Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Pontiano  Kaleebu
ID: UNCST-2020-R019901
Clinical characterization and preparedness for COVID-19 disease (CCP)
REFNo: HS1041ES

• Describe the clinical features of COVID-19 and monitor the progress of all hospitalized patients including what is working and what is not.
• Describe, where appropriate, the response to treatment, including supportive care and novel therapeutics.
• Observe, where appropriate and feasible, pathogen replication, excretion and evolution, within the host, and identify determinants of severity and transmission using high throughput sequencing of pathogen genomes obtained from respiratory tract, blood, urine, stool and other samples.
• Characterise, where appropriate and feasible, the host responses to infection and therapy over time, including innate and acquired immune responses, levels of immune signaling molecules in relevant body compartments and gene expression profiles in peripheral blood.
• Understand transmissibility and the probabilities of different clinical outcomes following exposure and infection.
• To describe COVID 19 related haematological and biochemical changes

Uganda 2020-12-08 2023-12-08 Medical and Health Sciences Non-degree Award
Charity Okaba
ID:
Understanding Community-oriented Prosocial Behaviors in Uganda
REFNo: SS641ES

The proposed study aims to investigate and contextually define relevant categories of prosocial behaviors and the demographics and individual characteristics associated with such prosocial behaviors, in Uganda. There are three major reasons that motivate why this research is much needed:
Firstly, this research will aim to define prosocial behaviors in the context of Uganda and demonstrate methods to capture and categorize them, both of which have currently been defined by Western research. We seek to understand the variations in the way people perceive and engage in prosocial behaviors in an under-researched context and contribute our results to the existing body of literature.
Second, this research will further explore how individual characteristics (both demographics and psychographic) are associated with different contextualized categories of prosocial behaviors. Existing research has largely explored demographic links to some extent but has overlooked the link between other individual differences to the level of engagement with prosocial behaviors.
Finally, the results from the proposed research will have far-reaching impacts for social and community development, including but not limited to community-based groups, as well as researchers, practitioners, and policymakers. Our research can be easily used to guide the design and framing of communication to encourage engagement in prosocial behavior that promote community development and improve welfare.
Uganda 2020-12-08 2023-12-08 Social Science and Humanities Non-degree Award
Daniel  Kaye Kabonge
ID:
COUNTRY-WIDE ESTIMATES OF THE INCIDENCE OF ABORTION AND ABORTION-RELATED MORBIDITY IN UGANDA
REFNo: HS1074ES

To systematically generate reliable nationwide evidence on the scale and distribution of the burden of unsafe abortion in Uganda and its effects, so as to engage policy and decision makers through further discussion of the subject in a amore contextualized manner. Specifically, to establish the incidence and distribution of unsafe abortion in Uganda, to estimate the effects of the burden of unsafe abortion in Uganda (in terms of magnitude of abortion complications) and to provide recommendations for decision makers on future programming for abortion care in Uganda
Uganda 2020-12-08 2023-12-08 Medical and Health Sciences Non-degree Award
Laban Musinguzi Kashaija
ID: UNCST-2020-R014407
The Situation of, and Impact of COVID-19 on school going girls and young women in Uganda
REFNo: SS676ES

The study will be guided by five specific objectives, which include the following;
1. Prevalence estimate of early marriages and adolescent pregnancies among school going girls during the Covid-19 pandemic in Uganda.
2. Describe the drivers of sexual engagement among school going girls during the Covid-19 pandemic.
3. Assess the level of participation of school going girls in available learning opportunities and their continued interest in education during the pandemic and the post-Covid-19 period.
4. Examine the involvement of school going girls in economic activities during the Covid-19 pandemic and the effects of this on the lives of school going girls.
5. Identify possible innovations to support girls to continue with education during the COVID-19 Pandemic and in the aftermath of the pandemic.

Uganda 2020-12-04 2023-12-04 Social Science and Humanities Non-degree Award
Richard Nyeko
ID: UNCST-2021-R012815
Prognostic factors, Clinical outcomes and Survival among childhood cancer patients in northern Uganda: a five-year retrospective review of records
REFNo: HS884ES

General objective
To determine the prognostic factors, clinical outcomes and survival among children with cancer in northern Uganda treated in a low resourced non-specialized upcountry cancer treatment centre over a five year period from January 2014 to December 2018
Specific objectives
1. To determine the outcomes of children with cancer in northern Uganda treated at St. Mary’s hospital Lacor from January 2014 to December 2018
2. To establish the 1- and 2-year survival rates of children with cancer in northern Uganda treated at St. Mary’s hospital Lacor from January 2014 to December 2018
3. To determine the predictors of outcomes among children with cancer in northern Uganda treated at St. Mary’s hospital Lacor from January 2014 to December 2018

Uganda 2020-12-03 2023-12-03 Medical and Health Sciences Non-degree Award
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