Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Imelda Bates
ID:
Development of a complex quality improvement intervention for timely blood transfusions for the management of postpartum haemorrhage (PPH) in Uganda
REFNo: HS579ES

1. To map out active transfusing facilities and blood centres in two districts in Uganda and create a profile of baseline measures of quality of PPH management and blood transfusion services (e.g. availability of blood, safety of blood, timeliness of referrals of women with PPH, regular measurement of haemoglobin in PPH patients) for each district
2. To determine key barriers to the appropriate management of PPH, including blood transfusion
3. To gain stakeholder buy-in and contribution to a lead-on quality improvement intervention’s design from all levels, with a specific view to feasibility and sustainability
UK 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Alison Elliott
ID: UNCST-2023-R006524
“Establishing a Single-Sex Controlled Human Schistosoma mansoni Infection Model for Uganda: Safety and Dose Finding” (CHI-S-Ug1)
REFNo: HS697ES

Primary objective: To investigate (1) the safety and tolerability and (2) the infectivity of male Schistosoma mansoni (Sm) cercariae in healthy adult Ugandan volunteers with (a) minimal prior exposure to Sm, and (b) intense prior exposure to Sm.
Exploratory objectives: To investigate the kinetics of controlled infection with male Schistosoma mansoni cercariae in healthy adult Ugandan volunteers (a) with minimal prior exposure to Sm, and (b) with intense prior exposure to Sm. To investigate immunological, metabolic and microbiome changes after infection with Schistosoma mansoni male cercariae. To investigate volunteer and wider community understandings of CHI in the context of CHI-S.


UK 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Adegbola Tololupe Adesogan Carola
ID:
FEED THE FUTURE PESTE DES PETITS RUMINANTS VACCINE ASSOCIATE AWARD
REFNo: A77ES

In the course of the pilots, the project will conduct: • A rapid assessment of existing information and surveillance activities to identify the most relevant actions to reinforce surveillance and epidemiological assessments capacity and information. • At least one training workshop to enhance skills and establish epidemiological monitoring systems that meet both disease control and project applied research needs. • Targeted sero-sampling designed for the estimation of the basic reproductive number. • Participation in the investigation of outbreaks and facilitation of the collection of material for viral isolation and genomic analysis. • Mapping of virus flows and modeling of disease transmission as an approach to integrating data from diverse sources. • Areas targeted will be points of high virus circulation and will have substantial levels of PPR antibody; the project will measure the impact of vaccination on herd immunity and the frequency of disease events.
USA 2020-11-17 2023-11-17 Agricultural Sciences Non-degree Award
John  Ssempebwa
ID: UNCST-2020-R014966
ASSESSMENT OF STATUS AND DEVELOPMENT OF FRAMEWORK AND GUIDELINES TO IMPROVE HEALTH AND SAFETY OF SWIMMING POOLS IN THE GREATER KAMPALA METROPOLITAN AREA, UGANDA
REFNo: HS730ES

Objectives
1. To determine the physio-chemical and microbiological quality of water in swimming pools.
2. To determine the knowledge, and practices of swimmers and operators regarding safety of
swimming pools.
3. To establish the hygienic and safety status at the swimming pools premises.
4. To establish a framework and guidelines to regulate operation of swimming pools in Uganda.
Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Jonathan Nsamba
ID: UNCST-2024-R003888
Body composition and muscular health of children and adolescents diagnosed with type 1 diabetes mellitus in Uganda
REFNo: HS759ES

1. To determine the body composition of children and adolescents diagnosed with T1DM as compared to their closely matched sex and age controls.
2. To determine the hand grip strength of children and adolescents diagnosed with T1DM as compared to their closely matched sex and age controls.
3. To examine the associations between dietary intake patterns, physical activity, nutrition status and body composition among children and adolescents diagnosed with T1DM
4. To understand the perceptions of newly diagnosed Type 1 Diabetes Mellitus children and adolescents about their disease status, barriers and facilitators to self-care.

Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Degree Award
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"A prosperous Science and Technology Led Ugandan Society."