers for the recommended health measures for the prevention of COVID -19 among children aged 10 to 13 years in Hoima Municipal Council

Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
Formative Study to Understand Drivers and Barriers to Uptake of Permanent Methods of Family Planning Among Men and Women in Busoga Sub region
REFNo: HS862ES

The overall objective is to understand the factors that influence women, men and providers in Busoga region during the journey to access PMs to enable PSIU to design interventions.
Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
NAUME MUYANGA
ID:
UNDERSTANDING THE IMPACT OF GENDER BASED VIOLENCE ON HIV/AIDS PREVENTION AND TREATMENT HEALTH SEEKING BEHAVIORS AMONG TRANSWOMEN IN THE GREATER KAMPALA METROPOLITAN AREA, UGANDA.
REFNo: SS557ES

Broad objective:
To understand the impact of gender-based violence on HIV/AIDS prevention and treatment seeking behaviors among the transwomen in the greater Kampala metropolitan area, Specific objectives:
1. To document the lived gender-based violence experiences among the transwomen in the greater Kampala metropolitan area, Uganda.
2. To explore the existing gender-based violence referral pathways used by the transwomen in the greater Kampala metropolitan area, Uganda.
3. To explore the impacts of gender-based violence on HIV/AIDS prevention and treatment seeking behaviors among the transwomen in the greater Kampala metropolitan area, Uganda.
4. To identify priority issues for advocacy and programming in prevention and response to gender-based violence among the transwomen in the greater Kampala metropolitan area, Uganda.

Uganda 2020-11-17 2023-11-17 Social Science and Humanities Non-degree Award
Susanna (Zanna) Clay
ID:
The origins of empathy- Investigating empathy development in the first two years of life
REFNo: SS596ES

Empathy – the sharing and understanding others’ emotions and thoughts – is an essential part of what it means to be human. While empathy underpins our most meaningful social interactions, we lack knowledge about its developmental and evolutionary origins. Thus far, research on empathy development remains limited, something which may have led to inaccurate conclusions that infants lack the capacity for empathy before their second year.. Although the view that infants lack empathy has recently been challenged, current research remains constrained by a lack of research attention as well as suitable methodologies to study early empathy. A key goal of this project is to address these limitations by conducting the first major study of empathy development across the first 2 years of life. By combining observations with novel experimental techniques our goal is study how the cognitive and affective components of empathy emerge.

Another objective is to investigate the impact that the social and cultural environment have on infant socio-emotional development. Research indicates that caregiving and the socio-cultural environment shape infant development, however, there is little research looking into how these factors shape empathy development. In addition, most developmental research so far has been conducted on infants from Western societies, also denoted as WEIRD (Western Educated Industrialised Rich Democratic) whilst ignoring cross-cultural variability. By focusing on a subset of Western societies, current developmental research is thus not representative of global diversity; ignoring insights from cross-cultural variation may lead to inaccurate interpretations.

In order to address this and understand how the socio-cultural environment shapes empathy development, it is essential to study how empathy develops in a more diverse cross-cultural sample. Through doing so, we can also address which aspects of empathy may be learned or socially-mediated, and which might reflect human universals. The current project aims to address this by studying the development of empathy and the influence of the socio-cultural environment. The capacity for empathy has far reaching consequences for how we function as a species and interact with others. A lack of capacity to care about others (empathy) can have many negative consequences for individuals and our societies, including reduced wellbeing, quality of social relationships, crime and mental health. Given the importance of empathy for our social and societal functioning, it is essential to know where empathy comes from and how it is shaped by social and cultural experiences.

This project represents a continuation and extension of the research activities of a current and approved research project, led by Professor Katie Slocombe, running on infant development in the Masindi district of Uganda. This project was approved by UNCST and UVRI (UVRI-045/2017). Our current project uses very similar methods and is planned to be conducted with the same local research assistants and communities who have participated in this research.

UK 2020-11-17 2023-11-17 Social Science and Humanities Degree Award
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