Kennedy Kassaza
ID: UNCST-2019-R000615
|
Development of a multiplex mismatch amplification mutation assay and ex-vivo cytokine release analysis to stratify Cryptococcal meningitis infections in Uganda
REFNo: HS3076ES
1. To determine the types of cytokines released in ex-vivo cytokines stimulation assay by antigens prepared from the alternate and reference alleles for the genes: CNAG_04922; CNAG_07837, CNAG_06422 and CNAG_00363.
2. To quantify the IL2 cytokine released and determine the relationship between C. neoformans gene alleles and levels of IL2 cytokine released
3. To design an allele specific PCR assay referred to as mismatch amplification mutation assay (MAMA PCR) for rapid detection of presence of alternate alleles for C. neoformans genes: CNAG_04922; CNAG_07837, CNAG_06422 and CNAG_00363 in clinical isolates
|
Uganda |
2024-06-12 14:23:42 |
2027-06-12 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
ucama Patrick ufoymungu
ID: UNCST-2023-R006573
|
PERFORMANCE OF APRI SCORE COMPARED TO FIBROSCAN IN THE ASSESSMENT OF FIBROSIS AMONG ADULTS WITH CHRONIC HEPATITIS B INFECTION AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS4174ES
3. To determine the degree of agreement or disagreement between FibroScan and APRI Score in assessing the presence or absence of liver fibrosis among adults with Chronic Hepatitis B infection at the hepatitis clinic of Mbarara Regional Referral Hospital.,2. To identify the factors associated with liver fibrosis among adults with Chronic Hepatitis B infection at the hepatitis clinic of Mbarara Regional Referral Hospital.,1. To determine the prevalence of liver fibrosis among adults with chronic hepatitis B infection by using FibroScan and APRI Score at the hepatitis clinic of Mbarara Regional Referral Hospital.,To compare the performance of APRI score to Fibroscan in the assessment of fibrosis among adults with chronic hepatitis B infection at Mbarara Regional Referral Hospital.,
|
Burundi |
2024-06-12 14:22:59 |
2027-06-12 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Orla Walsh
ID:
|
Staff Experiences of PAIRS Training
REFNo: HS4309ES
To determine the availability and adequacy of resuscitation equipment and supplies in the selected health centres. ,To explore the experiences of staff who have received PAIRS training and compare responses of staff within these centres who have not participated in PAIRS. ,
|
Ireland |
2024-06-12 14:22:12 |
2027-06-12 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Maria Kasirye Ella
ID:
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INFLUENCE OF SIGNIFICANT DEPRESSION SYMPTOMS ON ADHERENCE TO TENOFOVIR BASED ANTIRETROVIRAL THERAPY AT 24 MONTHS AMONG 18 TO 35-YEAR-OLD WOMEN LIVING WITH HIV IN KAMPALA; A LONGITUDINAL STUDY
REFNo: HS4301ES
3. To determine the association between the longitudinal patterns of significant depression symptoms and adherence to ART in 18 to 35-year-old women living with HIV on Tenofovir-based regimens in Kampala district.,2. To assess the longitudinal patterns of significant depression symptoms in 18 to 35-year-old women living with HIV on Tenofovir-based regimens in Kampala district.,1. To determine the baseline prevalence of significant depression symptoms in 18 to 35-year-old women living with HIV on Tenofovir-based regimens in Kampala district.,• To determine the longitudinal patterns of significant depression symptoms and their influence on antiretroviral therapy adherence among 18 to 35-year-old women living with HIV on Tenofovir-based regimens in Kampala, Uganda.,
|
Uganda |
2024-06-12 14:21:19 |
2027-06-12 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Job Kalema
ID: UNCST-2021-R013087
|
PEER ASSESSMENT FRAMEWORK TO SUPPORT GROUP-BASED ASSESSMENT IN E-LEARNING ENVIRONMENT FOR HIGHER INSTITUTIONS OF LEARNING
REFNo: SIR341ES
