Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Janet SEELEY
ID:
Menstrual health interventions, schooling and mental health symptoms among Ugandan students (MENISCUS): a school-based cluster-randomised trial.
REFNo: HS1525ES

1. To evaluate whether the MENISCUS intervention improves educational attainment and reduces mental health symptoms (primary outcomes) among Secondary girls in Uganda.

2. To evaluate whether the MENISCUS intervention improves: i) knowledge of puberty and menstruation; attitudes towards menstruation (girls and boys); ii) menstrual practices at last menstrual period (LMP); iii) knowledge and practice of pain management during LMP; iv) self-efficacy in addressing menstrual needs experiences at LMP; v) quality of life and happiness; vi) school and class absence during menses (nested cohort); vii) school and class absence overall (nested cohort); viii) prevalence of urogenital infections (bacterial vaginosis, vaginal yeast and urinary tract infections)
3. To evaluate the costs of setting up and running the intervention package, the unit cost per female student reached, and the incremental cost-effectiveness of the intervention per unit increase in selected policy-relevant outcomes, relative to optimised usual care
4. To assess whether the intervention was implemented with fidelity, and to understand the contextual factors affecting implementation, the acceptability to participants, and the intervention mechanisms. We will achieve this through a process evaluation including quantitative indicators and qualitative data collected from in-depth interviews and focus group discussions.
5. To assess the policy environment around menstrual health in Uganda, focusing on how implementing the intervention contributes to, and aligns with, the attainment of the Government policy objectives on menstruation management in schools. We will assess the policy/regulatory frameworks to which the outcomes of the intervention contribute, identify the supportive and constraining factors to the implementation of the policy guidelines and how the findings of the intervention inform refinement of current policy.

UK 2021-07-14 2024-07-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Damalie Nakanjako
ID: UNCST-2019-R000383
Mobile Phone-based patient follow-up Package with Medical Intervention for HIV-infected adults to promote social distancing during and after the COVID19 pandemic lockdown crisis
REFNo: HS945ES

Objectives
1.To pilot use of a Mobile Phone-based patient follow-up Package with virtual Medical Interventions (PMI) among adults receiving antiretroviral therapy (ART) at the Mulago ISS clinic.
2.To determine the effect of a PMI on the number of physical clinical visits by patients receiving ART at the Mulago ISS clinic during the one-year study period.
3.To determine the effect of PMI on continuity of ART medication during the COVID19 pandemic crisis period.
4.To determine the acceptability of the PMI approach to follow up of patients receiving long-term ART by patients and care providers at the Mulago ISS clinic

Uganda 2021-07-13 2024-07-13 Medical and Health Sciences Non-degree Award
Christina Bergey Marie
ID: UNCST-2020-R014338
Genetic survey of bloodborne pathogens and investigation of malaria response in sanctuary chimpanzees
REFNo: NS139ES

Our proposed study has three main objectives:

1. To determine which blood-borne pathogens sanctuary chimpanzees carry, with a particular interest in those which can be transmitted from human to chimpanzee (anthroponoses) and vice versa (zoonoses);

2. To diagnose malaria infection in sanctuary chimpanzees and determine which malaria parasite species are present, with a particular interest in human malaria that may be infecting the chimpanzees; and

3. To describe the genetic mechanisms underlying the chimpanzee immune system response to malaria, and contrast this with that of humans.
USA 2021-07-13 2024-07-13 Natural Sciences Non-degree Award
Anthony  Fuller
ID:
Assessment of Accuracy, Precision, and Feasibility of a Handheld Near-Infrared Light Device (InfraScanner 2000™) in Detecting Subdural and Epidural Hematomas in Patients Admitted to Mbarara Regional Referral Hospital
REFNo: HS1010ES

Aim 1: Determine whether the InfraScanner 2000™ detects epidural and/or subdural hematomas with adequate precision relative to CT scans to be used as a diagnostic tool for epidural and/or subdural hematomas.

Aim 2: Use these findings to inform the feasibility of conducting a future trial in which the InfraScanner 2000™ is used as a stand-alone diagnostic tool for intracranial hematomas, and therein, to determine candidacy for decompressive craniotomies in patients who suffer TBIs in places where CT scans are not available.
USA 2021-07-13 2024-07-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Vittorio Bassi
ID:
Covid-19 and the value of relationships in informal economies
REFNo: SS633ES

The overall goal of the study is to implement two exploratory phone surveys of a representative sample of Micro, Small and Medium enterprises (MSMEs) and their employees in Uganda. The survey is designed to document challenges firms are facing in investing and hiring workers during the covid-19 pandemic. In addition, the first phone survey will also embed a nudging experiment aimed at helping workers search for jobs and regain employment in the wake of the pandemic. This is an urgent study that forms a continued commitment of the researchers under BRAC Uganda partnership with Ministry of Trade, Industry and Cooperatives under Directorate of Micro and Small Medium Enterprises (MSMEs) to provide insights and learning on how the covid-19 shock has affected firm owners and employees’ relationships during the lockdown.
Italy 2021-07-13 2024-07-13 Social Science and Humanities Non-degree Award
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