To evaluate the designed peer assessment framework using the DeLone and McLean model.,To design a peer assessment framework for group-based assessment based on the requirements gathered in (i) above.,To gather the requirements of group-based assessment frameworks used in universities.,The purpose of this study is to build the peer assessment framework for group-based assessment that improves interactions in the online learning environment for Universities.,
|
Uganda |
2024-06-12 14:20:29 |
2027-06-12 |
Engineering and Technology |
Non-Clinical Trial |
Degree Award |
|
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
|
Validation of a cross-outbreak stigma scale in infectious disease outbreak-affected communities (2022 Ugandan Ebola outbreak component )
REFNo: SS2727ES
: Understand how stigma impacts outbreak control (and vice versa), and how this stigma could be validly and effectively assessed.,Use the stigma scale in three different outbreak contexts (specifically communities affected by Ebola in Uganda for purposes of this application) to measure disease-related stigma.,Co-develop and validate a cross-outbreak stigma scale,To administer and validate a stigma scale to assist with recognition and reduction of infectious disease outbreak-related stigma in affected communities (specifically communities affected by Ebola in Uganda).,
|
Uganda |
2024-06-12 14:16:19 |
2027-06-12 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Leonsio Matagi
ID: UNCST-2024-R004055
|
The feasibility and acceptability of the co-administration of ivermectin and albendazole vs albendazole alone, in the frame of mass drug administration to school-aged children in Uganda.
REFNo: SS2755ES
To assess the feasibility (including aspects of training, materials and processes) of the co-administration of ivermectin and albendazole compared to albendazole alone at small-scale in the frame of school-based MDA in Uganda
To evaluate the acceptability and identify potential barriers and enablers of the introduction of co-administered ivermectin and albendazole for beneficiaries (pupils, parents/caretakers)
|
Uganda |
2024-06-10 8:54:51 |
2027-06-10 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Daniela Acosta
ID: UNCST-2024-R003832
|
Chimpanzee Intercommunity Competition: Measuring Benefits and Costs at the Group Level.
REFNo: NS826ES
I aim to investigate questions related to the causes and consequences of territorial expansion and contraction at the group level due to intergroup competition. Specifically, I am interested in (i) understanding changes in ranging patterns, habitat use, reproductive success, resource availability and social relationships before, during, and after territorial shifts; (ii) examining decision-making processes during patrolling behavior; and (iii) identifying the mechanisms in which sociality influences group level cooperation.
|
Colombia |
2024-06-10 8:23:29 |
2027-06-10 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
|
Picos Ariho
ID:
|
Preventive Diplomacy and the (De-)escalating Armed conflicts in Eastern Democratic Republic of Congo: A case of the International Conference of the Great Lakes Region.
REFNo: SS2620ES
1. Examine what accounts to the resurgence of the M23 Movement following its military defeat a decade ago.
2. Assess the diplomatic machinery potential of the M23 and armed conflicts.
3. Re-evaluate the promise of preventive diplomacy in both bilateral and multilateral relations with ending armed conflicts in Africa's great lakes region.
|
Uganda |
2024-06-06 17:41:29 |
2027-06-06 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Innocent Mutyaba
ID: UNCST-2021-R012218
|
Identifying Predictors of Kaposi Sarcoma Immune Reconstitution Inflammatory Syndrome
REFNo: HS2151ES
We propose to utilize the ACSR ARKS study specimen biorepository and clinical database to identify predictors and biomarkers of KS-IRIS in the ARKS cohort.
To determine if select clinical parameters, plasma cytokines, and KSHV burden measured at time of KS-IRIS symptom onset could serve as biomarkers of prevalent KS-IRIS. We will develop a predictive model of KS-IRIS utilizing the ARKS study to extend the findings from the HIPPOS study.
To identify baseline predictors of incident KS-IRIS among adults with early-stage KS initiating ART.,
|
Uganda |
2024-06-06 17:40:22 |
2027-06-06 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Elisa Macchi
ID: UNCST-2023-R004097
|
Would you hire a female mechanic? Experimental evidence
from motor-mechanics managers in Uganda
REFNo: SS2574ES
1. To examine the gender desparities in hiring among managers in the motor-mechanic industry.
2. To access the impact of monitoring towards gender discrimination
3. To measure the impact of training on decisions to hire and gender discrimination.
4. Measure hiring managers’ misperception about jobseekers on-the-job abilities and trustworthiness.
|
Italy |
2024-06-06 17:39:07 |
2027-06-06 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
Grace Kagoro
ID: UNCST-2021-R013951
|
Improved mechanisms for climate change adaptation for sustainable food production
REFNo: NS705ES
Main Objective
1. To improve climate smart agriculture mechanisms and land management practices to cope with climatic variability.
Specific Objectives
1. To establish climatic related environmental hazards, risks & vulnerabilities in small holder farming of SW Uganda.
2. To determine climate smart agricultural practices for adoption to diversify and increase food production in climatic hazard-prone areas.
3. To optimize laboratory infrastructure for analytical capacities in soil, food profiling and plant micro-propagation at MUST.
4. To develop farmer-led crop production and climate monitoring systems for informed food production.
|
Uganda |
2024-06-05 17:47:58 |
2027-06-05 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
|
Linda Calabrese
ID:
|
Comparative analysis of FDI in Uganda
REFNo: SS1960ES
This research aims to understand whether investment from China is different from that from other countries in terms of its implications for host low- and middle-income countries (LMICs). I operationalise the research in the context of the spillovers generated by Chinese firms and foreign-non Chinese firms on domestic firms. I focus on spillovers because these are important channels of durable productivity transfers between foreign and domestic firms, but one that has mainly been investigated quantitatively and with little comparative analysis.
|
Italy |
2024-06-05 17:46:42 |
2027-06-05 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
PAULA NJERU
ID:
|
Utility of An Epilepsy Self-Management And Resilience Technical (SMART) APP for Adolescents and Young Adults
REFNo: HS3799ES
To identify specific improvements for the APP that will make it more useful for AWE and young adults.,To understand aspects of the APP that AWE and young adults derive the greatest benefit from.,To understand the perspectives of adolescents and young adults with epilepsy about using the SMART APP. ,To characterize the experiences of adolescents and young adults with epilepsy while using the SMART APP, pinpoint the essential elements of the APP that adolescents and young adults with epilepsy find most advantageous, and propose specific enhancements to further improve the APP,
|
Kenya |
2024-06-05 17:45:41 |
2027-06-05 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Richard Rwabuhinga
ID:
|
Influence of Competency and performance on Employability in Uganda; A case study of Mountains of the Moon and United Pentecostal Universities
REFNo: HS3058ES
4. The establish the impact of competencies on interpersonal skills of graduates from Mountains of the Moon and United Pentecostal Universities in Mid-western Uganda,3. To find out the influence of competence on problem solving skills of education graduates from Mountains of the Moon and United Pentecostal Universities in Mid-western Uganda.,2. To establish the influence of competence on communication skills among education graduates from Mountains of the Moon and United Pentecostal Universities in Mid-western Uganda.,1. To establish the influence of competence on academic skills among education graduates from Mountains of the Moon and United Pentecostal Universities in Mid-western Uganda.,
|
Uganda |
2024-06-05 17:44:09 |
2027-06-05 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Cissy Kityo
ID: UNCST-2021-R013663
|
A Phase 2a/2b Study Evaluating Safety, Immunogenicity, and Therapeutic Efficacy of ID93 + GLA-SE Vaccination in Participants with Rifampicin-Susceptible Pulmonary TB
REFNo: HS3834ES
1.2 Secondary Objectives 1.2.1 Phase 2a and 2b: To evaluate the proportion of participants with a quantifiable RS ratio after therapeutic vaccination with ID93 + GLA-SE compared to placebo. 1.2.2 Phase 2a: To evaluate the kinetics of cellular immunogenicity of ID93 + GLA-SE through 12 months post second dose of study product. 1.2.3 Phase 2a: To evaluate the kinetics of humoral immunogenicity of ID93 + GLA-SE through 12 months post second dose of study product. 1.2.4 Phase 2a: To evaluate innate immune changes in response to ID93 + GLA-SE through 2 weeks post second dose of study product. 1.2.5 Phase 2b: To compare therapeutic vaccination with ID93 + GLA-SE, to placebo, with respect to the proportion of participants with TB-related unfavorable outcomes at 540 days after study entry, which is approximately 18 months after start of TB treatment, in subgroups defined by: Hard-to-treat phenotype and not hard-to-treat phenotype, where hard-to-treat phenotype is defined as smear Grade ≥3 and cavitary disease on chest radiograph at TB diagnosis.1.3 Exploratory Objectives 1.3.1 Phase 2a: To compare therapeutic vaccination with ID93 + GLA-SE to placebo, with respect to: • The safety and immunogenicity of ID93 + GLA-SE in participants living with and without HIV. • The quantitative RS ratio at time points relative to vaccination and TB treatment as indicated in the Schedule of Evaluations (SOE). • The magnitude and quality of immune responses with respect to the composition of the intestinal microbiota. 1.3.2 Phase 2b: To compare therapeutic vaccination with ID93 + GLA-SE to placebo, with respect to the proportion of participants with TB-related unfavorable outcomes at 540 days after study entry, which is approximately 18 months after start of TB treatment, adjusted for • Pharmacokinetics (PK) assessments of first-line TB drugs (exposure) during TB treatment as per the SOE. • Levels of participant adherence to standard of care (SOC) TB treatment measured using self-reporting and urine acetyl-isoniazid (AcINH) from start to end of TB treatment. 1.3.3 Phase 2b: To compare therapeutic vaccination with ID93 + GLA-SE to placebo, with respect to the proportion of participants with TB-related unfavorable outcomes at 540 days after study entry, which is approximately 18 months after start of TB treatment, stratified by bacterial burden at start of TB treatment. 1.3.4 Phase 2a and 2b: To develop the composite predictive model of TB drug response by using measures of adherence, drug exposure (PK), immune response, gut microbiota, and participant phenotype. 1.3.5 Phase 2a and 2b: To compare therapeutic vaccination with ID93 + GLA-SE to placebo, with respect to proportion of participants with sputum culture conversion at baseline at time of randomization and at Step 2, Days 30, 120, and 150, which are approximately 2, 5, and 6 months after start of TB treatment. 1.3.6 Phase 2a and 2b: To compare therapeutic vaccination with ID93 + GLA-SE to placebo, with respect to cumulative relapse from end of TB treatment up to end of study follow-up, that is, Step 2, Days 420, 450, 480, and 510, for Groups 1, 2, 3 (&5), and 4 (&5), respectively. 1.3.7 Phase 2a and 2b: To compare therapeutic vaccination with ID93 + GLA-SE to placebo, with respect to lung function and health-related quality of life, as measured by spirometry and the St. George’s Respiratory Questionnaire. 1.3.8 Phase 2a and 2b: To compare the within-person change in lung function tests over time from the first dose of therapeutic vaccination with ID93 + GLA-SE to placebo. 1.3.9 Phase 2a and 2b: To compare therapeutic vaccination with ID93 + GLA-SE to placebo, with respect to resolution of transcriptomic biomarkers of TB disease. 1.3.10 Phase 2b: To identify correlates of protection for unfavorable TB outcomes. 1.3.11 Phase 2b: To estimate the effect of the vaccine on the proportion of participants with TB-related unfavorable outcomes among participants living with and without HIV. 1.3.12 Phase 2a and 2b: To conduct analyses related to furthering the understanding of TB, HIV, immunology, vaccines, and clinical trial conduct.,1.1 Primary Objectives 1.1.1 Phase 2a and 2b: To evaluate safety of a two-dose ID93 + GLA-SE vaccine regimen administered 60 days apart on Step 2, Days 0 and 60, with TB treatment administered, at approximately: 1.1.1.1 Months 4 and 6 after start of TB treatment (Group 1) 1.1.1.2 Months 3 and 5 after start of TB treatment (Group 2) 1.1.1.3 Months 2 and 4 after start of TB treatment (Group 3 and Group 5, if this vaccination schedule is adopted for Group 5) 1.1.1.4 Months 1 and 3 after start of TB treatment (Group 4 and Group 5, if this vaccination schedule is adopted for Group 5) 1.1.2 Phase 2a and 2b: To determine if therapeutic vaccination with ID93 + GLA-SE will increase the magnitude of vaccine-specific cellular responses compared to placebo at 2 weeks post second dose of study product. 1.1.3 Phase 2b: To estimate the effect of the vaccine on the proportion of participants with TB-related unfavorable outcomes (treatment failure, TB recurrence, or death due to TB) at Day 540 after study entry, which is approximately 18 months after start of TB treatment (Group 5 combined with either Group 3 or Group 4, depending on which vaccination schedule is selected for Group 5).,
|
Uganda |
2024-06-05 17:42:17 |
2027-06-05 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
KIYINGI MARTIN
ID:
|
A critical review of [Nature of existence]; to establish "Existential Scope of education", the "Problem of education", "Forms of inquiry” and “Perspectives of knowledge”, in Uganda. A case of selected education policy institutions and Universities in Uganda.
REFNo: SS2573ES
4. To explore possibility of Physical (Truth, Empirical Knowledge and Reality), to alleviate the prevailing and emerging, “Existential” and “Physical” problems; probably the prevailing “Scope of education” is focused at mitigation and adaptation rational consequential [Physical problems (Outcomes)] of own continuous existential Causation and Processing. ,3. To explore how the [Nature of existence] influence Existential (Truth, Knowledge & Reality) and establish if possibility of (Truth, Knowledge and Reality) is limited to only the physical possibility of existence.,2. To explore the “Problem of education” and establish how the [Existential forms of inquiry] based on the [Nature of existence] influence the [Perspectives (Viewpoint) of knowledge]. ,1. To explore the fundamental [Nature of existence], a fundamentalism of [Existential Identity] of all species, the “Scope of education” and basis for respective [Existential forms of inquiry (Sensory response to stimulus)].,
|
Uganda |
2024-06-05 17:39:12 |
2027-06-05 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Cornelius Sendagire
ID: UNCST-2021-R004351
|
Potentially modifiable factors to improve outcomes of mechanically ventilated patients in ICUs in Resource-limited settings (MOTIVATE-ICU)
REFNo: HS4040ES
To assess outcomes associated with tracheostomy timing in IMV patients in LMIC ICUs.,To determine non-modifiable patient-level factors associated with ICU mortality, ICU length of stay and duration of mechanical ventilation among LMIC ICU patients. ,To identify potentially modifiable factors associated with ICU mortality, ICU length of stay and duration of mechanical ventilation among LMIC ICU patients. ,
|
Uganda |
2024-06-05 17:37:52 |
2027-06-05 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Jack Turihohabwe
ID:
|
A deep learning model for early prediction and diagnosis of Late Blight Disease in Irish potatoes: A case of Kigezi Region RefNo:MUST-2023-1308
REFNo: SIR323ES
The major objective of the research study is improving early prediction and accurate diagnosis of late blight disease among Irish potato farmers in Kigezi.
|
Uganda |
2024-06-05 17:36:19 |
2027-06-05 |
Engineering and Technology |
Non-Clinical Trial |
Degree Award |
|
Emmanuel Menya
ID:
|
Torrefaction of Banana Value Chain-Based Wastes Available in Uganda for Fuel (TorrCoal Project)
REFNo: SIR172ES
Main Objective
To investigate the torrefaction potential of banana value chain-based wastes available in Uganda for fuel.
Specific Objectives
• To characterize the underutilized banana value chain-based wastes
• To optimize the torrefaction conditions for production of bio-coal from selected banana value chain-based wastes
• To assess the quality and performance of briquettes generated from the torrefied banana waste
|
Uganda |
2024-06-05 17:35:18 |
2027-06-05 |
Engineering and Technology |
Non-Clinical Trial |
Degree Award |
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